Trypanocidal Agents

Arylfurans as potential Trypanosoma cruzi trypanothione reductase inhibitors

Medical Microbiology / Enzyme Inhibitors / Mice / Animals / Male / Chagas disease / Total Synthesis / Trypanosoma Cruzi / Trypanocidal Agents / Structure activity Relationship / Furans / Chagas disease / Total Synthesis / Trypanosoma Cruzi / Trypanocidal Agents / Structure activity Relationship / Furans

Co-infection Trypanosoma cruzi/HIV: Systematic review (1980 - 2010) | Coinfecção Trypanosoma cruzi/HIV: Revisão sistemática (1980 - 2010)

Humans / Chronic Disease / Female / Male / Coinfection / Young Adult / Chagas disease / Aged / Middle Aged / Adult / Immunocompromised host / Highly Active Antiretroviral Therapy / Trypanocidal Agents / Young Adult / Chagas disease / Aged / Middle Aged / Adult / Immunocompromised host / Highly Active Antiretroviral Therapy / Trypanocidal Agents

Trypanocidal Withanolides and Withanolide Glycosides from Dunalia brachyacantha

Natural Products / Mass Spectrometry / Bolivia / Medicinal Plants / Leishmania / Magnetic Resonance Spectroscopy / Biological Sciences / Animals / Bacteria / Withanolides / Plant Roots / CHEMICAL SCIENCES / Trypanosoma Cruzi / Natural / Solanaceae / Microbial Sensitivity Tests / Trypanocidal Agents / Disaccharides / Ergosterol / Lactones / Glycosides / Plant Leaves / Magnetic Resonance Spectroscopy / Biological Sciences / Animals / Bacteria / Withanolides / Plant Roots / CHEMICAL SCIENCES / Trypanosoma Cruzi / Natural / Solanaceae / Microbial Sensitivity Tests / Trypanocidal Agents / Disaccharides / Ergosterol / Lactones / Glycosides / Plant Leaves

Tratamento da fase crônica da doença de Chagas com nifurtimox associado a corticóide

Treatment Outcome / Humans / Chronic Disease / Female / Animals / Male / Follow-up studies / Chagas disease / Middle Aged / Adult / Combination drug therapy / Nifurtimox / Trypanocidal Agents / Glucocorticoids / Male / Follow-up studies / Chagas disease / Middle Aged / Adult / Combination drug therapy / Nifurtimox / Trypanocidal Agents / Glucocorticoids

Recomendações para diagnóstico, tratamento e acompanhamento da co-infecção Trypanosoma cruzi: vírus da imunodeficiência humana

Brazil / Pregnancy / Humans / Female / Animals / Follow-up studies / Chagas disease / Trypanosoma Cruzi / Nifurtimox / Trypanocidal Agents / Follow-up studies / Chagas disease / Trypanosoma Cruzi / Nifurtimox / Trypanocidal Agents

Trypanocidal Diarylheptanoids from Aframomum letestuianum

Natural Products / Cameroon / Medicinal Plants / Biological Sciences / Animals / Zingiberaceae / CHEMICAL SCIENCES / Seeds / Trypanosoma brucei brucei / Natural / Trypanocidal Agents / Diarylheptanoids / Molecular Structure / Zingiberaceae / CHEMICAL SCIENCES / Seeds / Trypanosoma brucei brucei / Natural / Trypanocidal Agents / Diarylheptanoids / Molecular Structure

Naphthoquinoidal [1,2,3]-triazole, a new structural moiety active against Trypanosoma cruzi

Organic Chemistry / Drug development / Macromolecular X-Ray Crystallography / Animals / Naphthoquinones / Chagas disease / European / Hydrogen Bonding / Trypanosoma Cruzi / Trypanocidal Agents / Triazoles / Structure activity Relationship / Cations / Molecular Structure / Chagas disease / European / Hydrogen Bonding / Trypanosoma Cruzi / Trypanocidal Agents / Triazoles / Structure activity Relationship / Cations / Molecular Structure

A Novel Antiprotozoal Aminosteroid from Saracha punctata

Natural Products / Medicinal Plants / Biological Sciences / Animals / CHEMICAL SCIENCES / Trypanosoma Cruzi / Antimalarials / Natural / Trypanocidal Agents / Plasmodium berghei / Trypanosoma Cruzi / Antimalarials / Natural / Trypanocidal Agents / Plasmodium berghei

Trypanocidal Withanolides and Withanolide Glycosides from Dunalia brachyacantha

Natural Products / Mass Spectrometry / Bolivia / Medicinal Plants / Leishmania / Magnetic Resonance Spectroscopy / Biological Sciences / Animals / Bacteria / Withanolides / Plant Roots / CHEMICAL SCIENCES / Trypanosoma Cruzi / Natural / Solanaceae / Microbial Sensitivity Tests / Trypanocidal Agents / Disaccharides / Ergosterol / Lactones / Glycosides / Plant Leaves / Magnetic Resonance Spectroscopy / Biological Sciences / Animals / Bacteria / Withanolides / Plant Roots / CHEMICAL SCIENCES / Trypanosoma Cruzi / Natural / Solanaceae / Microbial Sensitivity Tests / Trypanocidal Agents / Disaccharides / Ergosterol / Lactones / Glycosides / Plant Leaves

Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase

Organic Chemistry / Medicinal Chemistry / Macromolecular X-Ray Crystallography / Animals / Trypanosoma brucei / Trypanosoma brucei brucei / Trypanocidal Agents / Amino Acid Sequence / Quinolines / Structure activity Relationship / Ligands / Molecular Structure / Trypanosoma brucei brucei / Trypanocidal Agents / Amino Acid Sequence / Quinolines / Structure activity Relationship / Ligands / Molecular Structure

Albumin Nitrosylated by Activated Macrophages Possesses Antiparasitic Effects Neutralized by Anti-NO-Acetylated-Cysteine Antibodies

Immunology / Immunology of the Gut / Antibodies / Mice / Nitric oxide / Female / Animals / Trypanosoma / Nitrosation / Trypanocidal Agents / N-Acetylcysteine / Serum albumin / Female / Animals / Trypanosoma / Nitrosation / Trypanocidal Agents / N-Acetylcysteine / Serum albumin

Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase

Organic Chemistry / Medicinal Chemistry / Macromolecular X-Ray Crystallography / Animals / Trypanosoma brucei / Trypanosoma brucei brucei / Trypanocidal Agents / Amino Acid Sequence / Quinolines / Structure activity Relationship / Ligands / Molecular Structure / Trypanosoma brucei brucei / Trypanocidal Agents / Amino Acid Sequence / Quinolines / Structure activity Relationship / Ligands / Molecular Structure

Naphthoquinoidal [1,2,3]-triazole, a new structural moiety active against Trypanosoma cruzi

Organic Chemistry / Treatment / Drug development / Macromolecular X-Ray Crystallography / In Vitro / Animals / Naphthoquinones / Chagas disease / European / Hydrogen Bonding / Trypanosoma Cruzi / Trypanocidal Agents / Triazoles / Structure activity Relationship / Cations / Chemical Synthesis / Molecular Structure / Animals / Naphthoquinones / Chagas disease / European / Hydrogen Bonding / Trypanosoma Cruzi / Trypanocidal Agents / Triazoles / Structure activity Relationship / Cations / Chemical Synthesis / Molecular Structure

Biological characterization of a beta-galactosidase expressing clone of Trypanosoma cruzi CL strain

Medical Microbiology / Cercopithecus aethiops / Mice / Animals / Trypanosoma Cruzi / Nifurtimox / Trypanocidal Agents / Vero cells / Nifurtimox / Trypanocidal Agents / Vero cells

In Vitro Trypanocidal Activity of Triterpenes from Miconia Species

Complementary and Alternative Medicine / Plant Biology / Phytotherapy / Humans / Animals / Melastomataceae / Chagas disease / Plant extracts / Trypanosoma Cruzi / Trypanocidal Agents / Medicinal Plant / Planta / Triterpenes / Melastomataceae / Chagas disease / Plant extracts / Trypanosoma Cruzi / Trypanocidal Agents / Medicinal Plant / Planta / Triterpenes

A Novel Antiprotozoal Aminosteroid from Saracha punctata

Natural Products / Medicinal Plants / Biological Sciences / Animals / CHEMICAL SCIENCES / Trypanosoma Cruzi / Antimalarials / Natural / Trypanocidal Agents / Plasmodium berghei / Trypanosoma Cruzi / Antimalarials / Natural / Trypanocidal Agents / Plasmodium berghei

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