Antimalarials

Cytotoxic kurubasch aldehyde from Trichilia emetica

Mass Spectrometry / Multidisciplinary / Humans / Mice / Animals / Natural Product / Meliaceae / Plant Roots / Sesquiterpenes / Plasmodium falciparum / Antimalarials / Optical Rotation / Molecular Structure / Breast Cancer Cells / Natural Product / Meliaceae / Plant Roots / Sesquiterpenes / Plasmodium falciparum / Antimalarials / Optical Rotation / Molecular Structure / Breast Cancer Cells

Small molecule Plasmodium FKBP35 inhibitor as a potential antimalaria agent

Feasibility Studies / Protein Sequence Analysis / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Amino Acid Sequence / Protein Binding / Cell Survival / Amino Acid Sequence / Protein Binding / Cell Survival

Analogs of natural aminoacyl-tRNA synthetase inhibitors clear malaria in vivo

Enzyme Inhibitors / Multidisciplinary / Humans / Mice / Animals / Plasmodium falciparum / Antimalarials / Plasmodium falciparum / Antimalarials

Systemic lupus erythematosus and pregnancy

Immunology / Kidney diseases / Pregnancy / Humans / Systemic Lupus Erythematosus / Female / Ovulation Induction / High risk pregnancy / Aspirin / Primary Antiphospholipid Syndrome / Clinical Sciences / Newborn Infant / Adult / Public health systems and services research / Antimalarials / Cesarean Section / Preconception Care / Ribonucleoproteins / Fetal death / Glucocorticoids / Prenatal Care / Pregnancy Outcome / Azathioprine / Pre Eclampsia / Autoantigens / Female / Ovulation Induction / High risk pregnancy / Aspirin / Primary Antiphospholipid Syndrome / Clinical Sciences / Newborn Infant / Adult / Public health systems and services research / Antimalarials / Cesarean Section / Preconception Care / Ribonucleoproteins / Fetal death / Glucocorticoids / Prenatal Care / Pregnancy Outcome / Azathioprine / Pre Eclampsia / Autoantigens

Plasmodium falciparum signal peptide peptidase is a promising drug target against blood stage malaria

Gene Silencing / Humans / Animals / Drug Design / Biochemical / Protease Inhibitors / Plasmodium falciparum / Antimalarials / Protein Conformation / Amino Acid Sequence / Erythrocytes / Drug Targeting / Carbamates / Biochemistry and cell biology / Protease Inhibitors / Plasmodium falciparum / Antimalarials / Protein Conformation / Amino Acid Sequence / Erythrocytes / Drug Targeting / Carbamates / Biochemistry and cell biology

Drug resistance associated genetic polymorphisms in Plasmodium falciparum and Plasmodium vivax collected in Honduras, Central America

Medical Microbiology / Malaria / Humans / Honduras / Drug Resistance / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Chloroquine / Plasmodium Vivax / Primaquine / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Chloroquine / Plasmodium Vivax / Primaquine

Eosin B as a Novel Antimalarial Agent for Drug-Resistant Plasmodium falciparum

Microbiology / Medical Microbiology / Cell Culture / Toxoplasma gondii / Cell line / Humans / Animals / Drug Resistance / Life Cycle / Enzyme / Mode of action / Research Needs / Active site / Thioredoxin / Plasmodium falciparum / Antimalarials / Antimicrobial agents / Multienzyme complexes / Human Fibroblasts / Glutathione Reductase / Thioredoxin reductase / Dihydrofolate Reductase / Humans / Animals / Drug Resistance / Life Cycle / Enzyme / Mode of action / Research Needs / Active site / Thioredoxin / Plasmodium falciparum / Antimalarials / Antimicrobial agents / Multienzyme complexes / Human Fibroblasts / Glutathione Reductase / Thioredoxin reductase / Dihydrofolate Reductase

A Novel Antiprotozoal Aminosteroid from Saracha punctata

Natural Products / Medicinal Plants / Biological Sciences / Animals / CHEMICAL SCIENCES / Trypanosoma Cruzi / Antimalarials / Natural / Trypanocidal Agents / Plasmodium berghei / Trypanosoma Cruzi / Antimalarials / Natural / Trypanocidal Agents / Plasmodium berghei

Low-dose primaquine for falciparum malaria

Medical Microbiology / Humans / Female / Male / Clinical Sciences / Antimalarials / Primaquine / Antimalarials / Primaquine

Fansidar resistant falciparum malaria acquired in South East Asia

Microbiology / Malaysia / Medical Microbiology / Malaria / Humans / Female / Microbial genetic and drug resistance / Pyrimethamine / Sulfadoxine / Sulfanilamides / Adult / Public health systems and services research / Plasmodium falciparum / Antimalarials / Female / Microbial genetic and drug resistance / Pyrimethamine / Sulfadoxine / Sulfanilamides / Adult / Public health systems and services research / Plasmodium falciparum / Antimalarials

Valproic Acid as a Potential Inhibitor of Plasmodium falciparum Histone Deacetylase 1 (PfHDAC1): An in Silico Approach

Genetics / Molecular Dynamics / Humans / HIstone Deacetylase / Docking / Molecular sciences / Valproic Acid / Plasmodium falciparum / Antimalarials / Binding Energy / Protozoan Proteins / Histone deacetylase inhibitors / Molecular sciences / Valproic Acid / Plasmodium falciparum / Antimalarials / Binding Energy / Protozoan Proteins / Histone deacetylase inhibitors

Antimalarial drug response of Plasmodium falciparum from Zaria, Nigeria

Microbiology / Medical Microbiology / Nigeria / Humans / Child / Animals / Drug Resistance / Infant / Pyrimethamine / Sulfadoxine / Public health systems and services research / Plasmodium falciparum / Antimalarials / Quinine / Chloroquine / Mefloquine / Animals / Drug Resistance / Infant / Pyrimethamine / Sulfadoxine / Public health systems and services research / Plasmodium falciparum / Antimalarials / Quinine / Chloroquine / Mefloquine

Structural requirements of 3-carboxyl-4(1H)-quinolones as potential antimalarials from 2D and 3D QSAR analysis

Computer Software / Quantitative Structure Activity Relationship / Quinolones / Antimalarials / THEORETICAL AND COMPUTATIONAL CHEMISTRY / Molecular Conformation / Static Electricity / Biochemistry and cell biology / Molecular Conformation / Static Electricity / Biochemistry and cell biology

Structural requirements of 3-carboxyl-4(1H)-quinolones as potential antimalarials from 2D and 3D QSAR analysis

Computer Software / Quantitative Structure Activity Relationship / Quinolones / Antimalarials / THEORETICAL AND COMPUTATIONAL CHEMISTRY / Molecular Conformation / Static Electricity / Biochemistry and cell biology / Molecular Conformation / Static Electricity / Biochemistry and cell biology

Structural basis of malaria parasite lysyl-tRNA synthetase inhibition by cladosporin

Macromolecular X-Ray Crystallography / Biological Sciences / Environmental Sciences / Animals / Isocoumarins / Plasmodium falciparum / Antimalarials / Protein Conformation / Plasmodium falciparum / Antimalarials / Protein Conformation

Failure of a Chloroquine Chemoprophylaxis Program to Adequately Prevent Malaria during Pregnancy in Koupela District, Burkina Faso

West Africa / Treatment Outcome / Adolescent / Multivariate Analysis / Biological Sciences / Insecticides / Pregnancy / Humans / Low Birth Weight / Burkina Faso / Female / Animals / Chemoprevention / Placental Malaria / Newborn Infant / Adult / Plasmodium falciparum / Antimalarials / Culicidae / Pregnant Women / Antenatal Care / Intermittent Preventive Treatment / Chloroquine / Cross sectional Study / Cross Sectional Studies / Clinical Infectious Diseases / Confidence Interval / Risk Ratio / Mefloquine / Insecticides / Pregnancy / Humans / Low Birth Weight / Burkina Faso / Female / Animals / Chemoprevention / Placental Malaria / Newborn Infant / Adult / Plasmodium falciparum / Antimalarials / Culicidae / Pregnant Women / Antenatal Care / Intermittent Preventive Treatment / Chloroquine / Cross sectional Study / Cross Sectional Studies / Clinical Infectious Diseases / Confidence Interval / Risk Ratio / Mefloquine

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