Osteomyelitis and Discospondylitis due to Scedosporium Apiospermum in a Dog

Journal of Veterinary Diagnostic Investigation http://vdi.sagepub.com/

Osteomyelitis and Discospondylitis due to Scedosporium Apiospermum in a Dog Christophe Hugnet, Beatrice Marrou, Claire Dally and Jacques Guillot J VET Diagn Invest 2009 21: 120 DOI: 10.1177/104063870902100119 The online version of this article can be found at: http://vdi.sagepub.com/content/21/1/120

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J Vet Diagn Invest 21:120–123 (2009)

Osteomyelitis and discospondylitis due to Scedosporium apiospermum in a dog Christophe Hugnet,1 Beatrice Marrou, Claire Dally, Jacques Guillot Abstract. A 6-year-old, 30-kg, female German Shepherd Dog, living in a leishmaniasis enzootic area, was presented with a severe rear limb motor disorder and a medical history of acute onset of fever. Routine hematology indicated neutrophilia. Spinal survey radiographs were consistent with osteomyelitis and discospondylitis. Because of the poor clinical prognosis and the painful nature of the lesions, the dog was euthanized at the owners’ request. At necropsy, T13-L1 vertebrae had large areas of necrosis within the vertebral bodies. Histopathological findings were consistent with chronic, severe, fungal osteomyelitis and discospondylitis. Polymerase chain reaction identified Scedosporium apiospermum, a eutrophic filamentous fungus now recognized as an emerging agent of severe infections in immunosuppressed human patients. Key words:

Discospondylitis; dogs; osteomyelitis; polymerase chain reaction; Scedosporium apiospermum.