DNA damage

Structural study of DNA duplex containing an N-(2-deoxy- -D-erythro-pentofuranosyl) formamide frameshift by NMR and restrained molecular dynamics

Nuclear Magnetic Resonance / Information Extraction / Magnetic Resonance Spectroscopy / DNA damage / Biological Sciences / DNA / Environmental Sciences / Temperature / Nucleic Acids / Base Sequence / Protons / Molecular Dynamic Simulation / Nucleic Acid Conformation / Molecular Structure / Ribose / DNA / Environmental Sciences / Temperature / Nucleic Acids / Base Sequence / Protons / Molecular Dynamic Simulation / Nucleic Acid Conformation / Molecular Structure / Ribose

Asafoetida inhibits early events of carcinogenesis

Traditional Medicine / Life Sciences / Oxidative Stress / Medicinal Plants / DNA damage / Free Radical / DNA / Antioxidants / Phytotherapy / Mice / Female / Animals / Chemoprevention / Skin / Proteins / Hydrogen Peroxide / Plant extracts / Topical Drug Administration / Ferula / Oxidation-Reduction / Xanthine Oxidase / Biochemistry and cell biology / Enzyme Induction / Skin Neoplasms / Dna Synthesis / Free Radical / DNA / Antioxidants / Phytotherapy / Mice / Female / Animals / Chemoprevention / Skin / Proteins / Hydrogen Peroxide / Plant extracts / Topical Drug Administration / Ferula / Oxidation-Reduction / Xanthine Oxidase / Biochemistry and cell biology / Enzyme Induction / Skin Neoplasms / Dna Synthesis

Inhibition of Aurora A in response to DNA damage

Cancer / Cell Cycle / DNA damage / Apoptosis / Molecular Mechanics / Western blotting / Signal Transduction / Mitosis / Cell line / Epidermal Growth Factor/ErbB receptors / Oncogene / Clinical Sciences / Base Sequence / Aurora kinases / Mutagens / Transient Expression / Western blotting / Signal Transduction / Mitosis / Cell line / Epidermal Growth Factor/ErbB receptors / Oncogene / Clinical Sciences / Base Sequence / Aurora kinases / Mutagens / Transient Expression

Persistent DNA Damage after High Dose In Vivo Gamma Exposure of Minipig Skin

Engineering / Physics / Chemistry / Biology / Gamma Rays / DNA damage / DNA repair / Apoptosis / Medicine / Multidisciplinary / Animals / Skin / Phosphorylation / PLoS one / Histones / Swine / Cell Cycle Proteins / DNA binding proteins / DNA damage / DNA repair / Apoptosis / Medicine / Multidisciplinary / Animals / Skin / Phosphorylation / PLoS one / Histones / Swine / Cell Cycle Proteins / DNA binding proteins

Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155

MicroRNA / Immunohistochemistry / DNA damage / DNA repair / In Situ Hybridization / Humans / Female / HIstone Deacetylase / Immunoprecipitation / microRNAs / Tumor Suppressor Gene / Microarray Analysis / Analysis of Variance / Chromatin Immunoprecipitation / Cell Cycle regulation / Humans / Female / HIstone Deacetylase / Immunoprecipitation / microRNAs / Tumor Suppressor Gene / Microarray Analysis / Analysis of Variance / Chromatin Immunoprecipitation / Cell Cycle regulation

Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA155

MicroRNA / Immunohistochemistry / DNA damage / DNA repair / In Situ Hybridization / Humans / Female / HIstone Deacetylase / Immunoprecipitation / microRNAs / Tumor Suppressor Gene / Microarray Analysis / Analysis of Variance / Chromatin Immunoprecipitation / Cell Cycle regulation / Humans / Female / HIstone Deacetylase / Immunoprecipitation / microRNAs / Tumor Suppressor Gene / Microarray Analysis / Analysis of Variance / Chromatin Immunoprecipitation / Cell Cycle regulation

Oxidative stress mediates neuronal DNA damage and apoptosis in response to cytosine arabinoside: AraC causes neuronal apoptosis via oxidative stress

Kinetics / Neurochemistry / Oxidative Stress / DNA damage / Apoptosis / Neuroprotection / Cerebral Cortex / Animals / Cell Death / Vitamin E / Neurons / Uric Acid / Rats / Comet / N-Acetylcysteine / Cell Survival / Neurosciences / Neuronal apoptosis / Neuroprotection / Cerebral Cortex / Animals / Cell Death / Vitamin E / Neurons / Uric Acid / Rats / Comet / N-Acetylcysteine / Cell Survival / Neurosciences / Neuronal apoptosis

Persistent DNA Damage after High Dose In Vivo Gamma Exposure of Minipig Skin

Engineering / Physics / Chemistry / Biology / Gamma Rays / DNA damage / DNA repair / Apoptosis / Medicine / Multidisciplinary / Animals / Skin / Phosphorylation / PLoS one / Histones / Swine / Cell Cycle Proteins / DNA binding proteins / DNA damage / DNA repair / Apoptosis / Medicine / Multidisciplinary / Animals / Skin / Phosphorylation / PLoS one / Histones / Swine / Cell Cycle Proteins / DNA binding proteins

Cellular Response to DNA Damage

Radiation / DNA damage / DNA repair / Multidisciplinary / Signal Transduction / DNA / Humans / Histones / Neoplasms / Genetic Recombination / Protein Conformation / Homologous Recombination / DNA / Humans / Histones / Neoplasms / Genetic Recombination / Protein Conformation / Homologous Recombination

Cellular Response to DNA Damage

Radiation / DNA damage / DNA repair / Multidisciplinary / Signal Transduction / DNA / Humans / Histones / Neoplasms / Genetic Recombination / Protein Conformation / Homologous Recombination / DNA / Humans / Histones / Neoplasms / Genetic Recombination / Protein Conformation / Homologous Recombination

Auraptene from Ferula szowitsiana protects human peripheral lymphocytes against oxidative stress

Oxidative Stress / DNA damage / Biological Sciences / Antioxidants / Phytotherapy / Humans / CHEMICAL SCIENCES / Hydrogen Peroxide / Comet Assay / Coumarins / Ascorbic Acid / Adult / Ferula / Lymphocytes / Molecular Structure / Humans / CHEMICAL SCIENCES / Hydrogen Peroxide / Comet Assay / Coumarins / Ascorbic Acid / Adult / Ferula / Lymphocytes / Molecular Structure

Nuclear phosphoinositide 3-kinase beta controls double-strand break DNA repair

DNA replication / DNA damage / DNA repair / Multidisciplinary / Mice / Animals / Cell nucleus / Neoplasms / Genomic instability / Protein isoforms / Cell Cycle Proteins / Animals / Cell nucleus / Neoplasms / Genomic instability / Protein isoforms / Cell Cycle Proteins

Nuclear phosphoinositide 3-kinase   controls double-strand break DNA repair

DNA replication / DNA damage / DNA repair / Multidisciplinary / Mice / Animals / Cell nucleus / Neoplasms / Genomic instability / Protein isoforms / Cell Cycle Proteins / Animals / Cell nucleus / Neoplasms / Genomic instability / Protein isoforms / Cell Cycle Proteins

Nuclear phosphoinositide 3-kinase β controls double-strand break DNA repair

DNA replication / DNA damage / DNA repair / Multidisciplinary / Mice / Animals / Cell nucleus / Neoplasms / Genomic instability / Protein isoforms / Cell Cycle Proteins / Animals / Cell nucleus / Neoplasms / Genomic instability / Protein isoforms / Cell Cycle Proteins

XPC polymorphisms play a role in tissue-specific carcinogenesis: a meta-analysis

Genetics / Polymorphism / Breast Cancer / DNA damage / Lung Cancer / Head and Neck / Bladder Cancer / Humans / Statistical Significance / Nucleotide Excision Repair / Meta Analysis / European / Neoplasms / Large Scale / Case Control Study / DNA binding proteins / Cancer Risk / Confidence Interval / Tissue Specificity / Head and Neck / Bladder Cancer / Humans / Statistical Significance / Nucleotide Excision Repair / Meta Analysis / European / Neoplasms / Large Scale / Case Control Study / DNA binding proteins / Cancer Risk / Confidence Interval / Tissue Specificity

Oxidative DNA Damage as a Potential Early Biomarker of Helicobacter pylori Associated Carcinogenesis

Oxidative Stress / Helicobacter pylori / DNA damage / Humans / Female / Male / Polymerase Chain Reaction / Follow-up studies / Middle Aged / Adult / Prognosis / Biological markers / Gastritis / Oncology and Molecular Pathology / Male / Polymerase Chain Reaction / Follow-up studies / Middle Aged / Adult / Prognosis / Biological markers / Gastritis / Oncology and Molecular Pathology
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