Drug Discovery - Page 3

A novel natural product compound enhances cAMP-regulated chloride conductance of cells expressing CFTR[delta]F508

Molecular Medicine / Cystic Fibrosis / Drug Discovery / Cell line / Humans / cyclic AMP / Natural Product / Chloride Channel / Genistein / Biological Factors / Protein Binding / Electric Conductivity / Plasma Membrane / Chemical Structure / Biochemistry and cell biology / Dimerization / cyclic AMP / Natural Product / Chloride Channel / Genistein / Biological Factors / Protein Binding / Electric Conductivity / Plasma Membrane / Chemical Structure / Biochemistry and cell biology / Dimerization

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Grid-Enabled High-Throughput <emphasis emphasistype=\"italic\">In Silico</emphasis> Screening Against Influenza A Neuraminidase

Biomedical Engineering / Drug Discovery / Virtual screening / influenza A / High throughput screening / Drug Design / Lessons Learned / Very high throughput / influenza A virus / Large Scale / In Silico / Electrical And Electronic Engineering / Drug Design / Lessons Learned / Very high throughput / influenza A virus / Large Scale / In Silico / Electrical And Electronic Engineering

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Natural Compounds\' Activity against Cancer Stem-Like or Fast-Cycling Melanoma Cells

Drug Discovery / Apoptosis / Multidisciplinary / Humans / Melanoma / Naphthoquinones / PLoS one / Cell cycle checkpoints / Cell Survival / Gene Expression Regulation / Naphthoquinones / PLoS one / Cell cycle checkpoints / Cell Survival / Gene Expression Regulation

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US academic drug discovery

Drug Discovery / Biological Sciences / Humans / United States / Universities

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Conserved Fungal Genes as Potential Targets for Broad-Spectrum Antifungal Drug Discovery

Computational Biology / Drug Discovery / Biological Sciences / Drug Design / Candida albicans / Spectrum / Antifungal Agents / Microbial Sensitivity Tests / Base Sequence / Eukaryotic Cell / Spectrum / Antifungal Agents / Microbial Sensitivity Tests / Base Sequence / Eukaryotic Cell

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Recombinant Environmental Libraries Provide Access to Microbial Diversity for Drug Discovery from Natural Products

Genetics / Drug Discovery / Microbial diversity / Multidisciplinary / Streptomyces / Escherichia coli / Applied / Applied Environmental Microbiology / Natural Product / Bacteria / Polymerase Chain Reaction / Soil Microbiology / High Pressure Liquid Chromatography / Molecular cloning / Anti-Bacterial Agents / Liquid Chromatography / Multienzyme complexes / Genetic Recombination / Genetic variation / Microbial Diversity / Biological activity / Amino Acid Sequence / Escherichia coli / Applied / Applied Environmental Microbiology / Natural Product / Bacteria / Polymerase Chain Reaction / Soil Microbiology / High Pressure Liquid Chromatography / Molecular cloning / Anti-Bacterial Agents / Liquid Chromatography / Multienzyme complexes / Genetic Recombination / Genetic variation / Microbial Diversity / Biological activity / Amino Acid Sequence

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Bermuda welcomes careful prospectors

Pharmacology / Biochemistry / Bioinformatics / Evolutionary Biology / Genetics / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Nanotechnology / Biodiversity / Research / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Signal Transduction / Astronomy / DNA / Bermuda / Cell Signalling / Medical Research / Earth Science / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Nanotechnology / Biodiversity / Research / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Signal Transduction / Astronomy / DNA / Bermuda / Cell Signalling / Medical Research / Earth Science

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Bermuda welcomes careful prospectors

Pharmacology / Biochemistry / Bioinformatics / Evolutionary Biology / Genetics / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Nanotechnology / Biodiversity / Research / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Signal Transduction / Astronomy / DNA / Bermuda / Cell Signalling / Medical Research / Earth Science / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Nanotechnology / Biodiversity / Research / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Signal Transduction / Astronomy / DNA / Bermuda / Cell Signalling / Medical Research / Earth Science

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How lipidomics provides new insight into drug discovery

Drug Discovery / Humans / Animals / Lipid metabolism / Neoplasms / Antineoplastic Agents / #Hypolipidemic Agents / Antineoplastic Agents / #Hypolipidemic Agents

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Gene signature critical to cancer phenotype as a paradigm for anticancer drug discovery

Cancer / Cell Cycle / Drug Discovery / Apoptosis / Western blotting / Transcriptome / Epidermal Growth Factor/ErbB receptors / Mice / Animals / Oncogene / Phenotype / Clinical Sciences / Chromatin Immunoprecipitation / Antineoplastic Agents / Anticancer Drug / Transcriptome / Epidermal Growth Factor/ErbB receptors / Mice / Animals / Oncogene / Phenotype / Clinical Sciences / Chromatin Immunoprecipitation / Antineoplastic Agents / Anticancer Drug

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Spectral analysis of microarray gene expression time series data of Plasmodium falciparum

Bioinformatics / Algorithms / Drug Discovery / Gene expression / Signal Transduction / Biological Sciences / Computer Simulation / Mathematical Sciences / Animals / Time Series Data / Singular Spectrum Analysis / Plasmodium falciparum / Bioinformatics applications / Protozoan Proteins / Gene expression profiling / Biological Sciences / Computer Simulation / Mathematical Sciences / Animals / Time Series Data / Singular Spectrum Analysis / Plasmodium falciparum / Bioinformatics applications / Protozoan Proteins / Gene expression profiling

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The Arctic paradox

Pharmacology / Biochemistry / Bioinformatics / Evolutionary Biology / Genetics / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Nanotechnology / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Signal Transduction / Astronomy / DNA / Cell Signalling / Medical Research / Earth Science / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Nanotechnology / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Signal Transduction / Astronomy / DNA / Cell Signalling / Medical Research / Earth Science

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Schistosomiasis control: praziquantel forever?

Drug Discovery / Biological Sciences / Humans / Resistance / Schistosomiasis / Animals / Drug Resistance / Schistosoma Mansoni / Praziquantel / Animals / Drug Resistance / Schistosoma Mansoni / Praziquantel

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Passive Transdermal Systems Whitepaper Incorporating Current Chemistry, Manufacturing and Controls (CMC) Development Principles

Education / Drug Discovery / Pharmaceutical Chemistry / Humans / Animals / Drug Delivery Systems / AAPS PharmSciTech / Drug Industry / Pharmaceutical preparations / Drug Delivery Systems / AAPS PharmSciTech / Drug Industry / Pharmaceutical preparations

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Discovery of ectoparasiticidal hydrazonotrifluoromethanesulfonanilides

Organic Chemistry / Drug Discovery / Cats / Dogs / Animals / Hydrazones / Bioorganic and medicinal Chemistry / Structure activity Relationship / Rhipicephalus sanguineus / Hydrazones / Bioorganic and medicinal Chemistry / Structure activity Relationship / Rhipicephalus sanguineus

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The TB Structural Genomics Consortium: A decade of progress

Genomics / Drug Discovery / International Cooperation / Structural Genomics / Macromolecular X-Ray Crystallography / Tuberculosis / Humans / Mycobacterium tuberculosis / SAXS / TB / Nmr / Magnetic Resonance / Drug Design / PPI / Protein structure / Protein Interaction / NAD / X Ray Crystallography / PDB / Tuberculosis / Humans / Mycobacterium tuberculosis / SAXS / TB / Nmr / Magnetic Resonance / Drug Design / PPI / Protein structure / Protein Interaction / NAD / X Ray Crystallography / PDB

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