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In Vitro
In Vitro
Síntese e avaliação da atividade antimicrobiana de novas 4-tiazolidinonas obtidas a partir de formilpiridina tiossemicarbazonas
In Vitro / CHEMICAL SCIENCES / Chemical Structure / Quimica Nova
Sensibilidade de Colletotrichum gloeosporioides (mancha manteigosa do cafeeiro) a diferentes concentrações de fungicidas
In Vitro / Fungicides / Colletotrichum gloeosporioides
Somatic embryogenesis of Myrciaria aureana (Brazilian grape tree)
Plant Biology / Culture / In Vitro / Light / Somatic Embryogenesis / Polyethylene Glycol / Activated Charcoal / In vitro culture / Embryos / Polyethylene Glycol / Activated Charcoal / In vitro culture / Embryos
Dimeric l-Dopa Derivatives as Potential Prodrugs
Organic Chemistry / Kinetics / In Vitro / Prodrugs / Humans / Animals / Plasma / Prodrug / Partition Coefficient / Levodopa / Shell Half-Life / Rats / Rat / Aqueous Solution / Hydrolysis / Chemical Stability / Drug Stability / Hydrogen-Ion Concentration / Chemical Synthesis / Physicochemical Properties / Dimerization / Enantiomer / Animals / Plasma / Prodrug / Partition Coefficient / Levodopa / Shell Half-Life / Rats / Rat / Aqueous Solution / Hydrolysis / Chemical Stability / Drug Stability / Hydrogen-Ion Concentration / Chemical Synthesis / Physicochemical Properties / Dimerization / Enantiomer
Naphthoquinoidal [1,2,3]-triazole, a new structural moiety active against Trypanosoma cruzi
Organic Chemistry / Treatment / Drug development / Macromolecular X-Ray Crystallography / In Vitro / Animals / Naphthoquinones / Chagas disease / European / Hydrogen Bonding / Trypanosoma Cruzi / Trypanocidal Agents / Triazoles / Structure activity Relationship / Cations / Chemical Synthesis / Molecular Structure / Animals / Naphthoquinones / Chagas disease / European / Hydrogen Bonding / Trypanosoma Cruzi / Trypanocidal Agents / Triazoles / Structure activity Relationship / Cations / Chemical Synthesis / Molecular Structure
Dammarane-Type Glycosides from Gynostemma pentaphyllum and Their Effects on IL-4-Induced Eotaxin Expression in Human Bronchial Epithelial Cells
Natural Products / Phytochemistry / Complementary and Alternative Medicine / Plant Biology / China / Pharmacognosy / Medicinal Plants / Vietnam / Gene expression / Structural Analysis / Biological Sciences / In Vitro / Humans / CHEMICAL SCIENCES / Chine / Chemokine / Isolation / Plant extracts / Epithelial cells / Natural / Biological activity / Glycosides / Molecular Structure / Triterpenes / Plant Leaves / Interleukin / Terpenoid / Pharmacognosy / Medicinal Plants / Vietnam / Gene expression / Structural Analysis / Biological Sciences / In Vitro / Humans / CHEMICAL SCIENCES / Chine / Chemokine / Isolation / Plant extracts / Epithelial cells / Natural / Biological activity / Glycosides / Molecular Structure / Triterpenes / Plant Leaves / Interleukin / Terpenoid
Nanoparticles as potential oral delivery systems of proteins and vaccines: A mechanistic approach
Physical Chemistry / Biomedical Engineering / Vaccines / Nanoparticle / Nanoparticles / Pharmaceutical Chemistry / In Vitro / Humans / Controlled release / Intestinal Mucosa / M Cells / Animals / Product Development / Drug Delivery Systems / Biodegradable Polymers / Proteins / Intestinal absorption / Oral Delivery / Biodegradable Polymer / Surface Properties / Gastrointestinal Tract / Biodegradability / Drug Release / Pharmaceutical Chemistry / In Vitro / Humans / Controlled release / Intestinal Mucosa / M Cells / Animals / Product Development / Drug Delivery Systems / Biodegradable Polymers / Proteins / Intestinal absorption / Oral Delivery / Biodegradable Polymer / Surface Properties / Gastrointestinal Tract / Biodegradability / Drug Release
Polyaspartylhydrazide Copolymer-Based Supramolecular Vesicular Aggregates as Delivery Devices for Anticancer Drugs
Engineering / Kinetics / Flow Cytometry / Polymers / Magnetic Resonance Spectroscopy / Cytotoxicity / Apoptosis / Biological Sciences / In Vitro / Humans / Peptides / Drug Delivery Systems / High Pressure Liquid Chromatography / CHEMICAL SCIENCES / Vesicle / Aqueous Solution / Drug Carriers / Biomacromolecules / Chemical Modification / Molecular Structure / Anticancer Drug / Cytotoxicity / Apoptosis / Biological Sciences / In Vitro / Humans / Peptides / Drug Delivery Systems / High Pressure Liquid Chromatography / CHEMICAL SCIENCES / Vesicle / Aqueous Solution / Drug Carriers / Biomacromolecules / Chemical Modification / Molecular Structure / Anticancer Drug
Análise multivariada da divergência genética de genótipos de arroz sob estresse salino durante a fase vegetativa
Genetic Diversity / In Vitro / Salinity / Rice / Genotypes
Discovery of novel inhibitors of Trypanosoma cruzi trans-sialidase from in silico screening
Organic Chemistry / Kinetics / Modeling / Crystallization / Enzyme Inhibitors / Pharmaceutical Chemistry / Macromolecular X-Ray Crystallography / Crystal structure / In Vitro / Virtual screening / Animals / Ligand Binding / Drug Design / Molecular docking / Glycoproteins / Chagas disease / Enzyme / Neuraminidase / Active site / Trypanosoma Cruzi / Ether / Molecular Model / Bioorganic and medicinal Chemistry / Sialic Acid / In Silico / Drug Targeting / Ligands / Trans-Sialidase / Pharmaceutical Chemistry / Macromolecular X-Ray Crystallography / Crystal structure / In Vitro / Virtual screening / Animals / Ligand Binding / Drug Design / Molecular docking / Glycoproteins / Chagas disease / Enzyme / Neuraminidase / Active site / Trypanosoma Cruzi / Ether / Molecular Model / Bioorganic and medicinal Chemistry / Sialic Acid / In Silico / Drug Targeting / Ligands / Trans-Sialidase
In vitro stage-specific chondrogenesis of mesenchymal stem cells committed to chondrocytes
Rheumatology / Immunology / Stem Cell / Gene expression / In Vitro / Cell Differentiation / Humans / Collagen / Mesenchymal Stem Cell / Arthritis / Clinical Sciences / Public health systems and services research / Guided Tissue Regeneration / Articular Cartilage Wear / Chondrocytes / Transforming Growth Factor Beta / Biological markers / Chondrogenesis / Cell Proliferation / Mesenchymal Stromal Cells / Extracellular Matrix Proteins / Cell Adhesion Molecules / Cell Differentiation / Humans / Collagen / Mesenchymal Stem Cell / Arthritis / Clinical Sciences / Public health systems and services research / Guided Tissue Regeneration / Articular Cartilage Wear / Chondrocytes / Transforming Growth Factor Beta / Biological markers / Chondrogenesis / Cell Proliferation / Mesenchymal Stromal Cells / Extracellular Matrix Proteins / Cell Adhesion Molecules
Atividade inibitória das folhas e caule de Kalanchoe brasiliensis Cambess frente a microrganismos com diferentes perfis de resistência a antibióticos
In Vitro / Polyphenols
Expression of Serotonin Transporter mRNA in Human Brainstem Raphe Nuclei
Psychopharmacology / Depression / Schizophrenia / Neuropsychopharmacology / Gene expression / In Situ Hybridization / Serotonin / In Vitro / Humans / Female / Serotonin Transporter / Male / Membrane transport proteins / Aged / Middle Aged / Adult / Normal / Dorsal raphe / In Situ Hybridization / Serotonin / In Vitro / Humans / Female / Serotonin Transporter / Male / Membrane transport proteins / Aged / Middle Aged / Adult / Normal / Dorsal raphe
Triazoloquinazolines as a novel class of phosphodiesterase 10A (PDE10A) inhibitors
Organic Chemistry / Schizophrenia / Structure / Modeling / Macromolecular X-Ray Crystallography / In Vitro / Permeability / Animals / Phosphodiesterase Inhibitors / Rats / Molecular Model / Bioorganic and medicinal Chemistry / Benzimidazoles / Protein Binding / Chemical Synthesis / Molecular Structure / Quinazolines / In Vitro / Permeability / Animals / Phosphodiesterase Inhibitors / Rats / Molecular Model / Bioorganic and medicinal Chemistry / Benzimidazoles / Protein Binding / Chemical Synthesis / Molecular Structure / Quinazolines
Triazoloquinazolines as a novel class of phosphodiesterase 10A (PDE10A) inhibitors
Organic Chemistry / Schizophrenia / Structure / Modeling / Macromolecular X-Ray Crystallography / In Vitro / Permeability / Animals / Phosphodiesterase Inhibitors / Rats / Molecular Model / Bioorganic and medicinal Chemistry / Benzimidazoles / Protein Binding / Chemical Synthesis / Molecular Structure / Quinazolines / In Vitro / Permeability / Animals / Phosphodiesterase Inhibitors / Rats / Molecular Model / Bioorganic and medicinal Chemistry / Benzimidazoles / Protein Binding / Chemical Synthesis / Molecular Structure / Quinazolines
Polyaspartylhydrazide Copolymer-Based Supramolecular Vesicular Aggregates as Delivery Devices for Anticancer Drugs
Engineering / Kinetics / Flow Cytometry / Polymers / Magnetic Resonance Spectroscopy / Cytotoxicity / Apoptosis / Biological Sciences / In Vitro / Humans / Peptides / Drug Delivery Systems / High Pressure Liquid Chromatography / CHEMICAL SCIENCES / Vesicle / Aqueous Solution / Drug Carriers / Biomacromolecules / Chemical Modification / Molecular Structure / Anticancer Drug / Cytotoxicity / Apoptosis / Biological Sciences / In Vitro / Humans / Peptides / Drug Delivery Systems / High Pressure Liquid Chromatography / CHEMICAL SCIENCES / Vesicle / Aqueous Solution / Drug Carriers / Biomacromolecules / Chemical Modification / Molecular Structure / Anticancer Drug
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