Mode of action

Macrophage Responses to Silica Nanoparticles are Highly Conserved Across Particle Sizes

Particle Physics / Gene regulation / Electrochemistry / Nanoparticles / Macrophages / Gene expression / Cell line / Mice / Protein Secretion / Silica / Animals / Light / Suspensions / Mode of action / Microarray Analysis / Surface Area / Particle Size / Biological Process / Gene Set Enrichment Analysis / Biological activity / Health Effect / Silicon Dioxide / Physical Properties / Enzyme Linked Immunosorbent Assay / Gene expression profiling / Gene expression / Cell line / Mice / Protein Secretion / Silica / Animals / Light / Suspensions / Mode of action / Microarray Analysis / Surface Area / Particle Size / Biological Process / Gene Set Enrichment Analysis / Biological activity / Health Effect / Silicon Dioxide / Physical Properties / Enzyme Linked Immunosorbent Assay / Gene expression profiling

Penicillium daleae, a soil fungus able to degrade rhamnogalacturonan II, a complex pectic polysaccharide

Environmental Biotechnology / Fruit and vegetables / Enzyme / Mode of action / Gas Chromatography/mass Spectrometry / Plant Cell Wall / Microbial enzyme Technology / Cell Wall / Forest Soil Ecology / Carbon Source / Plant Cell Wall / Microbial enzyme Technology / Cell Wall / Forest Soil Ecology / Carbon Source

Dehydrozaluzanin C, a natural sesquiterpenolide, causes rapid plasma membrane leakage

Phytochemistry / Cucumber / Biological Sciences / Glutathione / Plant growth / CHEMICAL SCIENCES / Mode of action / Membrane Integrity / Amino Acid Profile / Plasma Membrane / CHEMICAL SCIENCES / Mode of action / Membrane Integrity / Amino Acid Profile / Plasma Membrane

Bioactive natural peptides

NMR Spectroscopy /  Enzymatic hydrolysis / Antimicrobial Peptide / Single Cell / Mode of action / Amino Acid Profile / Large Scale / Biological activity / Amino Acid Sequence / Antitumor Activity / Lipid Bilayer / Amino Acid Profile / Large Scale / Biological activity / Amino Acid Sequence / Antitumor Activity / Lipid Bilayer

Eosin B as a Novel Antimalarial Agent for Drug-Resistant Plasmodium falciparum

Microbiology / Medical Microbiology / Cell Culture / Toxoplasma gondii / Cell line / Humans / Animals / Drug Resistance / Life Cycle / Enzyme / Mode of action / Research Needs / Active site / Thioredoxin / Plasmodium falciparum / Antimalarials / Antimicrobial agents / Multienzyme complexes / Human Fibroblasts / Glutathione Reductase / Thioredoxin reductase / Dihydrofolate Reductase / Humans / Animals / Drug Resistance / Life Cycle / Enzyme / Mode of action / Research Needs / Active site / Thioredoxin / Plasmodium falciparum / Antimalarials / Antimicrobial agents / Multienzyme complexes / Human Fibroblasts / Glutathione Reductase / Thioredoxin reductase / Dihydrofolate Reductase

Bioactive natural peptides

NMR Spectroscopy /  Enzymatic hydrolysis / Antimicrobial Peptide / Single Cell / Mode of action / Amino Acid Profile / Large Scale / Biological activity / Amino Acid Sequence / Antitumor Activity / Lipid Bilayer / Amino Acid Profile / Large Scale / Biological activity / Amino Acid Sequence / Antitumor Activity / Lipid Bilayer

Assessment of the anthelmintic effect of natural plant cysteine proteinases against the gastrointestinal nematode, Heligmosomoides polygyrus, in vitro

Parasitology / Scanning Electron Microscopy / Humans / Mice / Female / Animals / Male / Ficus / Mode of action / Plant extracts / Ananas / Nematoda / Cysteine endopeptidases / Veterinary Sciences / Mechanism of action / Anthelmintics / PLANT PROTEINS / Cysteine Proteinase Inhibitors / Animals / Male / Ficus / Mode of action / Plant extracts / Ananas / Nematoda / Cysteine endopeptidases / Veterinary Sciences / Mechanism of action / Anthelmintics / PLANT PROTEINS / Cysteine Proteinase Inhibitors

Eosin B as a Novel Antimalarial Agent for Drug-Resistant Plasmodium falciparum

Microbiology / Medical Microbiology / Cell Culture / Toxoplasma gondii / Cell line / Humans / Animals / Drug Resistance / Life Cycle / Enzyme / Mode of action / Research Needs / Active site / Thioredoxin / Plasmodium falciparum / Antimalarials / Antimicrobial agents / Multienzyme complexes / Human Fibroblasts / Glutathione Reductase / Thioredoxin reductase / Dihydrofolate Reductase / Humans / Animals / Drug Resistance / Life Cycle / Enzyme / Mode of action / Research Needs / Active site / Thioredoxin / Plasmodium falciparum / Antimalarials / Antimicrobial agents / Multienzyme complexes / Human Fibroblasts / Glutathione Reductase / Thioredoxin reductase / Dihydrofolate Reductase

A framework for fit-for-purpose dose response assessment

Risk assessment / Humans / Animals / RFD / Framework / Moa / Mode of action / Endogenous / Nrc / Risk Assessment / CPF / Moa / Mode of action / Endogenous / Nrc / Risk Assessment / CPF

A microbiological assessment of novel nitrofuranylamides as anti-tuberculosis agents

Microbiology / Medical Microbiology / Evaluation / Tuberculosis / Humans / Mycobacterium tuberculosis / Antimicrobial activity / Antimicrobial chemotherapy / Polycyclic aromatic hydrocarbons (PAHs) / Mode of action / Microbial Sensitivity Tests / Latency / Microbial Viability / Mycobacterium bovis / Molecular Structure / Mycobacterium tuberculosis / Antimicrobial activity / Antimicrobial chemotherapy / Polycyclic aromatic hydrocarbons (PAHs) / Mode of action / Microbial Sensitivity Tests / Latency / Microbial Viability / Mycobacterium bovis / Molecular Structure

ReviewDiatomaceous earths, a group of natural insecticides

Zoology / Silica / Insects / FORMULATION / Mode of action / Fresh water / Physical Properties / Diatomaceous Earth / Fresh water / Physical Properties / Diatomaceous Earth

A framework for fit-for-purpose dose response assessment

Risk assessment / Humans / Animals / RFD / Framework / Moa / Mode of action / Endogenous / Nrc / Risk Assessment / CPF / Moa / Mode of action / Endogenous / Nrc / Risk Assessment / CPF

Structural requirement of arylindolylpropenones as anti-bladder carcinoma cells agents

Organic Chemistry / Flow Cytometry / Cell Cycle / Cell line / Bladder Cancer / Humans / Chalcones / Mode of action / Bioorganic and medicinal Chemistry / Structure activity Relationship / Antineoplastic Agents / Humans / Chalcones / Mode of action / Bioorganic and medicinal Chemistry / Structure activity Relationship / Antineoplastic Agents
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