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Biochemical
Biochemical
Aurora kinase inhibitor ZM447439 induces apoptosis via mitochondrial pathways
Flow Cytometry / Mitochondria / Apoptosis / Colorectal cancer / Humans / Cell Death / Kinase inhibitor / Biochemical / Time Dependent / BIOCHEMICAL PHARMACOLOGY / Aurora kinases / Mitochondrial Membrane Potential / Protein Kinase Inhibitors / Benzamides / Quinazolines / Cell Death / Kinase inhibitor / Biochemical / Time Dependent / BIOCHEMICAL PHARMACOLOGY / Aurora kinases / Mitochondrial Membrane Potential / Protein Kinase Inhibitors / Benzamides / Quinazolines
Vitamin E is a MIF Inhibitor
Enzyme Inhibitors / Humans / Vitamin E / Biochemical / Protein Conformation / Biochemistry and cell biology
Tumor marker nucleoporin 88kDa regulates nucleocytoplasmic transport of NF-κB
Immune response / Mice / Animals / Nuclear pore complex / Biochemical / Transcription Factor / Cell nucleus / Cytoplasm / Biochemistry and cell biology / Transcription Factor / Cell nucleus / Cytoplasm / Biochemistry and cell biology
Assembling amyloid fibrils from designed structures containing a significant amyloid beta-peptide fragment
Electron Microscopy / Biological Sciences / Humans / Circular Dichroism / Biochemical / Amyloid Beta / CHEMICAL SCIENCES / Protein Secondary Structure Prediction / Protein Conformation / Amino Acid Sequence / Alzheimer Disease / Dimerization / Amyloid Beta / CHEMICAL SCIENCES / Protein Secondary Structure Prediction / Protein Conformation / Amino Acid Sequence / Alzheimer Disease / Dimerization
A new fluorescent probe for the equilibrative inhibitor-sensitive nucleoside transporter. 5\'-S-(2-aminoethyl)-N6-(4-nitrobenzyl)-5\'-thioadenosine (SAENTA)-chi 2-fluorescein
Biological Sciences / Biochemical / CHEMICAL SCIENCES
The ascorbic acid paradox
Antioxidants / Humans / Tissue culture / Reactive Oxygen Species / Biochemical / Differentiation / Antioxidant Activity / Ascorbic Acid / Dietary Supplement / Culture Media / Biochemistry and cell biology / Differentiation / Antioxidant Activity / Ascorbic Acid / Dietary Supplement / Culture Media / Biochemistry and cell biology
The Bacteriophage T7 Binary System Activates Transient Transgene Expression in Zebrafish (Danio rerio) Embryos
Danio rerio / Escherichia coli / Animals / Cytomegalovirus / Biochemical / Plasmids / Zebrafish / Embryos / Transgene Expression / Biochemistry and cell biology / Plasmids / Zebrafish / Embryos / Transgene Expression / Biochemistry and cell biology
OCTN3 is a mammalian peroxisomal membrane carnitine transporter
Membrane Proteins / Humans / Liver / Mice / Animals / Male / Catalase / Biochemical / Lipid metabolism / Enzyme / L-carnitine / Western blot / Fatty Acid / Peroxisomes / Rabbits / Membrane Protein / Biochemistry and cell biology / Male / Catalase / Biochemical / Lipid metabolism / Enzyme / L-carnitine / Western blot / Fatty Acid / Peroxisomes / Rabbits / Membrane Protein / Biochemistry and cell biology
CoA and fatty acyl-CoA derivatives mobilize calcium from a liver reticular pool
Kinetics / Calcium / Biological Sciences / Liver / Animals / Endoplasmic Reticulum / Biochemical / Esterification / CHEMICAL SCIENCES / Rats / Adenosine Triphosphate / Endoplasmic Reticulum / Biochemical / Esterification / CHEMICAL SCIENCES / Rats / Adenosine Triphosphate
The Bacteriophage T7 Binary System Activates Transient Transgene Expression in Zebrafish (Danio rerio) Embryos
Danio rerio / Escherichia coli / Animals / Cytomegalovirus / Biochemical / Plasmids / Zebrafish / Embryos / Transgene Expression / Biochemistry and cell biology / Plasmids / Zebrafish / Embryos / Transgene Expression / Biochemistry and cell biology
A multi-metabolite analysis of serum by 1H NMR spectroscopy: Early systemic signs of Alzheimer’s disease
Metabolomics / Mild Cognitive Impairment / NMR Spectroscopy / Metabolic syndrome / Humans / P-glycoprotein / Biochemical / Glycoproteins / Lipoprotein(a) / Lipoproteins / Fatty Acid / SERUM / Cognitive Decline / Memory Disorders / Alzheimer Disease / Early Diagnosis / Lipoprotein a / Low molecular weight / Biochemistry and cell biology / P-glycoprotein / Biochemical / Glycoproteins / Lipoprotein(a) / Lipoproteins / Fatty Acid / SERUM / Cognitive Decline / Memory Disorders / Alzheimer Disease / Early Diagnosis / Lipoprotein a / Low molecular weight / Biochemistry and cell biology
5′-S-(2-Aminoethyl)-N6-(4-nitrobenzyl)-5′-thioadenosine (SAENTA), a novel ligand with high affinity for polypeptides associated with nucleoside transporter
Biological Sciences / Biochemical / CHEMICAL SCIENCES
Aurora kinase inhibitor ZM447439 induces apoptosis via mitochondrial pathways
Flow Cytometry / Mitochondria / Apoptosis / Colorectal cancer / Humans / Cell Death / Kinase inhibitor / Biochemical / Time Dependent / BIOCHEMICAL PHARMACOLOGY / Aurora kinases / Mitochondrial Membrane Potential / Protein Kinase Inhibitors / Benzamides / Quinazolines / Cell Death / Kinase inhibitor / Biochemical / Time Dependent / BIOCHEMICAL PHARMACOLOGY / Aurora kinases / Mitochondrial Membrane Potential / Protein Kinase Inhibitors / Benzamides / Quinazolines
Characterization of HSCD5, a novel human stearoyl-CoA desaturase unique to primates
Molecular Evolution / Gene expression / Energy Metabolism / Real-time RT-PCR / DNA / Primates / Phylogeny / Humans / Animals / Endoplasmic Reticulum / Biochemical / Molecular cloning / Amino Acid Sequence / Base Sequence / Monounsaturated Fatty Acid / Membrane Protein / Subcellular Fractions / Recombinant Proteins / Biochemistry and cell biology / Stearoyl-CoA desaturase / Primates / Phylogeny / Humans / Animals / Endoplasmic Reticulum / Biochemical / Molecular cloning / Amino Acid Sequence / Base Sequence / Monounsaturated Fatty Acid / Membrane Protein / Subcellular Fractions / Recombinant Proteins / Biochemistry and cell biology / Stearoyl-CoA desaturase
Plasmodium falciparum signal peptide peptidase is a promising drug target against blood stage malaria
Gene Silencing / Humans / Animals / Drug Design / Biochemical / Protease Inhibitors / Presenilins / Plasmodium falciparum / Antimalarials / Protein Conformation / Amino Acid Sequence / Erythrocytes / Drug Targeting / Carbamates / Biochemistry and cell biology / Protease Inhibitors / Presenilins / Plasmodium falciparum / Antimalarials / Protein Conformation / Amino Acid Sequence / Erythrocytes / Drug Targeting / Carbamates / Biochemistry and cell biology
C-Npys (S-3-nitro-2-pyridinesulfenyl) and peptide derivatives can inhibit a serine-thiol proteinase activity from Paracoccidioides brasiliensis
Fluorescence Resonance Energy Transfer / Peptides / Biochemical / Affinity chromatography / Fungal Pathogens / Pyridines / Cysteine endopeptidases / Serine Protease / Therapeutic Use / Paracoccidioides / Biochemistry and cell biology / Molecular Structure / Cysteine Proteinase Inhibitors / Pyridines / Cysteine endopeptidases / Serine Protease / Therapeutic Use / Paracoccidioides / Biochemistry and cell biology / Molecular Structure / Cysteine Proteinase Inhibitors
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