Enzyme Inhibitors

Peroxynitrite enhances astrocytic volume-sensitive excitatory amino acid release via a src tyrosine kinase-dependent mechanism

Neurochemistry / Enzyme Inhibitors / Ion Channels / Animals / Astrocyte / Astrocytes / Superoxide Dismutase / Rats / Neurosciences / Excitatory Amino Acids / Adenosine Triphosphate / Cell Size / Nitric oxide donors / Tyrosine Kinase / Astrocytes / Superoxide Dismutase / Rats / Neurosciences / Excitatory Amino Acids / Adenosine Triphosphate / Cell Size / Nitric oxide donors / Tyrosine Kinase

UDP-Glucuronosyltransferase inhibitors

Enzyme Inhibitors / Humans / Pesticides / Drug Design / Detoxification

A single sequence change destabilizes the influenza virus neuraminidase tetramer

Electron Microscopy / Kinetics / Medical Microbiology / Virology / Crystallization / Enzyme Inhibitors / Macromolecular X-Ray Crystallography / Influenza virus / Biological Sciences / X Rays / Glutamate / Humans / Computer Simulation / Animals / Electron Density / Enzyme / Neuraminidase / Active site / Protein Secondary Structure Prediction / Substrate Specificity / influenza A virus / Amino Acid Profile / Antiviral / Guanidines / Enzymatic Activity / Sialic Acids / Dimerization / Zanamivir / Electron Microscope / Enzyme Inhibitors / Macromolecular X-Ray Crystallography / Influenza virus / Biological Sciences / X Rays / Glutamate / Humans / Computer Simulation / Animals / Electron Density / Enzyme / Neuraminidase / Active site / Protein Secondary Structure Prediction / Substrate Specificity / influenza A virus / Amino Acid Profile / Antiviral / Guanidines / Enzymatic Activity / Sialic Acids / Dimerization / Zanamivir / Electron Microscope

Polyphenol Oxidase Inhibitor from Blue Mussel ( Mytilus edulis ) Extract

Chemical Engineering / Food Science / Enzyme Inhibitors / Animals / Fruit / Vegetables / High Pressure Liquid Chromatography / Malus / Mytilus edulis / Food Sciences / Solanum Tuberosum / Vegetables / High Pressure Liquid Chromatography / Malus / Mytilus edulis / Food Sciences / Solanum Tuberosum

In Vitro Activity of LK-157, a Novel Tricyclic Carbapenem As Broad-Spectrum  -Lactamase Inhibitor

Microbiology / Medical Microbiology / Enzyme Inhibitors / Infectious Disease / Bacteria / Enzyme / Spectrum / Anti-Bacterial Agents / Carbapenems / Microbial Sensitivity Tests / Amino Acid Profile / Enzyme / Spectrum / Anti-Bacterial Agents / Carbapenems / Microbial Sensitivity Tests / Amino Acid Profile

In Vitro Activity of LK-157, a Novel Tricyclic Carbapenem As Broad-Spectrum  -Lactamase Inhibitor

Microbiology / Medical Microbiology / Enzyme Inhibitors / Infectious Disease / Bacteria / Enzyme / Spectrum / Anti-Bacterial Agents / Carbapenems / Microbial Sensitivity Tests / Amino Acid Profile / Enzyme / Spectrum / Anti-Bacterial Agents / Carbapenems / Microbial Sensitivity Tests / Amino Acid Profile

Analogs of natural aminoacyl-tRNA synthetase inhibitors clear malaria in vivo

Enzyme Inhibitors / Multidisciplinary / Humans / Mice / Animals / Plasmodium falciparum / Antimalarials / Plasmodium falciparum / Antimalarials

Antrodia camphorata prevents rat pheochromocytoma cells from serum deprivation-induced apoptosis

Enzyme Inhibitors / Apoptosis / Gene expression / Protein synthesis / Biological Sciences / Taiwan / Animals / Phosphorylation / Pheochromocytoma / Transcription Factor / Rats / Traditional East Asian medicine / Taiwan / Animals / Phosphorylation / Pheochromocytoma / Transcription Factor / Rats / Traditional East Asian medicine

Novel cell death program leads to neutrophil extracellular traps

Electron Microscopy / Enzyme Inhibitors / Cell Biology / Innate immunity / Apoptosis / Biological Sciences / Antibodies / Humans / Reactive Oxygen Species / Cell Death / Staphylococcus aureus / Catalase / NADPH oxidase / Chromatin / Hydrogen Peroxide / Neutrophils / Nuclear envelope / Phagocytosis / Experimental Medicine / The cell / Cell Survival / Biological Sciences / Antibodies / Humans / Reactive Oxygen Species / Cell Death / Staphylococcus aureus / Catalase / NADPH oxidase / Chromatin / Hydrogen Peroxide / Neutrophils / Nuclear envelope / Phagocytosis / Experimental Medicine / The cell / Cell Survival

Efeito do lipopolissacarídio bacteriano sobre o esvaziamento gástrico de ratos: avaliação do pré-tratamento com Nw-nitro-L-arginine methyl ester (L-NAME)

Enzyme Inhibitors / Lipopolysaccharide / Dexamethasone / Escherichia coli / Nitric oxide / Animals / Male / Urea / Methylene Blue / Lipopolysaccharides / Rats / Nitric Oxide Synthase / Analysis of Variance / Wistar Rats / Nephrectomy / Creatinine / Gastric Emptying / Animals / Male / Urea / Methylene Blue / Lipopolysaccharides / Rats / Nitric Oxide Synthase / Analysis of Variance / Wistar Rats / Nephrectomy / Creatinine / Gastric Emptying

Efeito do lipopolissacarídio bacteriano sobre o esvaziamento gástrico de ratos: avaliação do pré-tratamento com dexametasona e azul de metileno

Enzyme Inhibitors / Lipopolysaccharide / Dexamethasone / Escherichia coli / Nitric oxide / Animals / Male / Urea / Methylene Blue / Lipopolysaccharides / Rats / Nitric Oxide Synthase / Analysis of Variance / Wistar Rats / Nephrectomy / Creatinine / Gastric Emptying / Animals / Male / Urea / Methylene Blue / Lipopolysaccharides / Rats / Nitric Oxide Synthase / Analysis of Variance / Wistar Rats / Nephrectomy / Creatinine / Gastric Emptying

Cellular defense against H2O2-induced apoptosis via MAP kinase–MKP-1 pathway

Free Radicals / Enzyme Inhibitors / Oxidative Stress / Apoptosis / Western blotting / Signal Transduction / Reactive Oxygen Species / Animals / Male / Protein tyrosine phosphatase / Hydrogen Peroxide / Rats / Time Factors / Western blot / Transfection / Growth Factor / Cell Cycle Proteins / MAP Kinase / Protein Tyrosine Phosphatases / Oxidants / Biochemistry and cell biology / Signal Transduction / Reactive Oxygen Species / Animals / Male / Protein tyrosine phosphatase / Hydrogen Peroxide / Rats / Time Factors / Western blot / Transfection / Growth Factor / Cell Cycle Proteins / MAP Kinase / Protein Tyrosine Phosphatases / Oxidants / Biochemistry and cell biology

Tropolysin, a New Oligopeptidase from African Trypanosomes † , ‡

Biochemistry / Africa / Enzyme Inhibitors / Phylogeny / Humans / Sequence alignment / Animals / Peptides / Cattle / Trypanosoma brucei brucei / Protozoan Proteins / Amino Acid Sequence / Biochemistry and cell biology / Sequence alignment / Animals / Peptides / Cattle / Trypanosoma brucei brucei / Protozoan Proteins / Amino Acid Sequence / Biochemistry and cell biology

3-Amino-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: A new class of CDK2 inhibitors

Organic Chemistry / Enzyme Inhibitors / Macromolecular X-Ray Crystallography / Humans / Bioorganic and medicinal Chemistry / Cell Proliferation / Pyrazoles / Aurora kinases / Structure activity Relationship / Antineoplastic Agents / Molecular Structure / Cell Proliferation / Pyrazoles / Aurora kinases / Structure activity Relationship / Antineoplastic Agents / Molecular Structure

NADPH Oxidase Plays a Central Role in Blood-Brain Barrier Damage in Experimental Stroke

Enzyme Inhibitors / Clostridium difficile / Stroke / Endothelial Cells / Reactive Oxygen Species / Mice / Blood brain barrier / Animals / Male / Electrical Resistance / Actin Cytoskeleton / Brain injury / Mitogen Activated Protein Kinase / NADPH oxidase / Clinical Sciences / Endothelial cell / Cerebral Ischemia / Rho-kinase / Reperfusion injury / Sus Scrofa / Ischemia–reperfusion / Neurosciences / Brain Edema / Middle Cerebral Artery / Protein Transport / Mice / Blood brain barrier / Animals / Male / Electrical Resistance / Actin Cytoskeleton / Brain injury / Mitogen Activated Protein Kinase / NADPH oxidase / Clinical Sciences / Endothelial cell / Cerebral Ischemia / Rho-kinase / Reperfusion injury / Sus Scrofa / Ischemia–reperfusion / Neurosciences / Brain Edema / Middle Cerebral Artery / Protein Transport

Glycyrrhizic acid (GCA) as 11β-hydroxysteroid dehydrogenase inhibitor exerts protective effect against glucocorticoid-induced osteoporosis

Immunohistochemistry / Enzyme Inhibitors / Dexamethasone / Osteoporosis / Animals / Corticosterone / Male / Dietary Supplements / Bone Mineral Metabolism / Osteocalcin / Clinical Sciences / Amino Acids / Rats / Bone and Bones / Glucocorticoids / Adrenalectomy / Biochemistry and cell biology / Biomechanical Phenomena / Corticosterone / Male / Dietary Supplements / Bone Mineral Metabolism / Osteocalcin / Clinical Sciences / Amino Acids / Rats / Bone and Bones / Glucocorticoids / Adrenalectomy / Biochemistry and cell biology / Biomechanical Phenomena
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