DNA damage

DNA damage responses and oxidative stress in dyskeratosis congenita

Radiation / Oxidative Stress / DNA damage / Apoptosis / Multidisciplinary / Humans / Reactive Oxygen Species / PLoS one / T lymphocytes / Biological markers / Antineoplastic Agents / Gene Expression Regulation / Humans / Reactive Oxygen Species / PLoS one / T lymphocytes / Biological markers / Antineoplastic Agents / Gene Expression Regulation

DNA damage and repair in human lymphocytes and gastric mucosa cells exposed to chromium and curcumin

DNA damage / DNA repair / Humans / Curcumin / Chromium / Time Factors / Lymphocytes / Teratogenesis / Time Factors / Lymphocytes / Teratogenesis

Cdk1 Participates in BRCA1-Dependent S Phase Checkpoint Control in Response to DNA Damage

DNA damage / DNA repair / Signal Transduction / Cell and Molecular Biology / Biological Sciences / Cell line / Humans / Mutation / Phosphorylation / Cell Cycle Proteins / DNA binding proteins / Cell line / Humans / Mutation / Phosphorylation / Cell Cycle Proteins / DNA binding proteins

Protein kinase Cη activates NF-κB in response to camptothecin-induced DNA damage

DNA damage / Humans / Adaptive Immunity / Drug Resistance / Cell Death / NF-kappa B / Transcription Factor / Cell nucleus / Camptothecin / Protein Kinase / Biochemistry and cell biology / Anticancer Drug / NF-kappa B / Transcription Factor / Cell nucleus / Camptothecin / Protein Kinase / Biochemistry and cell biology / Anticancer Drug

MicroRNA-449a Enhances Radiosensitivity in CL1-0 Lung Adenocarcinoma Cells

Cell Cycle / DNA damage / Apoptosis / Multidisciplinary / Humans / PLoS one / microRNAs / Cell Survival / Radiation Tolerance / Adenocarcinoma / Gene expression profiling / PLoS one / microRNAs / Cell Survival / Radiation Tolerance / Adenocarcinoma / Gene expression profiling

Resveratrol, a natural aryl hydrocarbon receptor antagonist, protects lung from DNA damage and apoptosis caused by benzo[a]pyrene

Flow Cytometry / Immunohistochemistry / Enzyme Inhibitors / DNA damage / Apoptosis / Prevention / Western blotting / DNA / Toxicity / Mice / Applied / Animals / Male / Cell Death / Cytoprotection / Lung / tESTIS / Aryl Hydrocarbon Receptor / Apoptose / Public health systems and services research / Stilbenes / Reproductive / Spermatozoa / Somatic Cell Count / Applied Toxicology / Prevention / Western blotting / DNA / Toxicity / Mice / Applied / Animals / Male / Cell Death / Cytoprotection / Lung / tESTIS / Aryl Hydrocarbon Receptor / Apoptose / Public health systems and services research / Stilbenes / Reproductive / Spermatozoa / Somatic Cell Count / Applied Toxicology

DNA damage response: A barrier or a path to tumor progression?

DNA damage / Signal Transduction / Humans / Disease Progression

Mitochondrial Telomerase Protects Cancer Cells from Nuclear DNA Damage and Apoptosis

Mitochondria / Confocal Microscopy / DNA damage / Apoptosis / Multidisciplinary / Telomerase / Cell line / Humans / Reactive Oxygen Species / PLoS one / Hydrogen Peroxide / Cell nucleus / HeLa cells / Neoplasms / Transfection / Oxidants / Protein Transport / Immunoblotting / Telomerase / Cell line / Humans / Reactive Oxygen Species / PLoS one / Hydrogen Peroxide / Cell nucleus / HeLa cells / Neoplasms / Transfection / Oxidants / Protein Transport / Immunoblotting

Oxidized Extracellular DNA as a Stress Signal in Human Cells

Oxidative Stress / DNA damage / Apoptosis / DNA / Humans / Reactive Oxygen Species / Animals / Human Genome / Oxidation-Reduction / Reactive Oxygen Species / Animals / Human Genome / Oxidation-Reduction

Mitochondrial DNA analysis in Parkinson\'s disease

Cognitive Science / DNA damage / Movement disorders / Mitochondrial DNA / Humans / Substantia nigra / Clinical Sciences / Parkinson Disease / Substantia nigra / Clinical Sciences / Parkinson Disease

Schizophrenia as segmental progeria

Schizophrenia / DNA damage / Apoptosis / Mammals / Humans / Animals / Progeria / Public health systems and services research / Neoplasms / Animals / Progeria / Public health systems and services research / Neoplasms

Schizophrenia as segmental progeria

Schizophrenia / DNA damage / Apoptosis / Mammals / Humans / Animals / Progeria / Public health systems and services research / Neoplasms / Animals / Progeria / Public health systems and services research / Neoplasms

NUMB controls p53 tumour suppressor activity

Breast Cancer / Membrane Proteins / DNA damage / Multidisciplinary / Gene Silencing / Nature / Humans / Ubiquitin ligase / Prognosis / Cell Fate / Protein Binding / Plasma Membrane / Ubiquitination / Nature / Humans / Ubiquitin ligase / Prognosis / Cell Fate / Protein Binding / Plasma Membrane / Ubiquitination

RECQL4 localizes to mitochondria and preserves mitochondrial DNA integrity

Aging / Mitochondria / DNA damage / Biological Sciences / mtDNA / Mitochondrial DNA / Humans / Mice / Animals / Cell Fractionation / HeLa cells / Genomic instability / Age Factors / RecQ Helicases / Mitochondrial DNA / Humans / Mice / Animals / Cell Fractionation / HeLa cells / Genomic instability / Age Factors / RecQ Helicases

NUMB controls p53 tumour suppressor activity

Breast Cancer / Membrane Proteins / DNA damage / Multidisciplinary / Gene Silencing / Nature / Humans / Ubiquitin ligase / Prognosis / Cell Fate / Protein Binding / Plasma Membrane / Ubiquitination / Nature / Humans / Ubiquitin ligase / Prognosis / Cell Fate / Protein Binding / Plasma Membrane / Ubiquitination

WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity

DNA damage / Transcription Factors / Multidisciplinary / Nature / Humans / Mice / Animals / Cell Death / Chromatin remodeling / Phosphorylation / Williams- Beuren Syndrome / Nucleosomes / Transcription Factor / Phosphotyrosine / Histones / DNA damage response / Genomic instability / Tyrosine Kinase / Mice / Animals / Cell Death / Chromatin remodeling / Phosphorylation / Williams- Beuren Syndrome / Nucleosomes / Transcription Factor / Phosphotyrosine / Histones / DNA damage response / Genomic instability / Tyrosine Kinase
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