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Gene Silencing
Gene Silencing
Plasmodium falciparum signal peptide peptidase is a promising drug target against blood stage malaria
Gene Silencing / Humans / Animals / Drug Design / Biochemical / Protease Inhibitors / Plasmodium falciparum / Antimalarials / Protein Conformation / Amino Acid Sequence / Erythrocytes / Drug Targeting / Carbamates / Biochemistry and cell biology / Protease Inhibitors / Plasmodium falciparum / Antimalarials / Protein Conformation / Amino Acid Sequence / Erythrocytes / Drug Targeting / Carbamates / Biochemistry and cell biology
Tissue factor pathway inhibitor-2 as a frequently silenced tumor suppressor gene in hepatocellular carcinoma
Immunohistochemistry / Gene Silencing / Hepatology / Humans / Hepatocellular Carcinoma / DNA methylation / Glycoproteins / Clinical Sciences / Neoplasm Invasiveness / Tumor Suppressor Gene / Cell Proliferation / Hydroxamic Acids / Gene expression profiling / Histone deacetylase inhibitors / DNA methylation / Glycoproteins / Clinical Sciences / Neoplasm Invasiveness / Tumor Suppressor Gene / Cell Proliferation / Hydroxamic Acids / Gene expression profiling / Histone deacetylase inhibitors
A temperature-controlled amplicon system derived from Plum pox potyvirus
Technology / Transformation / Control / Tobacco / Plant biotechnology / Gene Silencing / Biological Sciences / Temperature / Genetic transformation / Plant viruses / Defence Mechanisms / Genomes / Amplicon / Expression Vector / Viral Replication / Gene Silencing / Biological Sciences / Temperature / Genetic transformation / Plant viruses / Defence Mechanisms / Genomes / Amplicon / Expression Vector / Viral Replication
A MicroRNA cluster at 14q32 drives aggressive lung adenocarcinoma
Gene Silencing / Humans / Female / Male / Cluster Analysis / Follow-up studies / Lung / Aged / Middle Aged / microRNAs / Neoplasm Invasiveness / Survival Rate / Prognosis / Gene expression profiling / Case Control Studies / Cohort Studies / Follow-up studies / Lung / Aged / Middle Aged / microRNAs / Neoplasm Invasiveness / Survival Rate / Prognosis / Gene expression profiling / Case Control Studies / Cohort Studies
Tripartite siRNA micelles as controlled delivery systems for primary dendritic cells
Immune response / Drug development / Gene Silencing / Dendritic Cells / Transgenic Mice / Block Copolymer / RNA interference / Micelles / Mice / Endocytosis / Animals / Dendritic cell / Delivery System / Hydrogen-Ion Concentration / Block Copolymer / RNA interference / Micelles / Mice / Endocytosis / Animals / Dendritic cell / Delivery System / Hydrogen-Ion Concentration
HSP90 Inhibitor 17-AAG Selectively Eradicates Lymphoma Stem Cells
Cancer / Transcription Factors / Gene Silencing / Signal Transduction / Lymphoma / Acute Myeloid Leukemia / Humans / Mice / Animals / DNA binding proteins / Benzoquinones / Acute Myeloid Leukemia / Humans / Mice / Animals / DNA binding proteins / Benzoquinones
SiRNA-loaded multi-shell nanoparticles incorporated into a multilayered film as a reservoir for gene silencing
Biomaterials / Tissue Engineering / Scanning Electron Microscopy / Nanoparticles / Atomic Force Microscopy / Multidisciplinary / Gene Silencing / Humans / Surface modification / Osteocalcin / Osteopontin / Calcium Phosphate / Model System / Bone Formation / Biological activity / Osteoblasts / Multidisciplinary / Gene Silencing / Humans / Surface modification / Osteocalcin / Osteopontin / Calcium Phosphate / Model System / Bone Formation / Biological activity / Osteoblasts
CXCR7 Silencing Attenuates Cell Adaptive Response to Stromal Cell Derived Factor 1α after Hypoxia
Immunohistochemistry / Multidisciplinary / Gene Silencing / Western blotting / Hippocampus / Animals / Lentivirus / Neurons / PLoS one / Rats / Analysis of Variance / Time Factors / Neural Stem Cells / Enzyme Linked Immunosorbent Assay / Animals / Lentivirus / Neurons / PLoS one / Rats / Analysis of Variance / Time Factors / Neural Stem Cells / Enzyme Linked Immunosorbent Assay
NUMB controls p53 tumour suppressor activity
Breast Cancer / Membrane Proteins / DNA damage / Multidisciplinary / Gene Silencing / Nature / Humans / Ubiquitin ligase / Prognosis / Cell Fate / Protein Binding / Plasma Membrane / Ubiquitination / Nature / Humans / Ubiquitin ligase / Prognosis / Cell Fate / Protein Binding / Plasma Membrane / Ubiquitination
NUMB controls p53 tumour suppressor activity
Breast Cancer / Membrane Proteins / DNA damage / Multidisciplinary / Gene Silencing / Nature / Humans / Ubiquitin ligase / Prognosis / Cell Fate / Protein Binding / Plasma Membrane / Ubiquitination / Nature / Humans / Ubiquitin ligase / Prognosis / Cell Fate / Protein Binding / Plasma Membrane / Ubiquitination
SiRNA-loaded multi-shell nanoparticles incorporated into a multilayered film as a reservoir for gene silencing
Biomaterials / Tissue Engineering / Scanning Electron Microscopy / Nanoparticles / Atomic Force Microscopy / Multidisciplinary / Gene Silencing / Humans / Surface modification / Osteocalcin / Osteopontin / Calcium Phosphate / Model System / Bone Formation / Biological activity / Osteoblasts / Multidisciplinary / Gene Silencing / Humans / Surface modification / Osteocalcin / Osteopontin / Calcium Phosphate / Model System / Bone Formation / Biological activity / Osteoblasts
Mitochondrial Transcription Factor B2 Is Essential for Metabolic Function in Drosophila melanogaster Development
Drosophila melanogaster / Mitochondria / Biological Chemistry / Apoptosis / Gene Silencing / Energy Metabolism / Biological Sciences / Longevity / Mitochondrial DNA / Animals / Biological / Glycolysis / Transcription Factor / CHEMICAL SCIENCES / Body Patterning / Oxidative phosphorylation / Larva / Body Weight / Cell Proliferation / Adenosine Triphosphate / Wing / Energy Metabolism / Biological Sciences / Longevity / Mitochondrial DNA / Animals / Biological / Glycolysis / Transcription Factor / CHEMICAL SCIENCES / Body Patterning / Oxidative phosphorylation / Larva / Body Weight / Cell Proliferation / Adenosine Triphosphate / Wing
VDAC1 selectively transfers apoptotic Ca2+ signals to mitochondria
Calcium / Mitochondria / Apoptosis / Gene Silencing / Biological Sciences / Humans / Calcium Signaling / Immunoprecipitation / Hydrogen Peroxide / HeLa cells / Protein isoforms / Cell Survival / Humans / Calcium Signaling / Immunoprecipitation / Hydrogen Peroxide / HeLa cells / Protein isoforms / Cell Survival
Plasmodium falciparum signal peptide peptidase is a promising drug target against blood stage malaria
Gene Silencing / Humans / Animals / Drug Design / Biochemical / Protease Inhibitors / Presenilins / Plasmodium falciparum / Antimalarials / Protein Conformation / Amino Acid Sequence / Erythrocytes / Drug Targeting / Carbamates / Biochemistry and cell biology / Protease Inhibitors / Presenilins / Plasmodium falciparum / Antimalarials / Protein Conformation / Amino Acid Sequence / Erythrocytes / Drug Targeting / Carbamates / Biochemistry and cell biology
Nuclear membranes control symbiotic calcium signaling of legumes
Symbiosis / Multidisciplinary / Ion Channels / Gene Silencing / Diffusion / Endoplasmic Reticulum / Calcium Signaling / Plant Roots / Nuclear envelope / Lipopolysaccharides / PLANT PROTEINS / Protein Transport / Plant Epidermis / Endoplasmic Reticulum / Calcium Signaling / Plant Roots / Nuclear envelope / Lipopolysaccharides / PLANT PROTEINS / Protein Transport / Plant Epidermis
A temperature-controlled amplicon system derived from Plum pox potyvirus
Technology / Transformation / Control / Tobacco / Plant biotechnology / Gene Silencing / Biological Sciences / Temperature / Genetic transformation / Plant viruses / Defence Mechanisms / Genomes / Amplicon / Expression Vector / Viral Replication / Plum Pox Virus / Gene Silencing / Biological Sciences / Temperature / Genetic transformation / Plant viruses / Defence Mechanisms / Genomes / Amplicon / Expression Vector / Viral Replication / Plum Pox Virus
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