Commentary to “Pediatric hemorrhagic cystitis” by Decker DB, Karam JA, Wilcox DT. J Pediatr Urol 2009;5:254–64

May 26, 2017 | Autor: Imran Mushtaq | Categoria: Pediatric Urology, Humans, Child, Pediatric, Hemorrhage, Hematopoietic Stem Cell Transplantation
Share Embed


Descrição do Produto

Journal of Pediatric Urology (2010) 6, 98

Commentary to ‘‘Pediatric hemorrhagic cystitis’’ by Decker DB, Karam JA, Wilcox DT. J Pediatr Urol 2009;5:254e64 Sotirios Bogris, Navroop S. Johal*, Imran Mushtaq Department of Paediatric Urology, Great Ormond Street Hospital for Children NHS Trust, London WC1N 3JH, UK Received 28 August 2009; accepted 1 September 2009 We congratulate the authors on their efforts to identify an evidence-based treatment for haemorrhagic cystitis in the bone marrow transplantation population. Haemorrhagic cystitis is a life-threatening complication of bone marrow transplantation, chemotherapy and radiation therapy, and is a major management challenge. While there are numerous reports of successful treatment in the adult literature, there is a relative paucity of information in the paediatric population. Bladder irrigation with 1% alum solution bladder has been shown to be a successful form of treatment in carefully selected adult patients [1]. There are limited reports of its successful use in the paediatric population. We recently reported a 9-year-old girl post bone marrow transplant with haemorrhagic cystitis [2]. The alum irrigation resolved the haemorrhagic cystitis; however, the patient developed aluminium neurotoxicity manifesting as confusion and agitation. The serum aluminum levels were raised, with a maximum of 27 mg/L (normal
Lihat lebih banyak...

Comentários

Copyright © 2017 DADOSPDF Inc.