JOURNAL OF THE AMERICAN HEART ASSOCIATION
A Citywide Prehospital Protocol Increases Access to Stroke Thrombolysis in Toronto David J Gladstone, Lance H Rodan, Demetrios J Sahlas, Liesly Lee, Brian J Murray, Jon E Ween, James R Perry, Jordan Chenkin, Laurie Morrison, Shann Beck, and Sandra E Black STROKE/2008/540377 VERSION 2
This information is current as of January 11, 2009
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Author Disclosures David J Gladstone: No disclosures Lance H Rodan: No disclosures Demetrios J Sahlas: No disclosures Liesly Lee: No disclosures Brian J Murray: No disclosures Jon E Ween: No disclosures James R Perry: No disclosures Jordan Chenkin: No disclosures Laurie Morrison: No disclosures Shann Beck: No disclosures Sandra E Black: No disclosures
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Revised Manuscript 513333
A Citywide Prehospital Protocol Increases Access to Stroke Thrombolysis in Toronto David J. Gladstone, Lance H. Rodan, Demetrios J. Sahlas, Liesly Lee, Brian J. Murray, Jon E. Ween, James R. Perry, Jordan Chenkin, Laurie Morrison, Shann Beck, Sandra E. Black From the North and East GTA-Ontario Regional Stroke Centre and Division of Neurology, Department of Medicine and Neurosciences Program, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
Address for Correspondence: David J. Gladstone MD, PhD, FRCPC Sunnybrook Health Sciences Centre 2075 Bayview Avenue, Room A442 Toronto, Ontario, Canada M4N 3M5 Tel 416-480-4866 FAX 416-480-5753 Email
[email protected]
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ACKNOWLEDGEMENTS
The authors gratefully acknowledge the Ontario Stroke System of the Ontario Ministry of Health and Long-Term Care, the Toronto Regional Stroke Centres, the Heart and Stroke Foundation of Ontario, Toronto Emergency Medical Services, Sunnybrook Osler Centre for Prehospital Care, and the Registry of the Canadian Stroke Network. Dr. Gladstone is supported by the Heart and Stroke Foundation of Ontario, the Heart and Stroke Foundation Centre for Stroke Recovery, and the Department of Medicine (Sunnybrook Health Sciences Centre and University of Toronto).
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A Citywide Prehospital Protocol Increases Access to Stroke Thrombolysis in Toronto
Cover title: Immediate Impact of a Prehospital Stroke Protocol Word count: abstract 280; text 1889; total including references 2855 Figures: 0 Tables: 1 Key words: stroke; prehospital; ambulance; thrombolysis
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Page 4 of 13 ABSTRACT
Background – Intravenous tissue plasminogen activator (tPA) for ischemic stroke is effective for eligible patients who can be treated within a 3-hour window, but treatment rates remain disappointingly low, often
