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Biological activity
Biological activity
Indole-2-carboxamides as novel NR2B selective NMDA receptor antagonists
Organic Chemistry / Magnetic Resonance Spectroscopy / Phenols / Radioligand Assay / Bioorganic and medicinal Chemistry / Biological activity / Structure activity Relationship / Piperidines / Biological activity / Structure activity Relationship / Piperidines
Benzimidazole-2-carboxamides as novel NR2B selective NMDA receptor antagonists
Organic Chemistry / Amides / Bioorganic and medicinal Chemistry / Biological activity / Benzimidazoles / Structure activity Relationship / Molecular Structure / Formalin Test / Structure activity Relationship / Molecular Structure / Formalin Test
Bioactive natural peptides
NMR Spectroscopy / Enzymatic hydrolysis / Antimicrobial Peptide / Single Cell / Mode of action / Amino Acid Profile / Large Scale / Biological activity / Amino Acid Sequence / Antitumor Activity / Lipid Bilayer / Amino Acid Profile / Large Scale / Biological activity / Amino Acid Sequence / Antitumor Activity / Lipid Bilayer
Recombinant Environmental Libraries Provide Access to Microbial Diversity for Drug Discovery from Natural Products
Genetics / Drug Discovery / Microbial diversity / Multidisciplinary / Streptomyces / Escherichia coli / Applied / Applied Environmental Microbiology / Natural Product / Bacteria / Polymerase Chain Reaction / Soil Microbiology / High Pressure Liquid Chromatography / Molecular cloning / Anti-Bacterial Agents / Liquid Chromatography / Multienzyme complexes / Genetic Recombination / Genetic variation / Microbial Diversity / Biological activity / Amino Acid Sequence / Escherichia coli / Applied / Applied Environmental Microbiology / Natural Product / Bacteria / Polymerase Chain Reaction / Soil Microbiology / High Pressure Liquid Chromatography / Molecular cloning / Anti-Bacterial Agents / Liquid Chromatography / Multienzyme complexes / Genetic Recombination / Genetic variation / Microbial Diversity / Biological activity / Amino Acid Sequence
Bioactive phenolic glycosides from Amburana cearensis
Phytochemistry / Biological Sciences / CHEMICAL SCIENCES / Antibacterial activity / Biological activity
SiRNA-loaded multi-shell nanoparticles incorporated into a multilayered film as a reservoir for gene silencing
Biomaterials / Tissue Engineering / Scanning Electron Microscopy / Nanoparticles / Atomic Force Microscopy / Multidisciplinary / Gene Silencing / Humans / Surface modification / Osteocalcin / Osteopontin / Calcium Phosphate / Model System / Bone Formation / Biological activity / Osteoblasts / Multidisciplinary / Gene Silencing / Humans / Surface modification / Osteocalcin / Osteopontin / Calcium Phosphate / Model System / Bone Formation / Biological activity / Osteoblasts
SiRNA-loaded multi-shell nanoparticles incorporated into a multilayered film as a reservoir for gene silencing
Biomaterials / Tissue Engineering / Scanning Electron Microscopy / Nanoparticles / Atomic Force Microscopy / Multidisciplinary / Gene Silencing / Humans / Surface modification / Osteocalcin / Osteopontin / Calcium Phosphate / Model System / Bone Formation / Biological activity / Osteoblasts / Multidisciplinary / Gene Silencing / Humans / Surface modification / Osteocalcin / Osteopontin / Calcium Phosphate / Model System / Bone Formation / Biological activity / Osteoblasts
Cell specific, cross-species expression of myrosinases in Brassica napus, Arabidopsis thaliana and Nicotiana tabacum
Genetics / Plant Biology / Tobacco / Immunohistochemistry / Plant Molecular Biology / In Situ Hybridization / Arabidopsis thaliana / Plants / Glucuronidase / Arabidopsis / Enzyme / Nicotiana Tabacum / Brassica Napus / Seeds / Substrate Specificity / Plant Stem Cells / SIGNAL PEPTIDE / Biological activity / Biochemistry and cell biology / In Situ Hybridization / Arabidopsis thaliana / Plants / Glucuronidase / Arabidopsis / Enzyme / Nicotiana Tabacum / Brassica Napus / Seeds / Substrate Specificity / Plant Stem Cells / SIGNAL PEPTIDE / Biological activity / Biochemistry and cell biology
Bioactive apocarotenoids from Tectona grandis
Phytochemistry / Nuclear Magnetic Resonance / Carotenoids / Biological Sciences / Lamiaceae / Allium Cepa / Natural Product / CHEMICAL SCIENCES / Tectona Grandis / Capsicum / Lactuca Sativa / Solanum Melongena / Biological activity / Triticum / Biological Assay / Chemical Structure / Lycopersicon esculentum / Allium Cepa / Natural Product / CHEMICAL SCIENCES / Tectona Grandis / Capsicum / Lactuca Sativa / Solanum Melongena / Biological activity / Triticum / Biological Assay / Chemical Structure / Lycopersicon esculentum
Three structurally related, highly potent, peptides from the venom of Parabuthus transvaalicus possess divergent biological activity
South Africa / Nomenclature / Sequence alignment / Mice / Animals / Insects / Peptides / Rat Brain / SCORPIONS / Neurotoxins / High Pressure Liquid Chromatography / South African / Protein Sequence Analysis / Rats / SYNAPTOSOMES / Nervous System / Protein Conformation / Biological activity / Species Specificity / Amino Acid Sequence / Protein Binding / Toxicon / Cumulant / Motor activity / Insects / Peptides / Rat Brain / SCORPIONS / Neurotoxins / High Pressure Liquid Chromatography / South African / Protein Sequence Analysis / Rats / SYNAPTOSOMES / Nervous System / Protein Conformation / Biological activity / Species Specificity / Amino Acid Sequence / Protein Binding / Toxicon / Cumulant / Motor activity
Transgenic sugarcane plants resistant to stem borer attack
Plant Biology / Molecular Breeding / Molecular / Plant Resistance / Bacillus thuringiensis / Genetic transformation / Biological activity / Transgenic plant / Genetic transformation / Biological activity / Transgenic plant
Cardenolide Glycosides from Pergularia tomentosa and Their Proapoptotic Activity in Kaposi\'s Sarcoma Cells
Natural Products / Egypt / Pharmacognosy / Medicinal Plants / Cytotoxicity / Apoptosis / Structural Analysis / Biological Sciences / Cell line / Humans / ROOT / Cell Death / Plant Roots / CHEMICAL SCIENCES / Apoptose / Isolation / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Natural / Asclepiadaceae / Biological activity / Glycosides / Apoptosis / Structural Analysis / Biological Sciences / Cell line / Humans / ROOT / Cell Death / Plant Roots / CHEMICAL SCIENCES / Apoptose / Isolation / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Natural / Asclepiadaceae / Biological activity / Glycosides
Placental immunomodulator ferritin, a novel immunoregulator, suppresses experimental arthritis
Immunology / Treatment / Cytokines / Histology / Spleen / Mice / Female / Animals / Animal Model / Arthritis / Clinical Sciences / Rats / Public health systems and services research / Rat / Joints / Biological activity / Lymphocytes / Enzyme Linked Immunosorbent Assay / Mice / Female / Animals / Animal Model / Arthritis / Clinical Sciences / Rats / Public health systems and services research / Rat / Joints / Biological activity / Lymphocytes / Enzyme Linked Immunosorbent Assay
Recombinant Environmental Libraries Provide Access to Microbial Diversity for Drug Discovery from Natural Products
Genetics / Drug Discovery / Microbial diversity / Multidisciplinary / Streptomyces / Escherichia coli / Applied / Applied Environmental Microbiology / Natural Product / Bacteria / Polymerase Chain Reaction / Soil Microbiology / High Pressure Liquid Chromatography / Molecular cloning / Anti-Bacterial Agents / Liquid Chromatography / Multienzyme complexes / Genetic Recombination / Genetic variation / Microbial Diversity / Biological activity / Amino Acid Sequence / Escherichia coli / Applied / Applied Environmental Microbiology / Natural Product / Bacteria / Polymerase Chain Reaction / Soil Microbiology / High Pressure Liquid Chromatography / Molecular cloning / Anti-Bacterial Agents / Liquid Chromatography / Multienzyme complexes / Genetic Recombination / Genetic variation / Microbial Diversity / Biological activity / Amino Acid Sequence
Sexual dimorphism in venom of Bothrops jararaca(Serpentes: Viperidae)
Skeletal muscle biology / Sexual dimorphism / Growth / Mice / Female / Animals / Male / Body Size / Niche Partitioning / Rats / Bothrops / Wistar Rats / Biological activity / Toxicon / Growth Curve / Animals / Male / Body Size / Niche Partitioning / Rats / Bothrops / Wistar Rats / Biological activity / Toxicon / Growth Curve
Synthesis and Biological Activity of Aromatic Amino Acid Phosphoramidates of 5-Fluoro-2‘-deoxyuridine and 1-β-Arabinofuranosylcytosine: Evidence of Phosphoramidase Activity
Organic Chemistry / Medicinal Chemistry / Magnetic Resonance Spectroscopy / Cell Division / Cell line / Humans / Mice / Animals / Aromatic amino acid / Organophosphorus Compounds / Biological activity / Humans / Mice / Animals / Aromatic amino acid / Organophosphorus Compounds / Biological activity
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