Apoptosis

Gene signature critical to cancer phenotype as a paradigm for anticancer drug discovery

Cancer / Cell Cycle / Drug Discovery / Apoptosis / Western blotting / Transcriptome / Mice / Animals / Oncogene / Phenotype / Clinical Sciences / Chromatin Immunoprecipitation / Antineoplastic Agents / Anticancer Drug / Transcriptome / Mice / Animals / Oncogene / Phenotype / Clinical Sciences / Chromatin Immunoprecipitation / Antineoplastic Agents / Anticancer Drug

BH3-only protein Noxa contributes to apoptotic control of stress-erythropoiesis

Cytokines / Membrane Proteins / Oxidative Stress / Apoptosis / Signal Transduction / Spleen / Cell Differentiation / Humans / Mice / Animals / Anemia / Bone marrow / Medical Physiology / Erythropoiesis / Biochemistry and cell biology / Gene Expression Regulation / Spleen / Cell Differentiation / Humans / Mice / Animals / Anemia / Bone marrow / Medical Physiology / Erythropoiesis / Biochemistry and cell biology / Gene Expression Regulation

Polyaspartylhydrazide Copolymer-Based Supramolecular Vesicular Aggregates as Delivery Devices for Anticancer Drugs

Engineering / Kinetics / Flow Cytometry / Polymers / Magnetic Resonance Spectroscopy / Cytotoxicity / Apoptosis / Biological Sciences / In Vitro / Humans / Peptides / Drug Delivery Systems / High Pressure Liquid Chromatography / CHEMICAL SCIENCES / Vesicle / Aqueous Solution / Drug Carriers / Biomacromolecules / Chemical Modification / Molecular Structure / Anticancer Drug / Cytotoxicity / Apoptosis / Biological Sciences / In Vitro / Humans / Peptides / Drug Delivery Systems / High Pressure Liquid Chromatography / CHEMICAL SCIENCES / Vesicle / Aqueous Solution / Drug Carriers / Biomacromolecules / Chemical Modification / Molecular Structure / Anticancer Drug

Novel cell death program leads to neutrophil extracellular traps

Electron Microscopy / Enzyme Inhibitors / Cell Biology / Innate immunity / Apoptosis / Biological Sciences / Antibodies / Humans / Reactive Oxygen Species / Cell Death / Staphylococcus aureus / Catalase / NADPH oxidase / Chromatin / Hydrogen Peroxide / Neutrophils / Nuclear envelope / Phagocytosis / Experimental Medicine / The cell / Cell Survival / Vacuoles / Biological Sciences / Antibodies / Humans / Reactive Oxygen Species / Cell Death / Staphylococcus aureus / Catalase / NADPH oxidase / Chromatin / Hydrogen Peroxide / Neutrophils / Nuclear envelope / Phagocytosis / Experimental Medicine / The cell / Cell Survival / Vacuoles

Adenovirus E3-6.7K Maintains Calcium Homeostasis and Prevents Apoptosis and Arachidonic Acid Release

Virology / Calcium / Membrane Proteins / Enzyme Inhibitors / Apoptosis / Biological Sciences / Humans / Endoplasmic Reticulum / P-glycoprotein / Calcium Homeostasis / Homeostasis / Transfection / Tumor Necrosis Factor–α (TNF) / Arachidonic Acid / Biological Sciences / Humans / Endoplasmic Reticulum / P-glycoprotein / Calcium Homeostasis / Homeostasis / Transfection / Tumor Necrosis Factor–α (TNF) / Arachidonic Acid

Mesenchymal stem cells control alloreactive CD8 + CD28 − T cells

Immunology / Apoptosis / Humans / Tumor necrosis factor-alpha / Cell Proliferation / Mesenchymal Stromal Cells / Interferon gamma / Mesenchymal Stromal Cells / Interferon gamma

T-588 inhibits astrocyte apoptosis via mitogen-activated protein kinase signal pathway

Apoptosis / Animals / Astrocyte / Kinase inhibitor / Phosphorylation / Astrocytes / Mitogen Activated Protein Kinase / Hydrogen Peroxide / European / Rats / Wistar Rats / Nerve Growth Factor / Reperfusion injury / MAP Kinase / Astrocytes / Mitogen Activated Protein Kinase / Hydrogen Peroxide / European / Rats / Wistar Rats / Nerve Growth Factor / Reperfusion injury / MAP Kinase

T-588 inhibits astrocyte apoptosis via mitogen-activated protein kinase signal pathway

Apoptosis / Animals / Astrocyte / Kinase inhibitor / Phosphorylation / Astrocytes / Mitogen Activated Protein Kinase / Hydrogen Peroxide / European / Rats / Wistar Rats / Nerve Growth Factor / Reperfusion injury / MAP Kinase / Astrocytes / Mitogen Activated Protein Kinase / Hydrogen Peroxide / European / Rats / Wistar Rats / Nerve Growth Factor / Reperfusion injury / MAP Kinase

4′-α-C-Branched N,O-nucleosides: synthesis and biological properties

Organic Chemistry / Magnetic Resonance Spectroscopy / Apoptosis / Cell line / Humans / Vinyl acetate / Bioorganic and medicinal Chemistry / Antiviral Activity / Nucleosides / Antiviral Agents / Vinyl acetate / Bioorganic and medicinal Chemistry / Antiviral Activity / Nucleosides / Antiviral Agents

Expressão de marcadores de proliferação celular e apoptose em carcinoma basocelular

Apoptosis / Humans / Clinical Sciences / Basal cell carcinoma / Cell Proliferation / Skin Neoplasms

Natriuretic Peptide Receptor A as a Novel Anticancer Target

Cancer / Inflammation / Immunohistochemistry / Nanoparticles / Ovarian Cancer / Apoptosis / RNA interference / Cancer Therapy / Mice / Female / Animals / Tumor Angiogenesis / NF-kappa B / Line / Retinoblastoma / Western blot / Neoplasms / Antitumor Activity / Tumor Growth / Guanylate Cyclase / Nude mice / Adenocarcinoma / Vascular Endothelial Growth Factor / retinoblastoma protein (RB1). / Skin Neoplasms / Apoptosis / RNA interference / Cancer Therapy / Mice / Female / Animals / Tumor Angiogenesis / NF-kappa B / Line / Retinoblastoma / Western blot / Neoplasms / Antitumor Activity / Tumor Growth / Guanylate Cyclase / Nude mice / Adenocarcinoma / Vascular Endothelial Growth Factor / retinoblastoma protein (RB1). / Skin Neoplasms

Natriuretic Peptide Receptor A as a Novel Target for Prostate Cancer

Immunohistochemistry / Prostate Cancer / Apoptosis / Molecular Biology Cancer / Cell line / Humans / Mice / Animals / Male / Peptides / Rats / Western blot / Disease Progression / Rabbits / Down-Regulation / Humans / Mice / Animals / Male / Peptides / Rats / Western blot / Disease Progression / Rabbits / Down-Regulation

Intracellular zinc increase inhibits p53−/− pancreatic adenocarcinoma cell growth by ROS/AIF-mediated apoptosis

Medical Microbiology / Mitochondria / Apoptosis / Pancreatic Cancer / Biological Sciences / Caspases / Humans / Reactive Oxygen Species / Cell Death / Physical sciences / Zinc / Gold Standard / Cell nucleus / Growth Inhibition / Cell Proliferation / Human Fibroblasts / Intracellular Space / Protein Transport / Biochemistry and cell biology / Adenocarcinoma / Cell Growth / PROTEASOME INHIBITOR / Caspases / Humans / Reactive Oxygen Species / Cell Death / Physical sciences / Zinc / Gold Standard / Cell nucleus / Growth Inhibition / Cell Proliferation / Human Fibroblasts / Intracellular Space / Protein Transport / Biochemistry and cell biology / Adenocarcinoma / Cell Growth / PROTEASOME INHIBITOR

TRAIL-induced programmed necrosis as a novel approach to eliminate tumor cells

Flow Cytometry / Apoptosis / Western blotting / Humans / Cell Death / Necrosis / Antineoplastic Agents / Necrosis / Antineoplastic Agents

Pim-1 regulates cardiomyocyte survival downstream of Akt

Apoptosis / Humans / Mice / Animals / Cell nucleus / Rats / Myocardium / Postnatal development / Transgene Expression / Rats / Myocardium / Postnatal development / Transgene Expression

Cardenolide Glycosides from Pergularia tomentosa and Their Proapoptotic Activity in Kaposi\'s Sarcoma Cells

Natural Products / Egypt / Pharmacognosy / Medicinal Plants / Cytotoxicity / Apoptosis / Structural Analysis / Biological Sciences / Cell line / Humans / ROOT / Cell Death / Plant Roots / CHEMICAL SCIENCES / Apoptose / Isolation / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Natural / Asclepiadaceae / Biological activity / Glycosides / Apoptosis / Structural Analysis / Biological Sciences / Cell line / Humans / ROOT / Cell Death / Plant Roots / CHEMICAL SCIENCES / Apoptose / Isolation / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Natural / Asclepiadaceae / Biological activity / Glycosides
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