Drug Targeting

Structural genomics of Mycobacterium tuberculosis: a preliminary report of progress at UCLA

Structural Biology / Genomics / Proteomics / Biophysical Chemistry / Structural Genomics / Protein Targeting / Biological Sciences / Glutamate / Tuberculosis / Mycobacterium tuberculosis / Physical sciences / Drug Design / Drug Delivery Systems / CHEMICAL SCIENCES / Thioredoxin / Protein Conformation / Drug Targeting / Structure Determination / Protein Targeting / Biological Sciences / Glutamate / Tuberculosis / Mycobacterium tuberculosis / Physical sciences / Drug Design / Drug Delivery Systems / CHEMICAL SCIENCES / Thioredoxin / Protein Conformation / Drug Targeting / Structure Determination

Comparative structural analysis of two proteins belonging to quorum sensing system in Vibrio cholerae

Biofilms / Molecular Dynamics Simulation / Signal Transduction / Communication System / Homology Modeling / Vibrio cholerae / Drug Design / Quorum Sensing / Molecular docking / Structure Analysis / Protein Binding / Drug Targeting / Molecular Dynamic Simulation / Environmental Parameter / Computational Method / Biochemistry and cell biology / Vibrio cholerae / Drug Design / Quorum Sensing / Molecular docking / Structure Analysis / Protein Binding / Drug Targeting / Molecular Dynamic Simulation / Environmental Parameter / Computational Method / Biochemistry and cell biology

Plasmodium falciparum signal peptide peptidase is a promising drug target against blood stage malaria

Gene Silencing / Humans / Animals / Drug Design / Biochemical / Protease Inhibitors / Presenilins / Plasmodium falciparum / Antimalarials / Protein Conformation / Amino Acid Sequence / Erythrocytes / Drug Targeting / Carbamates / Biochemistry and cell biology / Protease Inhibitors / Presenilins / Plasmodium falciparum / Antimalarials / Protein Conformation / Amino Acid Sequence / Erythrocytes / Drug Targeting / Carbamates / Biochemistry and cell biology

Albumin-based nanoparticles as potential controlled release drug delivery systems

Biomedical Engineering / Self Assembly / Drug delivery / Nanoparticles / Drug Delivery System / Humans / Controlled release / Albumin / Surface modification / Animals / Surface Properties / Side Effect / Spray Drying / Drug Targeting / Drug Carriers / Delayed-Action Preparations / Humans / Controlled release / Albumin / Surface modification / Animals / Surface Properties / Side Effect / Spray Drying / Drug Targeting / Drug Carriers / Delayed-Action Preparations

Mitochondrial pharmaceutics

Genetics / Arsenic / Gene Therapy / Drug delivery / Ischemia Reperfusion Injury / Mitochondrial dysfunction / Neuromuscular Disease / Biological activity / Drug Targeting / Mitochondrion / Mitochondrial dysfunction / Neuromuscular Disease / Biological activity / Drug Targeting / Mitochondrion

Mitochondrial pharmaceutics

Genetics / Arsenic / Gene Therapy / Drug delivery / Ischemia Reperfusion Injury / Mitochondrial dysfunction / Neuromuscular Disease / Biological activity / Drug Targeting / Mitochondrion / Mitochondrial dysfunction / Neuromuscular Disease / Biological activity / Drug Targeting / Mitochondrion

Structural genomics of Mycobacterium tuberculosis: a preliminary report of progress at UCLA

Structural Biology / Genomics / Proteomics / Biophysical Chemistry / Structural Genomics / Protein Targeting / Biological Sciences / Glutamate / Tuberculosis / Mycobacterium tuberculosis / Physical sciences / Drug Design / Drug Delivery Systems / CHEMICAL SCIENCES / Thioredoxin / Protein Conformation / Drug Targeting / Structure Determination / Protein Targeting / Biological Sciences / Glutamate / Tuberculosis / Mycobacterium tuberculosis / Physical sciences / Drug Design / Drug Delivery Systems / CHEMICAL SCIENCES / Thioredoxin / Protein Conformation / Drug Targeting / Structure Determination

Atypical (RIO) protein kinases from Haemonchus contortus — Promise as new targets for nematocidal drugs

Engineering / Technology / Caenorhabditis elegans / Biotechnology / Biological Sciences / Protein Kinases / Animals / Small Ruminant Production / Protein Kinase / Anthelmintics / Drug Targeting / Haemonchus / Protein Kinases / Animals / Small Ruminant Production / Protein Kinase / Anthelmintics / Drug Targeting / Haemonchus

Serine/threonine phosphatases in socioeconomically important parasitic nematodes—Prospects as novel drug targets?

Engineering / Bioinformatics / Technology / Molecular Biology / Genomics / Biotechnology / Biological Sciences / Humans / Parasite / Resistance / Animals / Drug Resistance / Parasites / Genome / Nematoda / Amino Acid Sequence / Drug Targeting / Molecular Sequence Data / Biotechnology / Biological Sciences / Humans / Parasite / Resistance / Animals / Drug Resistance / Parasites / Genome / Nematoda / Amino Acid Sequence / Drug Targeting / Molecular Sequence Data

Serine/threonine phosphatases in socioeconomically important parasitic nematodes – prospects as novel drug targets?

Engineering / Bioinformatics / Technology / Molecular Biology / Genomics / Biotechnology / Biological Sciences / Humans / Parasite / Resistance / Animals / Drug Resistance / Parasites / Genome / Nematoda / Amino Acid Sequence / Drug Targeting / Molecular Sequence Data / Biotechnology / Biological Sciences / Humans / Parasite / Resistance / Animals / Drug Resistance / Parasites / Genome / Nematoda / Amino Acid Sequence / Drug Targeting / Molecular Sequence Data

Control of apoptosis of cardiovascular fibroblasts: A novel drug target

Apoptosis / Humans / Fibrosis / Programmed cell death / Anticoagulants / Heart Disease / Clinical Sciences / Myocardium / Growth Factor / Drug Targeting / Cell Survival / Gene Transfer / Heart Diseases / Vascular Smooth Muscle / Heart Disease / Clinical Sciences / Myocardium / Growth Factor / Drug Targeting / Cell Survival / Gene Transfer / Heart Diseases / Vascular Smooth Muscle

Toxoplasma gondii aspartic protease 1 is not essential in tachyzoites

Microbiology / Toxoplasma / Toxoplasma gondii / Experimental parasitology / Cercopithecus aethiops / Humans / Secretory Pathway / Animals / Virulence factor / Veterinary Sciences / Drug Targeting / Vero cells / Humans / Secretory Pathway / Animals / Virulence factor / Veterinary Sciences / Drug Targeting / Vero cells

HIV aspartyl protease inhibitors as promising compounds against Candida albicans André Luis Souza dos Santos

Immune response / Cellular differentiation / Candida albicans / Drug Targeting

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