Apoptosis

3-O-[N-(p-fluorobenzenesulfonyl)-carbamoyl]-oleanolic acid, a semisynthetic analog of oleanolic acid, induces apoptosis in breast cancer cells

Apoptosis / Caspases / Humans / Female / Caspase / Cell Proliferation / Cell Survival / Antineoplastic Agents / Oleanolic acid / Estrogen receptor alpha / Fas Ligand / Cell Proliferation / Cell Survival / Antineoplastic Agents / Oleanolic acid / Estrogen receptor alpha / Fas Ligand

Genista sessilifolia DC. extracts induce apoptosis across a range of cancer cell lines

Flow Cytometry / Cell Cycle / Apoptosis / Cell Differentiation / Humans / Methanol / High Pressure Liquid Chromatography / Caspase / Plant extracts / HeLa cells / Genistein / Cell Proliferation / Biochemistry and cell biology / Methanol / High Pressure Liquid Chromatography / Caspase / Plant extracts / HeLa cells / Genistein / Cell Proliferation / Biochemistry and cell biology

RGDechi-hCit: αvβ3 Selective Pro-Apoptotic Peptide as Potential Carrier for Drug Delivery into Melanoma Metastatic Cells

Apoptosis / Multidisciplinary / Humans / Melanoma / Peptides / PLoS one / HeLa cells / Cell Proliferation / Drug Carriers / Clathrin / PLoS one / HeLa cells / Cell Proliferation / Drug Carriers / Clathrin

Cardenolide Glycosides from Pergularia tomentosa and Their Proapoptotic Activity in Kaposi\'s Sarcoma Cells

Natural Products / Egypt / Pharmacognosy / Medicinal Plants / Cytotoxicity / Apoptosis / Structural Analysis / Biological Sciences / Cell line / Humans / ROOT / Cell Death / Plant Roots / CHEMICAL SCIENCES / Apoptose / Isolation / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Natural / Asclepiadaceae / Biological activity / Glycosides / Apoptosis / Structural Analysis / Biological Sciences / Cell line / Humans / ROOT / Cell Death / Plant Roots / CHEMICAL SCIENCES / Apoptose / Isolation / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Natural / Asclepiadaceae / Biological activity / Glycosides

A Novel Immunocytolytic Factor Secreted by Pancreatic Adenocarcinoma

Apoptosis / Pancreatic Cancer / Spleen / Cell line / Humans / Mice / Female / Animals / Cell Death / Clinical Sciences / Western blot / Mechanism of action / Lymphocytes / Surgical / Culture Media / Adenocarcinoma / Immunoblotting / Fas Ligand / Mice / Female / Animals / Cell Death / Clinical Sciences / Western blot / Mechanism of action / Lymphocytes / Surgical / Culture Media / Adenocarcinoma / Immunoblotting / Fas Ligand

Expression of the Long Form of Human FLIP by Retroviral Gene Transfer of Hemopoietic Stem Cells Exacerbates Experimental Autoimmune Encephalomyelitis

Immunology / Stem Cells / Cytokines / Inflammation / Immunology of the Gut / Apoptosis / Humans / Mice / Chronic Disease / Female / Animals / Central Nervous System / The / Tumor necrosis factor-alpha / Myelin Proteins / Protein isoforms / Experimental Autoimmune Encephalomyelitis / Bone Marrow Cells / Hematopoietic Stem Cell Transplantation / Apoptosis / Humans / Mice / Chronic Disease / Female / Animals / Central Nervous System / The / Tumor necrosis factor-alpha / Myelin Proteins / Protein isoforms / Experimental Autoimmune Encephalomyelitis / Bone Marrow Cells / Hematopoietic Stem Cell Transplantation

Mitochondrial Transcription Factor B2 Is Essential for Metabolic Function in Drosophila melanogaster Development

Drosophila melanogaster / Mitochondria / Biological Chemistry / Apoptosis / Gene Silencing / Energy Metabolism / Biological Sciences / Longevity / Mitochondrial DNA / Animals / Biological / Glycolysis / Transcription Factor / CHEMICAL SCIENCES / Body Patterning / Oxidative phosphorylation / Larva / Body Weight / Cell Proliferation / Adenosine Triphosphate / Wing / Energy Metabolism / Biological Sciences / Longevity / Mitochondrial DNA / Animals / Biological / Glycolysis / Transcription Factor / CHEMICAL SCIENCES / Body Patterning / Oxidative phosphorylation / Larva / Body Weight / Cell Proliferation / Adenosine Triphosphate / Wing

Testosterone promotes apoptotic damage in human renal tubular cells

Nephrology / Urology / Dialysis / Apoptosis / Caspases / Cell line / Humans / Testosterone / Kidney / End Stage Renal Disease / Cell Death / Androgens / Morphological Analysis / Clinical Sciences / Caspase / Western blot / Androgen Receptor / Chronic Renal Disease / Primary Culture / Level / Proximal Tubule / Cell Survival / Propidium Iodide / Terminal Deoxynucleotidyl Transferase / Fas Ligand / Cell line / Humans / Testosterone / Kidney / End Stage Renal Disease / Cell Death / Androgens / Morphological Analysis / Clinical Sciences / Caspase / Western blot / Androgen Receptor / Chronic Renal Disease / Primary Culture / Level / Proximal Tubule / Cell Survival / Propidium Iodide / Terminal Deoxynucleotidyl Transferase / Fas Ligand

Pim-1 regulates cardiomyocyte survival downstream of Akt

Apoptosis / Humans / Mice / Animals / Cell nucleus / Rats / Myocardium / Postnatal development / Transgene Expression / Rats / Myocardium / Postnatal development / Transgene Expression

5′-AMINOIMIDAZOLE-4-CARBOXAMIDE Riboside Induces Apoptosis in Human Neuroblastoma Cells

Neuroscience / Psychology / Enzyme Inhibitors / Apoptosis / Caspases / Cell line / Cell Differentiation / Brain / Humans / Acetylcholine / Neurons / Differentiation / Enzyme / Norepinephrine / Caspase / Neuroblastoma / PBS / Retinoic Acid / Tretinoin / Protein Kinase / Bovine Serum Albumin / Neurosciences / Phorbol ester / Serum albumin / Cell line / Cell Differentiation / Brain / Humans / Acetylcholine / Neurons / Differentiation / Enzyme / Norepinephrine / Caspase / Neuroblastoma / PBS / Retinoic Acid / Tretinoin / Protein Kinase / Bovine Serum Albumin / Neurosciences / Phorbol ester / Serum albumin

Subtype-Specific MEK-PI3 Kinase Feedback as a Therapeutic Target in Pancreatic Adenocarcinoma

Transcription Factors / Apoptosis / Humans / microRNAs / Molecular Cancer Therapeutics / Molecular Targeted Therapy / Adenocarcinoma / Molecular Targeted Therapy / Adenocarcinoma

Aurora kinase inhibitor ZM447439 induces apoptosis via mitochondrial pathways

Flow Cytometry / Mitochondria / Apoptosis / Colorectal cancer / Humans / Cell Death / Kinase inhibitor / Biochemical / Time Dependent / BIOCHEMICAL PHARMACOLOGY / Aurora kinases / Mitochondrial Membrane Potential / Protein Kinase Inhibitors / Benzamides / Quinazolines / Cell Death / Kinase inhibitor / Biochemical / Time Dependent / BIOCHEMICAL PHARMACOLOGY / Aurora kinases / Mitochondrial Membrane Potential / Protein Kinase Inhibitors / Benzamides / Quinazolines

Hypoxia Response in Asthma

Inflammation / Asthma / Apoptosis / Signal Transduction / Chemokines and chemokine receptors / RNA interference / Mice / Animals / Male / Lung / RNA interference / Mice / Animals / Male / Lung

Natural plant extract tubeimoside I induces cytotoxicity via the mitochondrial pathway in human normal liver cells

Mitochondria / Saponins / Apoptosis / Cell line / Traditional Chinese Medicine / Humans / Caspase / Hepatocytes / Cell Proliferation / Triterpenes / Cucurbitaceae / Humans / Caspase / Hepatocytes / Cell Proliferation / Triterpenes / Cucurbitaceae

GPx8 peroxidase prevents leakage of H2O2 from the endoplasmic reticulum

Free Radicals / Protein Folding / Endoplasmic Reticulum Stress / Apoptosis / Humans / Reactive Oxygen Species / Animals / Glutathione Peroxidase / Pdi / Hydrogen Peroxide / Peroxidases / Redox / GFP / Oxidation-Reduction / Pns / Biochemistry and cell biology / Reactive Oxygen Species / Animals / Glutathione Peroxidase / Pdi / Hydrogen Peroxide / Peroxidases / Redox / GFP / Oxidation-Reduction / Pns / Biochemistry and cell biology

Bcl-xL Retrotranslocates Bax from the Mitochondria into the Cytosol

Protein Folding / Mitochondria / Apoptosis / Biological Sciences / Humans / Cell / Protein Conformation / Protein Transport / Cell / Protein Conformation / Protein Transport

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