Macromolecular X-Ray Crystallography - Page 7

Tetrameric c-di-GMP Mediates Effective Transcription Factor Dimerization to Control Streptomyces Development

Transcription Factors / Macromolecular X-Ray Crystallography / Biological Sciences / Streptomyces / Sequence alignment / Cell / Amino Acid Sequence / cyclic GMP / Dimerization / Cell / Amino Acid Sequence / cyclic GMP / Dimerization

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Structural Basis for NADH/NAD+ Redox Sensing by a Rex Family Repressor

Gene regulation / Gene expression / Macromolecular X-Ray Crystallography / Molecular Mechanics / Cell and Molecular Biology / Biological Sciences / Surface plasmon resonance / Gram Positive Bacteria / DNA binding / Protein Conformation / NAD / Site-directed Mutagenesis / Oxidation-Reduction / Biological Sciences / Surface plasmon resonance / Gram Positive Bacteria / DNA binding / Protein Conformation / NAD / Site-directed Mutagenesis / Oxidation-Reduction

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Crystal Structure of Glycyl Endopeptidase from Carica papaya: A Cysteine Endopeptidase of Unusual Substrate Specificity

Biochemistry / Macromolecular X-Ray Crystallography / Crystal structure / Sequence alignment / Plants / Carica papaya / Substrate Specificity / Cysteine endopeptidases / Amino Acid Sequence / Structure activity Relationship / Biochemistry and cell biology / cystatin B / Cysteine Proteinase Inhibitors / Carica papaya / Substrate Specificity / Cysteine endopeptidases / Amino Acid Sequence / Structure activity Relationship / Biochemistry and cell biology / cystatin B / Cysteine Proteinase Inhibitors

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Structural basis for iron piracy by pathogenic Neisseria

Biochemistry / Microbiology / Electron Microscopy / Structural Biology / Molecular Dynamics Simulation / Small angle X-ray and neutron scattering / Small Angle X Ray Scattering / Intelligent Transport System / Multidisciplinary / Nature / Macromolecular X-Ray Crystallography / Crystal structure / Humans / Mice / Animals / Medical Research / Transferrin / Neisseria / Iron / Cattle / X ray diffraction / Protein Conformation / Species Specificity / Structure activity Relationship / Cell Surface Markers / Bacterial meningitis / Outer Membrane Protein / Apoproteins / Small angle X-ray and neutron scattering / Small Angle X Ray Scattering / Intelligent Transport System / Multidisciplinary / Nature / Macromolecular X-Ray Crystallography / Crystal structure / Humans / Mice / Animals / Medical Research / Transferrin / Neisseria / Iron / Cattle / X ray diffraction / Protein Conformation / Species Specificity / Structure activity Relationship / Cell Surface Markers / Bacterial meningitis / Outer Membrane Protein / Apoproteins

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Structural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1

Kinetics / Macromolecular X-Ray Crystallography / Biological Sciences / Crystal structure / Humans / Endoplasmic Reticulum / Antigen Presentation / Special functions / CHEMICAL SCIENCES / Active site / Substrate Specificity / Structure activity Relationship / Conformational Change / Antigens / MHC class I / Endoplasmic Reticulum / Antigen Presentation / Special functions / CHEMICAL SCIENCES / Active site / Substrate Specificity / Structure activity Relationship / Conformational Change / Antigens / MHC class I

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The TB Structural Genomics Consortium: A decade of progress

Genomics / Drug Discovery / International Cooperation / Structural Genomics / Macromolecular X-Ray Crystallography / Tuberculosis / Humans / Mycobacterium tuberculosis / SAXS / TB / Nmr / Magnetic Resonance / Drug Design / PPI / Protein structure / Protein Interaction / NAD / X Ray Crystallography / PDB / Tuberculosis / Humans / Mycobacterium tuberculosis / SAXS / TB / Nmr / Magnetic Resonance / Drug Design / PPI / Protein structure / Protein Interaction / NAD / X Ray Crystallography / PDB

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Naturally Processed Non-canonical HLA-A*02:01 Presented Peptides

Mass Spectrometry / Flow Cytometry / Biological Chemistry / Macromolecular X-Ray Crystallography / Biological Sciences / Cell line / Humans / Peptides / CHEMICAL SCIENCES / Protein Conformation / Cell line / Humans / Peptides / CHEMICAL SCIENCES / Protein Conformation

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Si-enterobactin from the endophytic Streptomyces sp. KT-S1-B5 – a potential silicon transporter in Nature?

Silicon / Macromolecular X-Ray Crystallography / Streptomyces / Plant Roots / CHEMICAL SCIENCES / Molecular Conformation / Piper / Ligands / Molecular Conformation / Piper / Ligands

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Structural and Functional Evidence for Bacillus subtilis PaiA as a Novel N1-Spermidine/Spermine Acetyltransferase

Catalysis / Kinetics / Biological Chemistry / Macromolecular X-Ray Crystallography / Polyamines / Biological Sciences / Escherichia coli / Biological / CHEMICAL SCIENCES / Oxygen / Bacillus subtilis / Protein Conformation / Amino Acid Sequence / Structure activity Relationship / Protein Binding / Cations / Dimerization / Molecular Sequence Data / Biological Sciences / Escherichia coli / Biological / CHEMICAL SCIENCES / Oxygen / Bacillus subtilis / Protein Conformation / Amino Acid Sequence / Structure activity Relationship / Protein Binding / Cations / Dimerization / Molecular Sequence Data

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Cocrystal Structures of Diaminopimelate Decarboxylase

Structure / Kinetics / Structural Genomics / Macromolecular X-Ray Crystallography / Antibiotic Resistance / Biological Sciences / Drug Resistance / Staphylococcus aureus / Enzyme / CHEMICAL SCIENCES / Spectrum / Anti-Bacterial Agents / Protein Secondary Structure Prediction / Substrate Specificity / Protein Conformation / Amino Acid Sequence / Protein Binding / X Ray Crystallography / Kinetic Parameter / Dimerization / Molecular Sequence Data / Biological Sciences / Drug Resistance / Staphylococcus aureus / Enzyme / CHEMICAL SCIENCES / Spectrum / Anti-Bacterial Agents / Protein Secondary Structure Prediction / Substrate Specificity / Protein Conformation / Amino Acid Sequence / Protein Binding / X Ray Crystallography / Kinetic Parameter / Dimerization / Molecular Sequence Data

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Crystal structure of NMA1982 from Neisseria meningitidis at 1.5 Å resolution provides a structural scaffold for nonclassical, eukaryotic-like phosphatases

Protein Science / Macromolecular X-Ray Crystallography / Biological Sciences / Crystal structure / Mathematical Sciences / Proteins / Protein Secondary Structure Prediction / Amino Acid Sequence / Molecular Sequence Data / Proteins / Protein Secondary Structure Prediction / Amino Acid Sequence / Molecular Sequence Data

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Assessment of Pseudomonas aeruginosa N5,N10-Methylenetetrahydrofolate Dehydrogenase - Cyclohydrolase as a Potential Antibacterial Drug Target

Engineering / Physics / Chemistry / Biology / Medicine / Multidisciplinary / Macromolecular X-Ray Crystallography / Biocatalysis / Humans / PLoS one / Pseudomonas aeruginosa / Anti-Bacterial Agents / Protein Secondary Structure Prediction / Reproducibility of Results / Microbial Sensitivity Tests / Pseudomonas Aeruginosa / Biological Assay / Ligands / Multidisciplinary / Macromolecular X-Ray Crystallography / Biocatalysis / Humans / PLoS one / Pseudomonas aeruginosa / Anti-Bacterial Agents / Protein Secondary Structure Prediction / Reproducibility of Results / Microbial Sensitivity Tests / Pseudomonas Aeruginosa / Biological Assay / Ligands

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Cyclotides, a Novel Ultrastable Polypeptide Scaffold for Drug Discovery

Drug Discovery / Macromolecular X-Ray Crystallography / Protein Stability / Genetic Engineering / Humans / Animals / Cyclotides / Protein Conformation / Amino Acid Sequence / Drug Stability / Antineoplastic Agents / Animals / Cyclotides / Protein Conformation / Amino Acid Sequence / Drug Stability / Antineoplastic Agents

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L-cysteinium semioxalate: a new monoclinic polymorph or a hydrate?

Inorganic Chemistry / Water / Crystallization / Macromolecular X-Ray Crystallography / Hydrogen Bonding / Cysteine / Molecular Conformation / Ions / Molecular Structure / Cysteine / Molecular Conformation / Ions / Molecular Structure

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N 1 -Benzoyl- N 2 -[1-(1-naphthyl)ethyl]- trans -1,2-diaminocyclohexanes: Development of 4-Chlorophenylcarboxamide (Calhex 231) as a New Calcium Sensing Receptor Ligand Demonstrating Potent Calcilytic Activity

Organic Chemistry / Medicinal Chemistry / Macromolecular X-Ray Crystallography / Animals / Calcium Sensing Receptor / Rats / Medicinal / Protein Conformation / Structure activity Relationship / Ligands / Benzamides / Molecular Structure / Rats / Medicinal / Protein Conformation / Structure activity Relationship / Ligands / Benzamides / Molecular Structure

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Venusol from Gunnera perpensa: structural and activity studies

Natural Products Chemistry / Phytochemistry / Medicinal Plants / Macromolecular X-Ray Crystallography / Biological Sciences / Smooth muscle / Female / Animals / CHEMICAL SCIENCES / Rats / X ray diffraction / Muscle contraction / Rhizome / Uterus / Lactic Acid / Succinic Acid / Aqueous Extract / Glycosides / Molecular Structure / Ileum / Ellagic acid / Smooth muscle / Female / Animals / CHEMICAL SCIENCES / Rats / X ray diffraction / Muscle contraction / Rhizome / Uterus / Lactic Acid / Succinic Acid / Aqueous Extract / Glycosides / Molecular Structure / Ileum / Ellagic acid

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