Quinazolines

Amino acid derived quinazolines as Rock/PKA inhibitors

Organic Chemistry / Humans / Rock / PKA / Amino Acids / Structure activity Relationship / Protein Binding / Protein Kinase Inhibitors / Quinazolines / Structure activity Relationship / Protein Binding / Protein Kinase Inhibitors / Quinazolines

Pancreatic adenocarcinoma-associated polymyositis treated with corticosteroids along with cancer specific treatment: case report

Computed Tomography / Pancreatic Cancer / Case Report / Humans / Male / Clinical Sciences / Middle Aged / Glucocorticoids / Adenocarcinoma / Quinazolines / Surgical Treatment / Polymyositis / Clinical Sciences / Middle Aged / Glucocorticoids / Adenocarcinoma / Quinazolines / Surgical Treatment / Polymyositis

Amino acid derived quinazolines as Rock/PKA inhibitors

Organic Chemistry / Humans / Amino Acids / Structure activity Relationship / Protein Binding / Protein Kinase Inhibitors / Quinazolines / Protein Kinase Inhibitors / Quinazolines

Aurora kinase inhibitor ZM447439 induces apoptosis via mitochondrial pathways

Flow Cytometry / Mitochondria / Apoptosis / Colorectal cancer / Humans / Cell Death / Kinase inhibitor / Biochemical / Time Dependent / BIOCHEMICAL PHARMACOLOGY / Aurora kinases / Mitochondrial Membrane Potential / Protein Kinase Inhibitors / Benzamides / Quinazolines / Cell Death / Kinase inhibitor / Biochemical / Time Dependent / BIOCHEMICAL PHARMACOLOGY / Aurora kinases / Mitochondrial Membrane Potential / Protein Kinase Inhibitors / Benzamides / Quinazolines

Triazoloquinazolines as a novel class of phosphodiesterase 10A (PDE10A) inhibitors

Organic Chemistry / Schizophrenia / Structure / Modeling / Macromolecular X-Ray Crystallography / In Vitro / Permeability / Animals / Phosphodiesterase Inhibitors / Rats / Molecular Model / Bioorganic and medicinal Chemistry / Benzimidazoles / Protein Binding / Chemical Synthesis / Molecular Structure / Quinazolines / In Vitro / Permeability / Animals / Phosphodiesterase Inhibitors / Rats / Molecular Model / Bioorganic and medicinal Chemistry / Benzimidazoles / Protein Binding / Chemical Synthesis / Molecular Structure / Quinazolines

Triazoloquinazolines as a novel class of phosphodiesterase 10A (PDE10A) inhibitors

Organic Chemistry / Schizophrenia / Structure / Modeling / Macromolecular X-Ray Crystallography / In Vitro / Permeability / Animals / Phosphodiesterase Inhibitors / Rats / Molecular Model / Bioorganic and medicinal Chemistry / Benzimidazoles / Protein Binding / Chemical Synthesis / Molecular Structure / Quinazolines / In Vitro / Permeability / Animals / Phosphodiesterase Inhibitors / Rats / Molecular Model / Bioorganic and medicinal Chemistry / Benzimidazoles / Protein Binding / Chemical Synthesis / Molecular Structure / Quinazolines

Aurora kinase inhibitor ZM447439 induces apoptosis via mitochondrial pathways

Flow Cytometry / Mitochondria / Apoptosis / Colorectal cancer / Humans / Cell Death / Kinase inhibitor / Biochemical / Time Dependent / BIOCHEMICAL PHARMACOLOGY / Aurora kinases / Mitochondrial Membrane Potential / Protein Kinase Inhibitors / Benzamides / Quinazolines / Cell Death / Kinase inhibitor / Biochemical / Time Dependent / BIOCHEMICAL PHARMACOLOGY / Aurora kinases / Mitochondrial Membrane Potential / Protein Kinase Inhibitors / Benzamides / Quinazolines

Disclosure of erlotinib as a multikinase inhibitor in pancreatic ductal adenocarcinoma

Humans / Mice / Animals / Neoplasia / Clinical Sciences / Transfection / Protein Kinase Inhibitors / Adenocarcinoma / Quinazolines / Transfection / Protein Kinase Inhibitors / Adenocarcinoma / Quinazolines

Serial Magnetic Resonance Spectroscopy Reveals a Direct Metabolic Effect of Cediranib in Glioblastoma

Metabolism / Cancer / Pharmacokinetics / Magnetic Resonance Spectroscopy / Humans / Glioblastoma / Female / Male / Young Adult / Aged / Middle Aged / Adult / Brain Neoplasms / Quinazolines / Glioblastoma / Female / Male / Young Adult / Aged / Middle Aged / Adult / Brain Neoplasms / Quinazolines

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