Signal Transduction

Caspase-1 as a radio- and chemo-sensitiser in vitro and in vivo

Molecular Medicine / Mitochondria / Gamma Rays / Apoptosis / Signal Transduction / Molecular / Humans / Mice / Female / Animals / Male / Caspase / Cisplatin / HeLa cells / Transfection / Cell Survival / Antineoplastic Agents / Molecular / Humans / Mice / Female / Animals / Male / Caspase / Cisplatin / HeLa cells / Transfection / Cell Survival / Antineoplastic Agents

Cryptosporidium parvum-induced ileo-caecal adenocarcinoma and WNT signaling in a rodent model

Signal Transduction / Biological Sciences / Mice / Animals / Beta-Catenin / Adenocarcinoma

A Molecular Basis for Human Embryonic Stem Cell Pluripotency

Technology / Human Development / Forecasting / Induced Pluripotent Stem Cells (I Psc) / Human embryonic stem cell / Stem Cell / Molecular Mechanics / Signal Transduction / Biological Sciences / Humans / Wnt Signaling / Animals / Embryonic Stem Cell / Embryonic Stem Cells / Transforming Growth Factor Beta / Cell Fate / Stem Cell / Molecular Mechanics / Signal Transduction / Biological Sciences / Humans / Wnt Signaling / Animals / Embryonic Stem Cell / Embryonic Stem Cells / Transforming Growth Factor Beta / Cell Fate

Semisynthetic Hydrophilic Polyals

Engineering / Tissue Engineering / Kinetics / Carbon / Polysaccharides / Polymers / Magnetic Resonance Spectroscopy / Signal Transduction / Biological Sciences / Mice / Animals / Male / Temperature / CHEMICAL SCIENCES / Rats / Oxygen / Time Factors / CARBOHYDRATES / Cations / Hydrolysis / Biocompatible Materials / Hydrogen-Ion Concentration / Biomacromolecules / Oligosaccharides / Polymers / Magnetic Resonance Spectroscopy / Signal Transduction / Biological Sciences / Mice / Animals / Male / Temperature / CHEMICAL SCIENCES / Rats / Oxygen / Time Factors / CARBOHYDRATES / Cations / Hydrolysis / Biocompatible Materials / Hydrogen-Ion Concentration / Biomacromolecules / Oligosaccharides

Do glucocorticoids participate in thymocyte development?

Immunology / Signal Transduction / Humans / Mice / Animals / T cell development / Glucocorticoids / T cell development / Glucocorticoids

Psychosis pathways converge via D2High dopamine receptors

Cognitive Science / Schizophrenia / STEROIDS / Signal Transduction / Dopamine / Synapse / Humans / Mice / Animals / dopamine receptor D4 / Animal Model / Brain injury / Tyrosine Hydroxylase / Cesarean Section / Biological markers / Psychotic Disorders / Neural pathways / G protein / Genetic Markers / Neurosciences / Synapse / Humans / Mice / Animals / dopamine receptor D4 / Animal Model / Brain injury / Tyrosine Hydroxylase / Cesarean Section / Biological markers / Psychotic Disorders / Neural pathways / G protein / Genetic Markers / Neurosciences

The Cdc14B-Cdh1-Plk1 Axis Controls the G2 DNA-Damage-Response Checkpoint

DNA damage / DNA repair / Signal Transduction / Biological Sciences / Mitosis / Humans / Cell / Cell nucleus / DNA damage response / Neoplasms / Signaling / Cell Cycle Proteins / Humans / Cell / Cell nucleus / DNA damage response / Neoplasms / Signaling / Cell Cycle Proteins

Cycloartane triterpenoids from Cimicifuga yunnanensis induce apoptosis of breast cancer cells (MCF7) via p53-dependent mitochondrial signaling pathway

Mitochondria / Apoptosis / Signal Transduction / Biological Sciences / Phytotherapy / Humans / Female / Caspase / CHEMICAL SCIENCES / Triterpenes / Breast Cancer Cells / Humans / Female / Caspase / CHEMICAL SCIENCES / Triterpenes / Breast Cancer Cells

Significance of sterol structural specificity

Biological Chemistry / Signal Transduction / Biological Sciences / Insulin / Cholesterol / Animals / Biological / CHEMICAL SCIENCES / Oral Hypoglycemic Agents / Lipid bilayers / Detergents / Subcellular Fractions / Animals / Biological / CHEMICAL SCIENCES / Oral Hypoglycemic Agents / Lipid bilayers / Detergents / Subcellular Fractions

Skeletal muscle expresses the extracellular cyclic AMP-adenosine pathway

Skeletal muscle biology / British / Cell Signaling / Signal Transduction / Adenosine / G protein-coupled receptors / cyclic AMP / Animals / Plant tissue Culture Techniques / Male / High Pressure Liquid Chromatography / Skeletal Muscle / Rats / Adenosine Receptors / Radioligand Assay / Wistar Rats / Ligands / Extracellular Space / Adenosine monophosphate / G protein-coupled receptors / cyclic AMP / Animals / Plant tissue Culture Techniques / Male / High Pressure Liquid Chromatography / Skeletal Muscle / Rats / Adenosine Receptors / Radioligand Assay / Wistar Rats / Ligands / Extracellular Space / Adenosine monophosphate

CELLULAR RESPONSES TO DNA DAMAGE

Engineering / Pharmacology / Environmental Health / Radiation Biology / Cell Cycle / DNA damage / DNA repair / Apoptosis / Signal Transduction / Biological Sciences / DNA / Environmental Sciences / Humans / Mutagenesis / Mutation / Escherichia coli / Animals / Cell Death / Pharmacology and toxicology / Fission yeast / Nucleotide Excision Repair / Public health systems and services research / DNA damage response / UV light / Genomic instability / Cell cycle checkpoints / Veterinary Sciences / Ionizing Radiation / Cell Survival / Mutagens / Base Excision Repair / Biochemistry and cell biology / DNA damage / DNA repair / Apoptosis / Signal Transduction / Biological Sciences / DNA / Environmental Sciences / Humans / Mutagenesis / Mutation / Escherichia coli / Animals / Cell Death / Pharmacology and toxicology / Fission yeast / Nucleotide Excision Repair / Public health systems and services research / DNA damage response / UV light / Genomic instability / Cell cycle checkpoints / Veterinary Sciences / Ionizing Radiation / Cell Survival / Mutagens / Base Excision Repair / Biochemistry and cell biology

Erythropoiesis: Model systems, molecular regulators, and developmental programs

Signal Transduction / Hematopoietic Stem Cells / Cell line / Cell Differentiation / Humans / Mice / Animals / Behavioral Animal Models / Erythropoiesis / Model System / Biochemistry and cell biology / Gene Expression Regulation / Mice / Animals / Behavioral Animal Models / Erythropoiesis / Model System / Biochemistry and cell biology / Gene Expression Regulation

A Smad3 transgenic reporter reveals TGF-beta control of zebrafish spinal cord development

Developmental Biology / Cell Cycle / Immunohistochemistry / Signal Transduction / Transcription / Biological Sciences / Animals / Spinal Cord / Neurons / Phenotype / Reporter / Transforming Growth Factor Beta / Zebrafish / Transgenic / Cell Proliferation / Biological Sciences / Animals / Spinal Cord / Neurons / Phenotype / Reporter / Transforming Growth Factor Beta / Zebrafish / Transgenic / Cell Proliferation

Arabidopsis WEE1 Kinase Controls Cell Cycle Arrest in Response to DNA Damage

Genetics / Plant Biology / Cell Cycle / DNA replication / DNA damage / DNA repair / Signal Transduction / Phosphorylation / Arabidopsis / Seedling / Plant cell / Hydroxyurea / Cell Cycle Arrest / Cell Cycle Proteins / Biochemistry and cell biology / DNA repair / Signal Transduction / Phosphorylation / Arabidopsis / Seedling / Plant cell / Hydroxyurea / Cell Cycle Arrest / Cell Cycle Proteins / Biochemistry and cell biology

Lysyl Oxidase is Essential for Hypoxia-Induced Metastasis

Pharmacology / Biochemistry / Bioinformatics / Evolutionary Biology / Genetics / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Breast Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Hypoxia / Nanotechnology / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Signal Transduction / Astronomy / DNA / Head and Neck / Humans / Mice / Female / Animals / Cell Signalling / Medical Research / Survival Rate / Neoplasms / Disease Progression / Earth Science / Overall Survival / Focal Adhesion Kinase / lysyl oxidase / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Breast Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Hypoxia / Nanotechnology / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Signal Transduction / Astronomy / DNA / Head and Neck / Humans / Mice / Female / Animals / Cell Signalling / Medical Research / Survival Rate / Neoplasms / Disease Progression / Earth Science / Overall Survival / Focal Adhesion Kinase / lysyl oxidase

Lysyl oxidase is essential for hypoxia-induced metastasis

Pharmacology / Biochemistry / Bioinformatics / Evolutionary Biology / Genetics / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Breast Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Hypoxia / Nanotechnology / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Signal Transduction / Astronomy / DNA / Head and Neck / Humans / Mice / Female / Animals / Cell Signalling / Medical Research / Survival Rate / Neoplasms / Disease Progression / Earth Science / Overall Survival / Focal Adhesion Kinase / lysyl oxidase / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Breast Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Hypoxia / Nanotechnology / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Signal Transduction / Astronomy / DNA / Head and Neck / Humans / Mice / Female / Animals / Cell Signalling / Medical Research / Survival Rate / Neoplasms / Disease Progression / Earth Science / Overall Survival / Focal Adhesion Kinase / lysyl oxidase
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