Cell Death

Cervical cancer isolate PT3, super-permissive for adeno-associated virus replication, over-expresses DNA polymerase δ, PCNA, RFC and RPA

Gene Therapy / DNA replication / Gene expression / Biological Sciences / Cell line / Humans / Keratinocytes / Female / Cell Death / Adeno-associated virus / Cervical Cancer / DNA Polymerase / Humans / Keratinocytes / Female / Cell Death / Adeno-associated virus / Cervical Cancer / DNA Polymerase

Cardenolide Glycosides from Pergularia tomentosa and Their Proapoptotic Activity in Kaposi\'s Sarcoma Cells

Natural Products / Egypt / Pharmacognosy / Medicinal Plants / Cytotoxicity / Apoptosis / Structural Analysis / Biological Sciences / Cell line / Humans / ROOT / Cell Death / Plant Roots / CHEMICAL SCIENCES / Apoptose / Isolation / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Natural / Asclepiadaceae / Biological activity / Glycosides / Apoptosis / Structural Analysis / Biological Sciences / Cell line / Humans / ROOT / Cell Death / Plant Roots / CHEMICAL SCIENCES / Apoptose / Isolation / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Natural / Asclepiadaceae / Biological activity / Glycosides

A Novel Immunocytolytic Factor Secreted by Pancreatic Adenocarcinoma

Apoptosis / Pancreatic Cancer / Spleen / Cell line / Humans / Mice / Female / Animals / Cell Death / Clinical Sciences / Western blot / Mechanism of action / Lymphocytes / Surgical / Culture Media / Adenocarcinoma / Immunoblotting / Fas Ligand / Mice / Female / Animals / Cell Death / Clinical Sciences / Western blot / Mechanism of action / Lymphocytes / Surgical / Culture Media / Adenocarcinoma / Immunoblotting / Fas Ligand

p53 signaling in response to increased DNA damage sensitizes AML1-ETO cells to stress-induced death

DNA damage / DNA repair / Cell Division / Humans / Blood / Cell Death / Clinical Sciences / Newborn Infant / Base Sequence / Cell Death / Clinical Sciences / Newborn Infant / Base Sequence

Testosterone promotes apoptotic damage in human renal tubular cells

Nephrology / Urology / Dialysis / Apoptosis / Caspases / Cell line / Humans / Testosterone / Kidney / End Stage Renal Disease / Cell Death / Androgens / Morphological Analysis / Clinical Sciences / Caspase / Western blot / Androgen Receptor / Chronic Renal Disease / Primary Culture / Level / Proximal Tubule / Cell Survival / Propidium Iodide / Terminal Deoxynucleotidyl Transferase / Fas Ligand / Cell line / Humans / Testosterone / Kidney / End Stage Renal Disease / Cell Death / Androgens / Morphological Analysis / Clinical Sciences / Caspase / Western blot / Androgen Receptor / Chronic Renal Disease / Primary Culture / Level / Proximal Tubule / Cell Survival / Propidium Iodide / Terminal Deoxynucleotidyl Transferase / Fas Ligand

Biologic scaffolds composed of central nervous system extracellular matrix

Biomaterials / Tissue Engineering / Regenerative Medicine / Multidisciplinary / Extracellular Matrix / DNA / Cell Differentiation / Humans / Animals / Cell Death / Central Nervous System / Chemotaxis / Decellularization / Rats / Sus Scrofa / Biocompatible Materials / Cell Survival / Extracellular Matrix Proteins / DNA / Cell Differentiation / Humans / Animals / Cell Death / Central Nervous System / Chemotaxis / Decellularization / Rats / Sus Scrofa / Biocompatible Materials / Cell Survival / Extracellular Matrix Proteins

Aurora kinase inhibitor ZM447439 induces apoptosis via mitochondrial pathways

Flow Cytometry / Mitochondria / Apoptosis / Colorectal cancer / Humans / Cell Death / Kinase inhibitor / Biochemical / Time Dependent / BIOCHEMICAL PHARMACOLOGY / Aurora kinases / Mitochondrial Membrane Potential / Protein Kinase Inhibitors / Benzamides / Quinazolines / Cell Death / Kinase inhibitor / Biochemical / Time Dependent / BIOCHEMICAL PHARMACOLOGY / Aurora kinases / Mitochondrial Membrane Potential / Protein Kinase Inhibitors / Benzamides / Quinazolines

Selective dopaminergic vulnerability: 3,4-dihydroxyphenylacetaldehyde targets mitochondria

Membrane Proteins / Enzyme Inhibitors / Mitochondria / Ion Channels / Dopamine / Cell Differentiation / Animals / Male / Cell Death / Substantia nigra / Cyclosporine / Respiration / Neuronal Differentiation / Mitochondrial dysfunction / Rats / Disease Progression / Mechanism of action / Nerve Growth Factor / Trifluoperazine / Monoamine oxidase / Parkinson Disease / Biochemistry and cell biology / Dopamine antagonists / Cell Differentiation / Animals / Male / Cell Death / Substantia nigra / Cyclosporine / Respiration / Neuronal Differentiation / Mitochondrial dysfunction / Rats / Disease Progression / Mechanism of action / Nerve Growth Factor / Trifluoperazine / Monoamine oxidase / Parkinson Disease / Biochemistry and cell biology / Dopamine antagonists

Administration of Human Protein-C concentrate prevents apoptotic brain cell death after experimental sepsis

Cognitive Science / Flow Cytometry / Immunohistochemistry / Apoptosis / Caspases / Brain / Animals / Male / Cell Death / Cytochrome C / Sepsis / Astrocyte / Rat Brain / Cytoprotection / Neurons / Astrocytes / Apoptose / Rats / Time Dependent / Endothelial cell / Time Factors / Wistar Rats / Neurosciences / Cecal ligation and puncture / Brain / Animals / Male / Cell Death / Cytochrome C / Sepsis / Astrocyte / Rat Brain / Cytoprotection / Neurons / Astrocytes / Apoptose / Rats / Time Dependent / Endothelial cell / Time Factors / Wistar Rats / Neurosciences / Cecal ligation and puncture

Apoptosis in substantia nigra following developmental striatal excitotoxic injury

Electron Microscopy / DNA damage / Apoptosis / Multidisciplinary / DNA / Female / Animals / Male / Cell Death / Substantia nigra / Neurons / Tyrosine Hydroxylase / Rats / Time Course / Substantia nigra pars compacta (SNpc) / Female / Animals / Male / Cell Death / Substantia nigra / Neurons / Tyrosine Hydroxylase / Rats / Time Course / Substantia nigra pars compacta (SNpc)

Enhanced Astrocytic Ca2+ Signals Contribute to Neuronal Excitotoxicity after Status Epilepticus

Neuroscience / Calcium / Patch-clamp and imaging techniques / Mice / Glutamate receptors / Animals / Male / Cell Death / Astrocyte / Calcium Signaling / The / Neurons / Astrocytes / Pilocarpine / Time Factors / Status Epilepticus / Chelating Agents / Piperidines / Animals / Male / Cell Death / Astrocyte / Calcium Signaling / The / Neurons / Astrocytes / Pilocarpine / Time Factors / Status Epilepticus / Chelating Agents / Piperidines

SCaMC-1 promotes cancer cell survival by desensitizing mitochondrial permeability transition via ATP/ADP-mediated matrix Ca2+ buffering

Calcium / Oxidative Stress / Mitochondria / Biological Sciences / Cercopithecus aethiops / Cell line / Cancer Therapy / Permeability / Mice / Animals / Negative Feedback / Cell Death / Necrosis / Neoplasms / Mitochondrial Permeability Transition Pore / Gene Expression Analysis / Calcium Binding Proteins / Cell Survival / Nucleotides / Adenosine Triphosphate / Adenosine Diphosphate / Cell line / Cancer Therapy / Permeability / Mice / Animals / Negative Feedback / Cell Death / Necrosis / Neoplasms / Mitochondrial Permeability Transition Pore / Gene Expression Analysis / Calcium Binding Proteins / Cell Survival / Nucleotides / Adenosine Triphosphate / Adenosine Diphosphate

Autonomous in Vitro Anticancer Drug Release from Mesoporous Silica Nanoparticles by pH-Sensitive Nanovalves

Humans / Porosity / Mice / Animals / Cell Death / Nanostructures / Drug Delivery Systems / The / CHEMICAL SCIENCES / Particle Size / Surface Properties / Cell Proliferation / Silicon Dioxide / Hydrogen-Ion Concentration / Antineoplastic Agents / Nanostructures / Drug Delivery Systems / The / CHEMICAL SCIENCES / Particle Size / Surface Properties / Cell Proliferation / Silicon Dioxide / Hydrogen-Ion Concentration / Antineoplastic Agents

A Novel Isoform of Acetylcholinesterase Exacerbates Photoreceptors Death after Photic Stress

Ophthalmology / Death / Stress / Confocal Microscopy / In Situ Hybridization / Biological Sciences / Animals / Male / Cell Death / Retina / Acetylcholinesterase / Light / Retinal Degeneration / Rats / Isoenzymes / Electroretinogram / Biological Sciences / Animals / Male / Cell Death / Retina / Acetylcholinesterase / Light / Retinal Degeneration / Rats / Isoenzymes / Electroretinogram

Triptolide sensitizes resistant cholangiocarcinoma cells to TRAIL-induced apoptosis

Apoptosis / Caspases / Humans / Resistance / Cell Death / Mitogen Activated Protein Kinase / Trail / Caspase / Anticancer / Apoptose / Cholangiocarcinoma / Diterpenes / Tumor necrosis factor-alpha / Down-Regulation / Mitogen Activated Protein Kinase / Trail / Caspase / Anticancer / Apoptose / Cholangiocarcinoma / Diterpenes / Tumor necrosis factor-alpha / Down-Regulation

Uncaria tomentosa acts as a potent TNF-α inhibitor through NF-κB

Complementary and Alternative Medicine / Plant Biology / Inflammation / Ethnopharmacology / Pharmacognosy / Phytotherapy / Cell line / Humans / Cell Death / NF-kappa B / Anti-inflammatory agents / Lipopolysaccharides / Plant extracts / Tumor necrosis factor-alpha / Anti Inflammatory Activity / Medicinal Plant / Phytotherapy / Cell line / Humans / Cell Death / NF-kappa B / Anti-inflammatory agents / Lipopolysaccharides / Plant extracts / Tumor necrosis factor-alpha / Anti Inflammatory Activity / Medicinal Plant
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