Plasmids

Neu4, a Novel Human Lysosomal Lumen Sialidase, Confers Normal Phenotype to Sialidosis and Galactosialidosis Cells

Electron Microscopy / Molecular Biology / Catalysis / Mass Spectrometry / Biological Chemistry / Confocal Microscopy / Biological Sciences / Humans / Mutation / Animals / Biological / Skin / Plasmids / Phenotype / Neuraminidase / CHEMICAL SCIENCES / Substrate Specificity / Transfection / Amino Acid Sequence / Subcellular Fractions / Lysosomes / Hydrogen-Ion Concentration / Cytoplasm / Molecular Sequence Data / Cell Membrane / Confocal Microscopy / Biological Sciences / Humans / Mutation / Animals / Biological / Skin / Plasmids / Phenotype / Neuraminidase / CHEMICAL SCIENCES / Substrate Specificity / Transfection / Amino Acid Sequence / Subcellular Fractions / Lysosomes / Hydrogen-Ion Concentration / Cytoplasm / Molecular Sequence Data / Cell Membrane

Construction of a novel expression vector in Pseudonocardia autotrophica and its application to efficient biotransformation of compactin to pravastatin, a specific HMG-CoA reductase inhibitor

Genetics / Gene expression / Genetic Engineering / Streptomyces / Industrial microbiology / Spectral analysis / Biochemical / Plasmids / Molecular cloning / Liquid Chromatography / Biotransformation / Gel electrophoresis / Base Sequence / Acetone / Lovastatin / Biochemistry and cell biology / Molecular Sequence Data / Spectral analysis / Biochemical / Plasmids / Molecular cloning / Liquid Chromatography / Biotransformation / Gel electrophoresis / Base Sequence / Acetone / Lovastatin / Biochemistry and cell biology / Molecular Sequence Data

Site-directed mutagenesis reveals a novel catalytic mechanism of Mycobacterium tuberculosis alkylhydroperoxidase C

Catalysis / Kinetics / Catalytic Mechanism / Biological Sciences / Mycobacterium tuberculosis / Mutation / Escherichia coli / Iron / Biochemical / Plasmids / Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis / Enzyme / CHEMICAL SCIENCES / Oxygen / Peroxidases / Cysteine / Alanine / Glutamine Synthetase / Site-directed Mutagenesis / Peroxiredoxins / Mutation / Escherichia coli / Iron / Biochemical / Plasmids / Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis / Enzyme / CHEMICAL SCIENCES / Oxygen / Peroxidases / Cysteine / Alanine / Glutamine Synthetase / Site-directed Mutagenesis / Peroxiredoxins

Neu4, a Novel Human Lysosomal Lumen Sialidase, Confers Normal Phenotype to Sialidosis and Galactosialidosis Cells

Electron Microscopy / Molecular Biology / Catalysis / Mass Spectrometry / Biological Chemistry / Confocal Microscopy / Biological Sciences / Humans / Mutation / Animals / Biological / Skin / Plasmids / Phenotype / Neuraminidase / CHEMICAL SCIENCES / Substrate Specificity / Transfection / Amino Acid Sequence / Human Fibroblasts / Subcellular Fractions / Lysosomes / Hydrogen-Ion Concentration / Cytoplasm / Molecular Sequence Data / Cell Membrane / Confocal Microscopy / Biological Sciences / Humans / Mutation / Animals / Biological / Skin / Plasmids / Phenotype / Neuraminidase / CHEMICAL SCIENCES / Substrate Specificity / Transfection / Amino Acid Sequence / Human Fibroblasts / Subcellular Fractions / Lysosomes / Hydrogen-Ion Concentration / Cytoplasm / Molecular Sequence Data / Cell Membrane

A Natural Plasmid Uniquely Encodes Two Biosynthetic Pathways Creating a Potent Anti-MRSA Antibiotic

Multidisciplinary / DNA sequence design / Plasmids / Marine Bacteria / PLoS one / Anti-Bacterial Agents / Microbial Sensitivity Tests / Bioactive Compound / Biosynthetic Pathways / Methicillin Resistant Staphylococcus Aureus / Molecular Structure / Pseudoalteromonas / DNA sequence / Anti-Bacterial Agents / Microbial Sensitivity Tests / Bioactive Compound / Biosynthetic Pathways / Methicillin Resistant Staphylococcus Aureus / Molecular Structure / Pseudoalteromonas / DNA sequence

Naturally Competent Acinetobacter baumannii Clinical Isolate as a Convenient Model for Genetic Studies

Genetics / Clinical Microbiology / Biological Sciences / Genetics & Microbial Biotechnology / Humans / Clinical / Plasmids / Anti-Bacterial Agents / Bacteremia / Microbial Sensitivity Tests / Acinetobacter baumannii / Intensive Care Units / Oligonucleotides / Acinetobacter Infections / Clinical / Plasmids / Anti-Bacterial Agents / Bacteremia / Microbial Sensitivity Tests / Acinetobacter baumannii / Intensive Care Units / Oligonucleotides / Acinetobacter Infections

Primary structure of the Streptomyces R61 extracellular DD-peptidase. 2. Amino acid sequence data

Kinetics / Recombinant DNA Technology / Streptomyces / Nucleic acid hybridization / Trypsin / Plasmids / Sequence / Genes / European / Molecular cloning / Amino Acids / Amino Acid Sequence / Base Sequence / Hydrolysis / Genetic Code / Biochemistry and cell biology / Plasmids / Sequence / Genes / European / Molecular cloning / Amino Acids / Amino Acid Sequence / Base Sequence / Hydrolysis / Genetic Code / Biochemistry and cell biology

A filamentous phage display system for N-linked glycoproteins

Protein Science / Protein / Polysaccharides / Mutation / Escherichia coli / P-glycoprotein / Phage display / Plasmids / Glycoproteins / Glycosylation / Glycosyltransferases / Asparagine / Campylobacter jejuni / Biochemistry and cell biology / Oligosaccharides / P-glycoprotein / Phage display / Plasmids / Glycoproteins / Glycosylation / Glycosyltransferases / Asparagine / Campylobacter jejuni / Biochemistry and cell biology / Oligosaccharides

Environmental Microbiota Represents a Natural Reservoir for Dissemination of Clinically Relevant Metallo- -Lactamases

Microbiology / Medical Microbiology / Hospitals / Pseudomonas / Plasmids / Pseudomonas aeruginosa / Integrons / Sewage / Antimicrobial agents / Pseudomonas Aeruginosa / Water Microbiology / Beta Lactamases / Pseudomonas aeruginosa / Integrons / Sewage / Antimicrobial agents / Pseudomonas Aeruginosa / Water Microbiology / Beta Lactamases

The Bacteriophage T7 Binary System Activates Transient Transgene Expression in Zebrafish (Danio rerio) Embryos

Danio rerio / Escherichia coli / Animals / Cytomegalovirus / Biochemical / Plasmids / Zebrafish / Embryos / Transgene Expression / Biochemistry and cell biology / Plasmids / Zebrafish / Embryos / Transgene Expression / Biochemistry and cell biology

Ambler Class A Extended-Spectrum  -Lactamases in Pseudomonas aeruginosa: Novel Developments and Clinical Impact

Microbiology / Medical Microbiology / Canada / Prospective studies / Humans / Escherichia coli / Klebsiella / Plasmids / Phenotype / Pseudomonas aeruginosa / Spectrum / Anti-Bacterial Agents / Antimicrobial agents / Pulsed field gel electrophoresis (PFGE) / Microbial Sensitivity Tests / Pseudomonas Aeruginosa / Escherichia Coli Infections / Beta Lactamases / Escherichia coli / Klebsiella / Plasmids / Phenotype / Pseudomonas aeruginosa / Spectrum / Anti-Bacterial Agents / Antimicrobial agents / Pulsed field gel electrophoresis (PFGE) / Microbial Sensitivity Tests / Pseudomonas Aeruginosa / Escherichia Coli Infections / Beta Lactamases

Naturally Competent Acinetobacter baumannii Clinical Isolate as a Convenient Model for Genetic Studies

Genetics / Clinical Microbiology / Biological Sciences / Genetics & Microbial Biotechnology / Humans / Clinical / Plasmids / Anti-Bacterial Agents / Bacteremia / Microbial Sensitivity Tests / Acinetobacter baumannii / Intensive Care Units / Oligonucleotides / Acinetobacter Infections / Clinical / Plasmids / Anti-Bacterial Agents / Bacteremia / Microbial Sensitivity Tests / Acinetobacter baumannii / Intensive Care Units / Oligonucleotides / Acinetobacter Infections

Horizontal spread of mer operons among Gram-positive bacteria in natural environments

Microbiology / Horizontal Gene Transfer / Multidisciplinary / Phylogeny / Mercury / Bacillus / Oxidoreductases / Microbial genetic and drug resistance / Plasmids / Gram Positive Bacteria / Natural Environment / Genetic variation / Population Study / Species Specificity / Organomercury Compounds / Bacillus / Oxidoreductases / Microbial genetic and drug resistance / Plasmids / Gram Positive Bacteria / Natural Environment / Genetic variation / Population Study / Species Specificity / Organomercury Compounds

Gram-positive and Gram-negative bacteria as carrier systems for DNA vaccines

Dendritic Cells / Biological Sciences / Cell line / Humans / Gram Positive / Animals / Listeria monocytogenes / Fishes / Vaccine / Dendritic cell / DNA vaccines / Plasmids / Gram Positive Bacteria / Gram-negative bacteria / Phagocytosis / DNA vaccine / Drug Carriers / Plasmid DNA / Animals / Listeria monocytogenes / Fishes / Vaccine / Dendritic cell / DNA vaccines / Plasmids / Gram Positive Bacteria / Gram-negative bacteria / Phagocytosis / DNA vaccine / Drug Carriers / Plasmid DNA

Probing In Vivo Trafficking of Polymer/DNA Micellar Nanoparticles Using SPECT/CT Imaging

Technology / Computed Tomography / Kinetics / Nanoparticles / Biological Sciences / DNA / Molecular / Micelles / Liver / Female / Animals / Gene transfer techniques / Plasmids / Gene Delivery / Polyethylene Glycol / Rats / Single Photon Emission Computed Tomography / Wistar Rats / Molecular Targeted Therapy / Physicochemical Properties / Polyethylene Glycols / Quantitative Image Analysis / DNA / Molecular / Micelles / Liver / Female / Animals / Gene transfer techniques / Plasmids / Gene Delivery / Polyethylene Glycol / Rats / Single Photon Emission Computed Tomography / Wistar Rats / Molecular Targeted Therapy / Physicochemical Properties / Polyethylene Glycols / Quantitative Image Analysis

Gene Delivery to Adult Neural Stem Cells

Stem Cells / Gene Therapy / Stem Cell / Gene expression / Neural stem cell / Cell Differentiation / Mice / Animals / Male / Lentivirus / Cell Transplantation / Plasmids / Neurons / Clinical Sciences / Gene Delivery / Transfection / Cell Fate / Biochemistry and cell biology / Cell Differentiation / Mice / Animals / Male / Lentivirus / Cell Transplantation / Plasmids / Neurons / Clinical Sciences / Gene Delivery / Transfection / Cell Fate / Biochemistry and cell biology
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