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Human endogenous retrovirus (HERV-K) reverse transcriptase as a breast cancer prognostic marker

Breast Cancer / Confocal Microscopy / Endogenous Retroviruses / Biopsy / Humans / Mutation / Clinical Sciences / Active site / Carcinoma / Breast carcinoma / Prognosis / Reverse Transcriptase / Recombinant Proteins / Enzymatic Activity / Overall Survival / DNA Polymerase / Breast Cancer Cells / Mutation / Clinical Sciences / Active site / Carcinoma / Breast carcinoma / Prognosis / Reverse Transcriptase / Recombinant Proteins / Enzymatic Activity / Overall Survival / DNA Polymerase / Breast Cancer Cells

A single sequence change destabilizes the influenza virus neuraminidase tetramer

Electron Microscopy / Kinetics / Medical Microbiology / Virology / Crystallization / Enzyme Inhibitors / Macromolecular X-Ray Crystallography / Influenza virus / Biological Sciences / X Rays / Glutamate / Humans / Computer Simulation / Animals / Electron Density / Enzyme / Neuraminidase / Active site / Protein Secondary Structure Prediction / Substrate Specificity / influenza A virus / Amino Acid Profile / Antiviral / Guanidines / Enzymatic Activity / Sialic Acids / Dimerization / Zanamivir / Electron Microscope / Enzyme Inhibitors / Macromolecular X-Ray Crystallography / Influenza virus / Biological Sciences / X Rays / Glutamate / Humans / Computer Simulation / Animals / Electron Density / Enzyme / Neuraminidase / Active site / Protein Secondary Structure Prediction / Substrate Specificity / influenza A virus / Amino Acid Profile / Antiviral / Guanidines / Enzymatic Activity / Sialic Acids / Dimerization / Zanamivir / Electron Microscope

Catalytic biofunctional membranes containing site-specifically immobilized enzyme arrays: a review

Engineering / Chemical Engineering / Molecular Biology / Membrane Science / Kinetics / Enzyme / CHEMICAL SCIENCES / Active site / Gene fusion / Site-directed Mutagenesis / Binding Site / Membrane Reactor / Electron Paramagnetic Resonance / Enzyme / CHEMICAL SCIENCES / Active site / Gene fusion / Site-directed Mutagenesis / Binding Site / Membrane Reactor / Electron Paramagnetic Resonance

MEROPS: the peptidase database

Biological Sciences / Environmental Sciences / Humans / Sequence alignment / Mice / Animals / Nucleic Acids / Computer User Interface Design / Protein Sequence Analysis / Active site / Protease Inhibitors / Internet / Hierarchical Classification / Animals / Nucleic Acids / Computer User Interface Design / Protein Sequence Analysis / Active site / Protease Inhibitors / Internet / Hierarchical Classification

Cytochrome P450 biosensors—a review

Analytical Chemistry / Biomedical Engineering / Electrochemistry / Environmental Monitoring / Nanotechnology / Pharmaceutical industry / Clinical Practice / Electron Transfer / Surface plasmon resonance / Enzyme / Active site / Electrochemical Properties / Electrodes / Modified Electrode / Equipment Design / Biosensing Techniques / Pharmaceutical industry / Clinical Practice / Electron Transfer / Surface plasmon resonance / Enzyme / Active site / Electrochemical Properties / Electrodes / Modified Electrode / Equipment Design / Biosensing Techniques

Human endogenous retrovirus (HERV-K) reverse transcriptase as a breast cancer prognostic marker

Breast Cancer / Confocal Microscopy / Endogenous Retroviruses / Biopsy / Humans / Mutation / Neoplasia / Clinical Sciences / Active site / Carcinoma / Breast carcinoma / Prognosis / Reverse Transcriptase / Recombinant Proteins / Enzymatic Activity / Overall Survival / DNA Polymerase / Breast Cancer Cells / Mutation / Neoplasia / Clinical Sciences / Active site / Carcinoma / Breast carcinoma / Prognosis / Reverse Transcriptase / Recombinant Proteins / Enzymatic Activity / Overall Survival / DNA Polymerase / Breast Cancer Cells

Biochemical Characterization of Cytokinin Oxidases/Dehydrogenases from Arabidopsis thaliana Expressed in Nicotiana tabacum L

Plant Biology / Arabidopsis thaliana / Plant growth / Comparative Analysis / Plant Growth Regulation / Enzyme / Nicotiana Tabacum / Active site / Substrate Specificity / Reaction Rate / Enzymatic Activity / Nucleotides / Enzyme / Nicotiana Tabacum / Active site / Substrate Specificity / Reaction Rate / Enzymatic Activity / Nucleotides

Eosin B as a Novel Antimalarial Agent for Drug-Resistant Plasmodium falciparum

Microbiology / Medical Microbiology / Cell Culture / Toxoplasma gondii / Cell line / Humans / Animals / Drug Resistance / Life Cycle / Enzyme / Mode of action / Research Needs / Active site / Thioredoxin / Plasmodium falciparum / Antimalarials / Antimicrobial agents / Multienzyme complexes / Human Fibroblasts / Glutathione Reductase / Thioredoxin reductase / Dihydrofolate Reductase / Humans / Animals / Drug Resistance / Life Cycle / Enzyme / Mode of action / Research Needs / Active site / Thioredoxin / Plasmodium falciparum / Antimalarials / Antimicrobial agents / Multienzyme complexes / Human Fibroblasts / Glutathione Reductase / Thioredoxin reductase / Dihydrofolate Reductase

Co-catalytic metallopeptidases as pharmaceutical targets

Catalysis / Amyotrophic Lateral Sclerosis / Catalytic Mechanism / Tissue repair / Glutamate / Humans / Animals / Enzyme / Active site / Protease Inhibitors / Protein Degradation / Drug Therapy / Amino Acid Profile / Carboxypeptidases / Reaction Mechanism / Bacterial Infection / Cell Cycle Control / Biochemistry and cell biology / Humans / Animals / Enzyme / Active site / Protease Inhibitors / Protein Degradation / Drug Therapy / Amino Acid Profile / Carboxypeptidases / Reaction Mechanism / Bacterial Infection / Cell Cycle Control / Biochemistry and cell biology

Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD+

Biological Sciences / Crystal structure / Humans / Phosphorylation / Enzyme / Active site / Protein Conformation / NAD / Structural Similarity Index / Life Span / Nicotinic acid / Nucleotides / Active site / Protein Conformation / NAD / Structural Similarity Index / Life Span / Nicotinic acid / Nucleotides

Amphitrite ornata, a Marine Worm, Contains Two Dehaloperoxidase Genes

Technology / Environmental Sciences / Marine BioTechnology / Polymerase Chain Reaction / Active site / Genomic DNA / Marine Environment / Substrate Specificity / Amino Acid Profile / Amino Acid Sequence / Organic Compound / Genomic DNA / Marine Environment / Substrate Specificity / Amino Acid Profile / Amino Acid Sequence / Organic Compound

Reagentless oxidoreductase sensors

Analytical Chemistry / Biomedical Engineering / Nanotechnology / Enzyme / Active site / Charge Transport / Reaction Mechanism / Charge Transport / Reaction Mechanism

Structural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1

Kinetics / Macromolecular X-Ray Crystallography / Biological Sciences / Crystal structure / Humans / Endoplasmic Reticulum / Antigen Presentation / Special functions / CHEMICAL SCIENCES / Active site / Substrate Specificity / Structure activity Relationship / Conformational Change / Antigens / MHC class I / Endoplasmic Reticulum / Antigen Presentation / Special functions / CHEMICAL SCIENCES / Active site / Substrate Specificity / Structure activity Relationship / Conformational Change / Antigens / MHC class I

Eosin B as a Novel Antimalarial Agent for Drug-Resistant Plasmodium falciparum

Microbiology / Medical Microbiology / Cell Culture / Toxoplasma gondii / Cell line / Humans / Animals / Drug Resistance / Life Cycle / Enzyme / Mode of action / Research Needs / Active site / Thioredoxin / Plasmodium falciparum / Antimalarials / Antimicrobial agents / Multienzyme complexes / Human Fibroblasts / Glutathione Reductase / Thioredoxin reductase / Dihydrofolate Reductase / Humans / Animals / Drug Resistance / Life Cycle / Enzyme / Mode of action / Research Needs / Active site / Thioredoxin / Plasmodium falciparum / Antimalarials / Antimicrobial agents / Multienzyme complexes / Human Fibroblasts / Glutathione Reductase / Thioredoxin reductase / Dihydrofolate Reductase

Arabidopsis thaliana VTC4 Encodes L-Galactose-1-P Phosphatase, a Plant Ascorbic Acid Biosynthetic Enzyme

Genetics / Biological Chemistry / Arabidopsis thaliana / Biological Sciences / Phylogeny / Humans / Mutation / vitamin C / Animals / Biological / Genetic Map / Arabidopsis / Enzyme / CHEMICAL SCIENCES / Ascorbic Acid / Active site / Amino Acid Profile / Amino Acid Sequence / Base Sequence / Mannose / Galactose Binding / Myo-inositol / Molecular Sequence Data / Humans / Mutation / vitamin C / Animals / Biological / Genetic Map / Arabidopsis / Enzyme / CHEMICAL SCIENCES / Ascorbic Acid / Active site / Amino Acid Profile / Amino Acid Sequence / Base Sequence / Mannose / Galactose Binding / Myo-inositol / Molecular Sequence Data

Probing active-site residues of pyranose 2-oxidase from Trametes multicolor by semi-rational protein design

Kinetics / Biotechnology / Industrial Biotechnology / Gene expression / Protein Engineering / Environmental Biotechnology / Biocatalysis / Biological Sciences / Protein Design / Mutation / Escherichia coli / Medical Biotechnology / Temperature / Hydrogen Bonding / Theoretical Models / Active site / Protein Secondary Structure Prediction / Buffers / Substrate Specificity / Bioreactors / Phosphates / Amino Acid Sequence / Structure activity Relationship / Recombinant Proteins / Protein Binding / Galactose Binding / Hydrogen-Ion Concentration / Site-directed Mutagenesis / Oxidation-Reduction / Molecular Sequence Data / Environmental Biotechnology / Biocatalysis / Biological Sciences / Protein Design / Mutation / Escherichia coli / Medical Biotechnology / Temperature / Hydrogen Bonding / Theoretical Models / Active site / Protein Secondary Structure Prediction / Buffers / Substrate Specificity / Bioreactors / Phosphates / Amino Acid Sequence / Structure activity Relationship / Recombinant Proteins / Protein Binding / Galactose Binding / Hydrogen-Ion Concentration / Site-directed Mutagenesis / Oxidation-Reduction / Molecular Sequence Data
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