Apoptosis

GPx8 peroxidase prevents leakage of H2O2 from the endoplasmic reticulum

Free Radicals / Protein Folding / Endoplasmic Reticulum Stress / Apoptosis / Humans / Reactive Oxygen Species / Animals / Glutathione Peroxidase / Pdi / Hydrogen Peroxide / Peroxidases / Redox / GFP / Oxidation-Reduction / Pns / Biochemistry and cell biology / Reactive Oxygen Species / Animals / Glutathione Peroxidase / Pdi / Hydrogen Peroxide / Peroxidases / Redox / GFP / Oxidation-Reduction / Pns / Biochemistry and cell biology

Bcl-2 activates a programme of premature senescence in human carcinoma cells

Cell Cycle / Apoptosis / Western blotting / Cell Division / Biological Sciences / Humans / Biochemical / Phenotype / CHEMICAL SCIENCES / Carcinoma / Doxycycline / Transfection / Cell Cycle Proteins / Humans / Biochemical / Phenotype / CHEMICAL SCIENCES / Carcinoma / Doxycycline / Transfection / Cell Cycle Proteins

From p63 to p53 across p73

Molecular Evolution / Membrane Proteins / DNA damage / Transcription Factors / Apoptosis / Protein-Protein Interaction / Humans / Animals / Complex network / Alternative splicing / Neoplasms / Alternative Splicing / Protein isoforms / Cell Proliferation / Cell Cycle Proteins / Gene Family / Protein Binding / DNA binding proteins / Biochemistry and cell biology / Protein-Protein Interaction / Humans / Animals / Complex network / Alternative splicing / Neoplasms / Alternative Splicing / Protein isoforms / Cell Proliferation / Cell Cycle Proteins / Gene Family / Protein Binding / DNA binding proteins / Biochemistry and cell biology

Mushroom Ganoderma lucidum Prevents Colitis-Associated Carcinogenesis in Mice

Inflammation / Macrophages / Apoptosis / Multidisciplinary / Humans / Mice / Animals / Hyperplasia / Carcinogens / Anti-inflammatory agents / PLoS one / Colitis / Plant extracts / Cell Proliferation / Imidazoles / Reishi / Mice / Animals / Hyperplasia / Carcinogens / Anti-inflammatory agents / PLoS one / Colitis / Plant extracts / Cell Proliferation / Imidazoles / Reishi

p85  deficiency protects  -cells from endoplasmic reticulum stress-induced apoptosis

Protein Folding / Oxidative Stress / Endoplasmic Reticulum Stress / Apoptosis / Multidisciplinary / Glucose / Hyperglycemia / Insulin / Mice / Pancreas / Animals / Endoplasmic Reticulum / Phenotype / Genotype / Time Factors / Type 2 Diabetes Mellitus / Protein Denaturation / Glucose / Hyperglycemia / Insulin / Mice / Pancreas / Animals / Endoplasmic Reticulum / Phenotype / Genotype / Time Factors / Type 2 Diabetes Mellitus / Protein Denaturation

Phenyl-N-tert-butylnitrone Demonstrates Broad-Spectrum Inhibition of Apoptosis-Associated Gene Expression in Endotoxin-Treated Rats

Apoptosis / Gene expression / Signal Transduction / Lipopolysaccharide / Liver / Septic Shock / Animals / Male / Spectrum / Gram-negative bacteria / Lipopolysaccharides / Rats / Wistar Rats / Nitrogen Oxides / Low molecular weight / Biochemistry and cell biology / Septic Shock / Animals / Male / Spectrum / Gram-negative bacteria / Lipopolysaccharides / Rats / Wistar Rats / Nitrogen Oxides / Low molecular weight / Biochemistry and cell biology

Ad-IRF-1 Induces Apoptosis in Esophageal Adenocarcinoma

Apoptosis / Cell separation / Cell line / Humans / Mice / Animals / Male / Cell Death / Neoplasia / Clinical Sciences / Neoplasms / Murine Model / Tumor Growth / Adenocarcinoma / Interferon gamma / Animals / Male / Cell Death / Neoplasia / Clinical Sciences / Neoplasms / Murine Model / Tumor Growth / Adenocarcinoma / Interferon gamma

Polyaspartylhydrazide Copolymer-Based Supramolecular Vesicular Aggregates as Delivery Devices for Anticancer Drugs

Engineering / Flow Cytometry / Polymers / Magnetic Resonance Spectroscopy / Apoptosis / Biological Sciences / Humans / Peptides / Drug Delivery Systems / High Pressure Liquid Chromatography / CHEMICAL SCIENCES / Drug Carriers / Biomacromolecules / Molecular Structure / Anticancer Drug / Biological Sciences / Humans / Peptides / Drug Delivery Systems / High Pressure Liquid Chromatography / CHEMICAL SCIENCES / Drug Carriers / Biomacromolecules / Molecular Structure / Anticancer Drug

LXR-α genomics programmes neuronal death observed in Alzheimer’s disease

Degenerative Diseases / Apoptosis / Epigenomics / Humans / Reactive Oxygen Species / Withanolides / Heme Oxygenase / Medical Physiology / Neurons / Neuroblastoma / Molecular cloning / Cellular Automaton Model / Neuronal Death / Human Serum / Orphan Nuclear Receptors / Recombinant Proteins / Alzheimer Disease / Biochemistry and cell biology / Gene Expression Regulation / Withanolides / Heme Oxygenase / Medical Physiology / Neurons / Neuroblastoma / Molecular cloning / Cellular Automaton Model / Neuronal Death / Human Serum / Orphan Nuclear Receptors / Recombinant Proteins / Alzheimer Disease / Biochemistry and cell biology / Gene Expression Regulation

LXR-α selectively reprogrammes cancer cells to enter into apoptosis

Cell Cycle / Degenerative Diseases / Apoptosis / Signal Transduction / Nuclear Receptor / RNA interference / Humans / Withanolides / T lymphocytes / Neoplasms / Biological Process / Orphan Nuclear Receptors / Protein Binding / Cell Survival / Antineoplastic Agents / Ligands / Molecular and Cellular Biochemistry / Response Elements / Biochemistry and cell biology / Gene expression profiling / RNA interference / Humans / Withanolides / T lymphocytes / Neoplasms / Biological Process / Orphan Nuclear Receptors / Protein Binding / Cell Survival / Antineoplastic Agents / Ligands / Molecular and Cellular Biochemistry / Response Elements / Biochemistry and cell biology / Gene expression profiling

Melatonin sensitizes human hepatoma cells to endoplasmic reticulum stress-induced apoptosis

Flow Cytometry / Immunohistochemistry / Apoptosis / Western blotting / Biological Sciences / Melatonin / Humans / Hepatocellular Carcinoma / Endoplasmic Reticulum / Pineal / Melatonin / Humans / Hepatocellular Carcinoma / Endoplasmic Reticulum / Pineal

DNA Damage and Activated Caspase-3 Expression in Neurons and Astrocytes: Evidence for Apoptosis in Frontotemporal Dementia

Psychology / Dementia / DNA damage / Apoptosis / Neuronal cell death / Caspases / Temporal Lobe / Brain / Humans / Female / Male / Astrocyte / Neurons / Astrocytes / Temporal Cortex / Clinical Sciences / Caspase / Aged / Middle Aged / Cell nucleus / Experimental / Frontotemporal Dementia / Degeneration / Glial Fibrillary Acidic Protein / Neurodegenerative Disease / Experimental Neurology / Sperm Dna Fragmentation / Neurosciences / Frontal Lobe / Behavioral symptoms / Gliosis / Caspases / Temporal Lobe / Brain / Humans / Female / Male / Astrocyte / Neurons / Astrocytes / Temporal Cortex / Clinical Sciences / Caspase / Aged / Middle Aged / Cell nucleus / Experimental / Frontotemporal Dementia / Degeneration / Glial Fibrillary Acidic Protein / Neurodegenerative Disease / Experimental Neurology / Sperm Dna Fragmentation / Neurosciences / Frontal Lobe / Behavioral symptoms / Gliosis

Drosophila microRNAs 263a/b Confer Robustness during Development by Protecting Nascent Sense Organs from Apoptosis

Scanning Electron Microscopy / Immunohistochemistry / Apoptosis / Biological Sciences / Drosophila / Mutation / Animals / microRNAs / Base Sequence / Mutation / Animals / microRNAs / Base Sequence

NMR exposure sensitizes tumor cells to apoptosis

Calcium / Magnetic Resonance Spectroscopy / Apoptosis / Humans / Medical Physiology / Magnetics / Monocytes / Neoplasms / Cell Survival / Plasma Membrane / White Blood Cell / Blood cells / Biochemistry and cell biology / Static Magnetic Field / Magnetics / Monocytes / Neoplasms / Cell Survival / Plasma Membrane / White Blood Cell / Blood cells / Biochemistry and cell biology / Static Magnetic Field

Drosophila E2F1 Has Context-Specific Pro- and Antiapoptotic Properties during Development

Drosophila melanogaster / DNA damage / Apoptosis / In Situ Hybridization / Biological Sciences / RNA interference / Neuropeptides / Mutation / Animals / RNA interference / Neuropeptides / Mutation / Animals

AML1/ETO sensitizes via TRAIL acute myeloid leukemia cells to the pro-apoptotic effects of hypoxia

Transcription Factors / Apoptosis / Signal Transduction / Antibodies / Acute Myeloid Leukemia / Humans / Caspase / Oxygen / Cell cycle checkpoints / Base Sequence / Protein Binding / Humans / Caspase / Oxygen / Cell cycle checkpoints / Base Sequence / Protein Binding
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