Heterocyclic compounds

Cyclic urea derivatives as potent NK1 selective antagonists

Organic Chemistry / Macromolecular X-Ray Crystallography / Animals / Urea / Fluorine / Rats / Bioorganic and medicinal Chemistry / Structure activity Relationship / Protein Binding / Biological Availability / Heterocyclic compounds / Molecular Structure / Neurokinin receptor antagonists / Motor activity / Rats / Bioorganic and medicinal Chemistry / Structure activity Relationship / Protein Binding / Biological Availability / Heterocyclic compounds / Molecular Structure / Neurokinin receptor antagonists / Motor activity

Cyclic urea derivatives as potent NK1 selective antagonists

Organic Chemistry / Macromolecular X-Ray Crystallography / Animals / Urea / Fluorine / Rats / Bioorganic and medicinal Chemistry / Structure activity Relationship / Protein Binding / Biological Availability / Heterocyclic compounds / Molecular Structure / Neurokinin receptor antagonists / Motor activity / Rats / Bioorganic and medicinal Chemistry / Structure activity Relationship / Protein Binding / Biological Availability / Heterocyclic compounds / Molecular Structure / Neurokinin receptor antagonists / Motor activity

An aza-macrocycle containing maltolic side-arms (maltonis) as potential drug against human pediatric sarcomas

Cell Cycle / DNA damage / Apoptosis / Humans / Child / Mice / Animals / Sarcoma / Cell Proliferation / Antineoplastic Agents / Heterocyclic compounds / Mesenchymal Stromal Cells / Gene expression profiling / Mice / Animals / Sarcoma / Cell Proliferation / Antineoplastic Agents / Heterocyclic compounds / Mesenchymal Stromal Cells / Gene expression profiling

Human Melanoma Metastases Express Functional CXCR4

Immunohistochemistry / Western blotting / Chemokines and chemokine receptors / Humans / Melanoma / Skin / Mitogen Activated Protein Kinase / Fluorescent Antibody Technique / Time Factors / Cell Proliferation / Heterocyclic compounds / Skin / Mitogen Activated Protein Kinase / Fluorescent Antibody Technique / Time Factors / Cell Proliferation / Heterocyclic compounds

ChemInform Abstract: Room-Temperature Synthesis of ZIF-8: The Coexistence of ZnO Nanoneedles

Crystal Growth / Catalysis / Ionic Liquid / Energy Conversion / Temperature / Methane / Palladium / CHEMICAL SCIENCES / Room Temperature / Heterocyclic compounds / Molecular Structure / Methane / Palladium / CHEMICAL SCIENCES / Room Temperature / Heterocyclic compounds / Molecular Structure

ChemInform Abstract: Synthesis of a New Heterocyclic System - Pyrido[3′,2′:4,5]thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidine

Organic Chemistry / CHEMICAL SCIENCES / Cyclization / Biological Factors / Quaternary Ammonium Compounds / Cations / Heterocyclic compounds / Cations / Heterocyclic compounds

ChemInform Abstract: Room-Temperature Synthesis of ZIF-8: The Coexistence of ZnO Nanoneedles

Crystal Growth / Catalysis / Ionic Liquid / Energy Conversion / Temperature / Methane / Palladium / CHEMICAL SCIENCES / Room Temperature / Heterocyclic compounds / Molecular Structure / Methane / Palladium / CHEMICAL SCIENCES / Room Temperature / Heterocyclic compounds / Molecular Structure

Progenitor cell mobilizing treatments prevent experimental transplant arteriosclerosis

Polysaccharides / Hematopoietic Stem Cells / Mice / Animals / Vascular endothelium / Anticoagulants / Clinical Sciences / Molecular weight / Graft Rejection / Surgical / Aorta / Heterocyclic compounds / Simvastatin / Anticoagulants / Clinical Sciences / Molecular weight / Graft Rejection / Surgical / Aorta / Heterocyclic compounds / Simvastatin

SDF-1/CXCR4 blockade to mobilize hematopoietic progenitor cells from the placenta

Hematology / Stem Cell / Hematopoietic Stem Cells / Pregnancy / Humans / Placenta / Female / Bone marrow / Clinical Sciences / Bone Marrow Transplantation / Gestation / Heterocyclic compounds / Placenta / Female / Bone marrow / Clinical Sciences / Bone Marrow Transplantation / Gestation / Heterocyclic compounds

SDF-1/CXCR4 blockade to mobilize hematopoietic progenitor cells from the placenta

Hematology / Stem Cell / Hematopoietic Stem Cells / Pregnancy / Humans / Placenta / Female / Bone marrow / Clinical Sciences / Bone Marrow Transplantation / Gestation / Heterocyclic compounds / Placenta / Female / Bone marrow / Clinical Sciences / Bone Marrow Transplantation / Gestation / Heterocyclic compounds

A novel, broad-spectrum anticancer compound containing the imidazo[4,5-e][1,3]diazepine ring system

Organic Chemistry / Cytotoxicity / Ovarian Cancer / Cell line / In Vitro / Humans / Female / Male / Spectrum / Neoplasms / Biological activity / Ovary / Antitumor Activity / Structure activity Relationship / Chemical Synthesis / Antineoplastic Agents / Heterocyclic compounds / Humans / Female / Male / Spectrum / Neoplasms / Biological activity / Ovary / Antitumor Activity / Structure activity Relationship / Chemical Synthesis / Antineoplastic Agents / Heterocyclic compounds

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