Gene Therapy

Intra-arterial delivery of p53-containing adenoviral vector into experimental brain tumors

Oncology / Biotechnology / Cancer / Gene Therapy / Treatment Outcome / Brain Tumor / Humans / Glioma / Female / Animals / Rat Brain / Cancer Gene Therapy / Tumor Suppressor Gene / Rats / Survival Rate / Transgene Expression / Tumor Growth / Brain Neoplasms / Mannitol / Gene Transfer / Brain Tumor / Humans / Glioma / Female / Animals / Rat Brain / Cancer Gene Therapy / Tumor Suppressor Gene / Rats / Survival Rate / Transgene Expression / Tumor Growth / Brain Neoplasms / Mannitol / Gene Transfer

Cervical cancer isolate PT3, super-permissive for adeno-associated virus replication, over-expresses DNA polymerase δ, PCNA, RFC and RPA

Gene Therapy / DNA replication / Gene expression / Biological Sciences / Cell line / Humans / Keratinocytes / Female / Cell Death / Adeno-associated virus / Cervical Cancer / DNA Polymerase / Humans / Keratinocytes / Female / Cell Death / Adeno-associated virus / Cervical Cancer / DNA Polymerase

Localized Gene Expression Following Administration of Adeno-associated Viral Vectors via Pancreatic Ducts

Pharmacology / Technology / Gene Therapy / Immunohistochemistry / Gene expression / Biological Sciences / Molecular / Insulin / Mice / Pancreas / Female / Animals / Therapy / Adeno-associated virus / Plasmids / Rats / Time Factors / SURGICAL TECHNIQUE / Type 2 Diabetes Mellitus / Molecular Targeted Therapy / Enzyme Linked Immunosorbent Assay / Endoscopic Retrograde Cholangiopancreatography / Alpha-1 Antitrypsin / Gene Transfer / Gene Expression Regulation / Biological Sciences / Molecular / Insulin / Mice / Pancreas / Female / Animals / Therapy / Adeno-associated virus / Plasmids / Rats / Time Factors / SURGICAL TECHNIQUE / Type 2 Diabetes Mellitus / Molecular Targeted Therapy / Enzyme Linked Immunosorbent Assay / Endoscopic Retrograde Cholangiopancreatography / Alpha-1 Antitrypsin / Gene Transfer / Gene Expression Regulation

Nanoparticles, molecular biosensors, and multispectral confocal microscopy

RADIATION DAMAGE / Gene Therapy / Cell Biology / Nanotechnology / Confocal Microscopy / Quantum Dots / Molecular / RNA interference / Humans / Reactive Oxygen Species / Gene transfer techniques / Feedback Control / Single Cell / Clinical Sciences / Gene Delivery / Biocompatible Materials / Biosensing Techniques / Biochemistry and cell biology / Quantum Dots / Molecular / RNA interference / Humans / Reactive Oxygen Species / Gene transfer techniques / Feedback Control / Single Cell / Clinical Sciences / Gene Delivery / Biocompatible Materials / Biosensing Techniques / Biochemistry and cell biology

Expression of β-galactosidase in mouse brain: utilization of a novel nonreplicative Sindbis virus vector as a neuronal gene delivery system

Gene Therapy / Genome Size / Biological Sciences / Epitope mapping / Antigen Processing / Central Nervous System / Gene Delivery / Time Dependent / Sindbis virus / In Vitro Transcription / Central Nervous System / Gene Delivery / Time Dependent / Sindbis virus / In Vitro Transcription

Human neural stem cells overexpressing glial cell line-derived neurotrophic factor in experimental cerebral hemorrhage

Gene Therapy / Apoptosis / Stem Cell Transplantation / Biological Sciences / Cell Differentiation / Humans / Mice / Animals / Neurons / Cerebral Hemorrhage / Humans / Mice / Animals / Neurons / Cerebral Hemorrhage

Mitochondrial pharmaceutics

Genetics / Arsenic / Gene Therapy / Drug delivery / Ischemia Reperfusion Injury / Mitochondrial dysfunction / Neuromuscular Disease / Biological activity / Drug Targeting / Mitochondrion / Mitochondrial dysfunction / Neuromuscular Disease / Biological activity / Drug Targeting / Mitochondrion

Mitochondrial pharmaceutics

Genetics / Arsenic / Gene Therapy / Drug delivery / Ischemia Reperfusion Injury / Mitochondrial dysfunction / Neuromuscular Disease / Biological activity / Drug Targeting / Mitochondrion / Mitochondrial dysfunction / Neuromuscular Disease / Biological activity / Drug Targeting / Mitochondrion

Inhibition of cerebral ischemia/reperfusion-induced injury by adenovirus expressed C-terminal amino acids of GluR6

Cognitive Science / Gene Therapy / Membrane Proteins / Western blotting / Neuronal cell death / Signal Transduction / Brain / Animals / Gene transfer techniques / Male / Cell Death / Cell Fractionation / Phosphorylation / Brain Ischemia / Cytoprotection / Neurons / Brain injury / Mitogen Activated Protein Kinase / NMDA / AMPA / Rats / Neuronal Death / Analysis of Variance / Cerebral Ischemia / Amino Acid Profile / MAPK / Reperfusion injury / Subcellular Fractions / Cell Survival / Neurosciences / Postsynaptic Density / Ad / Signal Transduction / Brain / Animals / Gene transfer techniques / Male / Cell Death / Cell Fractionation / Phosphorylation / Brain Ischemia / Cytoprotection / Neurons / Brain injury / Mitogen Activated Protein Kinase / NMDA / AMPA / Rats / Neuronal Death / Analysis of Variance / Cerebral Ischemia / Amino Acid Profile / MAPK / Reperfusion injury / Subcellular Fractions / Cell Survival / Neurosciences / Postsynaptic Density / Ad

Vectores Lipidicos Nuevas Estrategias Aplicadas a La Terapia Genica

Gene Therapy / DNA / Medicina / Palabras Clave: BIM

Development of adenovirus serotype 35 as a gene transfer vector

Gene Therapy / Virology / Genetic Engineering / Biological Sciences / Cell line / Humans / Liver / Mice / Female / Animals / Gene transfer techniques / Bone marrow / Gene Delivery / Genome Organization / Cellular Immunity / Viral Infection / Cell Surface Markers / Neutralizing antibodies / Gene Transfer / Serotyping / Humans / Liver / Mice / Female / Animals / Gene transfer techniques / Bone marrow / Gene Delivery / Genome Organization / Cellular Immunity / Viral Infection / Cell Surface Markers / Neutralizing antibodies / Gene Transfer / Serotyping

From Disease Genes to Cellular Pathways: A Progress Report

Genetics / Metabolism / Gene Therapy / Retinal Pigment Epithelium / Gene expression / Functional Genomics / Phylogeny / Microarray Analysis / Degeneration / Retinal Diseases / DNA binding proteins / cDNA library / Functional Genomics / Phylogeny / Microarray Analysis / Degeneration / Retinal Diseases / DNA binding proteins / cDNA library

A novel technique to monitor carboxypeptidase G2 expression in suicide gene therapy using 19 F magnetic resonance spectroscopy

Biomedical Engineering / Kinetics / Gene Therapy / Pharmacokinetics / Magnetic Resonance Spectroscopy / Molecular Imaging / Prodrugs / Humans / Nmr / Clinical Sciences / Fluorine / Buffers / Solutions / Molecular Imaging / Prodrugs / Humans / Nmr / Clinical Sciences / Fluorine / Buffers / Solutions

Localized Gene Expression Following Administration of Adeno-associated Viral Vectors via Pancreatic Ducts

Pharmacology / Technology / Gene Therapy / Immunohistochemistry / Gene expression / Biological Sciences / Molecular / Insulin / Mice / Pancreas / Female / Animals / Therapy / Adeno-associated virus / Plasmids / Rats / Time Factors / SURGICAL TECHNIQUE / Type 2 Diabetes Mellitus / Molecular Targeted Therapy / Enzyme Linked Immunosorbent Assay / Endoscopic Retrograde Cholangiopancreatography / Alpha-1 Antitrypsin / Gene Transfer / Gene Expression Regulation / Biological Sciences / Molecular / Insulin / Mice / Pancreas / Female / Animals / Therapy / Adeno-associated virus / Plasmids / Rats / Time Factors / SURGICAL TECHNIQUE / Type 2 Diabetes Mellitus / Molecular Targeted Therapy / Enzyme Linked Immunosorbent Assay / Endoscopic Retrograde Cholangiopancreatography / Alpha-1 Antitrypsin / Gene Transfer / Gene Expression Regulation

Human Mesenchymal Stem Cells as a Gene Delivery System to Create Cardiac Pacemakers

Gap Junctions / Gene Therapy / Stem Cell / Ion Channels / Patch-clamp and imaging techniques / Dogs / Humans / Mice / Left Ventricular Assist Device / Electroporation / Animals / Heart rate / Acetylcholine / Clinical Sciences / Gene Delivery / Genetically Modified / Rats / Cesium / Delivery System / Circulation / Potassium Channels / Transfection / Ion Transport / Heart Ventricles / Mesenchymal Stromal Cells / Human Mesenchymal Stem Cells / Isoproterenol / Cholinergic agents / Dogs / Humans / Mice / Left Ventricular Assist Device / Electroporation / Animals / Heart rate / Acetylcholine / Clinical Sciences / Gene Delivery / Genetically Modified / Rats / Cesium / Delivery System / Circulation / Potassium Channels / Transfection / Ion Transport / Heart Ventricles / Mesenchymal Stromal Cells / Human Mesenchymal Stem Cells / Isoproterenol / Cholinergic agents

Emx2 as a novel tool to suppress glioblastoma

Gene Therapy / Glioblastoma Multiforme
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