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In Vitro
In Vitro
Histamine activates phospholipase C in human airway epithelial cells via a phorbol ester-sensitive pathway
Calcium / Signal Transduction / Histamine / Cell line / In Vitro / Respiratory Epithelium / Phospholipase C / Respiratory Epithelium / Phospholipase C
Kojic acid–amino acid conjugates as tyrosinase inhibitors
Bioinformatics / Organic Chemistry / Kinetics / Modeling / Prediction / Enzyme Inhibitors / Stability / Genetic Algorithm / Enzyme Kinetics / In Vitro / Computer Simulation / Kojic Acid / Search Algorithm / Amino Acids / Molecular Model / Amino Acid Profile / Bioorganic and medicinal Chemistry / Enzyme Inhibitors / Stability / Genetic Algorithm / Enzyme Kinetics / In Vitro / Computer Simulation / Kojic Acid / Search Algorithm / Amino Acids / Molecular Model / Amino Acid Profile / Bioorganic and medicinal Chemistry
Determinação in vitro do fator de proteção solar (FPS) de moderadores solares
Radiation Biology / Dermatology / In Vitro / Cosmetic Dermatology / Clinical Sciences / Sunscreen
Weakly Antimalarial Flavonol Arabinofuranosides from Calycolpus w arszewiczianus
Natural Products / Pharmacognosy / Medicinal Plants / Cytotoxicity / Structural Analysis / Panama / Biological Sciences / Cell line / In Vitro / Toxicity / Resistance / Animals / Drug Resistance / Myrtaceae / CHEMICAL SCIENCES / Isolation / Trypanosoma Cruzi / Plasmodium falciparum / Antimalarials / Natural / Biological activity / Polyphenol / Chloroquine / Flavonols / Mono / Molecular Structure / Panama / Biological Sciences / Cell line / In Vitro / Toxicity / Resistance / Animals / Drug Resistance / Myrtaceae / CHEMICAL SCIENCES / Isolation / Trypanosoma Cruzi / Plasmodium falciparum / Antimalarials / Natural / Biological activity / Polyphenol / Chloroquine / Flavonols / Mono / Molecular Structure
Sensibilidade de Colletotrichum gloeosporioides (mancha manteigosa do cafeeiro) a diferentes concentrações de fungicidas
In Vitro / Fungicides / Colletotrichum gloeosporioides
Discovery of a series of aminopiperidines as novel iNOS inhibitors
Organic Chemistry / Enzyme Inhibitors / In Vitro / Humans / Amines / Blood Pressure / Drug Design / Active site / Nitric Oxide Synthase / Bioorganic and medicinal Chemistry / Structure activity Relationship / Isozyme / Chemical Synthesis / Selectivity / Piperidines / Blood Pressure / Drug Design / Active site / Nitric Oxide Synthase / Bioorganic and medicinal Chemistry / Structure activity Relationship / Isozyme / Chemical Synthesis / Selectivity / Piperidines
Discovery of a series of aminopiperidines as novel iNOS inhibitors
Organic Chemistry / Enzyme Inhibitors / In Vitro / Humans / Amines / Blood Pressure / Drug Design / Active site / Nitric Oxide Synthase / Bioorganic and medicinal Chemistry / Structure activity Relationship / Isozyme / Chemical Synthesis / Selectivity / Piperidines / Blood Pressure / Drug Design / Active site / Nitric Oxide Synthase / Bioorganic and medicinal Chemistry / Structure activity Relationship / Isozyme / Chemical Synthesis / Selectivity / Piperidines
IRAK-4 inhibitors. Part III: A series of imidazo[1,2-a]pyridines
Organic Chemistry / Signal Transduction / In Vitro / Kinase inhibitor / Pyridines / Tnf alpha / Bioorganic and medicinal Chemistry / Structure activity Relationship / Chemical Synthesis / Protein Kinase Inhibitors / Molecular Structure / Tnf alpha / Bioorganic and medicinal Chemistry / Structure activity Relationship / Chemical Synthesis / Protein Kinase Inhibitors / Molecular Structure
IRAK-4 inhibitors. Part III: A series of imidazo[1,2- a]pyridines
Organic Chemistry / Signal Transduction / In Vitro / Kinase inhibitor / Pyridines / Tnf alpha / Bioorganic and medicinal Chemistry / Structure activity Relationship / Chemical Synthesis / Protein Kinase Inhibitors / Molecular Structure / Tnf alpha / Bioorganic and medicinal Chemistry / Structure activity Relationship / Chemical Synthesis / Protein Kinase Inhibitors / Molecular Structure
Weakly Antimalarial Flavonol Arabinofuranosides from Calycolpus w arszewiczianus
Natural Products / Pharmacognosy / Medicinal Plants / Cytotoxicity / Structural Analysis / Panama / Biological Sciences / Cell line / In Vitro / Toxicity / Resistance / Animals / Drug Resistance / Myrtaceae / CHEMICAL SCIENCES / Isolation / Trypanosoma Cruzi / Plasmodium falciparum / Antimalarials / Natural / Biological activity / Polyphenol / Chloroquine / Flavonols / Mono / Molecular Structure / Panama / Biological Sciences / Cell line / In Vitro / Toxicity / Resistance / Animals / Drug Resistance / Myrtaceae / CHEMICAL SCIENCES / Isolation / Trypanosoma Cruzi / Plasmodium falciparum / Antimalarials / Natural / Biological activity / Polyphenol / Chloroquine / Flavonols / Mono / Molecular Structure
4-Amino-6-arylamino-pyrimidine-5-carbaldehyde hydrazones as potent ErbB-2/EGFR dual kinase inhibitors
Organic Chemistry / Modeling / Pharmacokinetics / Pharmaceutical Chemistry / Signal Transduction / Crystal structure / X Rays / In Vitro / Humans / Animals / Drug Design / Kinase inhibitor / Design Rationale / In Vivo / Hydrazones / Rats / Oximes / Molecular Model / Molecular Conformation / Bioorganic and medicinal Chemistry / Growth Factor / Structure activity Relationship / Chemical Synthesis / Protein Kinase Inhibitors / Receptor Tyrosine Kinase / Crystal structure / X Rays / In Vitro / Humans / Animals / Drug Design / Kinase inhibitor / Design Rationale / In Vivo / Hydrazones / Rats / Oximes / Molecular Model / Molecular Conformation / Bioorganic and medicinal Chemistry / Growth Factor / Structure activity Relationship / Chemical Synthesis / Protein Kinase Inhibitors / Receptor Tyrosine Kinase
In vitro post-meiotic germ cell development from human embryonic stem cells
Human Embryonic Stem Cells / Flow Cytometry / Fluorescence Microscopy / Cell Cycle / Human embryonic stem cell / Stem Cell / Embryo / Cell line / In Vitro / Cell Differentiation / Humans / Germ Cells / Testosterone / Spermatogenesis / Female / Male / Embryonic Stem Cells / Human reproduction / Embryonic Development / Time Factors / Biological markers / Niche / Germ Cell / Oocyte / Estradiol / Dihydrotestosterone / Gene expression profiling / Cell Aggregation / Stem Cell / Embryo / Cell line / In Vitro / Cell Differentiation / Humans / Germ Cells / Testosterone / Spermatogenesis / Female / Male / Embryonic Stem Cells / Human reproduction / Embryonic Development / Time Factors / Biological markers / Niche / Germ Cell / Oocyte / Estradiol / Dihydrotestosterone / Gene expression profiling / Cell Aggregation
In Vitro Potency of CXA-101, a Novel Cephalosporin, against Pseudomonas aeruginosa Displaying Various Resistance Phenotypes, Including Multidrug Resistance
Microbiology / Medical Microbiology / Adolescent / In Vitro / Humans / Child / Multidrug Resistance / Bacteria / Young Adult / Infant / Cephalosporins / Phenotype / Pseudomonas aeruginosa / Aged / Middle Aged / Anti-Bacterial Agents / Adult / Microbial Sensitivity Tests / Pseudomonas Aeruginosa / Cross-infection / Child preschool / Child / Multidrug Resistance / Bacteria / Young Adult / Infant / Cephalosporins / Phenotype / Pseudomonas aeruginosa / Aged / Middle Aged / Anti-Bacterial Agents / Adult / Microbial Sensitivity Tests / Pseudomonas Aeruginosa / Cross-infection / Child preschool
Light-activated gene transduction enhances adeno-associated virus vector-mediated gene expression in human articular chondrocytes
Pathology / Immunology / Immunohistochemistry / Adolescent / Gene expression / Cell Culture / In Vitro / Humans / Virus / Female / Male / Gene / Arthritis / Transduction / VECTOR / Clinical Sciences / Middle Aged / Gen / Adult / Public health systems and services research / Articular Cartilage Wear / Chondrocytes / Cell Culture / In Vitro / Humans / Virus / Female / Male / Gene / Arthritis / Transduction / VECTOR / Clinical Sciences / Middle Aged / Gen / Adult / Public health systems and services research / Articular Cartilage Wear / Chondrocytes
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