Nitriles

Diprolyl nitriles as potent dipeptidyl peptidase IV inhibitors

Organic Chemistry / Nitriles / Protease Inhibitors / Cyclization / Bioorganic and medicinal Chemistry / Type 2 Diabetes Mellitus / Structure activity Relationship / Molecular Structure / Type 2 Diabetes Mellitus / Structure activity Relationship / Molecular Structure

Flagellin of Pseudomonas aeruginosa inhibits Na+ transport in airway epithelia

Physiology / Cystic Fibrosis / Biology / Membrane Proteins / Cell Biology / Patch-clamp and imaging techniques / Response Inhibition / Humans / Nitriles / Mice / Animals / Flagella / Calcium Signaling / Medical Physiology / Mitogen Activated Protein Kinase / Pseudomonas aeruginosa / Gram-negative bacteria / Epithelial cells / Sodium / Trachea / Voltage-Gated Sodium Channels / Respiratory Tract Infections / Pseudomonas Aeruginosa / Ion Transport / Biochemistry and cell biology / Adenosine Triphosphate / Flagellin / ENaC / Patch-clamp and imaging techniques / Response Inhibition / Humans / Nitriles / Mice / Animals / Flagella / Calcium Signaling / Medical Physiology / Mitogen Activated Protein Kinase / Pseudomonas aeruginosa / Gram-negative bacteria / Epithelial cells / Sodium / Trachea / Voltage-Gated Sodium Channels / Respiratory Tract Infections / Pseudomonas Aeruginosa / Ion Transport / Biochemistry and cell biology / Adenosine Triphosphate / Flagellin / ENaC

Fração de ejeção e volumes do ventrículo esquerdo medidos com eco 3D e com tomografia ultra-rápida

Algorithms / Image segmentation / Linear models / Echocardiography / Humans / Close relationships / Isotopes / Nitriles / Left Ventricular Assist Device / Female / Male / Three Dimensional Imaging / Heart / Left Ventricular Dysfunction / Clinical Sciences / Dimensional / Aged / Middle Aged / Thallium / Single Photon Emission Computed Tomography / Rest / Adult / Nuclear Cardiology / Success Rate / Three Dimensional / Radiopharmaceuticals / Myocardial Perfusion Imaging / Coronary Artery Disease / Linear Regression / Ejection Fraction / X ray Computed Tomography / Heart Ventricles / Indium / Human Serum Albumin (HSA) / Close relationships / Isotopes / Nitriles / Left Ventricular Assist Device / Female / Male / Three Dimensional Imaging / Heart / Left Ventricular Dysfunction / Clinical Sciences / Dimensional / Aged / Middle Aged / Thallium / Single Photon Emission Computed Tomography / Rest / Adult / Nuclear Cardiology / Success Rate / Three Dimensional / Radiopharmaceuticals / Myocardial Perfusion Imaging / Coronary Artery Disease / Linear Regression / Ejection Fraction / X ray Computed Tomography / Heart Ventricles / Indium / Human Serum Albumin (HSA)

Physiological testosterone levels enhance chondrogenic extracellular matrix synthesis by male intervertebral disc cells in vitro, but not by mesenchymal stem cells

Extracellular Matrix / Cell Differentiation / Mesenchymal stem cells / Humans / Testosterone / Nitriles / Female / Male / Intervertebral disc / Clinical Sciences / Middle Aged / Adult / Sex Factors / Transforming Growth Factor Beta / Chondrogenesis / Triazoles / Cell Survival / Neurosciences / Mesenchymal Stromal Cells / Nitriles / Female / Male / Intervertebral disc / Clinical Sciences / Middle Aged / Adult / Sex Factors / Transforming Growth Factor Beta / Chondrogenesis / Triazoles / Cell Survival / Neurosciences / Mesenchymal Stromal Cells

A convenient synthesis of C-galactofuranosylic compounds (C-galactofuranosides)

Organic Chemistry / Nitriles / Drug Design / Hydrolysis / Carbohydrate / Furans / Methyl Ester / Biochemistry and cell biology / Furans / Methyl Ester / Biochemistry and cell biology

Flagellin of Pseudomonas aeruginosa inhibits Na+ transport in airway epithelia

Physiology / Cystic Fibrosis / Biology / Membrane Proteins / Cell Biology / Patch-clamp and imaging techniques / Response Inhibition / Humans / Nitriles / Mice / Animals / Flagella / Calcium Signaling / Medical Physiology / Mitogen Activated Protein Kinase / Pseudomonas aeruginosa / Gram-negative bacteria / Epithelial cells / Sodium / Trachea / Voltage-Gated Sodium Channels / Respiratory Tract Infections / Pseudomonas Aeruginosa / Ion Transport / Biochemistry and cell biology / Adenosine Triphosphate / Flagellin / ENaC / Patch-clamp and imaging techniques / Response Inhibition / Humans / Nitriles / Mice / Animals / Flagella / Calcium Signaling / Medical Physiology / Mitogen Activated Protein Kinase / Pseudomonas aeruginosa / Gram-negative bacteria / Epithelial cells / Sodium / Trachea / Voltage-Gated Sodium Channels / Respiratory Tract Infections / Pseudomonas Aeruginosa / Ion Transport / Biochemistry and cell biology / Adenosine Triphosphate / Flagellin / ENaC

Cyanoglucosides from Osmaronia cerasiformis (rosaceae)?

Phytochemistry / Biological Sciences / Nitriles / Plants / CHEMICAL SCIENCES

Binding of a Cyano- and Fluoro-containing Drug Bicalutamide to Cytochrome P450 46A1: UNUSUAL FEATURES AND SPECTRAL RESPONSE

Water / Kinetics / Biological Chemistry / Biological Sciences / Brain / Humans / Mutation / Nitriles / Cholesterol / Animals / Iron / Spectrophotometry / Heme / CHEMICAL SCIENCES / Cattle / Molecular Conformation / Protein Binding / Antineoplastic Agents / Site-directed Mutagenesis / Humans / Mutation / Nitriles / Cholesterol / Animals / Iron / Spectrophotometry / Heme / CHEMICAL SCIENCES / Cattle / Molecular Conformation / Protein Binding / Antineoplastic Agents / Site-directed Mutagenesis

BH3 mimetics activate multiple pro-autophagic pathways

Genetics / Membrane Proteins / Autophagy / Signal Transduction / Humans / Nitriles / Oncogene / Signal Transduction Pathway Models / Phosphorylation / Sirtuins / Clinical Sciences / Ubiquitin ligase / Acetyl CoA Carboxylase / Nitriles / Oncogene / Signal Transduction Pathway Models / Phosphorylation / Sirtuins / Clinical Sciences / Ubiquitin ligase / Acetyl CoA Carboxylase

Dipeptidyl-Peptidase IV Converts Intact B-Type Natriuretic Peptide into Its des-SerPro Form

Kinetics / Clinical Chemistry / Humans / Nitriles / Medical Biotechnology / Clinical Sciences / Protease Inhibitors / Hydrolysis / Adamantane / Atrial Natriuretic Factor / Clinical Sciences / Protease Inhibitors / Hydrolysis / Adamantane / Atrial Natriuretic Factor

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