Antineoplastic Agents

Efficacy of a proapoptotic peptide towards cancer cells

Humans / Mice / Female / Animals / Antimicrobial Cationic Peptides / Amino Acid Sequence / Cell Survival / Antineoplastic Agents / Amino Acid Sequence / Cell Survival / Antineoplastic Agents

LXR-α selectively reprogrammes cancer cells to enter into apoptosis

Cell Cycle / Degenerative Diseases / Apoptosis / Signal Transduction / Nuclear Receptor / RNA interference / Humans / Withanolides / T lymphocytes / Neoplasms / Biological Process / Orphan Nuclear Receptors / Protein Binding / Cell Survival / Antineoplastic Agents / Ligands / Molecular and Cellular Biochemistry / Response Elements / Biochemistry and cell biology / Gene expression profiling / RNA interference / Humans / Withanolides / T lymphocytes / Neoplasms / Biological Process / Orphan Nuclear Receptors / Protein Binding / Cell Survival / Antineoplastic Agents / Ligands / Molecular and Cellular Biochemistry / Response Elements / Biochemistry and cell biology / Gene expression profiling

In vitro and in vivo anti-tumor effects of novel Span 80 vesicles containing immobilized Eucheuma serra agglutinin

Pharmaceutics / Humans / Mice / Female / Animals / Lectins / Drug Delivery Systems / Rhodophyta / Particle Size / Surface Active Agents / Antineoplastic Agents / Lectins / Drug Delivery Systems / Rhodophyta / Particle Size / Surface Active Agents / Antineoplastic Agents

New derivatives of 11-methyl-6-[2-(dimethylamino)ethyl]-6H-indolo[2,3-b]quinoline as cytotoxic DNA topoisomerase II inhibitors

Organic Chemistry / Cell Cycle / Humans / Mice / Animals / Male / Cell Proliferation / Quinolines / Human Fibroblasts / Structure activity Relationship / Antineoplastic Agents / Molecular Structure / Male / Cell Proliferation / Quinolines / Human Fibroblasts / Structure activity Relationship / Antineoplastic Agents / Molecular Structure

Experimental research photodynamic effects in perifocal, oedematous brain tissue

Experimental Research / Photodynamic Therapy / Brain / Blood brain barrier / Animals / Male / Light / Clinical Sciences / Rats / Photochemotherapy / Edema / Necrosis / Wistar Rats / Malignant Glioma / Side Effect / Antineoplastic Agents / Neurosciences / Brain Neoplasms / Chloral Hydrate / Control Group / Male / Light / Clinical Sciences / Rats / Photochemotherapy / Edema / Necrosis / Wistar Rats / Malignant Glioma / Side Effect / Antineoplastic Agents / Neurosciences / Brain Neoplasms / Chloral Hydrate / Control Group

Overexpression of optic atrophy 1 protein increases cisplatin resistance via inactivation of caspase-dependent apoptosis in lung adenocarcinoma cells

Apoptosis / Caspases / Humans / Taiwan / Female / Drug Resistance / Male / Cytochrome C / Clinical Sciences / Cisplatin / Survival Rate / Human Pathology / Antineoplastic Agents / Adenocarcinoma / Drug Resistance / Male / Cytochrome C / Clinical Sciences / Cisplatin / Survival Rate / Human Pathology / Antineoplastic Agents / Adenocarcinoma

ApoE3 mediated polymeric nanoparticles containing curcumin: apoptosis induced in vitro anticancer activity against neuroblastoma cells

Cell Cycle / Nanoparticles / Apoptosis / Pharmaceutics / Humans / Reactive Oxygen Species / Curcumin / Apolipoprotein E / Caspase / Neuroblastoma / Cell Proliferation / Drug Carriers / Cell Survival / Antineoplastic Agents / Ligands / Reactive Oxygen Species / Curcumin / Apolipoprotein E / Caspase / Neuroblastoma / Cell Proliferation / Drug Carriers / Cell Survival / Antineoplastic Agents / Ligands

Hypoxia reduces CD138 expression and induces an immature and stem cell-like transcriptional program in myeloma cells

Oncology / Apoptosis / Cell Differentiation / Tumor microenvironment / Humans / Multiple Myeloma / Peptides / Boronic Acids / Oxygen / Tretinoin / Antineoplastic Agents / Down-Regulation / Multiple Myeloma / Peptides / Boronic Acids / Oxygen / Tretinoin / Antineoplastic Agents / Down-Regulation

3-Amino-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: A new class of CDK2 inhibitors

Organic Chemistry / Enzyme Inhibitors / Macromolecular X-Ray Crystallography / Humans / Bioorganic and medicinal Chemistry / Cell Proliferation / Pyrazoles / Aurora kinases / Structure activity Relationship / Antineoplastic Agents / Molecular Structure / Cell Proliferation / Pyrazoles / Aurora kinases / Structure activity Relationship / Antineoplastic Agents / Molecular Structure

Playing games with a thrombus: a dangerous match. Paradoxical embolism from a huge central venous cathether thrombus: a case report

Cardiovascular / Case Report / Humans / Female / Risk factors / Clinical Sciences / Middle Aged / Cancer Patient / Risk Factors / Central Venous Catheter / Antineoplastic Agents / Adenocarcinoma / Patent Foramen Ovale / Clinical Sciences / Middle Aged / Cancer Patient / Risk Factors / Central Venous Catheter / Antineoplastic Agents / Adenocarcinoma / Patent Foramen Ovale

IMP - GMP specific cytosolic 5\'-nucleotidase regulates nucleotide pool and prodrug metabolism

Biological Sciences / Prodrugs / Humans / Drug Resistance / Physical sciences / Phosphorylation / Substrate Specificity / Cell Survival / Antineoplastic Agents / Nucleotides / Immunoblotting / Phosphorylation / Substrate Specificity / Cell Survival / Antineoplastic Agents / Nucleotides / Immunoblotting

DNA damage responses and oxidative stress in dyskeratosis congenita

Radiation / Oxidative Stress / DNA damage / Apoptosis / Multidisciplinary / Humans / Reactive Oxygen Species / PLoS one / T lymphocytes / Biological markers / Antineoplastic Agents / Gene Expression Regulation / Humans / Reactive Oxygen Species / PLoS one / T lymphocytes / Biological markers / Antineoplastic Agents / Gene Expression Regulation

Cyclotides, a Novel Ultrastable Polypeptide Scaffold for Drug Discovery

Drug Discovery / Macromolecular X-Ray Crystallography / Protein Stability / Genetic Engineering / Humans / Animals / Cyclotides / Protein Conformation / Amino Acid Sequence / Drug Stability / Antineoplastic Agents / Animals / Cyclotides / Protein Conformation / Amino Acid Sequence / Drug Stability / Antineoplastic Agents

Adenylate Kinase 3 Sensitizes Cells to Cigarette Smoke Condensate Vapor Induced Cisplatin Resistance

Tobacco / Apoptosis / Multidisciplinary / Cell line / Bladder Cancer / Cancer Therapy / Risk factors / Smoke / PLoS one / Cisplatin / Adenylate Kinase / Cancer Patient / Risk Factors / Mitochondrial Membrane Potential / Antineoplastic Agents / Cancer Therapy / Risk factors / Smoke / PLoS one / Cisplatin / Adenylate Kinase / Cancer Patient / Risk Factors / Mitochondrial Membrane Potential / Antineoplastic Agents

Brain Metastasis and Response to Ado-Trastuzumab Emtansine: A Case Report and Literature Review

Humans / Female / Adult / Antineoplastic Agents / Brain Neoplasms

Mesoporous silica nanoparticles as a drug delivery system

Technology / Targeted Drug Delivery / Nanoparticles / Drug Delivery System / Stem Cell / Signal Transduction / Biological Sciences / Molecular / Cell line / Humans / Porosity / Mice / Silica / Female / Animals / Drug Delivery Systems / Targeted Therapy / Side Effect / Silicon Dioxide / Antineoplastic Agents / Molecular Targeted Therapy / Clinical Application / Anticancer Drug / Signal Transduction / Biological Sciences / Molecular / Cell line / Humans / Porosity / Mice / Silica / Female / Animals / Drug Delivery Systems / Targeted Therapy / Side Effect / Silicon Dioxide / Antineoplastic Agents / Molecular Targeted Therapy / Clinical Application / Anticancer Drug

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