Lysosomes

Neu4, a Novel Human Lysosomal Lumen Sialidase, Confers Normal Phenotype to Sialidosis and Galactosialidosis Cells

Electron Microscopy / Molecular Biology / Catalysis / Mass Spectrometry / Biological Chemistry / Confocal Microscopy / Biological Sciences / Humans / Mutation / Animals / Biological / Skin / Plasmids / Phenotype / Neuraminidase / CHEMICAL SCIENCES / Substrate Specificity / Transfection / Amino Acid Sequence / Subcellular Fractions / Lysosomes / Hydrogen-Ion Concentration / Cytoplasm / Molecular Sequence Data / Cell Membrane / Confocal Microscopy / Biological Sciences / Humans / Mutation / Animals / Biological / Skin / Plasmids / Phenotype / Neuraminidase / CHEMICAL SCIENCES / Substrate Specificity / Transfection / Amino Acid Sequence / Subcellular Fractions / Lysosomes / Hydrogen-Ion Concentration / Cytoplasm / Molecular Sequence Data / Cell Membrane

Ultrastructure of a fibroxanthosarcoma (malignant fibroxanthoma)

Electron Microscopy / Cancer / Mitochondria / Lipids / Humans / Female / Endoplasmic Reticulum / Fibrosarcoma / Cell nucleus / Adult / Lysosomes / Golgi Apparatus / Cytoplasm / Scalp / Skin Neoplasms / Female / Endoplasmic Reticulum / Fibrosarcoma / Cell nucleus / Adult / Lysosomes / Golgi Apparatus / Cytoplasm / Scalp / Skin Neoplasms

Lysosomal Network Proteins as Potential Novel CSF Biomarkers for Alzheimer’s Disease

Autophagy / Humans / Female / Male / Clinical Sciences / Aged / Middle Aged / Adult / Biological markers / Lysosomes / Alzheimer Disease / Neurosciences / Endosomes / Aged / Middle Aged / Adult / Biological markers / Lysosomes / Alzheimer Disease / Neurosciences / Endosomes

Cardiac autophagy is a maladaptive response to hemodynamic stress

Transmission Electron Microscopy / Autophagy / Cell line / Mice / Animal Feed / Animals / Clinical / Male / Proteins / Rats / Myocardium / Biological markers / Lysosomes / Aorta / Clinical Investigation / Heart Diseases / Animals / Clinical / Male / Proteins / Rats / Myocardium / Biological markers / Lysosomes / Aorta / Clinical Investigation / Heart Diseases

Neu4, a Novel Human Lysosomal Lumen Sialidase, Confers Normal Phenotype to Sialidosis and Galactosialidosis Cells

Electron Microscopy / Molecular Biology / Catalysis / Mass Spectrometry / Biological Chemistry / Confocal Microscopy / Biological Sciences / Humans / Mutation / Animals / Biological / Skin / Plasmids / Phenotype / Neuraminidase / CHEMICAL SCIENCES / Substrate Specificity / Transfection / Amino Acid Sequence / Human Fibroblasts / Subcellular Fractions / Lysosomes / Hydrogen-Ion Concentration / Cytoplasm / Molecular Sequence Data / Cell Membrane / Confocal Microscopy / Biological Sciences / Humans / Mutation / Animals / Biological / Skin / Plasmids / Phenotype / Neuraminidase / CHEMICAL SCIENCES / Substrate Specificity / Transfection / Amino Acid Sequence / Human Fibroblasts / Subcellular Fractions / Lysosomes / Hydrogen-Ion Concentration / Cytoplasm / Molecular Sequence Data / Cell Membrane

Gentamicin causes endocytosis of Na/Pi cotransporter protein (NaPi-2)

Nephrology / Urology / Dialysis / Molecular Mechanics / Kidney / Endocytosis / Animals / Male / Clinical Sciences / Anti-Bacterial Agents / Rats / Western blot / Body Weight / Side Effect / Lysosomes / Endosomes / Endocytosis / Animals / Male / Clinical Sciences / Anti-Bacterial Agents / Rats / Western blot / Body Weight / Side Effect / Lysosomes / Endosomes

Lysosomal exoglycosidases in nasal polyps

Extracellular Matrix / Humans / Female / Male / Young Adult / Aged / Middle Aged / Adult / Lysosomes / Nasal Mucosa / Aged / Middle Aged / Adult / Lysosomes / Nasal Mucosa

Molecular pathogenesis of a disease: structural consequences of aspartylglucosaminuria mutations

Confocal Microscopy / Biological Sciences / DNA / Humans / Mutation / Human Molecular Genetics / Endoplasmic Reticulum / Fluorescent Antibody Technique / Active site / Amino Acid Profile / Transfection / Protein Conformation / Amino Acid Sequence / Body of Knowledge / Human Fibroblasts / Lysosomes / Ligands / Lysosomal Storage Diseases / Human Molecular Genetics / Endoplasmic Reticulum / Fluorescent Antibody Technique / Active site / Amino Acid Profile / Transfection / Protein Conformation / Amino Acid Sequence / Body of Knowledge / Human Fibroblasts / Lysosomes / Ligands / Lysosomal Storage Diseases

A novel aspartylglucosaminuria mutation affects translocation of aspartylglucosaminidase

Genetics / Human / Finland / Cercopithecus aethiops / Cell line / Humans / Animals / Male / Endoplasmic Reticulum / Clinical Sciences / Transfection / Amino Acid Sequence / Amino Acid Substitution Rates / Structure activity Relationship / Lysosomes / Protein Transport / Lysosomal Storage Diseases / Humans / Animals / Male / Endoplasmic Reticulum / Clinical Sciences / Transfection / Amino Acid Sequence / Amino Acid Substitution Rates / Structure activity Relationship / Lysosomes / Protein Transport / Lysosomal Storage Diseases

Transport of human lysosomal neuraminidase to mature lysosomes requires protective protein/cathepsin A

Biological Sciences / Humans / Animals / Cell Fractionation / Phosphorylation / Neuraminidase / Transfection / Molecular weight / Carboxypeptidases / Lysosomes / Neuraminidase / Transfection / Molecular weight / Carboxypeptidases / Lysosomes

Secreted aspartic proteases of Candida albicans, Candida tropicalis, Candida parapsilosis and Candida lusitaniae

Immunology / Signal Transduction / Humans / Candida albicans / Potassium / European / Monocytes / Inflammasomes / Lysosomes / Superoxides / Biochemistry and cell biology / Interleukin / European / Monocytes / Inflammasomes / Lysosomes / Superoxides / Biochemistry and cell biology / Interleukin

Specific ultrastructural markers of human pinealomas

Electron Microscopy / Adolescent / Biopsy / Humans / Female / Male / Astrocyte / Microtubules / Clinical Sciences / Inclusion Bodies / Aged / Adult / Lysosomes / Neurosciences / Brain Neoplasms / Male / Astrocyte / Microtubules / Clinical Sciences / Inclusion Bodies / Aged / Adult / Lysosomes / Neurosciences / Brain Neoplasms

Morphological features of osteoclasts derived from a co-culture system

Scanning Electron Microscopy / Transmission Electron Microscopy / Macrophages / Extracellular Matrix / Cell line / Mice / Animals / Osteoclasts / Clinical Sciences / Dentin / Cell communication / Osteoblasts / Lysosomes / Bone Resorption / Biochemistry and cell biology / Mice / Animals / Osteoclasts / Clinical Sciences / Dentin / Cell communication / Osteoblasts / Lysosomes / Bone Resorption / Biochemistry and cell biology

Senescence-associated β-galactosidase is lysosomal β-galactosidase

Aging / Gene expression / Biological Sciences / RNA interference / Humans / Mutation / HeLa cells / Human Fibroblasts / Lysosomes / Mutation / HeLa cells / Human Fibroblasts / Lysosomes

Autophagy Is a Protective Mechanism for Human Melanoma Cells under Acidic Stress

Autophagy / Biological Chemistry / Biological Sciences / Humans / Melanoma / Phosphorylation / CHEMICAL SCIENCES / Physiological Stress Markers / Lysosomes / Hydrogen-Ion Concentration / Phosphorylation / CHEMICAL SCIENCES / Physiological Stress Markers / Lysosomes / Hydrogen-Ion Concentration

TMEM106B p.T185S regulates TMEM106B protein levels: implications for frontotemporal dementia

Neurochemistry / Membrane Proteins / Immunohistochemistry / Western blotting / Humans / Mutagenesis / Mutation / Female / Male / Glycosylation / Aged / Fluorescent Antibody Technique / Genotype / HeLa cells / Frontotemporal Dementia / Lysosomes / Neurosciences / Enzyme Linked Immunosorbent Assay / Cohort Studies / Isomerism / Mutagenesis / Mutation / Female / Male / Glycosylation / Aged / Fluorescent Antibody Technique / Genotype / HeLa cells / Frontotemporal Dementia / Lysosomes / Neurosciences / Enzyme Linked Immunosorbent Assay / Cohort Studies / Isomerism

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