Pyridines

Imidazo[1,2-a]pyridin-3-amines as potential HIV-1 non-nucleoside reverse transcriptase inhibitors

Organic Chemistry / HIV / Cell line / Humans / Selection Index / Pyridines / Bioorganic and medicinal Chemistry / Imidazoles / Structure activity Relationship / Reverse Transcriptase / Cell Survival / Molecular Structure / Pyridines / Bioorganic and medicinal Chemistry / Imidazoles / Structure activity Relationship / Reverse Transcriptase / Cell Survival / Molecular Structure

Protracted deep coma after bromazepam poisoning

Coma / Humans / Charcoal / Female / Shell Half-Life / Aged / Time Factors / Pyridines / Aged / Time Factors / Pyridines

C-Npys (S-3-nitro-2-pyridinesulfenyl) and peptide derivatives can inhibit a serine-thiol proteinase activity from Paracoccidioides brasiliensis

Fluorescence Resonance Energy Transfer / Peptides / Biochemical / Affinity chromatography / Fungal Pathogens / Pyridines / Cysteine endopeptidases / Serine Protease / Therapeutic Use / Paracoccidioides / Biochemistry and cell biology / Molecular Structure / Cysteine Proteinase Inhibitors / Pyridines / Cysteine endopeptidases / Serine Protease / Therapeutic Use / Paracoccidioides / Biochemistry and cell biology / Molecular Structure / Cysteine Proteinase Inhibitors

Pyrano-[2,3b]-pyridines as potassium channel antagonists

Organic Chemistry / Mice / Animals / Atrial Fibrillation / Pyridines / Structure activity Relationship / Cell Survival / Patch Clamp / Molecular Structure / Structure activity Relationship / Cell Survival / Patch Clamp / Molecular Structure

A novel proteasome inhibitor suppresses tumor growth via targeting both 19S proteasome deubiquitinases and 20S proteolytic peptidases

Ubiquitin / Cell line / Humans / Mice / Animals / Multiple Myeloma / Male / Boronic Acids / Protease Inhibitors / Pyridines / Organometallic Compounds / Antineoplastic Agents / Multiple Myeloma / Male / Boronic Acids / Protease Inhibitors / Pyridines / Organometallic Compounds / Antineoplastic Agents

Diazene JK-279 induces apoptosis-like cell death in human cervical carcinoma cells

Flow Cytometry / Cell Cycle / Apoptosis / Molecular Mechanics / Caspases / Humans / Cancer Therapy / Drug Resistance / Cell Death / Glutathione / Caspase / Cell nucleus / HeLa cells / Pyridines / In Vitro Toxicology / Cell Survival / Antineoplastic Agents / Humans / Cancer Therapy / Drug Resistance / Cell Death / Glutathione / Caspase / Cell nucleus / HeLa cells / Pyridines / In Vitro Toxicology / Cell Survival / Antineoplastic Agents

A synthetic molecular pentafoil knot

Supramolecular Chemistry / Mass Spectrometry / Self Assembly / NMR Spectroscopy / Magnetic Resonance Spectroscopy / Macromolecular X-Ray Crystallography / DNA / Higher Order Thinking / Amines / Iron / Hydrogen Bond / CHEMICAL SCIENCES / Pyridines / X Ray Crystallography / Chemical Synthesis / Ligands / Molecular Structure / Macromolecular X-Ray Crystallography / DNA / Higher Order Thinking / Amines / Iron / Hydrogen Bond / CHEMICAL SCIENCES / Pyridines / X Ray Crystallography / Chemical Synthesis / Ligands / Molecular Structure

Imidazo[1,2-a]pyridin-3-amines as potential HIV-1 non-nucleoside reverse transcriptase inhibitors

Organic Chemistry / HIV / Cell line / Humans / Selection Index / Pyridines / Bioorganic and medicinal Chemistry / Imidazoles / Structure activity Relationship / Reverse Transcriptase / Cell Survival / Molecular Structure / Pyridines / Bioorganic and medicinal Chemistry / Imidazoles / Structure activity Relationship / Reverse Transcriptase / Cell Survival / Molecular Structure

Potent 4-amino-5-azaindole factor VIIa inhibitors

Organic Chemistry / Pyridines / Bioorganic and medicinal Chemistry / Structure activity Relationship / Serine Protease / Tissue Factor / Molecular Structure / Tissue Factor / Molecular Structure

2-Alkyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles as novel 5-HT6 receptor agonists

Organic Chemistry / Cell line / Humans / cyclic AMP / Serotonin Receptors / Radioligand Assay / Pyridines / Structure activity Relationship / Radioligand Assay / Pyridines / Structure activity Relationship

Anion-induced reconstitution of a self-assembling system to express a chloride-binding Co10L15 pentagonal prism

Cobalt / CHEMICAL SCIENCES / Anions / Pyridines / Molecular Conformation / Chlorides

Anion-induced reconstitution of a self-assembling system to express a chloride-binding Co10L15 pentagonal prism

Cobalt / CHEMICAL SCIENCES / Anions / Pyridines / Molecular Conformation / Chlorides

Anion-induced reconstitution of a self-assembling system to express a chloride-binding Co10L15 pentagonal prism

Cobalt / CHEMICAL SCIENCES / Anions / Pyridines / Molecular Conformation / Chlorides

Cyanopyridyl containing 1,4-dihydroindeno[1,2-c]pyrazoles as potent checkpoint kinase 1 inhibitors: Improving oral biovailability

Organic Chemistry / Hydrogen / Pharmacokinetics / DNA damage / Signal Transduction / In Vitro / Protein Kinases / Mice / Animals / Bioavailability / In Vivo / Rats / Pyridines / Bioorganic and medicinal Chemistry / Pyrazoles / Cyanides / Structure activity Relationship / Chemical Synthesis / Protein Kinase Inhibitors / Molecular Structure / In Vitro / Protein Kinases / Mice / Animals / Bioavailability / In Vivo / Rats / Pyridines / Bioorganic and medicinal Chemistry / Pyrazoles / Cyanides / Structure activity Relationship / Chemical Synthesis / Protein Kinase Inhibitors / Molecular Structure

Cyanopyridyl containing 1,4-dihydroindeno[1,2- c]pyrazoles as potent checkpoint kinase 1 inhibitors: Improving oral biovailability

Organic Chemistry / Hydrogen / Pharmacokinetics / DNA damage / Signal Transduction / In Vitro / Protein Kinases / Mice / Animals / Bioavailability / In Vivo / Rats / Pyridines / Bioorganic and medicinal Chemistry / Pyrazoles / Cyanides / Structure activity Relationship / Chemical Synthesis / Protein Kinase Inhibitors / Molecular Structure / In Vitro / Protein Kinases / Mice / Animals / Bioavailability / In Vivo / Rats / Pyridines / Bioorganic and medicinal Chemistry / Pyrazoles / Cyanides / Structure activity Relationship / Chemical Synthesis / Protein Kinase Inhibitors / Molecular Structure

Cyanopyridyl containing 1,4-dihydroindeno[1,2-c]pyrazoles as potent checkpoint kinase 1 inhibitors: Improving oral biovailability

Organic Chemistry / Hydrogen / Pharmacokinetics / DNA damage / Signal Transduction / In Vitro / Protein Kinases / Mice / Animals / Bioavailability / In Vivo / Rats / Pyridines / Bioorganic and medicinal Chemistry / Pyrazoles / Cyanides / Structure activity Relationship / Chemical Synthesis / Protein Kinase Inhibitors / Molecular Structure / In Vitro / Protein Kinases / Mice / Animals / Bioavailability / In Vivo / Rats / Pyridines / Bioorganic and medicinal Chemistry / Pyrazoles / Cyanides / Structure activity Relationship / Chemical Synthesis / Protein Kinase Inhibitors / Molecular Structure

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