Protein Binding

LXR-α selectively reprogrammes cancer cells to enter into apoptosis

Cell Cycle / Degenerative Diseases / Apoptosis / Signal Transduction / Nuclear Receptor / RNA interference / Humans / Withanolides / T lymphocytes / Neoplasms / Biological Process / Orphan Nuclear Receptors / Protein Binding / Cell Survival / Antineoplastic Agents / Ligands / Molecular and Cellular Biochemistry / Response Elements / Biochemistry and cell biology / Gene expression profiling / RNA interference / Humans / Withanolides / T lymphocytes / Neoplasms / Biological Process / Orphan Nuclear Receptors / Protein Binding / Cell Survival / Antineoplastic Agents / Ligands / Molecular and Cellular Biochemistry / Response Elements / Biochemistry and cell biology / Gene expression profiling

Lysosomal-Associated Transmembrane Protein 5 (LAPTM5) Is a Molecular Partner of CD1e

Membrane Proteins / Multidisciplinary / Humans / Melanoma / Antigen Processing / Dendritic cell / Dendrites / Solubility / Immunoprecipitation / PLoS one / Shell Half-Life / HeLa cells / Ubiquitin ligase / Transfection / Protein Binding / Endosomes / Protein Transport / Ubiquitination / Macrolides / Dendritic cell / Dendrites / Solubility / Immunoprecipitation / PLoS one / Shell Half-Life / HeLa cells / Ubiquitin ligase / Transfection / Protein Binding / Endosomes / Protein Transport / Ubiquitination / Macrolides

Small molecule Plasmodium FKBP35 inhibitor as a potential antimalaria agent

Feasibility Studies / Protein Sequence Analysis / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Amino Acid Sequence / Protein Binding / Cell Survival / Amino Acid Sequence / Protein Binding / Cell Survival

AML1/ETO sensitizes via TRAIL acute myeloid leukemia cells to the pro-apoptotic effects of hypoxia

Transcription Factors / Apoptosis / Signal Transduction / Antibodies / Acute Myeloid Leukemia / Humans / Caspase / Oxygen / Cell cycle checkpoints / Base Sequence / Protein Binding / Humans / Caspase / Oxygen / Cell cycle checkpoints / Base Sequence / Protein Binding

CHD8 regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors

Autism Spectrum Disorders / Transcription Factors / Multidisciplinary / Functional Genomics / Next generation sequencing / Software / Humans / Mutation / Animals / Genome / Risk factors / Neurons / Gene Regulatory Networks / Chromatin / Neoplasms / Zebrafish / Risk Factors / Neural Stem Cells / Protein Binding / Axons / DNA binding proteins / Gene expression profiling / Software / Humans / Mutation / Animals / Genome / Risk factors / Neurons / Gene Regulatory Networks / Chromatin / Neoplasms / Zebrafish / Risk Factors / Neural Stem Cells / Protein Binding / Axons / DNA binding proteins / Gene expression profiling

Magnesium-Induced Assembly of a Complete DNA Polymerase Catalytic Complex

Structure / Catalysis / Kinetics / Macromolecular X-Ray Crystallography / Biological Sciences / DNA / Magnesium / CHEMICAL SCIENCES / Substrate Specificity / Protein Conformation / Protein Binding / Ligands / DNA Polymerase / Nucleotides / DNA / Magnesium / CHEMICAL SCIENCES / Substrate Specificity / Protein Conformation / Protein Binding / Ligands / DNA Polymerase / Nucleotides

Acylphosphatase possesses nucleoside triphosphatase and nucleoside diphosphatase activities

Catalysis / Kinetics / Biological Sciences / Mutagenesis / Magnesium / Mutation / Animals / Biochemical / High Pressure Liquid Chromatography / CHEMICAL SCIENCES / Phosphates / Recombinant Proteins / Protein Binding / Hydrolysis / Hydrogen-Ion Concentration / Ions / Adenosine Triphosphate / Adenosine monophosphate / Adenosine Diphosphate / Mutation / Animals / Biochemical / High Pressure Liquid Chromatography / CHEMICAL SCIENCES / Phosphates / Recombinant Proteins / Protein Binding / Hydrolysis / Hydrogen-Ion Concentration / Ions / Adenosine Triphosphate / Adenosine monophosphate / Adenosine Diphosphate

Nessun Dorma, a novel centralspindlin partner, is required for cytokinesis in Drosophila spermatocytes

Drosophila melanogaster / Cell Biology / Polysaccharides / Biological Sciences / Phylogeny / Cell line / Humans / Germ Cells / Meiosis / Female / Animals / Male / Cytokinesis / Amino Acid Sequence / Protein Binding / Contractile Proteins / Cell line / Humans / Germ Cells / Meiosis / Female / Animals / Male / Cytokinesis / Amino Acid Sequence / Protein Binding / Contractile Proteins

Mycobacterium tuberculosis Rv0899 Adopts a Mixed α/β-Structure and Does Not Form a Transmembrane β-Barrel

Biochemistry / Mycobacterium tuberculosis / Protein Secondary Structure Prediction / Protein Conformation / Protein Binding / Biochemistry and cell biology

Francisella DnaK Inhibits Tissue-nonspecific Alkaline Phosphatase

Biological Chemistry / Biological Sciences / Mice / Female / Animals / Alkaline phosphatase / CHEMICAL SCIENCES / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Bacteremia / Bacterial Load / Molecular weight / Host Pathogen Interactions / Protein Binding / Adenosine Triphosphate / Tularemia / Alkaline phosphatase / CHEMICAL SCIENCES / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Bacteremia / Bacterial Load / Molecular weight / Host Pathogen Interactions / Protein Binding / Adenosine Triphosphate / Tularemia

Enhancement of Polymeric Immunoglobulin Receptor Transcytosis by Biparatopic VHH

Intelligent Transport System / Multidisciplinary / Dogs / Humans / Animals / Epitope mapping / Cell Polarity / PLoS one / Caco-2 cells / Epithelial cells / Reproducibility of Results / Caco 2 Cell / Protein Binding / Immunoglobulin / Epitope mapping / Cell Polarity / PLoS one / Caco-2 cells / Epithelial cells / Reproducibility of Results / Caco 2 Cell / Protein Binding / Immunoglobulin

Francisella DnaK Inhibits Tissue-nonspecific Alkaline Phosphatase

Biological Chemistry / Biological Sciences / Mice / Female / Animals / Alkaline phosphatase / CHEMICAL SCIENCES / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Bacteremia / Bacterial Load / Molecular weight / Host Pathogen Interactions / Protein Binding / Adenosine Triphosphate / Tularemia / Alkaline phosphatase / CHEMICAL SCIENCES / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Bacteremia / Bacterial Load / Molecular weight / Host Pathogen Interactions / Protein Binding / Adenosine Triphosphate / Tularemia

PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies

Confocal Microscopy / Transcription Factors / Signal Transduction / Biological Sciences / DNA / Organelles / Cell line / Humans / Mice / Animals / Genes / Fluorescent Antibody Technique / Protein Binding / Chromosomes / DNA binding proteins / Protein Transport / Nuclear Matrix / Gene Expression Regulation / Organelles / Cell line / Humans / Mice / Animals / Genes / Fluorescent Antibody Technique / Protein Binding / Chromosomes / DNA binding proteins / Protein Transport / Nuclear Matrix / Gene Expression Regulation

Strategies for bacterial expression of protein–peptide complexes: Application to solubilization of papillomavirus E6

Gene expression / Protein Structure and Function / Sequence alignment / Escherichia coli / Protein Aggregation / Peptides / Structure Analysis / Solubility / Protein expression and purification / Amino Acid Sequence / Protein Binding / Biochemistry and cell biology / Bovine papillomavirus / Peptides / Structure Analysis / Solubility / Protein expression and purification / Amino Acid Sequence / Protein Binding / Biochemistry and cell biology / Bovine papillomavirus

EspM2 is a RhoA guanine nucleotide exchange factor

Microbiology / Protein Folding / Medical Microbiology / Cellular microbiology / Protein Stability / Cellular / Escherichia coli / Salmonella Typhimurium / Glycoproteins / Amino Acid Substitution Rates / Protein Binding / Cellular / Escherichia coli / Salmonella Typhimurium / Glycoproteins / Amino Acid Substitution Rates / Protein Binding

A Sir2-Like Protein Participates in Mycobacterial NHEJ

Multidisciplinary / Mycobacterium / Glutathione / Sirtuins / PLoS one / Reproducibility of Results / Genetic Recombination / Repairable System / Ionizing Radiation / Microbial Viability / Protein Binding / DNA binding proteins / Infrared Rays / Reproducibility of Results / Genetic Recombination / Repairable System / Ionizing Radiation / Microbial Viability / Protein Binding / DNA binding proteins / Infrared Rays
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