Organic Chemistry

GLYCOLYSIS CONCERNS

Biochemistry / Organic Chemistry / Molecular Biology / Cell Biology / Medicine

SINTESIS ASETANILIDA

Organic Chemistry

New potent 5-nitrofuryl derivatives as inhibitors of Trypanosoma cruzi growth. 3D-QSAR (CoMFA) studies

Organic Chemistry / Mass Spectrometry / Modeling / Prediction / Magnetic Resonance Spectroscopy / Growth / QSAR / Animals / Quantitative Structure Activity Relationship / Hydrogen Bond / European / Trypanosoma Cruzi / Molecular Model / Three Dimensional / Trypanocidal Agents / Quntitative Thin Layer Chromatography / Chemical Synthesis / Growth / QSAR / Animals / Quantitative Structure Activity Relationship / Hydrogen Bond / European / Trypanosoma Cruzi / Molecular Model / Three Dimensional / Trypanocidal Agents / Quntitative Thin Layer Chromatography / Chemical Synthesis

5-Nitro-2-furyl derivative actives against Trypanosoma cruzi: Preliminary in vivo studies

Organic Chemistry / Mice / Female / Animals / Chagas disease / European / Trypanosoma Cruzi / Nifurtimox / Trypanocidal Agents / Murine Model / Structure activity Relationship / Acute Toxicity / Chemical Structure / European / Trypanosoma Cruzi / Nifurtimox / Trypanocidal Agents / Murine Model / Structure activity Relationship / Acute Toxicity / Chemical Structure

Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase

Organic Chemistry / Enzyme Inhibitors / Humans / Mice / Blood Pressure / Animals / Male / Drug Design / Solubility / Time Factors / Functional Group / Bioorganic and medicinal Chemistry / Structure activity Relationship / Adamantane / Physical Properties / Molecular Structure / Animals / Male / Drug Design / Solubility / Time Factors / Functional Group / Bioorganic and medicinal Chemistry / Structure activity Relationship / Adamantane / Physical Properties / Molecular Structure

Novel indoleamine 2,3-dioxygenase-1 inhibitors from a multistep in silico screen

Organic Chemistry / Enzyme Inhibitors / Humans / Drug Design / Thiourea / Enzyme / Bioorganic and medicinal Chemistry / In Silico / Protein Binding / Enzyme / Bioorganic and medicinal Chemistry / In Silico / Protein Binding

A Novel Potent Nicotinamide Phosphoribosyltransferase Inhibitor Synthesized via Click Chemistry

Organic Chemistry / Medicinal Chemistry / Enzyme Inhibitors / Autophagy / Humans / Animals / Medicinal / Structure activity Relationship / Protein Binding / Antineoplastic Agents / Alkynes / Animals / Medicinal / Structure activity Relationship / Protein Binding / Antineoplastic Agents / Alkynes

Paracelsin E, a New Peptaibol from Trichoderma saturnisporum

Biochemistry / Organic Chemistry / Natural Products / Artemia / Biological Sciences / Animals / Peptides / Trichoderma / CHEMICAL SCIENCES / Anti-Bacterial Agents / Antimicrobial Cationic Peptides / Bacillus megaterium / Microbial Sensitivity Tests / Amino Acid Sequence / Animals / Peptides / Trichoderma / CHEMICAL SCIENCES / Anti-Bacterial Agents / Antimicrobial Cationic Peptides / Bacillus megaterium / Microbial Sensitivity Tests / Amino Acid Sequence

A KINETIC DATABASE FOR ASTROCHEMISTRY (KIDA)

Organic Chemistry / Interstellar Medium / Reaction Rate

Biological Synthesis of Silver Nanoparticles from Aspergillus fumigatus

Chemistry / Analytical Chemistry / Organic Chemistry / Physical Chemistry / Materials Chemistry / Medicinal Chemistry / Chemistry Education / Natural Products Chemistry / Green Chemistry / Pharmaceutical Chemistry / Medicinal chemistry and pharmaceutical chemistry / Synthetic Organic Chemistry / Medicinal Chemistry / Chemistry Education / Natural Products Chemistry / Green Chemistry / Pharmaceutical Chemistry / Medicinal chemistry and pharmaceutical chemistry / Synthetic Organic Chemistry

Dimeric l-Dopa Derivatives as Potential Prodrugs

Organic Chemistry / Kinetics / In Vitro / Prodrugs / Humans / Animals / Plasma / Prodrug / Partition Coefficient / Levodopa / Shell Half-Life / Rats / Rat / Aqueous Solution / Hydrolysis / Chemical Stability / Drug Stability / Hydrogen-Ion Concentration / Chemical Synthesis / Physicochemical Properties / Dimerization / Enantiomer / Animals / Plasma / Prodrug / Partition Coefficient / Levodopa / Shell Half-Life / Rats / Rat / Aqueous Solution / Hydrolysis / Chemical Stability / Drug Stability / Hydrogen-Ion Concentration / Chemical Synthesis / Physicochemical Properties / Dimerization / Enantiomer

Thiosemicarbazones derived from 1-indanones as new anti-Trypanosoma cruzi agents

Organic Chemistry / Humans / Molecular docking / Chagas disease / Enzyme / Trypanosoma Cruzi / Cysteine endopeptidases / Molecular Conformation / Bioorganic and medicinal Chemistry / Trypanocidal Agents / Erythrocytes / Cysteine Proteinase Inhibitors / Trypanosoma Cruzi / Cysteine endopeptidases / Molecular Conformation / Bioorganic and medicinal Chemistry / Trypanocidal Agents / Erythrocytes / Cysteine Proteinase Inhibitors

Química Orgánica Paula Yurkanis

Quantum Physics / Chemistry / Organic Chemistry / Physical Chemistry

Dimeric l-Dopa Derivatives as Potential Prodrugs

Organic Chemistry / Kinetics / In Vitro / Prodrugs / Humans / Animals / Plasma / Prodrug / Partition Coefficient / Levodopa / Shell Half-Life / Rats / Rat / Aqueous Solution / Hydrolysis / Chemical Stability / Drug Stability / Hydrogen-Ion Concentration / Chemical Synthesis / Physicochemical Properties / Dimerization / Enantiomer / Animals / Plasma / Prodrug / Partition Coefficient / Levodopa / Shell Half-Life / Rats / Rat / Aqueous Solution / Hydrolysis / Chemical Stability / Drug Stability / Hydrogen-Ion Concentration / Chemical Synthesis / Physicochemical Properties / Dimerization / Enantiomer

Synthesis of l-(+)-3-(3-hydroxy-4-pivaloyloxybenzyl)-2,5-diketomorpholine as potential prodrug of l-dopa

Organic Chemistry / Prodrugs / Humans / Animals / Levodopa / Shell Half-Life / Rats / Shell Half-Life / Rats

Fragment-based design of 3-aminopyridine-derived amides as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT)

Organic Chemistry / Cytokines / Enzyme Inhibitors / Macromolecular X-Ray Crystallography / Humans / Amides / Cell Proliferation / Structure activity Relationship / Antineoplastic Agents / Amides / Cell Proliferation / Structure activity Relationship / Antineoplastic Agents

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