Protein Binding

Cyclic urea derivatives as potent NK1 selective antagonists

Organic Chemistry / Macromolecular X-Ray Crystallography / Animals / Urea / Fluorine / Rats / Bioorganic and medicinal Chemistry / Structure activity Relationship / Protein Binding / Biological Availability / Heterocyclic compounds / Molecular Structure / Neurokinin receptor antagonists / Motor activity / Rats / Bioorganic and medicinal Chemistry / Structure activity Relationship / Protein Binding / Biological Availability / Heterocyclic compounds / Molecular Structure / Neurokinin receptor antagonists / Motor activity

Methylomic trajectories across human fetal brain development

Schizophrenia / Network Analysis / Transcription Regulation / Brain development / Fetal development / Biological Sciences / Epigenomics / Brain / Pregnancy / Humans / Female / Male / DNA methylation / CpG islands / Cluster Analysis / Genome / Sex Factors / Organogenesis / CpG island / Protein Binding / Gene expression profiling / Temporal Change / Biological Sciences / Epigenomics / Brain / Pregnancy / Humans / Female / Male / DNA methylation / CpG islands / Cluster Analysis / Genome / Sex Factors / Organogenesis / CpG island / Protein Binding / Gene expression profiling / Temporal Change

A novel thermostable neutral proteinase from Saccharomonospora canescens

Kinetics / Fluorescence / Calcium / Enzyme Inhibitors / Sequence Analysis / Biological Sciences / Physical sciences / Temperature / Activation Energy / Zinc / Enzyme / Actinomycetales / Substrate Specificity / Molecular Mass / Atomic Absorption / Esterases / Energy Transfer / Amino Acid Sequence / Polyacrylamide Gel Electrophoresis / Protein Binding / Chelating Agents / Hydrogen-Ion Concentration / Melting Temperature / Proteolytic activity / Molecular Sequence Data / Biological Sciences / Physical sciences / Temperature / Activation Energy / Zinc / Enzyme / Actinomycetales / Substrate Specificity / Molecular Mass / Atomic Absorption / Esterases / Energy Transfer / Amino Acid Sequence / Polyacrylamide Gel Electrophoresis / Protein Binding / Chelating Agents / Hydrogen-Ion Concentration / Melting Temperature / Proteolytic activity / Molecular Sequence Data

Structural, Bioinformatic, and In Vivo Analyses of Two Treponema pallidum Lipoproteins Reveal a Unique TRAP Transporter

Molecular Biology / Computational Biology / Structural Bioinformatics / Macromolecular X-Ray Crystallography / Crystal structure / Membrane transport proteins / Lipoprotein(a) / Perforation / Analytical Ultracentrifugation / Lipoproteins / Chemical Composition / Protein Quaternary Structure / Recombinant Proteins / Protein Binding / Ligands / Biochemistry and cell biology / Membrane transport proteins / Lipoprotein(a) / Perforation / Analytical Ultracentrifugation / Lipoproteins / Chemical Composition / Protein Quaternary Structure / Recombinant Proteins / Protein Binding / Ligands / Biochemistry and cell biology

PAR-3D: a server to predict protein active site residues

Documentation / Computational Biology / Structural Genomics / Biological Sciences / Software / Environmental Sciences / Sequence alignment / Protein structure / Nucleic Acids / Proteins / Enzyme / Information Storage and Retrieval / Protein Sequence Analysis / Active site / Indexation / S100 protein family / Protein Binding / Internet / Ligands / Binding Site / Environmental Sciences / Sequence alignment / Protein structure / Nucleic Acids / Proteins / Enzyme / Information Storage and Retrieval / Protein Sequence Analysis / Active site / Indexation / S100 protein family / Protein Binding / Internet / Ligands / Binding Site

Antibacterial behaviour of Vitex negundo extract assisted ZnO nanoparticles against pathogenic bacteria

Green Chemistry / Nanomaterials / Nanoparticles / Antibacterial activity / Protein Binding

Cyclic urea derivatives as potent NK1 selective antagonists

Organic Chemistry / Macromolecular X-Ray Crystallography / Animals / Urea / Fluorine / Rats / Bioorganic and medicinal Chemistry / Structure activity Relationship / Protein Binding / Biological Availability / Heterocyclic compounds / Molecular Structure / Neurokinin receptor antagonists / Motor activity / Rats / Bioorganic and medicinal Chemistry / Structure activity Relationship / Protein Binding / Biological Availability / Heterocyclic compounds / Molecular Structure / Neurokinin receptor antagonists / Motor activity

Compartmentalized Glucose Metabolism in Pseudomonas putida Is Controlled by the PtxS Repressor

Bacteriology / Transcription Factors / Biological Sciences / Glucose / Glucose Metabolism / Differential scanning calorimetry / Pseudomonas putida / Protein Binding / Cytoplasm / DNA binding proteins / Differential scanning calorimetry / Pseudomonas putida / Protein Binding / Cytoplasm / DNA binding proteins

Two modes of recruitment of E(spl) repressors onto target genes

Immunohistochemistry / Drosophila melanogaster / Transcription Factors / Morphogenesis / Development / Biological Sciences / Animals / Proteins / Phenotype / Protein Binding / DNA binding proteins / Gene Expression Regulation / Biological Sciences / Animals / Proteins / Phenotype / Protein Binding / DNA binding proteins / Gene Expression Regulation

Tetrahymena Telomerase Is Active as a Monomer

Telomerase / Biological Sciences / Animals / Enzyme / Tetrahymena / Molecular cloning / Reverse Transcriptase / Recombinant Proteins / Protein Binding / DNA binding proteins / Dimerization / Molecular cloning / Reverse Transcriptase / Recombinant Proteins / Protein Binding / DNA binding proteins / Dimerization

The Flagellar Muramidase from the Photosynthetic Bacterium Rhodobacter sphaeroides

Bacteriology / Photosynthesis / Biological Sciences / Mutation / Rhodobacter sphaeroides / Flagella / Amino Acid Profile / Chemical Composition / Amino Acid Sequence / Cell Wall / Open Reading Frame / Protein Binding / Flagella / Amino Acid Profile / Chemical Composition / Amino Acid Sequence / Cell Wall / Open Reading Frame / Protein Binding

Novel indoleamine 2,3-dioxygenase-1 inhibitors from a multistep in silico screen

Organic Chemistry / Enzyme Inhibitors / Humans / Drug Design / Thiourea / Enzyme / Bioorganic and medicinal Chemistry / In Silico / Protein Binding / Enzyme / Bioorganic and medicinal Chemistry / In Silico / Protein Binding

The AAA ATPase p97 links peptide N-glycanase to the endoplasmic reticulum-associated E3 ligase autocrine motility factor receptor

Multidisciplinary / Cercopithecus aethiops / Sequence alignment / Mutation / Mice / Animals / Endoplasmic Reticulum / P-glycoprotein / Amino Acid Sequence / Protein Quaternary Structure / Protein Binding / Animals / Endoplasmic Reticulum / P-glycoprotein / Amino Acid Sequence / Protein Quaternary Structure / Protein Binding

A Novel Potent Nicotinamide Phosphoribosyltransferase Inhibitor Synthesized via Click Chemistry

Organic Chemistry / Medicinal Chemistry / Enzyme Inhibitors / Autophagy / Humans / Animals / Medicinal / Structure activity Relationship / Protein Binding / Antineoplastic Agents / Alkynes / Animals / Medicinal / Structure activity Relationship / Protein Binding / Antineoplastic Agents / Alkynes

Crystal structure of a mammalian phosphoinositide-specific phospholipase Cδ

Catalysis / Multidisciplinary / Nature / Macromolecular X-Ray Crystallography / Crystal structure / Humans / Animals / Enzyme / Rats / Isoenzymes / Molecular Conformation / Protein Conformation / Amino Acid Sequence / Recombinant Proteins / Protein Binding / Hydrolysis / Second Messengers / Phospholipase C / Humans / Animals / Enzyme / Rats / Isoenzymes / Molecular Conformation / Protein Conformation / Amino Acid Sequence / Recombinant Proteins / Protein Binding / Hydrolysis / Second Messengers / Phospholipase C

Crystal structure of a mammalian phosphoinositide-specific phospholipase Cδ

Catalysis / Multidisciplinary / Nature / Macromolecular X-Ray Crystallography / Crystal structure / Humans / Animals / Enzyme / Rats / Isoenzymes / Molecular Conformation / Protein Conformation / Amino Acid Sequence / Recombinant Proteins / Protein Binding / Hydrolysis / Second Messengers / Phospholipase C / Humans / Animals / Enzyme / Rats / Isoenzymes / Molecular Conformation / Protein Conformation / Amino Acid Sequence / Recombinant Proteins / Protein Binding / Hydrolysis / Second Messengers / Phospholipase C
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