Medicinal

Kynurenamines as Neural Nitric Oxide Synthase Inhibitors

Organic Chemistry / Medicinal Chemistry / Enzyme Inhibitors / Animals / Rats / Medicinal / Molecular Conformation / Medicinal / Molecular Conformation

Cyclopropamitosenes

Organic Chemistry / Medicinal Chemistry / Electrochemistry / Cell Division / Animals / Quinones / Enzyme / Tetrahedron / Medicinal / Mechanism of action / Biological activity / Anti Cancer Drugs / Oxidation-Reduction / Anti Cancer / Quinones / Enzyme / Tetrahedron / Medicinal / Mechanism of action / Biological activity / Anti Cancer Drugs / Oxidation-Reduction / Anti Cancer

Phosphoramidate Dinucleosides as Hepatitis C Virus Polymerase Inhibitors

Organic Chemistry / Medicinal Chemistry / Enzyme Inhibitors / Magnetic Resonance Spectroscopy / Humans / Hepatitis C Virus / Organophosphorus Compounds / Medicinal / Nucleosides / Oxidation-Reduction / Hepatitis C Virus / Organophosphorus Compounds / Medicinal / Nucleosides / Oxidation-Reduction

A Novel Potent Nicotinamide Phosphoribosyltransferase Inhibitor Synthesized via Click Chemistry

Organic Chemistry / Medicinal Chemistry / Enzyme Inhibitors / Autophagy / Humans / Animals / Medicinal / Structure activity Relationship / Protein Binding / Antineoplastic Agents / Alkynes / Animals / Medicinal / Structure activity Relationship / Protein Binding / Antineoplastic Agents / Alkynes

Novel Antibacterial Class: A Series of Tetracyclic Derivatives

Organic Chemistry / Medicinal Chemistry / Streptococcus pneumoniae / Humans / Anti-Bacterial Agents / Medicinal / Microbial Sensitivity Tests / B Lymphocytes / Structure activity Relationship / Protein Biosynthesis / Medicinal / Microbial Sensitivity Tests / B Lymphocytes / Structure activity Relationship / Protein Biosynthesis

Phosphoramidate Dinucleosides as Hepatitis C Virus Polymerase Inhibitors

Organic Chemistry / Medicinal Chemistry / Modeling / Enzyme Inhibitors / Magnetic Resonance Spectroscopy / In Vitro / Humans / Virus / Hepatitis C Virus / Organophosphorus Compounds / Medicinal / Molecular Model / Nucleosides / Chemical Synthesis / Oxidation-Reduction / In Vitro / Humans / Virus / Hepatitis C Virus / Organophosphorus Compounds / Medicinal / Molecular Model / Nucleosides / Chemical Synthesis / Oxidation-Reduction

Phosphoramidate Dinucleosides as Hepatitis C Virus Polymerase Inhibitors

Organic Chemistry / Medicinal Chemistry / Modeling / Enzyme Inhibitors / Magnetic Resonance Spectroscopy / In Vitro / Humans / Virus / Hepatitis C Virus / Organophosphorus Compounds / Medicinal / Molecular Model / Nucleosides / Chemical Synthesis / Oxidation-Reduction / In Vitro / Humans / Virus / Hepatitis C Virus / Organophosphorus Compounds / Medicinal / Molecular Model / Nucleosides / Chemical Synthesis / Oxidation-Reduction

A Prodomain Peptide of Plasmodium falciparum Cysteine Protease (Falcipain-2) Inhibits Malaria Parasite Development

Organic Chemistry / Medicinal Chemistry / Animals / Peptides / Medicinal / Plasmodium falciparum / Antimalarials / Cysteine endopeptidases / Structure activity Relationship / Erythrocytes / Hydrolysis / Hemoglobins / Plasmodium falciparum / Antimalarials / Cysteine endopeptidases / Structure activity Relationship / Erythrocytes / Hydrolysis / Hemoglobins

A prodomain peptide of plasmodium falciparum cysteine protease (falcipain-2) inhibits malaria parasite development

Organic Chemistry / Medicinal Chemistry / Animals / Peptides / Medicinal / Plasmodium falciparum / Antimalarials / Cysteine endopeptidases / Structure activity Relationship / Erythrocytes / Hydrolysis / Hemoglobins / Plasmodium falciparum / Antimalarials / Cysteine endopeptidases / Structure activity Relationship / Erythrocytes / Hydrolysis / Hemoglobins

N 1 -Benzoyl- N 2 -[1-(1-naphthyl)ethyl]- trans -1,2-diaminocyclohexanes: Development of 4-Chlorophenylcarboxamide (Calhex 231) as a New Calcium Sensing Receptor Ligand Demonstrating Potent Calcilytic Activity

Organic Chemistry / Medicinal Chemistry / Macromolecular X-Ray Crystallography / Animals / Calcium Sensing Receptor / Rats / Medicinal / Protein Conformation / Structure activity Relationship / Ligands / Benzamides / Molecular Structure / Rats / Medicinal / Protein Conformation / Structure activity Relationship / Ligands / Benzamides / Molecular Structure

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