Drug Resistance

Confronting parasites from Canada

Genetics / Leishmania / Biological Sciences / Canada / Humans / TRENDS / Animals / Drug Resistance / Parasites / Fasciola hepatica / Interleukins / Entamoeba histolytica / Parasitic Diseases / Anthelmintics / Drug Targeting / Helminthiasis / Gene Expression Regulation / TRENDS / Animals / Drug Resistance / Parasites / Fasciola hepatica / Interleukins / Entamoeba histolytica / Parasitic Diseases / Anthelmintics / Drug Targeting / Helminthiasis / Gene Expression Regulation

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Schistosomiasis control: praziquantel forever?

Drug Discovery / Biological Sciences / Humans / Resistance / Schistosomiasis / Animals / Drug Resistance / Schistosoma Mansoni / Praziquantel / Animals / Drug Resistance / Schistosoma Mansoni / Praziquantel

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Quasispecies Made Simple

RNA viruses / Biological Sciences / Mutation / Mathematical Sciences / Drug Resistance / Genotype / Viral Infection / Genetic variation / Mutation Rate / Genotype / Viral Infection / Genetic variation / Mutation Rate

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ATPase family AAA domain-containing 3A is a novel anti-apoptotic factor in lung adenocarcinoma cells

Fluorescence Microscopy / Membrane Proteins / Immunohistochemistry / Mitochondria / Apoptosis / Biological Sciences / Humans / Female / Drug Resistance / Male / Cisplatin / HeLa cells / Disease Progression / Adenocarcinoma / Biological Sciences / Humans / Female / Drug Resistance / Male / Cisplatin / HeLa cells / Disease Progression / Adenocarcinoma

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Overexpression of optic atrophy 1 protein increases cisplatin resistance via inactivation of caspase-dependent apoptosis in lung adenocarcinoma cells

Apoptosis / Caspases / Humans / Taiwan / Female / Drug Resistance / Male / Cytochrome C / Clinical Sciences / Cisplatin / Survival Rate / Human Pathology / Antineoplastic Agents / Adenocarcinoma / Drug Resistance / Male / Cytochrome C / Clinical Sciences / Cisplatin / Survival Rate / Human Pathology / Antineoplastic Agents / Adenocarcinoma

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Extensively Drug-Resistant Mycobacterium tuberculosis from Aspirates, Rural South Africa

Medical Microbiology / Emerging Infectious Diseases / South Africa / Humans / Mycobacterium tuberculosis / Female / Drug Resistance / Male / Clinical Sciences / Adult / Public health systems and services research / Microbial Sensitivity Tests / Culture Media / Pleural Effusion / Lymph nodes / Female / Drug Resistance / Male / Clinical Sciences / Adult / Public health systems and services research / Microbial Sensitivity Tests / Culture Media / Pleural Effusion / Lymph nodes

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Confronting parasites from Canada

Genetics / Leishmania / Biological Sciences / Canada / Humans / TRENDS / Animals / Drug Resistance / Parasites / Fasciola hepatica / Interleukins / Entamoeba histolytica / Parasitic Diseases / Anthelmintics / Drug Targeting / Helminthiasis / Gene Expression Regulation / Host Defense / TRENDS / Animals / Drug Resistance / Parasites / Fasciola hepatica / Interleukins / Entamoeba histolytica / Parasitic Diseases / Anthelmintics / Drug Targeting / Helminthiasis / Gene Expression Regulation / Host Defense

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Pseudohypoaldosteronism due to renal and multisystem resistance to mineralocorticoids respond differently to carbenoxolone

Genetics / Diet / Cortisol / Humans / Child / Kidney / Aldosterone / Renin Angiotensin Aldosterone System / Female / Drug Resistance / Male / Polymerase Chain Reaction / Infant / Newborn Infant / Spectrum / Biochemistry and cell biology / Kidney / Aldosterone / Renin Angiotensin Aldosterone System / Female / Drug Resistance / Male / Polymerase Chain Reaction / Infant / Newborn Infant / Spectrum / Biochemistry and cell biology

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IMP - GMP specific cytosolic 5\'-nucleotidase regulates nucleotide pool and prodrug metabolism

Biological Sciences / Prodrugs / Humans / Drug Resistance / Physical sciences / Phosphorylation / Substrate Specificity / Cell Survival / Antineoplastic Agents / Nucleotides / Immunoblotting / Phosphorylation / Substrate Specificity / Cell Survival / Antineoplastic Agents / Nucleotides / Immunoblotting

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Cytosolic 5′-nucleotidase/nucleoside phosphotransferase: a single assay for a bifunctional enzyme

Methods / Cell line / Mutation / Animals / Drug Resistance / Male / Biochemical Toxicology / Phosphorylation / High Pressure Liquid Chromatography / Cattle / Biotransformation / Human Fibroblasts / Glycosyl Hydrolases / Biochemistry and cell biology / Adenosine Triphosphate / Male / Biochemical Toxicology / Phosphorylation / High Pressure Liquid Chromatography / Cattle / Biotransformation / Human Fibroblasts / Glycosyl Hydrolases / Biochemistry and cell biology / Adenosine Triphosphate

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NF-?B kinetics predetermine TNF-? sensitivity of colorectal cancer cells

Kinetics / Apoptosis / Gene expression / Humans / Drug Resistance / NF-kappa B / Clinical Sciences / Tumor necrosis factor-alpha / Transfection / DNA binding proteins / NF-kappa B / Clinical Sciences / Tumor necrosis factor-alpha / Transfection / DNA binding proteins

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A Reprofiled Drug, Auranofin, Is Effective against Metronidazole-Resistant Giardia lamblia

Microbiology / Medical Microbiology / Enzyme Inhibitors / Oxidative Stress / Humans / Mice / Animals / Drug Resistance / Oxidoreductases / Giardiasis / DRUG REPOSITIONING / Dysentery / Metronidazole / Mice / Animals / Drug Resistance / Oxidoreductases / Giardiasis / DRUG REPOSITIONING / Dysentery / Metronidazole

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Drug resistance associated genetic polymorphisms in Plasmodium falciparum and Plasmodium vivax collected in Honduras, Central America

Medical Microbiology / Malaria / Humans / Honduras / Drug Resistance / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Chloroquine / Plasmodium Vivax / Primaquine / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Chloroquine / Plasmodium Vivax / Primaquine

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Protein kinase Cη activates NF-κB in response to camptothecin-induced DNA damage

DNA damage / Humans / Adaptive Immunity / Drug Resistance / Cell Death / NF-kappa B / Transcription Factor / Cell nucleus / Camptothecin / Protein Kinase / Biochemistry and cell biology / Anticancer Drug / NF-kappa B / Transcription Factor / Cell nucleus / Camptothecin / Protein Kinase / Biochemistry and cell biology / Anticancer Drug

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Eosin B as a Novel Antimalarial Agent for Drug-Resistant Plasmodium falciparum

Microbiology / Medical Microbiology / Cell Culture / Toxoplasma gondii / Cell line / Humans / Animals / Drug Resistance / Life Cycle / Enzyme / Mode of action / Research Needs / Active site / Thioredoxin / Plasmodium falciparum / Antimalarials / Antimicrobial agents / Multienzyme complexes / Human Fibroblasts / Glutathione Reductase / Thioredoxin reductase / Dihydrofolate Reductase / Humans / Animals / Drug Resistance / Life Cycle / Enzyme / Mode of action / Research Needs / Active site / Thioredoxin / Plasmodium falciparum / Antimalarials / Antimicrobial agents / Multienzyme complexes / Human Fibroblasts / Glutathione Reductase / Thioredoxin reductase / Dihydrofolate Reductase

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Cytosolic 5′-nucleotidase/nucleoside phosphotransferase: a single assay for a bifunctional enzyme

Methods / Cell line / Mutation / Animals / Drug Resistance / Male / Biochemical Toxicology / Phosphorylation / Enzyme / High Pressure Liquid Chromatography / Cattle / Biotransformation / Human Fibroblasts / Glycosyl Hydrolases / Biochemistry and cell biology / Adenosine Triphosphate / Male / Biochemical Toxicology / Phosphorylation / Enzyme / High Pressure Liquid Chromatography / Cattle / Biotransformation / Human Fibroblasts / Glycosyl Hydrolases / Biochemistry and cell biology / Adenosine Triphosphate

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