Molecular Structure

Cyanopyridyl containing 1,4-dihydroindeno[1,2-c]pyrazoles as potent checkpoint kinase 1 inhibitors: Improving oral biovailability

Organic Chemistry / Hydrogen / Pharmacokinetics / DNA damage / Signal Transduction / In Vitro / Protein Kinases / Mice / Animals / Bioavailability / In Vivo / Rats / Pyridines / Bioorganic and medicinal Chemistry / Pyrazoles / Cyanides / Structure activity Relationship / Chemical Synthesis / Protein Kinase Inhibitors / Molecular Structure / In Vitro / Protein Kinases / Mice / Animals / Bioavailability / In Vivo / Rats / Pyridines / Bioorganic and medicinal Chemistry / Pyrazoles / Cyanides / Structure activity Relationship / Chemical Synthesis / Protein Kinase Inhibitors / Molecular Structure

Modelling of UV-molecular spectra of several bis-pyrazolopyridines derivatives

Analytical Chemistry / Pyridines / Pyrazoles / Molecular Structure

Synthesis of potassium (2R)-2-O-α-d-glucopyranosyl-(1→6)-α-d-glucopyranosyl-2,3-dihydroxypropanoate a natural compatible solute

Organic Chemistry / Glycosylation / Carbohydrate / Biochemistry and cell biology / Molecular Structure

Novel cell-penetrating α-keto-amide calpain inhibitors as potential treatment for muscular dystrophy

Organic Chemistry / Mice / Muscular Dystrophy / Animals / Animal Model / Duchenne Muscular Dystrophy / Calpain / Amides / Molecular Structure / Cysteine Proteinase Inhibitors / Duchenne Muscular Dystrophy / Calpain / Amides / Molecular Structure / Cysteine Proteinase Inhibitors

Crystal structures of Aedes aegypti kynurenine aminotransferase

Macromolecular X-Ray Crystallography / Crystal structure / Humans / Animals / Recombinant Proteins / Aedes / Biochemistry and cell biology / Molecular Structure / Transaminases / Aedes / Biochemistry and cell biology / Molecular Structure / Transaminases

Acylated pregnane glycosides from Caralluma russeliana

Phytochemistry / Biological Sciences / CHEMICAL SCIENCES / Isolation / Plant extracts / Asclepiadaceae / Acylation / Glycosides / Molecular Structure / Asclepiadaceae / Acylation / Glycosides / Molecular Structure

Self-Assembling Cannabinomimetics:  Supramolecular Structures of N -Alkyl Amides

Natural Products / Modeling / Self Assembly / Pharmacognosy / Medicinal Plants / Biological Sciences / Micelle / In Vitro / Humans / Endocannabinoid System / CHEMICAL SCIENCES / Amides / Natural / Endocannabinoids / Monte Carlo Method / Echinacea / Molecular Structure / Biological Sciences / Micelle / In Vitro / Humans / Endocannabinoid System / CHEMICAL SCIENCES / Amides / Natural / Endocannabinoids / Monte Carlo Method / Echinacea / Molecular Structure

A chiral tetrahydro-γ-pyranonecarboxylate ester for asymmetric Nazarov cyclization

Inorganic Chemistry / Crystal structure / XRD / Molecular Structure

Structure of the sialic acid-containing O-specific polysaccharide from Salmonella enterica serovar Toucra O48 lipopolysaccharide

Polysaccharides / Magnetic Resonance Spectroscopy / Lipopolysaccharide / Methylation / European / Lipopolysaccharides / Gas Chromatography/mass Spectrometry / Sialic Acid / Hydrolysis / Biochemistry and cell biology / Molecular Structure / Lipopolysaccharides / Gas Chromatography/mass Spectrometry / Sialic Acid / Hydrolysis / Biochemistry and cell biology / Molecular Structure

Thalidomide Analogues as Anticancer Drugs

Humans / Animals / Neoplasms / Antineoplastic Agents / Thalidomide / Biochemistry and cell biology / Molecular Structure / Biochemistry and cell biology / Molecular Structure

Rutoxyl [rutin/4-acetamide-1-hydroxy-2,2,6,6-tetramethylpiperidinium] is a new member of the class of semi-natural products of high pharmacological potency

Antioxidants / Animals / Natural Product / Male / Drug Design / Rats / Wistar Rats / Biochemistry and molecular biology / Structure activity Relationship / Antineoplastic Agents / Biochemistry and cell biology / Molecular Structure / Piperidines / Rats / Wistar Rats / Biochemistry and molecular biology / Structure activity Relationship / Antineoplastic Agents / Biochemistry and cell biology / Molecular Structure / Piperidines

Novel benzimidazole derivatives as expected anticancer agents

Humans / Animals / Pheochromocytoma / Rats / Benzimidazoles / Structure activity Relationship / Cell Survival / Antineoplastic Agents / Molecular Structure / Structure activity Relationship / Cell Survival / Antineoplastic Agents / Molecular Structure

Cespihypotins Q−V, Verticillene Diterpenoids from Cespitularia hypotentaculata

Natural Products / Biological Sciences / Humans / Anthozoa / Animals / CHEMICAL SCIENCES / Diterpenes / Natural / Antineoplastic Agents / Molecular Structure / CHEMICAL SCIENCES / Diterpenes / Natural / Antineoplastic Agents / Molecular Structure

Naphthoquinoidal [1,2,3]-triazole, a new structural moiety active against Trypanosoma cruzi

Organic Chemistry / Treatment / Drug development / Macromolecular X-Ray Crystallography / In Vitro / Animals / Naphthoquinones / Chagas disease / European / Hydrogen Bonding / Trypanosoma Cruzi / Trypanocidal Agents / Triazoles / Structure activity Relationship / Cations / Chemical Synthesis / Molecular Structure / Animals / Naphthoquinones / Chagas disease / European / Hydrogen Bonding / Trypanosoma Cruzi / Trypanocidal Agents / Triazoles / Structure activity Relationship / Cations / Chemical Synthesis / Molecular Structure

Echinocystic acid 3,16-O-bisglycosides from Albizia procera

Phytochemistry / Egypt / Biological Sciences / Humans / CHEMICAL SCIENCES / Structure activity Relationship / Glycosides / Oleanolic acid / Molecular Structure / Triterpenes / Structure activity Relationship / Glycosides / Oleanolic acid / Molecular Structure / Triterpenes

Chemical Adaptor Systems

Chemistry / Drug Design / Drug Delivery Systems / CHEMICAL SCIENCES / Neoplasms / Cyclization / Antineoplastic Agents / Molecular Structure / Cyclization / Antineoplastic Agents / Molecular Structure
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