Antineoplastic Agents - Page 3

An aza-macrocycle containing maltolic side-arms (maltonis) as potential drug against human pediatric sarcomas

Cell Cycle / DNA damage / Apoptosis / Humans / Child / Mice / Animals / Sarcoma / Cell Proliferation / Antineoplastic Agents / Heterocyclic compounds / Mesenchymal Stromal Cells / Gene expression profiling / Mice / Animals / Sarcoma / Cell Proliferation / Antineoplastic Agents / Heterocyclic compounds / Mesenchymal Stromal Cells / Gene expression profiling

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Fragment-based design of 3-aminopyridine-derived amides as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT)

Organic Chemistry / Cytokines / Enzyme Inhibitors / Macromolecular X-Ray Crystallography / Humans / Amides / Cell Proliferation / Structure activity Relationship / Antineoplastic Agents / Amides / Cell Proliferation / Structure activity Relationship / Antineoplastic Agents

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ASPECCT: panitumumab versus cetuximab for colorectal cancer--authors\' reply

Humans / Female / Male / Monoclonal Antibodies / Antineoplastic Agents / Colorectal Neoplasms

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Melanoma cell sensitivity to Docetaxel-induced apoptosis is determined by class III [beta]-tubulin levels

Molecular Biology / Cancer / Flow Cytometry / Cancer Biology / Apoptosis / Cell line / Humans / Melanoma / Tubulin / Taxanes / Antineoplastic Agents / Biochemistry and cell biology / Proof of Concept / Cell line / Humans / Melanoma / Tubulin / Taxanes / Antineoplastic Agents / Biochemistry and cell biology / Proof of Concept

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Poly-l-asparagine nanocapsules as anticancer drug delivery vehicles

Nanomedicine / Pharmaceutical Chemistry / Lipids / Humans / Peptides / Drug Delivery Systems / Nanocapsules / Particle Size / Surface Active Agents / Drug Carriers / Drug Compounding / Antineoplastic Agents / Drug Delivery Systems / Nanocapsules / Particle Size / Surface Active Agents / Drug Carriers / Drug Compounding / Antineoplastic Agents

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Polymer–drug conjugates as nano-sized medicines

Engineering / Technology / Nanomedicine / Polymers / Biological Sciences / Humans / Drug Delivery Systems / Neoplasms / Individualized Medicine / Drug Carriers / Antineoplastic Agents / Pharmaceutical preparations / Humans / Drug Delivery Systems / Neoplasms / Individualized Medicine / Drug Carriers / Antineoplastic Agents / Pharmaceutical preparations

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Primary Central Nervous System Lymphoma

Cognitive Science / Dentistry / Neurosurgery / Magnetic Resonance Imaging / Radiation Therapy / Treatment Outcome / Adolescent / Lymphoma / Dexamethasone / Brain / Humans / Child / United States / Female / Headache / Male / Young Adult / Infant / Follow-up studies / Incidence / Risk factors / Diagnostic Imaging / Contrast-Enhanced Ultrasound / Clinical Sciences / Aged / Middle Aged / Doxorubicin / Adult / Immunocompromised host / Survival Rate / Methotrexate / Retrospective Studies / Prognosis / Diffuse Large B-Cell Lymphoma / Risk Factors / X ray Computed Tomography / Brain Neoplasm / Cyclophosphamide / Mayo Clinic Proceedings / Antineoplastic Agents / Neurosciences / Nervous System Diseases / Brain Neoplasms / Cognition disorders / immunoglobulin G / Treatment Outcome / Adolescent / Lymphoma / Dexamethasone / Brain / Humans / Child / United States / Female / Headache / Male / Young Adult / Infant / Follow-up studies / Incidence / Risk factors / Diagnostic Imaging / Contrast-Enhanced Ultrasound / Clinical Sciences / Aged / Middle Aged / Doxorubicin / Adult / Immunocompromised host / Survival Rate / Methotrexate / Retrospective Studies / Prognosis / Diffuse Large B-Cell Lymphoma / Risk Factors / X ray Computed Tomography / Brain Neoplasm / Cyclophosphamide / Mayo Clinic Proceedings / Antineoplastic Agents / Neurosciences / Nervous System Diseases / Brain Neoplasms / Cognition disorders / immunoglobulin G

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Functionalized mesoporous silica nanoparticle-based visible light responsive controlled release delivery system

Chemistry / Inorganic Chemistry / Magnetic Materials / Targeted Drug Delivery / Nanoparticles / Transmission Electron Microscopy / Solid State Chemistry / Nanotechnology / Confocal Microscopy / Magnetic Resonance Spectroscopy / Multidisciplinary / Magnetic field / Cell Culture / Humans / Controlled release / Porosity / Medical Biotechnology / Endocytosis / Animals / Light / Folate Receptor / Drug Delivery Systems / Neurons / Hydralazine / CHEMICAL SCIENCES / Cisplatin / Doxorubicin / Spectrum / Rats / Fourier transform infrared spectroscopy / Swine / Surface Properties / Visible Light / Mesoporous / Cysteine / Langmuir / Drug Carriers / Silicon Dioxide / Delayed-Action Preparations / Hydrogen-Ion Concentration / Cell Survival / Antineoplastic Agents / Polyethylene Glycols / acrolein / Transmission Electron Microscopy / Solid State Chemistry / Nanotechnology / Confocal Microscopy / Magnetic Resonance Spectroscopy / Multidisciplinary / Magnetic field / Cell Culture / Humans / Controlled release / Porosity / Medical Biotechnology / Endocytosis / Animals / Light / Folate Receptor / Drug Delivery Systems / Neurons / Hydralazine / CHEMICAL SCIENCES / Cisplatin / Doxorubicin / Spectrum / Rats / Fourier transform infrared spectroscopy / Swine / Surface Properties / Visible Light / Mesoporous / Cysteine / Langmuir / Drug Carriers / Silicon Dioxide / Delayed-Action Preparations / Hydrogen-Ion Concentration / Cell Survival / Antineoplastic Agents / Polyethylene Glycols / acrolein

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Functionalized Mesoporous Silica Nanoparticles: A Possible Strategy to Target Cancer Cells Reducing Peripheral Nervous System Uptake

Chemistry / Inorganic Chemistry / Magnetic Materials / Targeted Drug Delivery / Nanoparticles / Transmission Electron Microscopy / Solid State Chemistry / Nanotechnology / Confocal Microscopy / Magnetic Resonance Spectroscopy / Multidisciplinary / Magnetic field / Cell Culture / Humans / Controlled release / Porosity / Medical Biotechnology / Endocytosis / Animals / Light / Folate Receptor / Drug Delivery Systems / Neurons / Hydralazine / CHEMICAL SCIENCES / Cisplatin / Doxorubicin / Spectrum / Rats / Fourier transform infrared spectroscopy / Swine / Surface Properties / Visible Light / Mesoporous / Cysteine / Langmuir / Drug Carriers / Silicon Dioxide / Delayed-Action Preparations / Hydrogen-Ion Concentration / Cell Survival / Antineoplastic Agents / Polyethylene Glycols / acrolein / Transmission Electron Microscopy / Solid State Chemistry / Nanotechnology / Confocal Microscopy / Magnetic Resonance Spectroscopy / Multidisciplinary / Magnetic field / Cell Culture / Humans / Controlled release / Porosity / Medical Biotechnology / Endocytosis / Animals / Light / Folate Receptor / Drug Delivery Systems / Neurons / Hydralazine / CHEMICAL SCIENCES / Cisplatin / Doxorubicin / Spectrum / Rats / Fourier transform infrared spectroscopy / Swine / Surface Properties / Visible Light / Mesoporous / Cysteine / Langmuir / Drug Carriers / Silicon Dioxide / Delayed-Action Preparations / Hydrogen-Ion Concentration / Cell Survival / Antineoplastic Agents / Polyethylene Glycols / acrolein

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VEGF expression by mesenchymal stem cells contributes to angiogenesis in pancreatic carcinoma

British / Pancreatic Cancer / Cell Differentiation / Humans / Smooth muscle / Mice / Animals / Male / Vascular endothelium / Lentivirus / Monoclonal Antibodies / Bone marrow / Mesenchymal Stem Cell / Epidermal Growth Factor / Endothelial cell / Cell Proliferation / Growth Factor / Human Fibroblasts / Antineoplastic Agents / Blood Vessel / Mesenchymal Stromal Cells / Benzamides / Nude mice / Human Mesenchymal Stem Cells / Mice / Animals / Male / Vascular endothelium / Lentivirus / Monoclonal Antibodies / Bone marrow / Mesenchymal Stem Cell / Epidermal Growth Factor / Endothelial cell / Cell Proliferation / Growth Factor / Human Fibroblasts / Antineoplastic Agents / Blood Vessel / Mesenchymal Stromal Cells / Benzamides / Nude mice / Human Mesenchymal Stem Cells

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Functionalized mesoporous silica nanoparticle-based visible light responsive controlled release delivery system

Chemistry / Inorganic Chemistry / Magnetic Materials / Targeted Drug Delivery / Nanoparticles / Transmission Electron Microscopy / Solid State Chemistry / Nanotechnology / Confocal Microscopy / Magnetic Resonance Spectroscopy / Multidisciplinary / Magnetic field / Cell Culture / Humans / Controlled release / Porosity / Medical Biotechnology / Endocytosis / Animals / Light / Folate Receptor / Drug Delivery Systems / Neurons / Hydralazine / CHEMICAL SCIENCES / Cisplatin / Doxorubicin / Spectrum / Rats / Fourier transform infrared spectroscopy / Swine / Surface Properties / Visible Light / Mesoporous / Cysteine / Langmuir / Drug Carriers / Silicon Dioxide / Delayed-Action Preparations / Hydrogen-Ion Concentration / Cell Survival / Antineoplastic Agents / Polyethylene Glycols / acrolein / Transmission Electron Microscopy / Solid State Chemistry / Nanotechnology / Confocal Microscopy / Magnetic Resonance Spectroscopy / Multidisciplinary / Magnetic field / Cell Culture / Humans / Controlled release / Porosity / Medical Biotechnology / Endocytosis / Animals / Light / Folate Receptor / Drug Delivery Systems / Neurons / Hydralazine / CHEMICAL SCIENCES / Cisplatin / Doxorubicin / Spectrum / Rats / Fourier transform infrared spectroscopy / Swine / Surface Properties / Visible Light / Mesoporous / Cysteine / Langmuir / Drug Carriers / Silicon Dioxide / Delayed-Action Preparations / Hydrogen-Ion Concentration / Cell Survival / Antineoplastic Agents / Polyethylene Glycols / acrolein

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PEG–Ara-C conjugates for controlled release

Organic Chemistry / Dosage Form / Humans / Controlled release / Ph / Mice / Animals / Cell Death / Computer Graphic / NLE / Poly Ethylene Glycol / Time Factors / HeLa cells / Amino Acid Profile / Molecular weight / Residence Time / Dendrimer / Drug Stability / Delayed-Action Preparations / Hydrogen-Ion Concentration / Antineoplastic Agents / Polyethylene Glycols / Molecular Structure / Ad / Mice / Animals / Cell Death / Computer Graphic / NLE / Poly Ethylene Glycol / Time Factors / HeLa cells / Amino Acid Profile / Molecular weight / Residence Time / Dendrimer / Drug Stability / Delayed-Action Preparations / Hydrogen-Ion Concentration / Antineoplastic Agents / Polyethylene Glycols / Molecular Structure / Ad

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Gene transfer into human cord blood−derived CD34+ cells by adeno-associated viral vectors

Stem Cells / Stem Cell Transplantation / Humans / Cord Blood / Experimental / Tretinoin / Hydroxamic Acids / Antineoplastic Agents / Gene Transfer / Tretinoin / Hydroxamic Acids / Antineoplastic Agents / Gene Transfer

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Farnesyltransferase inhibitor BMS-214662 induces apoptosis in B-cell chronic lymphocytic leukemia cells

Membrane Proteins / Enzyme Inhibitors / Leukemia / Mitochondria / Molecular Pharmacology / Apoptosis / Caspases / Cell line / Humans / Chronic Lymphocytic Leukemia / Female / Multiple Myeloma / Male / Cell Death / Cytochrome C / Benzodiazepines / Clinical Sciences / Western blot / Heat Shock Proteins / Protein Conformation / B Lymphocytes / Imidazoles / Mitochondrial Membrane Potential / Antineoplastic Agents / Neurosciences / Conformational Change / Apoptosis / Caspases / Cell line / Humans / Chronic Lymphocytic Leukemia / Female / Multiple Myeloma / Male / Cell Death / Cytochrome C / Benzodiazepines / Clinical Sciences / Western blot / Heat Shock Proteins / Protein Conformation / B Lymphocytes / Imidazoles / Mitochondrial Membrane Potential / Antineoplastic Agents / Neurosciences / Conformational Change

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Primary intracranial fibrosarcoma

Surgery / Radiation Therapy / Treatment Outcome / Adolescent / Primary / Case Report / Humans / Male / Fibrosarcoma / Clinical Sciences / Antineoplastic Agents / Brain Neoplasms / Adjuvant Chemotherapy / Nino / Gliosis / Case Report / Humans / Male / Fibrosarcoma / Clinical Sciences / Antineoplastic Agents / Brain Neoplasms / Adjuvant Chemotherapy / Nino / Gliosis

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Tissue transglutaminase: a new target to reverse cancer drug resistance

Enzyme Inhibitors / Humans / Animals / Amino Acids / Neoplasms / Antineoplastic Agents / Molecular Targeted Therapy / Transglutaminases / Antineoplastic Agents / Molecular Targeted Therapy / Transglutaminases

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