Chemical Synthesis

A novel, broad-spectrum anticancer compound containing the imidazo[4,5-e][1,3]diazepine ring system

Organic Chemistry / Cytotoxicity / Ovarian Cancer / Cell line / In Vitro / Humans / Female / Male / Spectrum / Neoplasms / Biological activity / Ovary / Antitumor Activity / Structure activity Relationship / Chemical Synthesis / Antineoplastic Agents / Heterocyclic compounds / Humans / Female / Male / Spectrum / Neoplasms / Biological activity / Ovary / Antitumor Activity / Structure activity Relationship / Chemical Synthesis / Antineoplastic Agents / Heterocyclic compounds

Fmoc-protected iminosugar modified asparagine derivatives as building blocks for glycomimetics-containing peptides

Organic Chemistry / Multiple sclerosis / Glycopeptide Research / Humans / Statistical Significance / Peptides / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Secondary Structure / Antibody / Molecular Mimicry / Protein Conformation / Bioorganic and medicinal Chemistry / Asparagine / Chemical Synthesis / Enzyme Linked Immunosorbent Assay / Autoantibodies / Peptides / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Secondary Structure / Antibody / Molecular Mimicry / Protein Conformation / Bioorganic and medicinal Chemistry / Asparagine / Chemical Synthesis / Enzyme Linked Immunosorbent Assay / Autoantibodies

Novel imidazolopyrimidines as dual PI3-Kinase/mTOR inhibitors

Organic Chemistry / Signal Transduction / Cell line / In Vitro / Humans / Computer Simulation / Phosphorylation / Bioorganic and medicinal Chemistry / Growth Inhibition / Chemical Synthesis / Protein Kinase Inhibitors / Adenosine Triphosphate / Computer Simulation / Phosphorylation / Bioorganic and medicinal Chemistry / Growth Inhibition / Chemical Synthesis / Protein Kinase Inhibitors / Adenosine Triphosphate

Nanocomposites SnO2/Fe2O3: Sensor and catalytic properties

Materials Engineering / Analytical Chemistry / Gas Sensor / Iron Oxide / Continuous Flow / Chemical Synthesis

Potent 4-amino-5-azaindole factor VIIa inhibitors

Organic Chemistry / PT / Pyridines / Bioorganic and medicinal Chemistry / Structure activity Relationship / Chemical Synthesis / Serine Protease / Tissue Factor / Molecular Structure / Selectivity / Chemical Synthesis / Serine Protease / Tissue Factor / Molecular Structure / Selectivity

Aniline as a stabilizer for metal nanoparticles

Engineering / Nanocomposites / Nanomaterials / Nanoparticles / Reflux / Spectral analysis / Nanocomposite / XRD / Palladium / CHEMICAL SCIENCES / Rare earth metal oxide nanoparticle / Particle Size / Radiolysis / Chemical Synthesis / Gamma radiation / Spectral analysis / Nanocomposite / XRD / Palladium / CHEMICAL SCIENCES / Rare earth metal oxide nanoparticle / Particle Size / Radiolysis / Chemical Synthesis / Gamma radiation

Discovery of a series of aminopiperidines as novel iNOS inhibitors

Organic Chemistry / Enzyme Inhibitors / In Vitro / Humans / Amines / Blood Pressure / Drug Design / Active site / Nitric Oxide Synthase / Bioorganic and medicinal Chemistry / Structure activity Relationship / Isozyme / Chemical Synthesis / Selectivity / Piperidines / Blood Pressure / Drug Design / Active site / Nitric Oxide Synthase / Bioorganic and medicinal Chemistry / Structure activity Relationship / Isozyme / Chemical Synthesis / Selectivity / Piperidines

Discovery of a series of aminopiperidines as novel iNOS inhibitors

Organic Chemistry / Enzyme Inhibitors / In Vitro / Humans / Amines / Blood Pressure / Drug Design / Active site / Nitric Oxide Synthase / Bioorganic and medicinal Chemistry / Structure activity Relationship / Isozyme / Chemical Synthesis / Selectivity / Piperidines / Blood Pressure / Drug Design / Active site / Nitric Oxide Synthase / Bioorganic and medicinal Chemistry / Structure activity Relationship / Isozyme / Chemical Synthesis / Selectivity / Piperidines

Low temperature aqueous chemical synthesis of CdS sensitized ZnO nanorods

Engineering / Scanning Electron Microscopy / PHOTOELECTRON SPECTROSCOPY / Zinc Oxide / CHEMICAL SCIENCES / X ray diffraction / Chemical bath deposition / Low Temperature / Field Emission Scanning Electron Microscopy / X Ray Photoelectron Spectroscopy / Chemical Synthesis / Short Circuit Current / X ray diffraction / Chemical bath deposition / Low Temperature / Field Emission Scanning Electron Microscopy / X Ray Photoelectron Spectroscopy / Chemical Synthesis / Short Circuit Current

IRAK-4 inhibitors. Part III: A series of imidazo[1,2-a]pyridines

Organic Chemistry / Signal Transduction / In Vitro / Kinase inhibitor / Pyridines / Tnf alpha / Bioorganic and medicinal Chemistry / Structure activity Relationship / Chemical Synthesis / Protein Kinase Inhibitors / Molecular Structure / Tnf alpha / Bioorganic and medicinal Chemistry / Structure activity Relationship / Chemical Synthesis / Protein Kinase Inhibitors / Molecular Structure

IRAK-4 inhibitors. Part III: A series of imidazo[1,2- a]pyridines

Organic Chemistry / Signal Transduction / In Vitro / Kinase inhibitor / Pyridines / Tnf alpha / Bioorganic and medicinal Chemistry / Structure activity Relationship / Chemical Synthesis / Protein Kinase Inhibitors / Molecular Structure / Tnf alpha / Bioorganic and medicinal Chemistry / Structure activity Relationship / Chemical Synthesis / Protein Kinase Inhibitors / Molecular Structure

Novel polyester-polysaccharide nanoparticles

Nanoparticle / Polysaccharides / Nanotechnology / Pharmaceutical Chemistry / Stability / Dosage Form / Pharmaceutical / Solubility / Particle Size / Surface Properties / Freeze Drying / Emulsions / Molecular Mass / Polyesters / Drug Stability / Chemical Synthesis / Lyophilisation / Dosage Form / Pharmaceutical / Solubility / Particle Size / Surface Properties / Freeze Drying / Emulsions / Molecular Mass / Polyesters / Drug Stability / Chemical Synthesis / Lyophilisation

4-Amino-6-arylamino-pyrimidine-5-carbaldehyde hydrazones as potent ErbB-2/EGFR dual kinase inhibitors

Organic Chemistry / Modeling / Pharmacokinetics / Pharmaceutical Chemistry / Signal Transduction / Crystal structure / X Rays / In Vitro / Humans / Animals / Drug Design / Kinase inhibitor / Design Rationale / In Vivo / Hydrazones / Rats / Oximes / Molecular Model / Molecular Conformation / Bioorganic and medicinal Chemistry / Growth Factor / Structure activity Relationship / Chemical Synthesis / Protein Kinase Inhibitors / Receptor Tyrosine Kinase / Crystal structure / X Rays / In Vitro / Humans / Animals / Drug Design / Kinase inhibitor / Design Rationale / In Vivo / Hydrazones / Rats / Oximes / Molecular Model / Molecular Conformation / Bioorganic and medicinal Chemistry / Growth Factor / Structure activity Relationship / Chemical Synthesis / Protein Kinase Inhibitors / Receptor Tyrosine Kinase

Silicon monoxide assisted way to alpha-alumina nanostructures and their photoluminescence

Materials Engineering / Raw materials / Nanostructure / Luminescence / High Temperature / Thermal Decomposition / Reaction Rate / Chemical Synthesis / Thermal Decomposition / Reaction Rate / Chemical Synthesis

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