Caspases

3-O-[N-(p-fluorobenzenesulfonyl)-carbamoyl]-oleanolic acid, a semisynthetic analog of oleanolic acid, induces apoptosis in breast cancer cells

Apoptosis / Caspases / Humans / Female / Caspase / Cell Proliferation / Cell Survival / Antineoplastic Agents / Oleanolic acid / Estrogen receptor alpha / Fas Ligand / Cell Proliferation / Cell Survival / Antineoplastic Agents / Oleanolic acid / Estrogen receptor alpha / Fas Ligand

Testosterone promotes apoptotic damage in human renal tubular cells

Nephrology / Urology / Dialysis / Apoptosis / Caspases / Cell line / Humans / Testosterone / Kidney / End Stage Renal Disease / Cell Death / Androgens / Morphological Analysis / Clinical Sciences / Caspase / Western blot / Androgen Receptor / Chronic Renal Disease / Primary Culture / Level / Proximal Tubule / Cell Survival / Propidium Iodide / Terminal Deoxynucleotidyl Transferase / Fas Ligand / Cell line / Humans / Testosterone / Kidney / End Stage Renal Disease / Cell Death / Androgens / Morphological Analysis / Clinical Sciences / Caspase / Western blot / Androgen Receptor / Chronic Renal Disease / Primary Culture / Level / Proximal Tubule / Cell Survival / Propidium Iodide / Terminal Deoxynucleotidyl Transferase / Fas Ligand

5′-AMINOIMIDAZOLE-4-CARBOXAMIDE Riboside Induces Apoptosis in Human Neuroblastoma Cells

Neuroscience / Psychology / Enzyme Inhibitors / Apoptosis / Caspases / Cell line / Cell Differentiation / Brain / Humans / Acetylcholine / Neurons / Differentiation / Enzyme / Norepinephrine / Caspase / Neuroblastoma / PBS / Retinoic Acid / Tretinoin / Protein Kinase / Bovine Serum Albumin / Neurosciences / Phorbol ester / Serum albumin / Cell line / Cell Differentiation / Brain / Humans / Acetylcholine / Neurons / Differentiation / Enzyme / Norepinephrine / Caspase / Neuroblastoma / PBS / Retinoic Acid / Tretinoin / Protein Kinase / Bovine Serum Albumin / Neurosciences / Phorbol ester / Serum albumin

Drug-resistant breast carcinoma (MCF-7) cells are paradoxically sensitive to apoptosis

Enzyme Inhibitors / Mitochondria / Apoptosis / Western blotting / Caspases / Cellular / Humans / Female / Drug Resistance / Cellular Physiology / Medical Physiology / Caspase / Doxorubicin / Carcinoma / Breast carcinoma / Staurosporine / Cellular / Humans / Female / Drug Resistance / Cellular Physiology / Medical Physiology / Caspase / Doxorubicin / Carcinoma / Breast carcinoma / Staurosporine

Administration of Human Protein-C concentrate prevents apoptotic brain cell death after experimental sepsis

Cognitive Science / Flow Cytometry / Immunohistochemistry / Apoptosis / Caspases / Brain / Animals / Male / Cell Death / Cytochrome C / Sepsis / Astrocyte / Rat Brain / Cytoprotection / Neurons / Astrocytes / Apoptose / Rats / Time Dependent / Endothelial cell / Time Factors / Wistar Rats / Neurosciences / Cecal ligation and puncture / Brain / Animals / Male / Cell Death / Cytochrome C / Sepsis / Astrocyte / Rat Brain / Cytoprotection / Neurons / Astrocytes / Apoptose / Rats / Time Dependent / Endothelial cell / Time Factors / Wistar Rats / Neurosciences / Cecal ligation and puncture

Nitric Oxide Induces Osteoblast Apoptosis through a Mitochondria-Dependent Pathway

Mitochondria / Apoptosis / Multidisciplinary / Caspases / Reactive Oxygen Species / Nitric oxide / Animals / Cytochrome C / Cell Viability / Alkaline phosphatase / Caspase / Mitochondrial dysfunction / alkaline phosphatase activity (APA) / Rats / Time Dependent / Wistar Rats / Bone remodeling / Osteoblasts / Mitochondrial Membrane Potential / Sodium Nitroprusside / Experimental Model / Nitric oxide / Animals / Cytochrome C / Cell Viability / Alkaline phosphatase / Caspase / Mitochondrial dysfunction / alkaline phosphatase activity (APA) / Rats / Time Dependent / Wistar Rats / Bone remodeling / Osteoblasts / Mitochondrial Membrane Potential / Sodium Nitroprusside / Experimental Model

Soluble Semicarbazide Sensitive Amine Oxidase (SSAO) catalysis induces apoptosis in vascular smooth muscle cells

Catalysis / Medical Microbiology / Immunohistochemistry / Apoptosis / Western blotting / Biological Sciences / Caspases / Humans / Smooth muscle / Cytochrome C / Physical sciences / Solubility / Caspase / Hydrogen Peroxide / Substrate Specificity / Formaldehyde / Cell Survival / Blood Vessel / Oxidation-Reduction / Oxidants / Biochemistry and cell biology / Blood Plasma / Biological Sciences / Caspases / Humans / Smooth muscle / Cytochrome C / Physical sciences / Solubility / Caspase / Hydrogen Peroxide / Substrate Specificity / Formaldehyde / Cell Survival / Blood Vessel / Oxidation-Reduction / Oxidants / Biochemistry and cell biology / Blood Plasma

Triptolide sensitizes resistant cholangiocarcinoma cells to TRAIL-induced apoptosis

Apoptosis / Caspases / Humans / Resistance / Cell Death / Mitogen Activated Protein Kinase / Trail / Caspase / Anticancer / Apoptose / Cholangiocarcinoma / Diterpenes / Tumor necrosis factor-alpha / Down-Regulation / Mitogen Activated Protein Kinase / Trail / Caspase / Anticancer / Apoptose / Cholangiocarcinoma / Diterpenes / Tumor necrosis factor-alpha / Down-Regulation

Novel dimeric Smac analogs as prospective anticancer agents

Organic Chemistry / Apoptosis / Caspases / Humans / Mice / Female / Animals / Cell Survival / Antineoplastic Agents / Dimerization / Female / Animals / Cell Survival / Antineoplastic Agents / Dimerization

Methamphetamine induces neuronal apoptosis via cross-talks between endoplasmic reticulum and mitochondria-dependent death cascades

Physiology / Mitochondria / Apoptosis / Signal Transduction / Molecular chaperones / Caspases / Mice / Animals / Methamphetamine / Male / Cell Death / Cytochrome C / Endoplasmic Reticulum / ER stress / Medical Physiology / Neurons / Transcription Factor / Calpain / Illicit Drugs / Heat Shock Proteins / Gamma-Aminobutyric Acid / Biochemistry and cell biology / DNA fragmentation / Neuronal apoptosis / Caspases / Mice / Animals / Methamphetamine / Male / Cell Death / Cytochrome C / Endoplasmic Reticulum / ER stress / Medical Physiology / Neurons / Transcription Factor / Calpain / Illicit Drugs / Heat Shock Proteins / Gamma-Aminobutyric Acid / Biochemistry and cell biology / DNA fragmentation / Neuronal apoptosis

Granzyme B of cytotoxic T cells induces extramitochondrial reactive oxygen species production via caspase-dependent NADPH oxidase activation

Immunology / Immune response / Cell Biology / Mitochondria / Apoptosis / Signal Transduction / Caspases / Cell line / Allergy / Mitochondrial DNA / Humans / Reactive Oxygen Species / Mice / Animals / Cell Death / Cytochrome C / NADPH oxidase / Immunology & Cell Biology / Oxidative phosphorylation / Mitochondrial Membrane Potential / Conformational Change / Biochemistry and cell biology / Cytotoxic T cells / Immunoblotting / Signal Transduction / Caspases / Cell line / Allergy / Mitochondrial DNA / Humans / Reactive Oxygen Species / Mice / Animals / Cell Death / Cytochrome C / NADPH oxidase / Immunology & Cell Biology / Oxidative phosphorylation / Mitochondrial Membrane Potential / Conformational Change / Biochemistry and cell biology / Cytotoxic T cells / Immunoblotting

Bacterial redox protein azurin induce apoptosis in human osteosarcoma U2OS cells

Fluorescence Microscopy / Transmission Electron Microscopy / Apoptosis / Caspases / Humans / Osteosarcoma / Bcl / Pseudomonas aeruginosa / Caspase / Pharmacological / Pseudomonas Aeruginosa / Cell Proliferation / Cell Cycle Arrest / Low molecular weight / Pathogenic Bacteria / DNA fragmentation / Bacterial Production / Osteosarcoma / Bcl / Pseudomonas aeruginosa / Caspase / Pharmacological / Pseudomonas Aeruginosa / Cell Proliferation / Cell Cycle Arrest / Low molecular weight / Pathogenic Bacteria / DNA fragmentation / Bacterial Production

DNA Damage and Activated Caspase-3 Expression in Neurons and Astrocytes: Evidence for Apoptosis in Frontotemporal Dementia

Psychology / Dementia / DNA damage / Apoptosis / Neuronal cell death / Caspases / Temporal Lobe / Brain / Humans / Female / Male / Astrocyte / Neurons / Astrocytes / Temporal Cortex / Clinical Sciences / Caspase / Aged / Middle Aged / Cell nucleus / Experimental / Frontotemporal Dementia / Degeneration / Glial Fibrillary Acidic Protein / Neurodegenerative Disease / Experimental Neurology / Sperm Dna Fragmentation / Neurosciences / Frontal Lobe / Behavioral symptoms / Gliosis / DNA fragmentation / Caspases / Temporal Lobe / Brain / Humans / Female / Male / Astrocyte / Neurons / Astrocytes / Temporal Cortex / Clinical Sciences / Caspase / Aged / Middle Aged / Cell nucleus / Experimental / Frontotemporal Dementia / Degeneration / Glial Fibrillary Acidic Protein / Neurodegenerative Disease / Experimental Neurology / Sperm Dna Fragmentation / Neurosciences / Frontal Lobe / Behavioral symptoms / Gliosis / DNA fragmentation

Novel acylated steroidal glycosides from Caralluma tuberculata induce caspase-dependent apoptosis in cancer cells

Complementary and Alternative Medicine / Chromatography / Plant Biology / Mass Spectrometry / Breast Cancer / Ethnopharmacology / Medicinal Plants / Magnetic Resonance Spectroscopy / Apoptosis / Western blotting / Caspases / Humans / Lancet / Caco-2 cells / Neoplasms / Asclepiadaceae / Acylation / Cell Proliferation / Structure activity Relationship / Structural Similarity Index / Cell Survival / Glycosides / Molecular Structure / Cysteine Proteinase Inhibitors / MTT assay / Neutral Red / Ethnopharmacology / Medicinal Plants / Magnetic Resonance Spectroscopy / Apoptosis / Western blotting / Caspases / Humans / Lancet / Caco-2 cells / Neoplasms / Asclepiadaceae / Acylation / Cell Proliferation / Structure activity Relationship / Structural Similarity Index / Cell Survival / Glycosides / Molecular Structure / Cysteine Proteinase Inhibitors / MTT assay / Neutral Red

Novel Drug Amooranin Induces Apoptosis Through Caspase Activity in Human Breast Carcinoma Cell Lines

Breast Cancer / Apoptosis / Caspases / Tropical trees / Cell line / Humans / Breast Cancer Early Detecion and Treatment / Multidrug Resistance / Female / Cell Death / Caspase / Plant extracts / Carcinoma / Breast carcinoma / Triterpenes / Enzyme Induction / Humans / Breast Cancer Early Detecion and Treatment / Multidrug Resistance / Female / Cell Death / Caspase / Plant extracts / Carcinoma / Breast carcinoma / Triterpenes / Enzyme Induction

Mitochondria and cell death. Mechanistic aspects and methodological issues

Fluorescence / Calcium / Membrane Proteins / Mitochondria / Apoptosis / Caspases / Humans / Permeability / Animals / Cell Death / Cytochrome C / European / Necrosis / Ion Transport / Biochemistry and cell biology / Caspases / Humans / Permeability / Animals / Cell Death / Cytochrome C / European / Necrosis / Ion Transport / Biochemistry and cell biology
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