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Functionalized mesoporous silica nanoparticle-based visible light responsive controlled release delivery system
Chemistry / Inorganic Chemistry / Magnetic Materials / Targeted Drug Delivery / Nanoparticles / Transmission Electron Microscopy / Solid State Chemistry / Nanotechnology / Confocal Microscopy / Magnetic Resonance Spectroscopy / Multidisciplinary / Magnetic field / Cell Culture / Humans / Controlled release / Porosity / Medical Biotechnology / Endocytosis / Animals / Light / Folate Receptor / Drug Delivery Systems / Neurons / Hydralazine / CHEMICAL SCIENCES / Cisplatin / Doxorubicin / Spectrum / Rats / Fourier transform infrared spectroscopy / Swine / Surface Properties / Visible Light / Mesoporous / Cysteine / Langmuir / Drug Carriers / Silicon Dioxide / Delayed-Action Preparations / Hydrogen-Ion Concentration / Cell Survival / Antineoplastic Agents / Polyethylene Glycols / acrolein / Transmission Electron Microscopy / Solid State Chemistry / Nanotechnology / Confocal Microscopy / Magnetic Resonance Spectroscopy / Multidisciplinary / Magnetic field / Cell Culture / Humans / Controlled release / Porosity / Medical Biotechnology / Endocytosis / Animals / Light / Folate Receptor / Drug Delivery Systems / Neurons / Hydralazine / CHEMICAL SCIENCES / Cisplatin / Doxorubicin / Spectrum / Rats / Fourier transform infrared spectroscopy / Swine / Surface Properties / Visible Light / Mesoporous / Cysteine / Langmuir / Drug Carriers / Silicon Dioxide / Delayed-Action Preparations / Hydrogen-Ion Concentration / Cell Survival / Antineoplastic Agents / Polyethylene Glycols / acrolein
Functionalized Mesoporous Silica Nanoparticles: A Possible Strategy to Target Cancer Cells Reducing Peripheral Nervous System Uptake
Chemistry / Inorganic Chemistry / Magnetic Materials / Targeted Drug Delivery / Nanoparticles / Transmission Electron Microscopy / Solid State Chemistry / Nanotechnology / Confocal Microscopy / Magnetic Resonance Spectroscopy / Multidisciplinary / Magnetic field / Cell Culture / Humans / Controlled release / Porosity / Medical Biotechnology / Endocytosis / Animals / Light / Folate Receptor / Drug Delivery Systems / Neurons / Hydralazine / CHEMICAL SCIENCES / Cisplatin / Doxorubicin / Spectrum / Rats / Fourier transform infrared spectroscopy / Swine / Surface Properties / Visible Light / Mesoporous / Cysteine / Langmuir / Drug Carriers / Silicon Dioxide / Delayed-Action Preparations / Hydrogen-Ion Concentration / Cell Survival / Antineoplastic Agents / Polyethylene Glycols / acrolein / Transmission Electron Microscopy / Solid State Chemistry / Nanotechnology / Confocal Microscopy / Magnetic Resonance Spectroscopy / Multidisciplinary / Magnetic field / Cell Culture / Humans / Controlled release / Porosity / Medical Biotechnology / Endocytosis / Animals / Light / Folate Receptor / Drug Delivery Systems / Neurons / Hydralazine / CHEMICAL SCIENCES / Cisplatin / Doxorubicin / Spectrum / Rats / Fourier transform infrared spectroscopy / Swine / Surface Properties / Visible Light / Mesoporous / Cysteine / Langmuir / Drug Carriers / Silicon Dioxide / Delayed-Action Preparations / Hydrogen-Ion Concentration / Cell Survival / Antineoplastic Agents / Polyethylene Glycols / acrolein
Tetrahydrobenzothiophenone Derivatives as a Novel Class of Adenosine Receptor Antagonists †
Organic Chemistry / Medicinal Chemistry / Humans / Mice / Animals / Male / Rats / Structure activity Relationship / Motor activity / Male / Rats / Structure activity Relationship / Motor activity
P2Y6 Nucleotide Receptor Activates PKC to Protect 1321N1 Astrocytoma Cells Against Tumor Necrosis Factor-Induced Apoptosis
Drug interactions / Enzyme Inhibitors / Apoptosis / Molecular and cellular biology / Humans / Cellular and Molecular Neurobiology / Animals / Calcium Signaling / Astrocytes / Rats / Tumor necrosis factor-alpha / Protein isoforms / Astrocytoma / Tumor Necrosis Factor–α (TNF) / Intracellular Signaling / Neurosciences / Nucleotides / Biochemistry and cell biology / Cellular and Molecular Neurobiology / Animals / Calcium Signaling / Astrocytes / Rats / Tumor necrosis factor-alpha / Protein isoforms / Astrocytoma / Tumor Necrosis Factor–α (TNF) / Intracellular Signaling / Neurosciences / Nucleotides / Biochemistry and cell biology
Naïve coadaptive cortical control
Algorithms / Biomedical Engineering / Electroencephalography / Continuous Improvement / Neural Engineering / Kalman Filter / Dynamic Analysis / Discrimination Learning / Animals / Neuronal Plasticity / Feedback / Motor Cortex / Pitch Perception / Clinical Sciences / Computer User Interface Design / Learning Control / Rats / Auditory evoked Potentials / Neural / prosthesis Design / Auditory Cortex / Action Potentials / Signal to Noise Ratio / Neural Control / Neurosciences / Adaptive Algorithm / Kalman Filter / Dynamic Analysis / Discrimination Learning / Animals / Neuronal Plasticity / Feedback / Motor Cortex / Pitch Perception / Clinical Sciences / Computer User Interface Design / Learning Control / Rats / Auditory evoked Potentials / Neural / prosthesis Design / Auditory Cortex / Action Potentials / Signal to Noise Ratio / Neural Control / Neurosciences / Adaptive Algorithm
Water-based nanoparticulate polymeric system for protein delivery
Water / Vaccines / Biotechnology / Nanotechnology / Polymers / Multidisciplinary / Protein Engineering / Permeability / Mice / Female / Animals / Drug Delivery Systems / Rats / Buffers / Particle Size / Chickens / Time Factors / Surface Properties / Freeze Drying / Sensitivity and Specificity / Drug Stability / Hydrogen-Ion Concentration / Multidisciplinary / Protein Engineering / Permeability / Mice / Female / Animals / Drug Delivery Systems / Rats / Buffers / Particle Size / Chickens / Time Factors / Surface Properties / Freeze Drying / Sensitivity and Specificity / Drug Stability / Hydrogen-Ion Concentration
8-BuS-ATP derivatives as specific NTPDase1 inhibitors
Enzyme Inhibitors / Cercopithecus aethiops / Humans / Platelet aggregation / Mice / Animals / Rats / Species Specificity / Adenosine Triphosphate / Adenosine monophosphate / Adenosine Diphosphate / Animals / Rats / Species Specificity / Adenosine Triphosphate / Adenosine monophosphate / Adenosine Diphosphate
Developmental programming of cardiovascular disease by prenatal hypoxia
Nutrition and Dietetics / Obesity / Oxidative Stress / Causality / Cardiovascular disease / Multidisciplinary / Comorbidity / Fetal development / Birth Weight / Malnutrition / Prospective studies / Pregnancy / Humans / Anoxia / Hypertension / Renin Angiotensin Aldosterone System / Female / Animals / Male / Heart / Developmental Origins of Health and Disease / Nutrients / Risk factors / Fetal Programming / PLoS one / Maternal Nutrition / Clinical Sciences / Sex Steroids / Longitudinal Studies / Ascorbic Acid / Rats / Adult / Cardiovascular Diseases / Risk Factors / Aorta / Blood Flow Velocity / Glucocorticoids / Pulsatile Flow / Laser Doppler Flowmetry / Heart Diseases / Multidisciplinary / Comorbidity / Fetal development / Birth Weight / Malnutrition / Prospective studies / Pregnancy / Humans / Anoxia / Hypertension / Renin Angiotensin Aldosterone System / Female / Animals / Male / Heart / Developmental Origins of Health and Disease / Nutrients / Risk factors / Fetal Programming / PLoS one / Maternal Nutrition / Clinical Sciences / Sex Steroids / Longitudinal Studies / Ascorbic Acid / Rats / Adult / Cardiovascular Diseases / Risk Factors / Aorta / Blood Flow Velocity / Glucocorticoids / Pulsatile Flow / Laser Doppler Flowmetry / Heart Diseases
Chitosan nanoparticles encapsulated vesicular systems for oral immunization: preparation, in-vitro and in-vivo characterization
Pharmacy / Vaccines / Chitosan / Intestinal Mucosa / Pharmacology and Clinical pharmacy / Animals / Nanostructures / Liposomes / Saliva / Rats / Particle Size / Surface Properties / Wistar Rats / Bovine Serum Albumin / Drug Carriers / Drug Stability / Hydrogen-Ion Concentration / immunoglobulin G / Animals / Nanostructures / Liposomes / Saliva / Rats / Particle Size / Surface Properties / Wistar Rats / Bovine Serum Albumin / Drug Carriers / Drug Stability / Hydrogen-Ion Concentration / immunoglobulin G
Myosin as a potential redox-sensor: an in vitro study
Physiology / Catalysis / Western blotting / Signal Transduction / Free Radical / Muscle / Animals / Glutathione / Protein structure / Trypsin / Skeletal Muscle / Rats / Redox Regulation / Protein Conformation / In Vitro Studies / Quantum Yield / Oxidation-Reduction / Biochemistry and cell biology / Functional Dependency / Muscle / Animals / Glutathione / Protein structure / Trypsin / Skeletal Muscle / Rats / Redox Regulation / Protein Conformation / In Vitro Studies / Quantum Yield / Oxidation-Reduction / Biochemistry and cell biology / Functional Dependency
Functionalized mesoporous silica nanoparticle-based visible light responsive controlled release delivery system
Chemistry / Inorganic Chemistry / Magnetic Materials / Targeted Drug Delivery / Nanoparticles / Transmission Electron Microscopy / Solid State Chemistry / Nanotechnology / Confocal Microscopy / Magnetic Resonance Spectroscopy / Multidisciplinary / Magnetic field / Cell Culture / Humans / Controlled release / Porosity / Medical Biotechnology / Endocytosis / Animals / Light / Folate Receptor / Drug Delivery Systems / Neurons / Hydralazine / CHEMICAL SCIENCES / Cisplatin / Doxorubicin / Spectrum / Rats / Fourier transform infrared spectroscopy / Swine / Surface Properties / Visible Light / Mesoporous / Cysteine / Langmuir / Drug Carriers / Silicon Dioxide / Delayed-Action Preparations / Hydrogen-Ion Concentration / Cell Survival / Antineoplastic Agents / Polyethylene Glycols / acrolein / Transmission Electron Microscopy / Solid State Chemistry / Nanotechnology / Confocal Microscopy / Magnetic Resonance Spectroscopy / Multidisciplinary / Magnetic field / Cell Culture / Humans / Controlled release / Porosity / Medical Biotechnology / Endocytosis / Animals / Light / Folate Receptor / Drug Delivery Systems / Neurons / Hydralazine / CHEMICAL SCIENCES / Cisplatin / Doxorubicin / Spectrum / Rats / Fourier transform infrared spectroscopy / Swine / Surface Properties / Visible Light / Mesoporous / Cysteine / Langmuir / Drug Carriers / Silicon Dioxide / Delayed-Action Preparations / Hydrogen-Ion Concentration / Cell Survival / Antineoplastic Agents / Polyethylene Glycols / acrolein
NADPH Oxidase 4 Is Expressed in Pulmonary Artery Adventitia and Contributes to Hypertensive Vascular Remodeling
Enzyme Inhibitors / Extracellular Matrix / Pulmonary Hypertension / Signal Transduction / Humans / Anoxia / Reactive Oxygen Species / Mice / Animals / Male / NADPH oxidase / Clinical Sciences / Rats / Time Factors / Transfection / Cell Proliferation / Human Fibroblasts / Pulmonary Artery / Anoxia / Reactive Oxygen Species / Mice / Animals / Male / NADPH oxidase / Clinical Sciences / Rats / Time Factors / Transfection / Cell Proliferation / Human Fibroblasts / Pulmonary Artery
Reduced MMP-2 activity contributes to cardiac fibrosis in experimental diabetic cardiomyopathy
Extracellular Matrix / BASIC / Real-time RT-PCR / Diabetes mellitus / Collagen / Animals / Male / Digital Image Analysis / Fibrosis / mRna expression levels / Rats / Myocardium / Time Dependent / Diabetes complications / Western blot / Protein Expression / Transforming Growth Factor Beta / Ischemic Heart Disease / Basic Cardiology / Cardiomyopathies / Streptozotocin / Digital Image / Diabetic Rat / Left Ventricle / Matrix Metalloproteinase / Animals / Male / Digital Image Analysis / Fibrosis / mRna expression levels / Rats / Myocardium / Time Dependent / Diabetes complications / Western blot / Protein Expression / Transforming Growth Factor Beta / Ischemic Heart Disease / Basic Cardiology / Cardiomyopathies / Streptozotocin / Digital Image / Diabetic Rat / Left Ventricle / Matrix Metalloproteinase
Manganese-enhanced magnetic resonance imaging in the acute phase of the pilocarpine-induced model of epilepsy; Imagens contrastadas por manganês na fase aguda da epilepsia induzida por pilocarpina
Cognitive Science / Biomedical Engineering / Animal Behavior / Depression / Schizophrenia / Kinetics / Magnetic Resonance Imaging / Imaging / MRI / Multidisciplinary / Prefrontal Cortex / Manganese / Molecular Neurobiology / Brain Mapping / Humans / Fasting / Mice / Hypothalamus / Blood brain barrier / Female / Animals / Spinal Cord / Neuroimage / Male / Temporal Lobe Epilepsy / Heart / Hallucinogens / Mental Disorders / Brain Ischemia / Risk factors / Neurons / Epilepsia / Behavioral Animal Models / Clinical Sciences / Dentate Gyrus / Pituitary Gland / Biological systems / Early Detection / Image Enhancement / Rats / Pilocarpine / Animal models / Reproducibility of Results / Wistar Rats / Risk Factors / Amphetamines / Manganese Compounds / Sensitivity and Specificity / Thoracic Vertebrae / Spinal Cord Injuries / Ligands / Neurosciences / Contrast Media / Interferon Alpha / Motor activity / Chlorides / Magnetic resonance image / Kinetics / Magnetic Resonance Imaging / Imaging / MRI / Multidisciplinary / Prefrontal Cortex / Manganese / Molecular Neurobiology / Brain Mapping / Humans / Fasting / Mice / Hypothalamus / Blood brain barrier / Female / Animals / Spinal Cord / Neuroimage / Male / Temporal Lobe Epilepsy / Heart / Hallucinogens / Mental Disorders / Brain Ischemia / Risk factors / Neurons / Epilepsia / Behavioral Animal Models / Clinical Sciences / Dentate Gyrus / Pituitary Gland / Biological systems / Early Detection / Image Enhancement / Rats / Pilocarpine / Animal models / Reproducibility of Results / Wistar Rats / Risk Factors / Amphetamines / Manganese Compounds / Sensitivity and Specificity / Thoracic Vertebrae / Spinal Cord Injuries / Ligands / Neurosciences / Contrast Media / Interferon Alpha / Motor activity / Chlorides / Magnetic resonance image
GDNF-deprived sympathetic neurons die via a novel nonmitochondrial pathway
Cell Biology / Mitochondria / Biological Sciences / Caspases / Humans / Animals / Cell Death / Cytochrome C / Glial Cell / Proteins / Neurons / Rats / The cell / Sympathetic Nervous System / Nerve Growth Factor / Cell Survival / Animals / Cell Death / Cytochrome C / Glial Cell / Proteins / Neurons / Rats / The cell / Sympathetic Nervous System / Nerve Growth Factor / Cell Survival
Diet-Induced Ketosis Does Not Cause Cerebral Acidosis
Brain / Ketosis / Animals / Male / Epilepsia / Clinical Sciences / Rats / Dietary Carbohydrates / Wistar Rats / Acidosis / Hydrogen-Ion Concentration / Ketone Bodies / Neurosciences / Gamma-Aminobutyric Acid / Brain Diseases / Dietary fats / Clinical Sciences / Rats / Dietary Carbohydrates / Wistar Rats / Acidosis / Hydrogen-Ion Concentration / Ketone Bodies / Neurosciences / Gamma-Aminobutyric Acid / Brain Diseases / Dietary fats
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