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Mutation
Mutation
Base Pairing Constraints Drive Structural Epistasis in Ribosomal RNA Sequences
Evolutionary Biology / Genetics / Coevolution / Molecular Evolution / Sequence alignment / Mutation / Archaea / Bacteria / Molecular biology and evolution / Epistasis / ribosomal RNA / Hydrogen Bonding / Base Sequence / Nucleic Acid Conformation / Biochemistry and cell biology / Molecular Structure / Mutation / Archaea / Bacteria / Molecular biology and evolution / Epistasis / ribosomal RNA / Hydrogen Bonding / Base Sequence / Nucleic Acid Conformation / Biochemistry and cell biology / Molecular Structure
Mitochondria as determinant of nucleotide pools and chromosomal stability
Mitochondria / DNA repair / Cell line / Mitochondrial DNA / Humans / Mutation / Mitochondrial Genome / Comet Assay / Mitochondrial dysfunction / HeLa cells / Human Disease / Chromosomal Instability / Nucleotides / Mutation / Mitochondrial Genome / Comet Assay / Mitochondrial dysfunction / HeLa cells / Human Disease / Chromosomal Instability / Nucleotides
Proteomic analysis of mitochondria from senescent Podospora anserina casts new light on ROS dependent aging mechanisms
Aging / Proteomics / Oxidative Stress / Mitochondria / Signal Transduction / Mutation / Reactive Oxygen Species / Tandem Mass Spectrometry / Phenotype / Genotype / Mitochondrial Proteins / Mutation / Reactive Oxygen Species / Tandem Mass Spectrometry / Phenotype / Genotype / Mitochondrial Proteins
RUNX2 analysis of Danish cleidocranial dysplasia families
Genetics / Denmark / Humans / Mutation / Female / Clinical Genetics / Male / Genetic Association Studies / Gene Order / Pedigree / Phenotype / Clinical Sciences / Genotype / Adult / Amino Acid Substitution Rates / Cohort Studies / Clinical Genetics / Male / Genetic Association Studies / Gene Order / Pedigree / Phenotype / Clinical Sciences / Genotype / Adult / Amino Acid Substitution Rates / Cohort Studies
How do some haemophiliacs develop inhibitors?
Antibodies / Haemophilia / Humans / Mutation / Clinical Sciences / Hemophilia A / factor VIII / Hemophilia A / factor VIII
Comprehensive molecular profiling of lung adenocarcinoma
Genomics / Multidisciplinary / Nature / Transcriptome / Molecular typing / Humans / Mutation / Female / Male / Gene Dosage / Oncogenes / Sex Factors / Cell Cycle Proteins / Adenocarcinoma / Humans / Mutation / Female / Male / Gene Dosage / Oncogenes / Sex Factors / Cell Cycle Proteins / Adenocarcinoma
Natural Variants of Photosystem II Subunit D1 Tune Photochemical Fitness to Solar Intensity
Molecular Evolution / Kinetics / Photosynthesis / Biomass / Cyanobacteria / Biological Chemistry / Biological Sciences / Fourier Analysis / Solar Energy / Mutation / Chlorophyll / Light / CHEMICAL SCIENCES / Chlamydomonas / Oxygen / Genetic variation / Protein isoforms / Oxidation-Reduction / Biological Chemistry / Biological Sciences / Fourier Analysis / Solar Energy / Mutation / Chlorophyll / Light / CHEMICAL SCIENCES / Chlamydomonas / Oxygen / Genetic variation / Protein isoforms / Oxidation-Reduction
DNA-PKcs and ATM co-regulate DNA double-strand break repair
Regulation / HR / Radiobiology of Ionizing Radiation / DNA damage / DNA repair / Stability / Ir / Mutation / Animals / Kinase inhibitor / Phosphorylation / Genome / Genetic Recombination / Homologous Recombination / Protein Kinase / Ionizing Radiation / Cell Cycle Proteins / DNA binding proteins / Biochemistry and cell biology / Nhej / DNA double strand breaks / Stability / Ir / Mutation / Animals / Kinase inhibitor / Phosphorylation / Genome / Genetic Recombination / Homologous Recombination / Protein Kinase / Ionizing Radiation / Cell Cycle Proteins / DNA binding proteins / Biochemistry and cell biology / Nhej / DNA double strand breaks
RUNX2 analysis of Danish cleidocranial dysplasia families
Genetics / Denmark / Humans / Mutation / Female / Clinical Genetics / Male / Genetic Association Studies / Gene Order / Pedigree / Phenotype / Clinical Sciences / Genotype / Adult / Amino Acid Substitution Rates / Cohort Studies / Clinical Genetics / Male / Genetic Association Studies / Gene Order / Pedigree / Phenotype / Clinical Sciences / Genotype / Adult / Amino Acid Substitution Rates / Cohort Studies
Atypical, slowly progressive behavioural variant frontotemporal dementia associated with C9ORF72 hexanucleotide expansion
Neurology / Amyotrophic Lateral Sclerosis / Brain Mapping / Humans / Mutation / Female / Male / Proteins / Middle Aged / Frontotemporal Dementia / Alzheimer Disease / Female / Male / Proteins / Middle Aged / Frontotemporal Dementia / Alzheimer Disease
The Escherichia coli Lpt Transenvelope Protein Complex for Lipopolysaccharide Export Is Assembled via Conserved Structurally Homologous Domains
Bacteriology / Membrane Proteins / Biological Sciences / Mutation / Escherichia coli / Lipopolysaccharides
Dyskeratosis congenita as a disorder of telomere maintenance
Telomerase / Humans / Mutation / TELOMERE SHORTENING / Cell Cycle Proteins
Comprehensive molecular profiling of lung adenocarcinoma
Genomics / Multidisciplinary / Nature / Transcriptome / Molecular typing / Humans / Mutation / Female / Male / Gene Dosage / Oncogenes / Sex Factors / Cell Cycle Proteins / Adenocarcinoma / Humans / Mutation / Female / Male / Gene Dosage / Oncogenes / Sex Factors / Cell Cycle Proteins / Adenocarcinoma
Protein PknE, a novel transmembrane eukaryotic-like serine/threonine kinase from Mycobacterium tuberculosis
Signal Transduction / Mycobacterium tuberculosis / Protein Kinases / Mutation / Threonine / Phosphorylation / Biochemical / Plasmids / Enzyme / Lysine / Glutathione Transferase / Protein Phosphorylation / Protein Kinase / Cytoplasm / Site-directed Mutagenesis / Full Length Movies / Biochemistry and cell biology / Cell Membrane / Phosphorylation / Biochemical / Plasmids / Enzyme / Lysine / Glutathione Transferase / Protein Phosphorylation / Protein Kinase / Cytoplasm / Site-directed Mutagenesis / Full Length Movies / Biochemistry and cell biology / Cell Membrane
NKX3.1 Activates Cellular Response to DNA Damage
Cancer / DNA damage / DNA repair / Transcription Factors / Apoptosis / Signal Transduction / In Vitro / Humans / Protein Kinases / Mutation / Male / Phosphorylation / Cell nucleus / Cell Cycle Proteins / Signal Transduction / In Vitro / Humans / Protein Kinases / Mutation / Male / Phosphorylation / Cell nucleus / Cell Cycle Proteins
Stem cells in melanoma development
Adult Stem Cells / Humans / Mutation / Melanoma / Animals / Melanocytes / Skin Neoplasms / Melanocytes / Skin Neoplasms
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