Haploinsufficiency

Induced Pluripotent Stem Cell Models of Progranulin-Deficient Frontotemporal Dementia Uncover Specific Reversible Neuronal Defects

Cell line / Humans / Mutation / Microglia / Neurons / Haploinsufficiency / Frontotemporal Dementia / Induced Pluripotent Stem Cells / Staurosporine / Protein Kinase Inhibitors / Down-Regulation / Haploinsufficiency / Frontotemporal Dementia / Induced Pluripotent Stem Cells / Staurosporine / Protein Kinase Inhibitors / Down-Regulation

Induced Pluripotent Stem Cell Models of Progranulin-Deficient Frontotemporal Dementia Uncover Specific Reversible Neuronal Defects

Cell line / Humans / Mutation / Microglia / Neurons / Haploinsufficiency / Frontotemporal Dementia / Induced Pluripotent Stem Cells / Staurosporine / Protein Kinase Inhibitors / Down-Regulation / Haploinsufficiency / Frontotemporal Dementia / Induced Pluripotent Stem Cells / Staurosporine / Protein Kinase Inhibitors / Down-Regulation

Induced Pluripotent Stem Cell Models of Progranulin-Deficient Frontotemporal Dementia Uncover Specific Reversible Neuronal Defects

Cell line / Humans / Mutation / Microglia / Neurons / Haploinsufficiency / Frontotemporal Dementia / Induced Pluripotent Stem Cells / Staurosporine / Protein Kinase Inhibitors / Down-Regulation / Haploinsufficiency / Frontotemporal Dementia / Induced Pluripotent Stem Cells / Staurosporine / Protein Kinase Inhibitors / Down-Regulation

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