Down-Regulation

Nitric Oxide Exposure Diverts Neural Stem Cell Fate from Neurogenesis Towards Astrogliogenesis

Technology / Stem Cells / Gene expression / Biological Sciences / Neural stem cell / Cell Differentiation / Nitric oxide / Female / Animals / Cell Death / STEM / Neurons / Astrocytes / Rats / Oxygen / Glial Fibrillary Acidic Protein / Down-Regulation / Cell Differentiation / Nitric oxide / Female / Animals / Cell Death / STEM / Neurons / Astrocytes / Rats / Oxygen / Glial Fibrillary Acidic Protein / Down-Regulation

Enhanced expression of DNA polymerase eta contributes to cisplatin resistance of ovarian cancer stem cells

Flow Cytometry / DNA damage / DNA repair / Multidisciplinary / DNA / Humans / Mice / Female / Animals / Recurrence / Cisplatin / microRNAs / Cell Survival / Down-Regulation / Humans / Mice / Female / Animals / Recurrence / Cisplatin / microRNAs / Cell Survival / Down-Regulation

Blockade of CD11a by Efalizumab in Psoriasis Patients Induces a Unique State of T-Cell Hyporesponsiveness

T cell receptor / Humans / Female / Male / Monoclonal Antibodies / Animal Model / Psoriasis / Clinical Sciences / T lymphocytes / Aged / Middle Aged / Adult / T cell activation / Mechanism of action / INVESTIGATIVE / Interleukin / Down-Regulation / Animal Model / Psoriasis / Clinical Sciences / T lymphocytes / Aged / Middle Aged / Adult / T cell activation / Mechanism of action / INVESTIGATIVE / Interleukin / Down-Regulation

Non-hematopoietic cells contribute to protective tolerance to Aspergillus fumigatus via a TRIF pathway converging on IDO

Immunology / Innate immunity / Disease susceptibility / Neuroimmunology / Signal Transduction / Toll like receptor signaling / Molecular and cellular biology / Cellular and Molecular Immunology / Mice / Adaptive Immunity / Animals / Pneumonia / Dendritic cell / Bone marrow / Aspergillus fumigatus / Epithelial cells / Immune Tolerance / Interleukin / Down-Regulation / Interferon gamma / Ido / Hematopoietic Stem Cell Transplantation / Toll like receptor signaling / Molecular and cellular biology / Cellular and Molecular Immunology / Mice / Adaptive Immunity / Animals / Pneumonia / Dendritic cell / Bone marrow / Aspergillus fumigatus / Epithelial cells / Immune Tolerance / Interleukin / Down-Regulation / Interferon gamma / Ido / Hematopoietic Stem Cell Transplantation

TRAIL/Apo-2 Ligand Induces Primary Plasma Cell Apoptosis

Immunology / Immunology of the Gut / Apoptosis / Caspases / Cell Differentiation / Humans / Mice / Animals / NF-kappa B / The / T cells / Tumor necrosis factor-alpha / Ligands / Interleukin / Down-Regulation / Humans / Mice / Animals / NF-kappa B / The / T cells / Tumor necrosis factor-alpha / Ligands / Interleukin / Down-Regulation

EZH2 Is Essential for Glioblastoma Cancer Stem Cell Maintenance

Cancer / Transcription Factors / Humans / Mice / Glioblastoma / Animals / Cancer Stem Cell / DNA binding proteins / Gene expression profiling / Down-Regulation / Animals / Cancer Stem Cell / DNA binding proteins / Gene expression profiling / Down-Regulation

DREAM Is a Critical Transcriptional Repressor for Pain Modulation

Animal Behavior / Chronic Pain / Inflammation / Membrane Proteins / Biological Sciences / Learning and Memory / Mice / Animals / Spinal Cord / Cell / Heart / Neurons / Motor Function / Presenilin-2 / Base Sequence / Calcium Binding Proteins / Inflammatory Pain / Hyperalgesia / Pain Modulation / Down-Regulation / Learning and Memory / Mice / Animals / Spinal Cord / Cell / Heart / Neurons / Motor Function / Presenilin-2 / Base Sequence / Calcium Binding Proteins / Inflammatory Pain / Hyperalgesia / Pain Modulation / Down-Regulation

Boswellia sacra essential oil induces tumor cell-specific apoptosis and suppresses tumor aggressiveness in cultured human breast cancer cells

Complementary and Alternative Medicine / Cell Cycle / Apoptosis / Humans / Neoplasm Invasiveness / Gas Chromatography/mass Spectrometry / Cell Proliferation / Plant Oils / Down-Regulation / Gas Chromatography/mass Spectrometry / Cell Proliferation / Plant Oils / Down-Regulation

Human DNA polymerase iota protects cells against oxidative stress

Oxidative Stress / DNA damage / DNA repair / Biological Sciences / Cell line / Humans / Cell Death / BER / Cytoprotection / Chromatin / Hydrogen Peroxide / Human Fibroblasts / Protein Binding / DNA binding proteins / DNA Polymerase / Down-Regulation / Humans / Cell Death / BER / Cytoprotection / Chromatin / Hydrogen Peroxide / Human Fibroblasts / Protein Binding / DNA binding proteins / DNA Polymerase / Down-Regulation

Natriuretic Peptide Receptor A as a Novel Target for Prostate Cancer

Immunohistochemistry / Prostate Cancer / Apoptosis / Molecular Biology Cancer / Cell line / Humans / Mice / Animals / Male / Peptides / Rats / Western blot / Disease Progression / Rabbits / Down-Regulation / Humans / Mice / Animals / Male / Peptides / Rats / Western blot / Disease Progression / Rabbits / Down-Regulation

MicroRNA-9 promotes tumor metastasis via repressing E-cadherin in esophageal squamous cell carcinoma

Fluorescence Microscopy / Treatment Outcome / In Situ Hybridization / Humans / Beta-Catenin / microRNAs / Oral Squamous Cell Carcinoma (OSCC) / Prognosis / Disease Progression / Proportional Hazards Models / Gene expression profiling / Down-Regulation / microRNAs / Oral Squamous Cell Carcinoma (OSCC) / Prognosis / Disease Progression / Proportional Hazards Models / Gene expression profiling / Down-Regulation

Eupafolin, a flavonoid isolated from Artemisia princeps, induced apoptosis in human cervical adenocarcinoma HeLa cells

Nutrition and Dietetics / Kinetics / Mitochondria / Apoptosis / Caspases / Humans / Permeability / Female / Artemisia / HeLa cells / Food Sciences / Flavones / Adenocarcinoma / Down-Regulation / DNA fragmentation / Humans / Permeability / Female / Artemisia / HeLa cells / Food Sciences / Flavones / Adenocarcinoma / Down-Regulation / DNA fragmentation

Glucosylceramide Synthase Blockade Down-Regulates P-Glycoprotein and Resensitizes Multidrug-Resistant Breast Cancer Cells to Anticancer Drugs

Cancer / Humans / Multidrug Resistance / P-glycoprotein / Paclitaxel / Sphingolipids / Doxorubicin / Transfection / Gangliosides / Vinblastine / Adenocarcinoma / Down-Regulation / Sphingolipids / Doxorubicin / Transfection / Gangliosides / Vinblastine / Adenocarcinoma / Down-Regulation

Cancer as “Rejuvenescence”

Cancer / Aging / Apoptosis / Multidisciplinary / Signal Transduction / Humans / Animals / Phenotype / Oncogenes / Neoplasms / Down-Regulation / Humans / Animals / Phenotype / Oncogenes / Neoplasms / Down-Regulation

Clinical response to chemotherapy in oesophageal adenocarcinoma patients is linked to defects in mitochondria

Proteomics / Treatment Outcome / Mitochondria / Biopsy / RNA interference / Humans / Tandem Mass Spectrometry / High Performance Liquid Chromatography / Clinical Sciences / Cisplatin / Aged / Middle Aged / Transfection / Individualized Medicine / Adenocarcinoma / Down-Regulation / Humans / Tandem Mass Spectrometry / High Performance Liquid Chromatography / Clinical Sciences / Cisplatin / Aged / Middle Aged / Transfection / Individualized Medicine / Adenocarcinoma / Down-Regulation

Loss of stearoyl-CoA desaturase expression is a frequent event in prostate carcinoma

RNA / Cancer / Immunohistochemistry / Humans / Fatty acids / Nucleic acid hybridization / Male / Polymerase Chain Reaction / Lipid metabolism / Phenotype / Carcinoma / Disease Progression / Down-Regulation / Stearoyl-CoA desaturase / Nucleic acid hybridization / Male / Polymerase Chain Reaction / Lipid metabolism / Phenotype / Carcinoma / Disease Progression / Down-Regulation / Stearoyl-CoA desaturase
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