Protein Conformation

SKPDB: a structural database of shikimate pathway enzymes

Relational Database / Computational Biology / Structure Based Drug Design / Biological Sciences / Protein Structure and Function / Software / Enzymes / Virtual screening / Mathematical Sciences / Drug Design / BMC Bioinformatics / Enzyme / Protein Sequence Analysis / Protein Conformation / Metabolic pathway / Amino Acid Sequence / Shikimic acid / Structural model / Software / Enzymes / Virtual screening / Mathematical Sciences / Drug Design / BMC Bioinformatics / Enzyme / Protein Sequence Analysis / Protein Conformation / Metabolic pathway / Amino Acid Sequence / Shikimic acid / Structural model

Plasmodium falciparum signal peptide peptidase is a promising drug target against blood stage malaria

Fluorescence Microscopy / Gene Silencing / Humans / Germ Cells / Animals / Drug Design / Endoplasmic Reticulum / ER stress / Biochemical / Protease Inhibitors / Presenilins / Plasmodium falciparum / Antimalarials / Heat Shock Proteins / Protein Conformation / Amino Acid Sequence / Erythrocytes / Drug Targeting / GFP / Carbamates / Biochemistry and cell biology / Drug Design / Endoplasmic Reticulum / ER stress / Biochemical / Protease Inhibitors / Presenilins / Plasmodium falciparum / Antimalarials / Heat Shock Proteins / Protein Conformation / Amino Acid Sequence / Erythrocytes / Drug Targeting / GFP / Carbamates / Biochemistry and cell biology

PGTdb: a database providing growth temperatures of prokaryotes

Bioinformatics / Cell Division / Database Management Systems / Biological Sciences / Mathematical Sciences / Archaea / Temperature / Proteins / Information Storage and Retrieval / Protein Sequence Analysis / Protein Conformation / Protein Denaturation / Archaea / Temperature / Proteins / Information Storage and Retrieval / Protein Sequence Analysis / Protein Conformation / Protein Denaturation

DC11: a novel monoclonal antibody revealing Alzheimer??s disease-specific tau epitope

Cognitive Science / Hippocampus / Humans / Mice / Female / Animals / Male / Monoclonal Antibodies / Aged / Middle Aged / Protein Conformation / Monoclonal Antibody / Neurofibrillary Tangles / Alzheimer Disease / Epitopes / Neurosciences / Animals / Male / Monoclonal Antibodies / Aged / Middle Aged / Protein Conformation / Monoclonal Antibody / Neurofibrillary Tangles / Alzheimer Disease / Epitopes / Neurosciences

Three-dimensional structural characterization of a novel Drosophila melanogaster acylphosphatase

Catalysis / Drosophila melanogaster / Biological Sciences / Humans / Expressed Sequence Tags / Animals / Physical sciences / CHEMICAL SCIENCES / Molecular cloning / Protein Conformation / Animals / Physical sciences / CHEMICAL SCIENCES / Molecular cloning / Protein Conformation

Cellular Response to DNA Damage

Radiation / DNA damage / DNA repair / Multidisciplinary / Signal Transduction / DNA / Humans / Histones / Neoplasms / Genetic Recombination / Protein Conformation / Homologous Recombination / DNA / Humans / Histones / Neoplasms / Genetic Recombination / Protein Conformation / Homologous Recombination

Lipidic phase membrane protein serial femtosecond crystallography

Technology / Membrane Proteins / Macromolecular X-Ray Crystallography / Biological Sciences / X Rays / Protein Conformation / Lipid bilayers / Membrane Protein / Protein Binding / Protein Conformation / Lipid bilayers / Membrane Protein / Protein Binding

Crystal structure of a dimeric octaheme cytochrome c3 (Mr 26000) from Desulfovibrio desulfuricans Norway

Structure / Macromolecular X-Ray Crystallography / Biological Sciences / Crystal structure / Cytochrome C / Sulfate reducing Bacteria / Structure Analysis / Heme / CHEMICAL SCIENCES / Functional Group / Protein Conformation / Amino Acid Sequence / Amino Acid Substitution Rates / Molecular Replacement / Oxidation-Reduction / Desulfovibrio / Sulfate reducing Bacteria / Structure Analysis / Heme / CHEMICAL SCIENCES / Functional Group / Protein Conformation / Amino Acid Sequence / Amino Acid Substitution Rates / Molecular Replacement / Oxidation-Reduction / Desulfovibrio

Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target

Drug development / Multidisciplinary / Macromolecular X-Ray Crystallography / Mice / Animals / Drug Resistance / Drug Design / Plasmodium falciparum / Antimalarials / Protein Conformation / Molecular Structure / Drug Resistance / Drug Design / Plasmodium falciparum / Antimalarials / Protein Conformation / Molecular Structure

Structure of the Pseudomonas aeruginosa transamidosome reveals unique aspects of bacterial tRNA-dependent asparagine biosynthesis

Molecular Evolution / Multidisciplinary / Macromolecular X-Ray Crystallography / Phylogeny / Pseudomonas aeruginosa / Pseudomonas Aeruginosa / Protein Conformation / Amino Acid Sequence / Asparagine / Pseudomonas Aeruginosa / Protein Conformation / Amino Acid Sequence / Asparagine

Amide I′−II′ 2D IR Spectroscopy Provides Enhanced Protein Secondary Structural Sensitivity

Vibration / The / Proteins / CHEMICAL SCIENCES / Amides / Protein Secondary Structure / Protein Secondary Structure Prediction / IR Spectroscopy / Protein Conformation / Protein Secondary Structure / Protein Secondary Structure Prediction / IR Spectroscopy / Protein Conformation

Protection against experimental malaria associated with AMA-1 peptide analogue structures

Nuclear Magnetic Resonance / Membrane Proteins / Magnetic Resonance Spectroscopy / Animals / Peptides / Immune system / Plasmodium falciparum / Red blood cell / Amino Acid Profile / Protein Conformation / Protozoan Proteins / Amino Acid Sequence / Membrane Protein / Structure activity Relationship / Nuclear Overhauser Effect / Biochemistry and cell biology / Malaria Vaccines / Apical Membrane Antigen -1 / Immune system / Plasmodium falciparum / Red blood cell / Amino Acid Profile / Protein Conformation / Protozoan Proteins / Amino Acid Sequence / Membrane Protein / Structure activity Relationship / Nuclear Overhauser Effect / Biochemistry and cell biology / Malaria Vaccines / Apical Membrane Antigen -1

Gambogic Acid, a Natural Product Inhibitor of Hsp90

Natural Products / Macromolecular X-Ray Crystallography / Biological Sciences / CHEMICAL SCIENCES / Natural / Protein Conformation / Cell Cycle Proteins / Benzoquinones / Triterpenes / Chaperonins / Protein Conformation / Cell Cycle Proteins / Benzoquinones / Triterpenes / Chaperonins

Antibodies as a model system for comparative model refinement

Macromolecular X-Ray Crystallography / Biological Sciences / Mathematical Sciences / Proteins / Model System / Comparative modeling / Protein Conformation / Comparative modeling / Protein Conformation

Structural Studies on Pax-8 Prd Domain/DNA Complex

Synchrotron Radiation / Macromolecular X-Ray Crystallography / DNA / Protein-DNA interaction / Humans / Transcription Factor / Comparative modeling / Protein Conformation / Amino Acid Sequence / X Ray Diffraction Analysis / Ionic Strength / Protein Binding / DNA binding proteins / Nucleic Acid Conformation / Biochemistry and cell biology / Structure Dynamics / DNA fragmentation / Transcription Factor / Comparative modeling / Protein Conformation / Amino Acid Sequence / X Ray Diffraction Analysis / Ionic Strength / Protein Binding / DNA binding proteins / Nucleic Acid Conformation / Biochemistry and cell biology / Structure Dynamics / DNA fragmentation

Novel constrained CCK-B dipeptoid antagonists derived from pipecolic acid

Organic Chemistry / Cerebral Cortex / Pancreas / Animals / Rats / Molecular Conformation / Protein Conformation / Bioorganic and medicinal Chemistry / Structure activity Relationship / Cholecystokinin / Molecular Conformation / Protein Conformation / Bioorganic and medicinal Chemistry / Structure activity Relationship / Cholecystokinin

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