Caspases

Baicalin induces apoptosis via mitochondrial pathway as prooxidant

Immunology / Mitochondria / Flavonoids / Apoptosis / Herbal Medicine / Caspases / Molecular Immunology / Humans / Reactive Oxygen Species / Cytochrome C / Glutathione / Caspase / T lymphocytes / chronic hepatitis C / Peripheral Blood Mononuclear Cells / Caspases / Molecular Immunology / Humans / Reactive Oxygen Species / Cytochrome C / Glutathione / Caspase / T lymphocytes / chronic hepatitis C / Peripheral Blood Mononuclear Cells

Novel acylated steroidal glycosides from Caralluma tuberculata induce caspase-dependent apoptosis in cancer cells

Complementary and Alternative Medicine / Chromatography / Plant Biology / Mass Spectrometry / Breast Cancer / Ethnopharmacology / Medicinal Plants / Magnetic Resonance Spectroscopy / Apoptosis / Western blotting / Caspases / Humans / Lancet / Caco-2 cells / Neoplasms / Asclepiadaceae / Acylation / Cell Proliferation / Structure activity Relationship / Structural Similarity Index / Cell Survival / Glycosides / Molecular Structure / Cysteine Proteinase Inhibitors / MTT assay / Ethnopharmacology / Medicinal Plants / Magnetic Resonance Spectroscopy / Apoptosis / Western blotting / Caspases / Humans / Lancet / Caco-2 cells / Neoplasms / Asclepiadaceae / Acylation / Cell Proliferation / Structure activity Relationship / Structural Similarity Index / Cell Survival / Glycosides / Molecular Structure / Cysteine Proteinase Inhibitors / MTT assay

Nitric Oxide Induces Osteoblast Apoptosis through a Mitochondria-Dependent Pathway

Mitochondria / Apoptosis / Multidisciplinary / Caspases / Reactive Oxygen Species / Nitric oxide / Animals / Cytochrome C / Cell Viability / Alkaline phosphatase / Caspase / Mitochondrial dysfunction / alkaline phosphatase activity (APA) / Rats / Time Dependent / Wistar Rats / Bone remodeling / Osteoblasts / Mitochondrial Membrane Potential / Sodium Nitroprusside / Experimental Model / Nitric oxide / Animals / Cytochrome C / Cell Viability / Alkaline phosphatase / Caspase / Mitochondrial dysfunction / alkaline phosphatase activity (APA) / Rats / Time Dependent / Wistar Rats / Bone remodeling / Osteoblasts / Mitochondrial Membrane Potential / Sodium Nitroprusside / Experimental Model

Diazene JK-279 induces apoptosis-like cell death in human cervical carcinoma cells

Flow Cytometry / Cell Cycle / Apoptosis / Molecular Mechanics / Caspases / Humans / Cancer Therapy / Drug Resistance / Cell Death / Glutathione / Caspase / Cell nucleus / HeLa cells / Pyridines / In Vitro Toxicology / Cell Survival / Antineoplastic Agents / Humans / Cancer Therapy / Drug Resistance / Cell Death / Glutathione / Caspase / Cell nucleus / HeLa cells / Pyridines / In Vitro Toxicology / Cell Survival / Antineoplastic Agents

Novel dimeric Smac analogs as prospective anticancer agents

Organic Chemistry / Caspases / Humans / Mice / Female / Animals / Cell Survival / Antineoplastic Agents / Dimerization / Animals / Cell Survival / Antineoplastic Agents / Dimerization

GDNF-deprived sympathetic neurons die via a novel nonmitochondrial pathway

Cell Biology / Mitochondria / Biological Sciences / Caspases / Humans / Animals / Cell Death / Cytochrome C / Glial Cell / Proteins / Neurons / Rats / The cell / Sympathetic Nervous System / Nerve Growth Factor / Cell Survival / Animals / Cell Death / Cytochrome C / Glial Cell / Proteins / Neurons / Rats / The cell / Sympathetic Nervous System / Nerve Growth Factor / Cell Survival

DNA Damage and Activated Caspase-3 Expression in Neurons and Astrocytes: Evidence for Apoptosis in Frontotemporal Dementia

Psychology / Dementia / DNA damage / Apoptosis / Neuronal cell death / Caspases / Temporal Lobe / Brain / Humans / Female / Male / Astrocyte / Neurons / Astrocytes / Temporal Cortex / Clinical Sciences / Caspase / Aged / Middle Aged / Cell nucleus / Experimental / Frontotemporal Dementia / Degeneration / Glial Fibrillary Acidic Protein / Neurodegenerative Disease / Experimental Neurology / Sperm Dna Fragmentation / Neurosciences / Frontal Lobe / Behavioral symptoms / Gliosis / Caspases / Temporal Lobe / Brain / Humans / Female / Male / Astrocyte / Neurons / Astrocytes / Temporal Cortex / Clinical Sciences / Caspase / Aged / Middle Aged / Cell nucleus / Experimental / Frontotemporal Dementia / Degeneration / Glial Fibrillary Acidic Protein / Neurodegenerative Disease / Experimental Neurology / Sperm Dna Fragmentation / Neurosciences / Frontal Lobe / Behavioral symptoms / Gliosis

Koetjapic acid, a natural triterpenoid, induces apoptosis in colon cancer cells

Apoptosis / Signal Transduction / Caspases / Cell line / Humans / Meliaceae / Cell nucleus / Plant extracts / Cell Proliferation / Sperm Dna Fragmentation / Triterpenes / Meliaceae / Cell nucleus / Plant extracts / Cell Proliferation / Sperm Dna Fragmentation / Triterpenes

Overexpression of optic atrophy 1 protein increases cisplatin resistance via inactivation of caspase-dependent apoptosis in lung adenocarcinoma cells

Apoptosis / Caspases / Humans / Taiwan / Female / Drug Resistance / Male / Cytochrome C / Clinical Sciences / Cisplatin / Survival Rate / Human Pathology / Antineoplastic Agents / Adenocarcinoma / Drug Resistance / Male / Cytochrome C / Clinical Sciences / Cisplatin / Survival Rate / Human Pathology / Antineoplastic Agents / Adenocarcinoma

Death to flies: Drosophila as a model system to study programmed cell death

Genetics / Immunology / Drosophila melanogaster / Apoptosis / Caspases / Drosophila / Animals / Cell Death / Programmed cell death / Proteins / Behavioral Animal Models / Optometry and Ophthalmology / Model System / Apoptotic Protease Activating Factor-1 / Drosophila / Animals / Cell Death / Programmed cell death / Proteins / Behavioral Animal Models / Optometry and Ophthalmology / Model System / Apoptotic Protease Activating Factor-1

5′-aminoimidazole-4-carboxamide riboside induces apoptosis in human neuroblastoma cells

Neuroscience / Psychology / Enzyme Inhibitors / Apoptosis / Caspases / Cell line / Cell Differentiation / Brain / Humans / Acetylcholine / Neurons / Enzyme / Norepinephrine / Caspase / Neuroblastoma / Retinoic Acid / Tretinoin / Protein Kinase / Bovine Serum Albumin / Neurosciences / Phorbol ester / Cell line / Cell Differentiation / Brain / Humans / Acetylcholine / Neurons / Enzyme / Norepinephrine / Caspase / Neuroblastoma / Retinoic Acid / Tretinoin / Protein Kinase / Bovine Serum Albumin / Neurosciences / Phorbol ester

TRAIL/Apo-2 Ligand Induces Primary Plasma Cell Apoptosis

Immunology / Immunology of the Gut / Apoptosis / Caspases / Cell Differentiation / Humans / Mice / Animals / NF-kappa B / The / T cells / Tumor necrosis factor-alpha / Ligands / Interleukin / Down-Regulation / Humans / Mice / Animals / NF-kappa B / The / T cells / Tumor necrosis factor-alpha / Ligands / Interleukin / Down-Regulation

Triptolide sensitizes resistant cholangiocarcinoma cells to TRAIL-induced apoptosis

Apoptosis / Caspases / Humans / Resistance / Cell Death / Mitogen Activated Protein Kinase / Trail / Caspase / Anticancer / Apoptose / Cholangiocarcinoma / Diterpenes / Tumor necrosis factor-alpha / Down-Regulation / Mitogen Activated Protein Kinase / Trail / Caspase / Anticancer / Apoptose / Cholangiocarcinoma / Diterpenes / Tumor necrosis factor-alpha / Down-Regulation

Reactive oxygen species is essential for cycloheximide to sensitize lexatumumab-induced apoptosis in hepatocellular carcinoma cells

Drug interactions / Apoptosis / Multidisciplinary / Caspases / Cell line / Humans / Reactive Oxygen Species / Hepatocellular Carcinoma / Cell Death / Cytochrome C / Monoclonal Antibodies / PLoS one / Conformational Change / Intracellular Space / Cycloheximide / Humans / Reactive Oxygen Species / Hepatocellular Carcinoma / Cell Death / Cytochrome C / Monoclonal Antibodies / PLoS one / Conformational Change / Intracellular Space / Cycloheximide

Establishment of a Cell-Free System of Neuronal Apoptosis: Comparison of Premitochondrial, Mitochondrial, and Postmitochondrial Phases

Enzyme Inhibitors / Mitochondria / Apoptosis / Neuronal cell death / Caspases / Cerebellum / Animals / Cytochrome C / Peptides / The / Neurons / Caspase / Tamoxifen / Rats / Cysteine endopeptidases / Nervous System / Cell free System / Staurosporine / Adenosine Triphosphate / DNA fragmentation / Cerebellum / Animals / Cytochrome C / Peptides / The / Neurons / Caspase / Tamoxifen / Rats / Cysteine endopeptidases / Nervous System / Cell free System / Staurosporine / Adenosine Triphosphate / DNA fragmentation

DCP-1, a Drosophila Cell Death Protease Essential for Development

Science / Apoptosis / Multidisciplinary / Caspases / Drosophila / Humans / Mutation / Animals / Cell Death / Molecular cloning / HeLa cells / Cysteine endopeptidases / Amino Acid Sequence / DNA fragmentation / Humans / Mutation / Animals / Cell Death / Molecular cloning / HeLa cells / Cysteine endopeptidases / Amino Acid Sequence / DNA fragmentation
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