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Protein Binding

NAADP mobilizes calcium from acidic organelles through two-pore channels

Calcium / Cell Biology / Multidisciplinary / Nature / Organelles / Cell line / Humans / Mice / Animals / Calcium channels / Endoplasmic Reticulum / Cell Signalling / Health Science / Calcium Signaling / Ryanodine Receptor / Chickens / Protein Binding / Hydrogen-Ion Concentration / Nicotinic acid / Cell line / Humans / Mice / Animals / Calcium channels / Endoplasmic Reticulum / Cell Signalling / Health Science / Calcium Signaling / Ryanodine Receptor / Chickens / Protein Binding / Hydrogen-Ion Concentration / Nicotinic acid

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Is Nostoc H-NOX a NO Sensor or Redox Switch?

Biochemistry / Cyanobacteria / Nitric oxide / Spectrum analysis / Protein Conformation / Protein Binding / Oxidation-Reduction / Guanylate Cyclase / Biochemistry and cell biology / Protein Binding / Oxidation-Reduction / Guanylate Cyclase / Biochemistry and cell biology

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Endosome-to-cytosol transport of viral nucleocapsids

Biochemistry / Genetics / Biophysics / Electron Microscopy / Molecular Biology / Stem Cells / Migration / MicroRNA / Cancer / Fluorescence Microscopy / Cell Cycle / Cell Biology / DNA damage / Apoptosis / Adhesion / Nature / Cytoskeleton / Signal Transduction / Transcription / Biological Sciences / Cell line / Humans / Animals / Vesicular Stomatitis Virus / Membrane Fusion / Signalling / Chromatin / Cattle / Epithelial cells / Domains / Time Factors / Viral Infection / HeLa cells / Polarity / Receptor / Zebrafish / Human Fibroblasts / Monoglycerides / Vesicle Formation / Protein Binding / Endosomes / Stem Cells / Migration / MicroRNA / Cancer / Fluorescence Microscopy / Cell Cycle / Cell Biology / DNA damage / Apoptosis / Adhesion / Nature / Cytoskeleton / Signal Transduction / Transcription / Biological Sciences / Cell line / Humans / Animals / Vesicular Stomatitis Virus / Membrane Fusion / Signalling / Chromatin / Cattle / Epithelial cells / Domains / Time Factors / Viral Infection / HeLa cells / Polarity / Receptor / Zebrafish / Human Fibroblasts / Monoglycerides / Vesicle Formation / Protein Binding / Endosomes

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miR-29a and miR-29b Contribute to Pancreatic  -Cell-Specific Silencing of Monocarboxylate Transporter 1 (Mct1)

MicroRNA / Mitochondria / Biological Sciences / RNA interference / Cell line / Molecular and cellular biology / Humans / Glucose / Insulin / Insulin Secretion / Mutation / Mice / Pancreas / Animals / DNA methylation / microRNAs / Isoenzymes / Lactate dehydrogenase / Protein Binding / Plasma Membrane / Binding Site / Oxidative Metabolism / Molecular and cellular biology / Humans / Glucose / Insulin / Insulin Secretion / Mutation / Mice / Pancreas / Animals / DNA methylation / microRNAs / Isoenzymes / Lactate dehydrogenase / Protein Binding / Plasma Membrane / Binding Site / Oxidative Metabolism

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miR-29a and miR-29b contribute to pancreatic β-cell-specific silencing of monocarboxylate transporter 1 (Mct1)

MicroRNA / Mitochondria / Biological Sciences / RNA interference / Cell line / Molecular and cellular biology / Humans / Glucose / Insulin / Insulin Secretion / Mutation / Mice / Pancreas / Animals / DNA methylation / microRNAs / Isoenzymes / Lactate dehydrogenase / Protein Binding / Plasma Membrane / Binding Site / Oxidative Metabolism / Molecular and cellular biology / Humans / Glucose / Insulin / Insulin Secretion / Mutation / Mice / Pancreas / Animals / DNA methylation / microRNAs / Isoenzymes / Lactate dehydrogenase / Protein Binding / Plasma Membrane / Binding Site / Oxidative Metabolism

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IL-1β potently stabilizes IL-6 mRNA in human astrocytes

Western blotting / miRNA / Cell line / Humans / Astrocyte / Central Nervous System / TNF / PKC / mRNA stability / Astrocytes / IL / Iso / Tumor necrosis factor-alpha / MAPK / BIOCHEMICAL PHARMACOLOGY / Protein Binding / P / UTR / Enzyme Linked Immunosorbent Assay / Interleukin / Isoproterenol / Central Nervous System / TNF / PKC / mRNA stability / Astrocytes / IL / Iso / Tumor necrosis factor-alpha / MAPK / BIOCHEMICAL PHARMACOLOGY / Protein Binding / P / UTR / Enzyme Linked Immunosorbent Assay / Interleukin / Isoproterenol

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ADAM8 as a drug target in pancreatic cancer

Membrane Proteins / Multidisciplinary / Western blotting / Signal Transduction / Humans / Mice / Animals / Cyclic peptides / Phosphorylation / Neoplasm Invasiveness / Protein Binding / Hydroxamic Acids / Molecular Targeted Therapy / Nature Communications / Extracellular Space / Matrix Metalloproteinase / Mice / Animals / Cyclic peptides / Phosphorylation / Neoplasm Invasiveness / Protein Binding / Hydroxamic Acids / Molecular Targeted Therapy / Nature Communications / Extracellular Space / Matrix Metalloproteinase

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Frontotemporal dementia and parkinsonism linked to chromosome 17: A consensus conference

Genetics / Cognitive Science / Dementia / Magnetic Resonance Imaging / Neuropathology / Molecular Genetics / Poland / Movement disorders / Genetic counseling / Temporal Lobe / Brain / Humans / Mutation / Female / Male / Differential Diagnosis / Electromyography / Life Expectancy / Pedigree / Genetic linkage analysis / Clinical Sciences / North America / Middle Aged / Cognitive impairment / Adult / Frontotemporal Dementia / X ray Computed Tomography / Protein Binding / Psychomotor Disorders / Neurosciences / Frontal Lobe / Parkinson Disease / Cognition disorders / Molecular Genetics / Poland / Movement disorders / Genetic counseling / Temporal Lobe / Brain / Humans / Mutation / Female / Male / Differential Diagnosis / Electromyography / Life Expectancy / Pedigree / Genetic linkage analysis / Clinical Sciences / North America / Middle Aged / Cognitive impairment / Adult / Frontotemporal Dementia / X ray Computed Tomography / Protein Binding / Psychomotor Disorders / Neurosciences / Frontal Lobe / Parkinson Disease / Cognition disorders

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Compartmentalized glucose metabolism in Pseudomonas putida is controlled by the PtxS repressor

Bacteriology / Transcription Factors / Biological Sciences / Glucose / Glucose Metabolism / Differential scanning calorimetry / Pseudomonas putida / Protein Binding / Cytoplasm / DNA binding proteins / Differential scanning calorimetry / Pseudomonas putida / Protein Binding / Cytoplasm / DNA binding proteins

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Kinetic Mechanism of Pyranose 2-Oxidase from Trametes multicolor

Biochemistry / Catalysis / Kinetics / Glucose / Temperature / Enzyme / Steady state / Hydrogen Peroxide / Active site / Buffers / Oxygen / Substrate Specificity / Isotope effect / Phosphates / Protein Conformation / Protein Binding / Hydrogen-Ion Concentration / Oxidation-Reduction / Flavins / Biochemistry and cell biology / Enzyme / Steady state / Hydrogen Peroxide / Active site / Buffers / Oxygen / Substrate Specificity / Isotope effect / Phosphates / Protein Conformation / Protein Binding / Hydrogen-Ion Concentration / Oxidation-Reduction / Flavins / Biochemistry and cell biology

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Probing active-site residues of pyranose 2-oxidase from Trametes multicolor by semi-rational protein design

Kinetics / Biotechnology / Industrial Biotechnology / Gene expression / Protein Engineering / Environmental Biotechnology / Biocatalysis / Protein Design / Mutation / Escherichia coli / Medical Biotechnology / Temperature / Hydrogen Bonding / Theoretical Models / Active site / Protein Secondary Structure Prediction / Buffers / Substrate Specificity / Bioreactors / Phosphates / Amino Acid Sequence / Structure activity Relationship / Recombinant Proteins / Protein Binding / Hydrogen-Ion Concentration / Site-directed Mutagenesis / Oxidation-Reduction / Environmental Biotechnology / Biocatalysis / Protein Design / Mutation / Escherichia coli / Medical Biotechnology / Temperature / Hydrogen Bonding / Theoretical Models / Active site / Protein Secondary Structure Prediction / Buffers / Substrate Specificity / Bioreactors / Phosphates / Amino Acid Sequence / Structure activity Relationship / Recombinant Proteins / Protein Binding / Hydrogen-Ion Concentration / Site-directed Mutagenesis / Oxidation-Reduction

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Streptococcus pneumoniae: Endopeptidase O (PepO): A novel C1q binding complement inhibitor

Microbiology / Immunology / Biological Chemistry / Confocal Microscopy / Innate immunity / Streptococcus pneumoniae / Western blotting / Biological Sciences / Molecular Immunology / Humans / Mutation / Plasminogen / CHEMICAL SCIENCES / Immune Evasion / Epithelial cells / Protein Binding / Bacterial Adhesion / Streptococcus pneumoniae / Western blotting / Biological Sciences / Molecular Immunology / Humans / Mutation / Plasminogen / CHEMICAL SCIENCES / Immune Evasion / Epithelial cells / Protein Binding / Bacterial Adhesion

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Comparative transcriptomic analysis of Porphyromonas gingivalis biofilm and planktonic cells

Biofilms / Transcription Regulation / DNA replication / Signal Transduction / Gene Prediction / Biological Sciences / Energy Production / Dental Plaque / Adaptive Response / Chronic Periodontitis / Global Gene Expression / Continuous Culture / Protein Binding / PORPHYROMONAS GINGIVALIS / Gene expression profiling / Differential expression / Biological Sciences / Energy Production / Dental Plaque / Adaptive Response / Chronic Periodontitis / Global Gene Expression / Continuous Culture / Protein Binding / PORPHYROMONAS GINGIVALIS / Gene expression profiling / Differential expression

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A novel fruitfly protein under developmental control degrades uracil-DNA

Drosophila melanogaster / DNA repair / DNA / Escherichia coli / Animals / Biochemical / Enzyme / Amino Acid Sequence / Protein Binding / Embryos / DNA binding proteins / Schneider / Biochemistry and cell biology / Uracil Dna Glycosylase / Biochemical / Enzyme / Amino Acid Sequence / Protein Binding / Embryos / DNA binding proteins / Schneider / Biochemistry and cell biology / Uracil Dna Glycosylase

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Human DNA polymerase iota protects cells against oxidative stress

Oxidative Stress / DNA damage / DNA repair / Biological Sciences / Cell line / Humans / Cell Death / BER / Cytoprotection / Chromatin / Hydrogen Peroxide / Human Fibroblasts / Protein Binding / DNA binding proteins / DNA Polymerase / Down-Regulation / Humans / Cell Death / BER / Cytoprotection / Chromatin / Hydrogen Peroxide / Human Fibroblasts / Protein Binding / DNA binding proteins / DNA Polymerase / Down-Regulation

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PrrC, a Sco homologue from Rhodobacter sphaeroides, possesses thiol-disulfide oxidoreductase activity

Electrochemistry / Gene expression / Signal Transduction / Insulin / Copper / Rhodobacter sphaeroides / Cytochrome c oxidase / Spectrophotometry / Thioredoxin / Bovine Serum Albumin / Protein Binding / Oxidation-Reduction / Biochemistry and cell biology / Rhodobacter sphaeroides / Cytochrome c oxidase / Spectrophotometry / Thioredoxin / Bovine Serum Albumin / Protein Binding / Oxidation-Reduction / Biochemistry and cell biology

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