Cell Death

A prototypical Sigma1 receptor antagonist protects against brain ischemia

Cognitive Science / Oxidative Stress / Brain / Low Dose / Female / Animals / Cell Death / Brain Ischemia / Ischemic Stroke / Brain injury / Haloperidol / Rats / Oxidative Damage / Neurosciences / Cerebral Infarction / Neuroprotective Agents / Animals / Cell Death / Brain Ischemia / Ischemic Stroke / Brain injury / Haloperidol / Rats / Oxidative Damage / Neurosciences / Cerebral Infarction / Neuroprotective Agents

JC Virus Induces Nonapoptotic Cell Death of Human Central Nervous System Progenitor Cell-Derived Astrocytes

Electron Microscopy / Stem Cells / Virology / Cell Culture / Biological Sciences / Humans / Cell Death / DNA hybridization / Astrocyte / Glial Cell / Central Nervous System / Astrocytes / Model development / mRna expression levels / X ray diffraction / Necrosis / Capsid Protein / JC Virus / Humans / Cell Death / DNA hybridization / Astrocyte / Glial Cell / Central Nervous System / Astrocytes / Model development / mRna expression levels / X ray diffraction / Necrosis / Capsid Protein / JC Virus

A prototypical Sigma1 receptor antagonist protects against brain ischemia

Cognitive Science / Oxidative Stress / Brain / Low Dose / Female / Animals / Cell Death / Brain Ischemia / Ischemic Stroke / Brain injury / Haloperidol / Rats / Oxidative Damage / Neurosciences / Cerebral Infarction / Neuroprotective Agents / Animals / Cell Death / Brain Ischemia / Ischemic Stroke / Brain injury / Haloperidol / Rats / Oxidative Damage / Neurosciences / Cerebral Infarction / Neuroprotective Agents

De novo-synthesized ceramide signals apoptosis in astrocytes via extracellular signal-regulated kinase

Physiology / Apoptosis / Signal Transduction / Protein Kinases / Animals / Cell Death / Astrocyte / Medical Physiology / Neurons / Astrocytes / Protein kinase B / Rats / Fatty Acid / Wistar Rats / Protein Kinase / Cell Fate / Cell Survival / Extracellular Space / Ceramides / Biochemistry and cell biology / DNA fragmentation / Cell Death / Astrocyte / Medical Physiology / Neurons / Astrocytes / Protein kinase B / Rats / Fatty Acid / Wistar Rats / Protein Kinase / Cell Fate / Cell Survival / Extracellular Space / Ceramides / Biochemistry and cell biology / DNA fragmentation

Using Co-Cultures Expressing Fluorescence Resonance Energy Transfer Based Protein Biosensors to Simultaneously Image Caspase3 and Ca 2+ Signaling

Engineering / Technology / Calcium / Apoptosis / Protein Engineering / Fluorescence Resonance Energy Transfer / Biological Sciences / Caspases / Cercopithecus aethiops / Animals / Cell Death / Calcium Signaling / Fluorescence Imaging / Caspase / Hydrogen Peroxide / Fluorescent Protein / Biosensing Techniques / Fluorescence Resonance Energy Transfer / Biological Sciences / Caspases / Cercopithecus aethiops / Animals / Cell Death / Calcium Signaling / Fluorescence Imaging / Caspase / Hydrogen Peroxide / Fluorescent Protein / Biosensing Techniques

Intracellular zinc increase inhibits p53 −/− pancreatic adenocarcinoma cell growth by ROS/AIF-mediated apoptosis

Medical Microbiology / Mitochondria / Apoptosis / Pancreatic Cancer / Biological Sciences / Caspases / Humans / Reactive Oxygen Species / Cell Death / Physical sciences / Zinc / Gold Standard / Cell nucleus / Growth Inhibition / Cell Proliferation / Intracellular Space / Protein Transport / Biochemistry and cell biology / Adenocarcinoma / Cell Growth / PROTEASOME INHIBITOR / Caspases / Humans / Reactive Oxygen Species / Cell Death / Physical sciences / Zinc / Gold Standard / Cell nucleus / Growth Inhibition / Cell Proliferation / Intracellular Space / Protein Transport / Biochemistry and cell biology / Adenocarcinoma / Cell Growth / PROTEASOME INHIBITOR

Crystal Structure of Mycobacterium tuberculosis Catalase-Peroxidase

Thermodynamics / Molecular Biology / Protein Science / Biological Chemistry / Multidisciplinary / Macromolecular X-Ray Crystallography / Biological Sciences / Crystal structure / Tuberculosis / Mycobacterium tuberculosis / Mutation / Circular Dichroism / Escherichia coli / Mice / Female / Animals / Fluconazole / Cell Death / Physical sciences / Drug Design / Spectrophotometry / Heme / Membrane transport proteins / Enzyme / CHEMICAL SCIENCES / Electrons / Molecular cloning / Active site / Protein Secondary Structure Prediction / Lysine / X ray diffraction / Time Factors / Antifungal Agents / Protein Conformation / Growth Inhibition / Amino Acid Sequence / Protein Binding / Hydrolysis / Cytoplasm / Ligands / Enzyme Catalysis / Protein Transport / Biochemistry and cell biology / Solvents / Dimerization / Adenosine Triphosphate / Adenosine Diphosphate / Molecular Sequence Data / Macromolecular X-Ray Crystallography / Biological Sciences / Crystal structure / Tuberculosis / Mycobacterium tuberculosis / Mutation / Circular Dichroism / Escherichia coli / Mice / Female / Animals / Fluconazole / Cell Death / Physical sciences / Drug Design / Spectrophotometry / Heme / Membrane transport proteins / Enzyme / CHEMICAL SCIENCES / Electrons / Molecular cloning / Active site / Protein Secondary Structure Prediction / Lysine / X ray diffraction / Time Factors / Antifungal Agents / Protein Conformation / Growth Inhibition / Amino Acid Sequence / Protein Binding / Hydrolysis / Cytoplasm / Ligands / Enzyme Catalysis / Protein Transport / Biochemistry and cell biology / Solvents / Dimerization / Adenosine Triphosphate / Adenosine Diphosphate / Molecular Sequence Data

A Novel Immunocytolytic Factor Secreted by Pancreatic Adenocarcinoma

Apoptosis / Pancreatic Cancer / Spleen / Cell line / Humans / Mice / Female / Animals / Cell Death / Clinical Sciences / Western blot / Mechanism of action / Lymphocytes / Surgical / Culture Media / Adenocarcinoma / Immunoblotting / Fas Ligand / Mice / Female / Animals / Cell Death / Clinical Sciences / Western blot / Mechanism of action / Lymphocytes / Surgical / Culture Media / Adenocarcinoma / Immunoblotting / Fas Ligand

Granzyme B of cytotoxic T cells induces extramitochondrial reactive oxygen species production via caspase-dependent NADPH oxidase activation

Immunology / Immune response / Cell Biology / Mitochondria / Apoptosis / Signal Transduction / Caspases / Cell line / Allergy / Mitochondrial DNA / Humans / Reactive Oxygen Species / Mice / Animals / Cell Death / Cytochrome C / NADPH oxidase / Immunology & Cell Biology / Oxidative phosphorylation / Mitochondrial Membrane Potential / Conformational Change / Biochemistry and cell biology / Cytotoxic T cells / Immunoblotting / Signal Transduction / Caspases / Cell line / Allergy / Mitochondrial DNA / Humans / Reactive Oxygen Species / Mice / Animals / Cell Death / Cytochrome C / NADPH oxidase / Immunology & Cell Biology / Oxidative phosphorylation / Mitochondrial Membrane Potential / Conformational Change / Biochemistry and cell biology / Cytotoxic T cells / Immunoblotting

Oxidative stress mediates neuronal DNA damage and apoptosis in response to cytosine arabinoside: AraC causes neuronal apoptosis via oxidative stress

Kinetics / Neurochemistry / Oxidative Stress / DNA damage / Apoptosis / Neuroprotection / Cerebral Cortex / Animals / Cell Death / Vitamin E / Neurons / Uric Acid / Rats / Comet / N-Acetylcysteine / Cell Survival / Neurosciences / Neuronal apoptosis / Neuroprotection / Cerebral Cortex / Animals / Cell Death / Vitamin E / Neurons / Uric Acid / Rats / Comet / N-Acetylcysteine / Cell Survival / Neurosciences / Neuronal apoptosis

Mitochondria: a hub of redox activities and cellular distress control

Genetics / Aging / Oxidative Stress / Mitochondria / Ion Channels / Energy Metabolism / Antioxidants / Mitochondrial DNA / Humans / Reactive Oxygen Species / Stress response / Animals / Cell Death / Cytochrome C / Calcium Signaling / Drug Delivery Systems / Evolutionary History / Electron Transport / Biological evolution / Mitochondrial dysfunction / Mitochondrial Diseases / Calcium Homeostasis / Cell Survival / Oxidation-Reduction / Molecular and Cellular Biochemistry / Low molecular weight / Biochemistry and cell biology / Mitochondrial Proteins / Energy Metabolism / Antioxidants / Mitochondrial DNA / Humans / Reactive Oxygen Species / Stress response / Animals / Cell Death / Cytochrome C / Calcium Signaling / Drug Delivery Systems / Evolutionary History / Electron Transport / Biological evolution / Mitochondrial dysfunction / Mitochondrial Diseases / Calcium Homeostasis / Cell Survival / Oxidation-Reduction / Molecular and Cellular Biochemistry / Low molecular weight / Biochemistry and cell biology / Mitochondrial Proteins

Photoswitchable bactericidal effects from novel silica-coated silver nanoparticles

Nanoparticles / Proceedings / Surface Plasmons / Silica / Cell Death / Surface plasmon resonance / Absorption / Low Power / Electromagnetic Field / Antibacterial activity / Silver Nanoparticle / Surface Plasmon / Thermal Effects / Biomedical Application / Surface plasmon resonance / Absorption / Low Power / Electromagnetic Field / Antibacterial activity / Silver Nanoparticle / Surface Plasmon / Thermal Effects / Biomedical Application

P2X7 Receptor Blockade Prevents ATP Excitotoxicity in Oligodendrocytes and Ameliorates Experimental Autoimmune Encephalomyelitis

Neuroscience / Neurobiology Of Disease / Multiple sclerosis / Calcium / Patch-clamp and imaging techniques / Humans / Anoxia / Glucose / Optic Nerve / Cerebral Cortex / Mice / Animals / Cell Death / The / Glycoproteins / Neurons / Clinical Sciences / Rats / Analysis of Variance / Glial Fibrillary Acidic Protein / Experimental Autoimmune Encephalomyelitis / Cell Survival / Neurosciences / Organic Chemicals / Adenosine Triphosphate / Brain injuries / Neurologic Examination / Humans / Anoxia / Glucose / Optic Nerve / Cerebral Cortex / Mice / Animals / Cell Death / The / Glycoproteins / Neurons / Clinical Sciences / Rats / Analysis of Variance / Glial Fibrillary Acidic Protein / Experimental Autoimmune Encephalomyelitis / Cell Survival / Neurosciences / Organic Chemicals / Adenosine Triphosphate / Brain injuries / Neurologic Examination

P2X7 Receptor Blockade Prevents ATP Excitotoxicity in Oligodendrocytes and Ameliorates Experimental Autoimmune Encephalomyelitis

Neuroscience / Neurobiology Of Disease / Multiple sclerosis / Calcium / Patch-clamp and imaging techniques / Humans / Anoxia / Glucose / Optic Nerve / Cerebral Cortex / Mice / Animals / Cell Death / The / Glycoproteins / Neurons / Clinical Sciences / Rats / Analysis of Variance / Glial Fibrillary Acidic Protein / Experimental Autoimmune Encephalomyelitis / Cell Survival / Neurosciences / Organic Chemicals / Adenosine Triphosphate / Brain injuries / Neurologic Examination / Humans / Anoxia / Glucose / Optic Nerve / Cerebral Cortex / Mice / Animals / Cell Death / The / Glycoproteins / Neurons / Clinical Sciences / Rats / Analysis of Variance / Glial Fibrillary Acidic Protein / Experimental Autoimmune Encephalomyelitis / Cell Survival / Neurosciences / Organic Chemicals / Adenosine Triphosphate / Brain injuries / Neurologic Examination

P2X7 Receptor Blockade Prevents ATP Excitotoxicity in Oligodendrocytes and Ameliorates Experimental Autoimmune Encephalomyelitis

Neuroscience / Neurobiology Of Disease / Multiple sclerosis / Calcium / Patch-clamp and imaging techniques / Humans / Anoxia / Glucose / Optic Nerve / Cerebral Cortex / Mice / Animals / Cell Death / The / Glycoproteins / Neurons / Clinical Sciences / Rats / Analysis of Variance / Glial Fibrillary Acidic Protein / Experimental Autoimmune Encephalomyelitis / Cell Survival / Neurosciences / Organic Chemicals / Adenosine Triphosphate / Brain injuries / Neurologic Examination / Humans / Anoxia / Glucose / Optic Nerve / Cerebral Cortex / Mice / Animals / Cell Death / The / Glycoproteins / Neurons / Clinical Sciences / Rats / Analysis of Variance / Glial Fibrillary Acidic Protein / Experimental Autoimmune Encephalomyelitis / Cell Survival / Neurosciences / Organic Chemicals / Adenosine Triphosphate / Brain injuries / Neurologic Examination

Mitochondria: a hub of redox activities and cellular distress control

Genetics / Aging / Oxidative Stress / Mitochondria / Ion Channels / Energy Metabolism / Antioxidants / Mitochondrial DNA / Humans / Reactive Oxygen Species / Stress response / Animals / Cell Death / Cytochrome C / Calcium Signaling / Drug Delivery Systems / Evolutionary History / Electron Transport / Biological evolution / Mitochondrial dysfunction / Mitochondrial Diseases / Calcium Homeostasis / Cell Survival / Oxidation-Reduction / Molecular and Cellular Biochemistry / Low molecular weight / Biochemistry and cell biology / Mitochondrial Proteins / Energy Metabolism / Antioxidants / Mitochondrial DNA / Humans / Reactive Oxygen Species / Stress response / Animals / Cell Death / Cytochrome C / Calcium Signaling / Drug Delivery Systems / Evolutionary History / Electron Transport / Biological evolution / Mitochondrial dysfunction / Mitochondrial Diseases / Calcium Homeostasis / Cell Survival / Oxidation-Reduction / Molecular and Cellular Biochemistry / Low molecular weight / Biochemistry and cell biology / Mitochondrial Proteins
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