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Enzyme Inhibitors
Enzyme Inhibitors
Regulation of System A Amino Acid Transport in 3T3-L1 Adipocytes by Insulin
Kinetics / Enzyme Inhibitors / Biological Chemistry / Signal Transduction / Biological Sciences / Insulin / Mice / Animals / T cells / CHEMICAL SCIENCES / Amino Acids / Adipocytes / Chromones / Insulin / Mice / Animals / T cells / CHEMICAL SCIENCES / Amino Acids / Adipocytes / Chromones
Drug-resistant breast carcinoma (MCF-7) cells are paradoxically sensitive to apoptosis
Enzyme Inhibitors / Mitochondria / Apoptosis / Western blotting / Caspases / Cellular / Humans / Female / Drug Resistance / Cellular Physiology / Medical Physiology / Caspase / Doxorubicin / Carcinoma / Breast carcinoma / Staurosporine / Cellular / Humans / Female / Drug Resistance / Cellular Physiology / Medical Physiology / Caspase / Doxorubicin / Carcinoma / Breast carcinoma / Staurosporine
OXA-18, a class D clavulanic acid-inhibited extended-spectrum beta-lactamase from Pseudomonas aeruginosa
Microbiology / Kinetics / Medical Microbiology / Enzyme Inhibitors / Nucleic acid hybridization / Plasmids / Pseudomonas aeruginosa / Enzyme / Molecular cloning / Spectrum / Gram-negative bacteria / Genomic DNA / Microbial Sensitivity Tests / Amino Acid Profile / Molecular Mass / Pseudomonas Aeruginosa / Molecular weight / Amino Acid Sequence / Base Sequence / Beta Lactamases / Plasmids / Pseudomonas aeruginosa / Enzyme / Molecular cloning / Spectrum / Gram-negative bacteria / Genomic DNA / Microbial Sensitivity Tests / Amino Acid Profile / Molecular Mass / Pseudomonas Aeruginosa / Molecular weight / Amino Acid Sequence / Base Sequence / Beta Lactamases
Disulfiram is a potent modulator of multidrug transporter Cdr1p of Candida albicans
Enzyme Inhibitors / Biophysical Chemistry / Drug Use / Saccharomyces cerevisiae / Multidrug Resistance / Drug Resistance / Candidiasis / Candida albicans / Membrane transport proteins / Molecular cloning / Antifungal Agents / Binding Site / Disulfiram / Biochemistry and cell biology / Adenosine Triphosphate / Drug Resistance / Candidiasis / Candida albicans / Membrane transport proteins / Molecular cloning / Antifungal Agents / Binding Site / Disulfiram / Biochemistry and cell biology / Adenosine Triphosphate
Novel pyrazolopyrimidine derivatives as GSK-3 inhibitors
Organic Chemistry / Enzyme Inhibitors / Tight Binding / Bioorganic and medicinal Chemistry / Pyrazoles
Cellular defense against H2O2-induced apoptosis via MAP kinase–MKP-1 pathway
Free Radicals / Enzyme Inhibitors / Oxidative Stress / Apoptosis / Western blotting / Signal Transduction / Reactive Oxygen Species / Animals / Male / Protein tyrosine phosphatase / Hydrogen Peroxide / Rats / Time Factors / Western blot / Transfection / Growth Factor / Cell Cycle Proteins / MAP Kinase / Protein Tyrosine Phosphatases / Oxidants / Biochemistry and cell biology / Signal Transduction / Reactive Oxygen Species / Animals / Male / Protein tyrosine phosphatase / Hydrogen Peroxide / Rats / Time Factors / Western blot / Transfection / Growth Factor / Cell Cycle Proteins / MAP Kinase / Protein Tyrosine Phosphatases / Oxidants / Biochemistry and cell biology
Phosphoramidate Dinucleosides as Hepatitis C Virus Polymerase Inhibitors
Organic Chemistry / Medicinal Chemistry / Modeling / Enzyme Inhibitors / Magnetic Resonance Spectroscopy / In Vitro / Humans / Virus / Hepatitis C Virus / Organophosphorus Compounds / Medicinal / Molecular Model / Nucleosides / Chemical Synthesis / Oxidation-Reduction / In Vitro / Humans / Virus / Hepatitis C Virus / Organophosphorus Compounds / Medicinal / Molecular Model / Nucleosides / Chemical Synthesis / Oxidation-Reduction
Phosphoramidate Dinucleosides as Hepatitis C Virus Polymerase Inhibitors
Organic Chemistry / Medicinal Chemistry / Modeling / Enzyme Inhibitors / Magnetic Resonance Spectroscopy / In Vitro / Humans / Virus / Hepatitis C Virus / Organophosphorus Compounds / Medicinal / Molecular Model / Nucleosides / Chemical Synthesis / Oxidation-Reduction / In Vitro / Humans / Virus / Hepatitis C Virus / Organophosphorus Compounds / Medicinal / Molecular Model / Nucleosides / Chemical Synthesis / Oxidation-Reduction
PARP Inhibitors as P-glyoprotein Substrates
Enzyme Inhibitors / Humans / Pharmaceutical Sciences / P-glycoprotein
Asymmetric membrane ganglioside sialidase activity specifies axonal fate
Neuroscience / Physiology / Cognitive Science / Psychophysics / Molecular Biology / Behavior / Enzyme Inhibitors / Systems Neuroscience / Nature / Signal Transduction / Learning / Memory / Computation / Cell Differentiation / Model / Animals / Functional Imaging / Cortex / Nature Neuroscience / Cell Polarity / Central Nervous System / Dendrites / Neuraminidase / Rats / Enzymatic Activity / Neurosciences / Plasma Membrane / Behavior / Enzyme Inhibitors / Systems Neuroscience / Nature / Signal Transduction / Learning / Memory / Computation / Cell Differentiation / Model / Animals / Functional Imaging / Cortex / Nature Neuroscience / Cell Polarity / Central Nervous System / Dendrites / Neuraminidase / Rats / Enzymatic Activity / Neurosciences / Plasma Membrane
Irbic acid, a dicaffeoylquinic acid derivative from Centella asiatica cell cultures
Complementary and Alternative Medicine / Plant Biology / Mass Spectrometry / Enzyme Inhibitors / Magnetic Resonance Spectroscopy / Cell Culture / Antioxidant Activity / Plant extracts / Fitoterapia / Biological activity / Centella / Chlorogenic Acid / Quinic Acid / Molecular Structure / Cell Culture / Antioxidant Activity / Plant extracts / Fitoterapia / Biological activity / Centella / Chlorogenic Acid / Quinic Acid / Molecular Structure
α-Glucosidase inhibitory pentacyclic triterpenes from the stem bark of Fagara tessmannii (Rutaceae)
Phytochemistry / Enzyme Inhibitors / Magnetic Resonance Spectroscopy / Biological Sciences / STEM / CHEMICAL SCIENCES / Bark / Antibacterial activity / Isolation / Rutaceae / Fatty Acid / Phytosterols / Molecular Structure / Triterpenes / CHEMICAL SCIENCES / Bark / Antibacterial activity / Isolation / Rutaceae / Fatty Acid / Phytosterols / Molecular Structure / Triterpenes
A phosphoinositide 3-kinase-γ inhibitor, AS605240 prevents bleomycin-induced pulmonary fibrosis in rats
Enzyme Inhibitors / Lung Inflammation / Pulmonary fibrosis / Female / Animals / Inflammatory disease / Rats / Western blot / Bleomycin / Biochemistry and cell biology / Inflammatory disease / Rats / Western blot / Bleomycin / Biochemistry and cell biology
Novel IKK inhibitors: beta-carbolines
Organic Chemistry / Enzyme Inhibitors / Western blotting / Humans / HeLa cells / Bioorganic and medicinal Chemistry / Structure activity Relationship / Bioorganic and medicinal Chemistry / Structure activity Relationship
Novel IKK inhibitors: beta-carbolines
Organic Chemistry / Enzyme Inhibitors / Western blotting / Humans / HeLa cells / Bioorganic and medicinal Chemistry / Structure activity Relationship / Bioorganic and medicinal Chemistry / Structure activity Relationship
α-Glucosidase inhibitory pentacyclic triterpenes from the stem bark of Fagara tessmannii (Rutaceae)
Phytochemistry / Enzyme Inhibitors / Magnetic Resonance Spectroscopy / Biological Sciences / STEM / CHEMICAL SCIENCES / Bark / Antibacterial activity / Isolation / Rutaceae / Fatty Acid / Phytosterols / Molecular Structure / Triterpenes / CHEMICAL SCIENCES / Bark / Antibacterial activity / Isolation / Rutaceae / Fatty Acid / Phytosterols / Molecular Structure / Triterpenes
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