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Plasmodium falciparum

Plasmodium falciparum signal peptide peptidase is a promising drug target against blood stage malaria

Fluorescence Microscopy / Gene Silencing / Humans / Germ Cells / Animals / Drug Design / Endoplasmic Reticulum / ER stress / Biochemical / Protease Inhibitors / Presenilins / Plasmodium falciparum / Antimalarials / Heat Shock Proteins / Protein Conformation / Amino Acid Sequence / Erythrocytes / Drug Targeting / GFP / Carbamates / Biochemistry and cell biology / Drug Design / Endoplasmic Reticulum / ER stress / Biochemical / Protease Inhibitors / Presenilins / Plasmodium falciparum / Antimalarials / Heat Shock Proteins / Protein Conformation / Amino Acid Sequence / Erythrocytes / Drug Targeting / GFP / Carbamates / Biochemistry and cell biology

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Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target

Drug development / Multidisciplinary / Macromolecular X-Ray Crystallography / Mice / Animals / Drug Resistance / Drug Design / Plasmodium falciparum / Antimalarials / Protein Conformation / Molecular Structure / Drug Resistance / Drug Design / Plasmodium falciparum / Antimalarials / Protein Conformation / Molecular Structure

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Kinetics of B Cell Responses to Plasmodium falciparum Erythrocyte Membrane Protein 1 in Ghanaian Women Naturally Exposed to Malaria Parasites

Immunology / Ghana / Immunology of the Gut / Pregnancy / Humans / Female / Adult / Plasmodium falciparum / B Lymphocytes / Protozoan Proteins / Erythrocyte Membrane / immunoglobulin G / Female / Adult / Plasmodium falciparum / B Lymphocytes / Protozoan Proteins / Erythrocyte Membrane / immunoglobulin G

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Plasma Superoxide Dismutase-1 as a Surrogate Marker of Vivax Malaria Severity

Microscopy / Brazil / Adolescent / Biological Sciences / Inflammatory Immune Response / Humans / Brazilian Amazon / Reactive Oxygen Species / Female / Animals / Male / Plasma / Polymerase Chain Reaction / Young Adult / Disease Severity / Superoxide Dismutase / Enzyme / Middle Aged / IRT-likelihood Ratio / Adult / Patient Care / Plasmodium falciparum / Tumor necrosis factor-alpha / Prognosis / Biological markers / Clinical Presentation / Predictive value of tests / Nested PCR / Plasmodium Vivax / Humans / Brazilian Amazon / Reactive Oxygen Species / Female / Animals / Male / Plasma / Polymerase Chain Reaction / Young Adult / Disease Severity / Superoxide Dismutase / Enzyme / Middle Aged / IRT-likelihood Ratio / Adult / Patient Care / Plasmodium falciparum / Tumor necrosis factor-alpha / Prognosis / Biological markers / Clinical Presentation / Predictive value of tests / Nested PCR / Plasmodium Vivax

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Diagnosis of Placental Malaria

Microscopy / Clinical Microbiology / Biological Sciences / Pregnancy / Humans / Low Birth Weight / Placenta / Female / Animals / Clinical / Polymerase Chain Reaction / Placental Malaria / Plasmodium falciparum / Pregnant Women / Preterm Delivery / Low Birth Weight / Placenta / Female / Animals / Clinical / Polymerase Chain Reaction / Placental Malaria / Plasmodium falciparum / Pregnant Women / Preterm Delivery

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Plasma glutamine levels and falciparum malaria

Microbiology / Medical Microbiology / Disease susceptibility / Prospective studies / Humans / Child / Female / Male / Infant / Glutamine / Public health systems and services research / Plasmodium falciparum / Hematocrit / Case Control Studies / Child / Female / Male / Infant / Glutamine / Public health systems and services research / Plasmodium falciparum / Hematocrit / Case Control Studies

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Protection against experimental malaria associated with AMA-1 peptide analogue structures

Nuclear Magnetic Resonance / Membrane Proteins / Magnetic Resonance Spectroscopy / Animals / Peptides / Immune system / Plasmodium falciparum / Red blood cell / Amino Acid Profile / Protein Conformation / Protozoan Proteins / Amino Acid Sequence / Membrane Protein / Structure activity Relationship / Nuclear Overhauser Effect / Biochemistry and cell biology / Malaria Vaccines / Apical Membrane Antigen -1 / Immune system / Plasmodium falciparum / Red blood cell / Amino Acid Profile / Protein Conformation / Protozoan Proteins / Amino Acid Sequence / Membrane Protein / Structure activity Relationship / Nuclear Overhauser Effect / Biochemistry and cell biology / Malaria Vaccines / Apical Membrane Antigen -1

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PTEX is an essential nexus for protein export in malaria parasites

Malaria / Multidisciplinary / Nature / Humans / Animals / Plasmodium falciparum / Heat Shock Proteins / Protozoan Proteins / Erythrocytes / Protein Transport / Plasmodium falciparum / Heat Shock Proteins / Protozoan Proteins / Erythrocytes / Protein Transport

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HLA-A*01-Restricted Cytotoxic T-Lymphocyte Epitope from the Plasmodium falciparum Circumsporozoite Protein

Biological Sciences / Infection and immunity / Humans / Animals / Infection / Immunization / Plasmodium falciparum / Protozoan Proteins / Amino Acid Sequence / Immunization / Plasmodium falciparum / Protozoan Proteins / Amino Acid Sequence

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Applied genomics: data mining reveals species-specific malaria diagnostic targets more sensitive than 18S rRNA

Parasitology / Data Mining / Genomics / Computational Biology / Malaria / Venezuela / Tanzania / Molecular Diagnostics / Plasmodium / Clinical Microbiology / Biological Sciences / Humans / Animals / Clinical / Polymerase Chain Reaction / Plasmodium falciparum / Sensitivity and Specificity / Plasmodium Vivax / Venezuela / Tanzania / Molecular Diagnostics / Plasmodium / Clinical Microbiology / Biological Sciences / Humans / Animals / Clinical / Polymerase Chain Reaction / Plasmodium falciparum / Sensitivity and Specificity / Plasmodium Vivax

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A systematic approach to stabilizing EBA-175 RII-NG for use as a malaria vaccine

Pharmaceutical Chemistry / Biological Sciences / Animals / Vaccine / Plasmodium falciparum / Very high throughput / Protozoan Proteins / Drug Stability / Malaria Vaccines / Very high throughput / Protozoan Proteins / Drug Stability / Malaria Vaccines

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A calpain unique to alveolates is essential in Plasmodium falciparum and its knockdown reveals an involvement in pre-S-phase development

Flow Cytometry / Fluorescence Microscopy / Cell Cycle / Multidisciplinary / Western blotting / Phylogeny / Humans / Animals / Genes / Calpain / Plasmodium falciparum / Gene Disruption / Drug Targeting / Fusion Protein / Phylogeny / Humans / Animals / Genes / Calpain / Plasmodium falciparum / Gene Disruption / Drug Targeting / Fusion Protein

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Antibody responses to several malaria pre-erythrocytic antigens as a marker of malaria exposure among travelers

Immune response / Adolescent / Travel / Humans / Animals / Male / Incidence / Mosquito Control / Middle Aged / Adult / Plasmodium falciparum / Military Personnel / Enzyme Linked Immunosorbent Assay / Confidence Interval / immunoglobulin G / The American / Male / Incidence / Mosquito Control / Middle Aged / Adult / Plasmodium falciparum / Military Personnel / Enzyme Linked Immunosorbent Assay / Confidence Interval / immunoglobulin G / The American

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MalaQuick™ versus ParaSight F® as a diagnostic aid in travellers\' malaria

Microbiology / Medical Microbiology / Travel / Humans / Patient Satisfaction / Proteins / Adult / Public health systems and services research / Plasmodium falciparum / Protozoan Proteins / Blood Proteins / False Negative / Proteins / Adult / Public health systems and services research / Plasmodium falciparum / Protozoan Proteins / Blood Proteins / False Negative

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Placental Malaria-Associated Suppression of Parasite-Specific Immune Response in Neonates Has No Major Impact on Systemic CD4 T Cell Homeostasis

Inflammation / Biological Sciences / Infection and immunity / Pregnancy / Humans / Placenta / Female / Infection / Newborn Infant / Homeostasis / Adult / Plasmodium falciparum / Tumor necrosis factor-alpha / Erythrocytes / Interleukin / Placenta / Female / Infection / Newborn Infant / Homeostasis / Adult / Plasmodium falciparum / Tumor necrosis factor-alpha / Erythrocytes / Interleukin

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Cellular responses to modified Plasmodium falciparum MSP119 antigens in individuals previously exposed to natural malaria infection

Medical Microbiology / Malaria / Adolescent / Humans / Female / Male / Young Adult / Adult / Plasmodium falciparum / Glutathione Transferase / Protozoan Proteins / Amino Acid Substitution Rates / Malaria Vaccines / Male / Young Adult / Adult / Plasmodium falciparum / Glutathione Transferase / Protozoan Proteins / Amino Acid Substitution Rates / Malaria Vaccines

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